Intern
    THE BRINGMANN GROUP: BIOACTIVE COMPOUNDS FROM NATURE

    Publications and Patents*

     

     

    2017

    722)

    B. K. Lombe, T. Bruhn, D. Feineis, V. Mudogo, R. Brun, G. Bringmann; Antiprotozoal spiro-Mbandakamines A1 and A2, Fused Naphthylisoquinoline Dimers from a Congolese Ancistrocladus PlantOrg. Lett. 2017, DOI: 10.1021/acs.orglett.7b03473.    

    721)

    S. Fayez, D. Feineis, V. Mudogo, S. Awale, G. Bringmann; Ancistrolikokines E-H and Related 5,8'-Coupled Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus likoko with Antiausterity Activities against PANC-1 Human Pancreatic Cancer Cells; RSC Adv. 2017, 7, 53740-53751.  

    720) 

    R. Domes, Ch. Domes, Ch. Albert, G. Bringmann, J. Popp, T. Frosch; Vibrational spectroscopic characterization of antileishmanial arylisoquinolines by means of Raman spectroscopy and density functional theory calculations; Phys. Chem. Chem. Phys. (RSC201719, 29918-29926.  

    719) 

    J. Li, R. Seupel, T. Bruhn, D. Feineis, M. Kaiser, R. Brun, V. Mudogo, S. Awale, G. Bringmann; Jozilebomines A and B, Naphthylisoquinoline Dimers From the Congolese Liana Ancistrocladus ileboensis, with Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line; J. Nat. Prod. 201780, 2807–2817.

    718) 

    R. Sharma, E. Candelario-Jalil, D. Feineis, G. Bringmann, B.L. Fiebich, R.S. Akundi; 1-Trichloromethyl-1,2,3,4-tetrahydro-β-carboline (TaClo) Alters Cell Cycle Progression in Human Neuroblastoma Cell Lines; Neurotoxicity Research 201732, 649-660.

    717)

    G. Bringmann, R. Seupel, D. Feineis, M. Xu, G. Zhang, M. Kaiser, R. Brun, E.-J. Seo, T. Efferth; Antileukemic ancistrobenomine B and related 5,1'-Coupled naphthylisoquinoline alkaloids from the Chinese liana Ancistrocladus tectorius; Fitoterapia 2017121, 76-89.

    716)

    G. Bringmann, J. Bobineau, K. Sekora; BEBUC: Bila elimu hakuna maendeleo na amani (Ohne Bildung kein Wohlstand und Frieden) - Eine neue Generation von Professoren für den Kongo; Schriftenreihe des Forums Afrikazentrum der Universität Würzburg zum Africa Festival, May 2017. {Es gelten die urheberrechtlichen Regeln für wissenschaftliche Arbeiten}

    715)

    D.T. Tshitenge, D. Feineis, V. Mudogo, M. Kaiser, R. Brun, G. Bringmann; Antiplasmodial Ealapasamines A-C, Mixed Naphthylisoquinoline Dimers from the Central African Liana Ancistrocladus ealaensis; Sci. Rep. 2017, 7:e5767.

    714)

    C. Schies, A.B. Alemayehu, H. Vazquez-Lima, K.E. Thomas, T. Bruhn, G. Bringmann, A. Ghosh; Metallocorroles as inherently chiral chromophores: Resolution and electronic circular dichroism spectroscopy of a tungsten biscorrole; Chem. Commun. 2017, 53, 6121-6124.

    713)

    D.T. Tshitenge, D. Feineis, S. Awale, G. Bringmann; Gardenifolins A-H, Scalemic Neolignans from Gardenia ternifolia: Chiral Resolution, Configurational Assignment, and Cytotoxic Activities Against the HeLa Cancer Cell Line; J. Nat. Prod. 2017, 80, 1604-1614.

    712)

    B.K. Lombe, T. Bruhn, D. Feineis, V. Mudogo, R. Brun, G. Bringmann; Cyclombandakamines A1, and A2, Oxygen-Bridged Naphthylisoquinoline dimers, from a Congolese Ancistrocladus Liana; Org. Lett. 2017, 19, 1342-1345.

    711)

    J. Li, R. Seupel, D. Feineis, V. Mudogo, M. Kaiser, R. Brun, D. Brunnert, M. Chatterjee, E.-J. Seo, T. Efferth, G. Bringmann; Dioncophyllines C2, D2, and F, and Related Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus ileboensis, with Potent Activities against Plasmodium falciparum, and against Multiple Myeloma and Leukemia Cell Lines; J. Nat. Prod. 2017, 80, 443-458.

    710)W. Li, J. Wu, T. Satyanandamurty, L. Shen, G. Bringmann; Krishnadimer A, an Axially Chiral Non-Biaryl Natural Product: Isolation and Biomimetic Synthesis; Org. Lett. 2017, 19, 182-185.
    709)C. Lieberherr, G. Zhang, K. Singethan, S. Kendl, V. Vogt, J. Maier, G. Bringmann, J. Schneider-Schaulies; The Natural Plant Naphthoquinone Droserone Inhibits Measles Virus Infection; Planta Med. 2017, 83, 232-238.

    2016

    708)

    R. Seupel, B. Hertlein-Amslinger, T. Gulder, P. Stawski, M. Kaiser, R. Brun, G. Bringmann; Directed Synthesis of All Four Pure Stereoisomers of the N,C-Coupled Naphthylisoquinoline Alkaloid Ancistrocladinium A; Org. Lett. 2016, 18, 6508-6511.

    707)

    A. Goel, V. Kumar, Y. Hemberger, F.V. Singh, P. Nag, M. Knauer, R. Kant, R. Raghunandan, P.R. Maulik, G. Bringmann; Rotationally Hindered Biphenyls and Terphenyls: Synthesis, Molecular Dynamics, and Configurational Assignment; J. Org. Chem. 2016, 81, 10721-10732.

    706)

    M. Arrowsmith, D. Auerhammer, R. Bertermann, H. Braunschweig, G. Bringmann, M. A. Celik, R. D. Dewhurst, M. Finze, M. Grüne, M. Hailmann, T. Hertle, I. Krummenacher; Generation of Dicoordinate Boron(I) Units by Fragmentation of a Tetra-Boron(I) Molecular Square; Angew. Chem., Int. Ed. 2016, 55, 14464-14468; Angew. Chem. 2016, 128, 14680-14684.

    705)

    G. Bringmann, R. Seupel, D. Feineis, G. Zhang, M. Xu, J. Wu, M. Kaiser, R. Brun, E.-J. Seo, Th. Efferth; Ancistectorine D, a naphthylisoquinoline alkaloid with antiprotozoal and antileukemic activities, and further 5,8'- and 7,1'-linked metabolites from the Chinese liana Ancistrocladus tectorius; Fitoterapia 2016, 115, 1-8.

    704)

    G. Bringmann, A. Irmer, T. Büttner, A. Schaumlöffel, G. Zhang, R. Seupel, D. Feineis, K. Fester; Axially Chiral Dimeric Naphthalene and Naphthoquinone Metabolites, from Root Cultures of the West African Liana Triphyophyllum peltatum; J. Nat. Prod. 2016, 79, 2094-2103.

    703)

    S.K. Bose, S. Brand, H. Oluwatola Omoregie, M. Haehnel, J. Maier, G. Bringmann, T.B. Marder; Highly Efficient Synthesis of Alkylboronate Esters via Cu(II)-Catalyzed Borylation of Unactivated Alkyl Bromides and Chlorides in Air; ACS Catalysis 2016, 6, 8332-8335.

    702)

    W. Li, L. Shen, T. Bruhn, P. Pedpradab, J. Wu, G. Bringmann; Trangmolins A-F with an Unprecedented Structural Plasticity of the Rings A and B: New Insight Into Limonoid BiosynthesisChem. Eur. J. 2016, 22, 11719-11727.

    701)

    G. Bringmann, M. Xu, R. Seupel, D. Feineis, J. Wu; Ancistrotectoquinones A and B, the First Quinoid Naphthylisoquinoline Alkaloids, from the Chinese Liana Ancistrocladus tectorius; Nat. Prod. Commun. 2016, 11, 971-976.

    700)

    G. Bringmann, N. Manchala, T. Büttner, B. Hertlein-Amslinger, R. Seupel; First Atroposelective total Synthesis of Enantiomerically Pure Ancistrocladidine and Ancistrotectorine; Chem. Eur. J. 2016, 22, 9792-9796.

    699)

    G. Bringmann, C. Steinert, D. Feineis, V. Mudogo, J. Betzin, C. Scheller; HIV-inhibitory michellamine-type dimeric naphthylisoquinoline alkaloids from the Central African liana Ancistrocladus congolensis; Phytochemistry 2016, 128, 71-81.

    698)G. Bringmann, A. Irmer, S. Rüdenauer, J. Mutanyatta-Comar, R. Seupel, D. Feineis; 5'-O-Methyldioncophylline D, a 7,8'-coupled naphthylisoquinoline alkaloid from callus cultures of Triphyophyllum peltatum, and its biosynthesis from a late-stage tetrahydroisoquinoline precursor; Tetrahedron 2016, 72, 2906-2912.
    697)G. Bringmann; Sorbicillacton A - eine chemische Schnitzeljagd; in Naturstoff-Forschung, Vorbild Natur (Ed. DECHEMA e.V.), Frankfurt, 2016, App "Naturstoff-Forschung" in App Store or Google Play.
    696)D. T. Tshitenge, K. Ndjoko Ioset, J. N. Lami, J. Ndelo-di-Phanzu, J.-P. Koy Sita Mufusama, G. Bringmann; Rational quality assessment procedure for less-investigated herbal medicines: case of a Congolese antimalarial drug with an analytical report; Fitoterapia 2016, 110, 189-195.
    695)E. Sawatzky, S. Wehle, B. Kling, J. Wendrich, G. Brinmgann, C. Sotriffer, J. Heilmann, M. Decker; Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode; J. Med. Chem. 2016, 59, 2067-2082.
    694)A. C. Gehrold, T. Bruhn, G. Bringmann; Axial, Helical, and Planar Chirality in Directly Linked Basket-Handle Porphyrin Arrays; J. Org. Chem. 2016, 81, 1075-1088.

    2015

    693)A. C. Gehrold, T. Bruhn, H. Schneider, U. Radius, D. Schmidt, G. Bringmann; Monomeric Chiral and Achiral Basket-Handle Porphyrins: Synthesis, Structural Features, and Arrested Tautomerism; J. Org. Chem. 2015, 80, 12359-12378.
    692)D. C. G. Götz, A. C. Gehrold, S. J. Dorazio, P. Daddario, L. Samankumara, G. Bringmann, C. Brückner, T. Bruhn; Indaphyrins and Indachlorins: Optical and Chiroptical Properties of a Family of Helimeric Porphyrinoids; Eur. J. Org. Chem. 2015, 18, 3913-3922.
    691)M. Hans, M. Charpentier, V. Huch, J. Jauch, T. Bruhn, G. Bringmann, D. Quandt; Stereoisomeric Composition of Natural Myrtucommulone A; J. Nat. Prod. 2015, 78, 2381-2389.
    690)W. Li, Z. Jiang, L. Shen, P. Pedpradab, T. Bruhn, J. Wu, G. Bringmann; Antiviral Limonoids Including Khayanolides from the Trang Mangrove Plant Xylocarpus moluccensis; J. Nat. Prod. 2015, 78, 1570–1578.
    689)Y. Hemberger, G. Zhang, R. Brun, M. Kaiser, G. Bringmann; Highly Antiplasmodial Non-Natural Oxidative Products of Dioncophylline A: Synthesis, Absolute Configuration, and Conformational Stability; Chem. Eur. J. 2015, 21, 14507-14518.
    688)M.D. Lewis, J. Behrends, C. Sá e Cunha, A.M. Mendes, F. Lasitschka, J.M. Sattler, K. Heiss, T.W.A. Kooij, M. Prudêncio, G. Bringmann, F. Frischknecht, A.-K. Müller; Chemical Attenuation of Plasmodium in the Liver Modulates Severe Malaria Disease Progression; J. Immunol. 2015, 194, 4860-4870.
    687)A. C. Gehrold, T. Bruhn, H. Schneider, U. Radius, G. Bringmann; Chiral and Achiral Basket-Handle Porphyrins: Short Synthesis and Stereostructures of These Versatile Building Blocks; Org. Lett. 2015, 17, 210-213.
    686) A. Ponte-Sucre, H. Bruhn, T. Schirmeister, A. Cecil, C. R. Albert, C. Buechold, M. Tischer, S. Schlesinger, T. Goebel, A. Fuss, D. Mathein, B. Merget, C. A. Sotriffer, A. Stich, G. Krohne, M. Engstler, G. Bringmann, U. Holzgrabe; Anti-trypanosomal activities and structural chemical properties of selected compound classes; Parasitol. Res. 2015, 114, 501-512.
    685)A. Cecil, K. Ohlsen, T. Menzel, P. Francois, J. Schrenzel, A. Fischer, K. Doerries, M. Selle, M. Lalk, J. Hantzschmann, M. Dittrich, C. Liang, J. Bernhardt, T. A. Oelschlaeger, G. Bringmann, H. Bruhn, M. Unger, A. Ponte-Sucre, L. Lehmann, T. Dandekar; Modelling antibiotic and cytotoxic isoquinoline effects in Staphylococcus aureus, Staphylococcus epidermidis and mammalian cells; Int. J. Med. Microbiol. 2015, 305, 96-109.

    2014

    684)T. Bruhn, G. Pescitelli, S. Jurinovich, A. Schaumlöffel, F. Witterauf, J. Ahrens, M. Bröring, G. Bringmann; Axially Chiral BODIPY DYEmers: An Apparent Exception to the Exciton Chirality Rule; Angew. Chem., Int. Ed. 2014, 53, 14592-14595; Axial-chirale BODIPY-DYEmers: eine offensichtliche Ausnahme für die Exciton-Chiralitäts-Methode; Angew. Chem. 2014, 126, 14821-14824.
    683)A. Kunz, A. Labes, J. Wiese, T. Bruhn, G. Bringmann, J. Imhoff; Nature’s Lab for Derivatization: New and Revised Structures of a Variety of Streptophenazines Produced by a Sponge-Derived Streptomyces Strain; Mar. Drugs 2014, 12, 1699-1714.
    682) T. Bruhn, F. Witterauf, D. C. G. Götz, C. T. Grimmer, M. Würtemberger, U. Radius, G. Bringmann; C,C- and N,C-Coupled Dimers of 2-Aminotetraphenylporphyrins: Regiocontrolled Synthesis, Spectroscopic Properties, and Quantum-Chemical Calculations; Chem. Eur. J. 2014, 20, 3998-4006.
    681)H. Wang, M.-Y. Li, F. Z. Katele, T. Satyanandamurty, J. Wu, G. Bringmann; Decandrinin, an unprecedented C9-spiro-fused 7,8-seco-ent-abietane from the Godavari mangrove Ceriops decandra; Beilstein J. Org. Chem. 2014, 10, 276-281.
    680)F. Turini, C. Steinert, G. Heubl, G. Bringmann, B. Kimbadi Lombe, V. Mudogo, H. Meimberg; Microsatellites facilitate species delimitation in Congolese Ancistrocladus (Ancistrocladaceae), a genus with pharmacologically potent naphthylisoquinoline alkaloids; Taxon 2014, 63, 329-341.

    2013

    679)J. Li, M.-Y. Li, T. Bruhn, F. Z. Katele, Q. Xiao, P. Pedpradab, J. Wu, G. Bringmann; Thaixylomolins A–C: Limonoids Featuring Two New Motifs from the Thai Xylocarpus moluccensis; Org. Lett. 2013, 15, 3682–3685.
    678)P. Jetter, C. Steinert, M. Knauer, G. Zhang, T. Bruhn, J. Wiese, J. F. Imhoff, H.-P. Fiedler, G. Bringmann; New bhimamycins from Streptomyces sp. AK 671; J. Antibiot. 2013, published online, DOI:10.1038/ja.2013.82.
    677)Y. Hemberger, J. Xu, V. Wray, P. Proksch,  J. Wu, G. Bringmann; Pestalotiopens A and B: Stereochemically Challenging Flexible Sesquiterpene-Cyclopaldic Acid Hybrids from Pestalotiopsis sp.; Chem. Eur. J. 2013, 19, 15556-15564.
    676)G. Bringmann, B. K. Lombe, C. Steinert, K. N. Ioset, R. Brun, F. Turini, G. Heubl, V. Mudogo; Mbandakamines A and B, Unsymmetrically Coupled Dimeric Naphthylisoquinoline Alkaloids, from a Congolese Ancistrocladus Species; Org. Lett. 2013, 15, 2590-2593.
    675)M. Lödige, M. D. Lewis, E. S. Paulsen, H. L. Esch, G. Pradel, L. Lehmann, R. Brun, G. Bringmann, A.-K. Mueller; A primaquine–chloroquine hybrid with dual activity against Plasmodium liver and blood stages; Int. J. Med. Microbiol. 2013, 303, 539-547.
    674)M. Baunach, L. Ding, T. Bruhn, G. Bringmann, C. Hertweck; Regiodivergent N-C and N-N Aryl Coupling Reactions of Indoloterpenes and Cycloether Formation Mediated by a Single Bacterial Flavoenzyme; Angew. Chem. 2013, 125, 9210-9213; Angew. Chem. Int. Ed. 2013, 52, 9040-9043.
    673)G. Bringmann, D. Hager, A. Schaumlöffel, M. Groh, A. Speicher; Enantiopure isoplagiochin C by directed deracemization through axis-to-axis chirality transfer; Tetrahedron: Asymmetry 2013, 24, 575-581.
    672)N. Jansen, B. Ohlendorf, A. Erhard, T. Bruhn, G. Bringmann, J.F. Imhoff; Helicusin E, Isochromophilone X and Isochromophilone XI: new chloroazaphilones produced by the fungus Bartalinia robillardoides strain LF550; Marine Drugs 2013, 11, 800-816.
    671)L. K. Blusch, Y. Hemberger, K. Pröpper, B. Dittrich, F. Witterauf, M. John, G. Bringmann, C. Brückner, F. Meyer; Siamese-Twin Porphyrin: A Pyrazole-Based Expanded Porphyrin of Persistent Helical Conformation (VIP and Cover); Chem. Eur. J. 2013, 19, 5868–5880.
    670) G. Bringmann, K. Thomale, S. Bischof, C. Schneider, M. Schultheis, T. Schwarz, H. Moll, U. Schurigt; A Novel Leishmania major Amastigote Assay in 96-Well Format for Rapid Drug Screening and its Use for the Discovery of a New Class of Leishmanicidal Quinolinium Salts; Antimicrob. Agents Chemother. 2013, 57, 3003-3011. 
    669)E.C. Tatsis, A. Schaumlöffel, A.C. Warskulat, G. Massiot, B. Schneider, G. Bringmann; Nudicaulins, Yellow Flower Pigments of Papaver nudicaule: Revised Constitution and Assignment of Absolute Configuration; Org. Lett. 2013, 15, 156-159.
    668)F. Koch, M. Kullmann, U. Selig, P. Nuernberger, D.C.G. Goetz, G. Bringmann, T. Brixner; Coherent two-dimensional electronic spectroscopy in the Soret band of a chiral porphyrin dimer; New J. Phys. 2013, 15, 025006 (DOI:10.1088/1367-2630/15/2/025006).
    667)T. Bruhn, Y. Hemberger, A. Schaumlöffel, G. Bringmann; SpecDis: Quantifying the Comparison of Calculated and Experimental Electronic Circular Dichroism Spectra; Chirality 2013, 25, 243-249.
    666)G. Bringmann, G. Zhang, T. Ölschläger, A. Stich, J. Wu, M. Chatterjee, R. Brun; Highly Selective Antiplasmodial Naphthylisoquinoline Alkaloids from Ancistrocladus tectorius; Phytochemistry 2013, 91, 220-228.
    665) G. Bringmann, G. Zhang, T. Büttner, G. Bauckmann, T. Kupfer, H. Braunschweig, R. Brun, V. Mudogo; Jozimine A2: The First Dimeric Dioncophyllaceae-Type Naphthylisoquinoline Alkaloid, with Three Chiral Axes and High Antiplasmodial Activity; Chem. Eur. J, 2013, 19, 916-923.

    2012

    664) M. Groh, D. Meidlinger, G. Bringmann, A. Speicher; Atroposelective Heck Macrocyclization: Enantioselective Synthesis of Bis(bibenzylic) Natural Products; Org. Lett., 2012, 14 , 4548–4551.
    663) A. Goel, A. Kumar, Y. Hemberger, A. Raghuvanshi, R. Jeet, G. Tiwari, M. Knauer, J. Kureel, A. K. Singh, A. Gautam, R. Trivedi, D. Singh, G. Bringmann; Synthesis, optical resolution, absolute configuration, and osteogenic activity of cis-pterocarpans; Org. Biomol. Chem., 2012, 10, 9583-9592.
    662)

     

    A. Schaumlöffel, M. Groh, A. Speicher, G. Bringmann; Stereochemical Assignment of Cyclic Bisbibenzyl by HPLC-CD on a Chiral Phase and Quantum-Chemical CD Calculations; Eur. J. Org. Chem. 2012, 6878-6887.
    661)J. Li, M.-Y. Li, T. Bruhn, D. C.G. Götz, Q. Xiao, T. Satyanandamurty, J. Wu, G. Bringmann; Andhraxylocarpins A-E: Structurally Intriguing Limonoids from Mangroves, Xylocarpus granatum and Xylocarpus moluccensis, Collected in the Estuaries of Andhra Pradesh; Chem. Eur. J., 2012, 18, 14342–14351.
    660)

    C. Almeida, Y. Hemberger, S. Bouhired, L. Natesan, S. Kehraus, K. Dimas, M. Gütschow, G. Bringmann, G.M. König; Marilines A-D, Novel Phthalimidines from the Sponge-Derived Fungus Stachylidium sp.; Chem. Eur. J. 2012, 18, 8827-8834.

    659)

    M. Kullmann, A. Hipke, P. Nuernberger, T. Bruhn, D. C.G. Goetz, M. Sekita, D.M. Guldi, G. Bringmann, T. Brixner; Ultrafast exciton dynamics after Soret- or Q-band excitation of a directly ß,ß'-linked bisporphyrin; PhysChemChemPhys 2012, 14, 8038-8050. ("Themed Issue on Ultrafast Chemical Dynamics")

    658)

    B. Messi, K. Ndjoko Ioset, B. Hertlein-Amslinger, G. Bringmann, A.M. Lannang, A.E. Nkengfack, J.-L. Wolfender, K. Hostettmann, G. Bringmann; Preussianone, a New Flavanone-Chromone Biflavonoid from Garcinia preussii Engl.; Molecules 2012, 17, 6114-6125.

    657)

    U.R. Abdelmohsen, A. Philippe, G. Zhang, W. Schmitz, S.M. Pimentel- Elardo, B. Hertlein-Amslinger, U. Hentschel, G. Bringmann; Cyclodysidins A-D, cyclic lipopeptides from the marine sponge-derived Streptomyces strain RV15; Tetrahedron Lett. 2012, 53, 23-29.

    656)

    G. Bringmann, D. Goetz T. Bruhn; The Online Stereoanalysis of Chiral Compounds by HPLC-ECD Coupling in Combination with Quantum-Chemical Calculations; in Comprehensive Chiroptical Spectroscopy (N. Berova, P. Polavarapu, K. Nakanishi, R.W. Woody, Eds.), Vol. 2, John Wiley & Sons, 2012, pp. 355-386.

    2011

    655)

    S. M. Pimentel-Elardo, V. Buback, T. A. M. Gulder, T. S. Bugni, J. Reppart, G. Bringmann, C. M. Ireland, T. Schirmeister, U. Hentschel; New Tetromycin Derivatives with Anti-Trypanosomal and Protease Inhibitory Activities; Mar. Drugs 2011, 9, 1682-1697.

     

    654)

    S. Loesgen, T. Bruhn, G. Bringmann, K. Meindl, I. Dix, B. Schulz, A. Zeeck; (+)-Flavipucine, the Missing Member of the Pyridione Epoxide Family of Fungal Antibiotics; Eur. J. Org. Chem. 2011, 5156–5162.

     

    653)

    C. Brückner, D.C.G. Götz, S.P. Fox, C. Ryppa, J.R. McCarthy, T. Bruhn, H.W. Daniell, S. Banerjee, P. Daddario, M. Zeller, R.W. Boyle, G. Bringmann; Helimeric Porphyrinoids: Stereostructure and Chiral Resolution of meso-Tetraarylmorpholinochlorins; J. Am. Chem. Soc. 2011, 133, 8740-8752.

     

    652)  

    A. Cecil, C. Rikanovic, K. Ohlsen, C. Liang, T. Ölschläger, T. Gulder, G. Bringmann, U. Holzgrabe, M. Unger, T. Dandekar; Modelling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in S. aureus, S. epidermidis and human cells; Genome Biol. 2011, 12, R24, open access.

     

    651)  

    A. Goel, D. Verma, R. Pratap, G. Taneja, Y. Hemberger, M. Knauer, R. Raghunandan, P.R. Maulik, V.J. Ram, G. Bringmann; Partially Hydrogenated 8- Oxa[5]helicenes and [5]Helicenes – Synthesis, Structure, and Dynamics; Eur. J. Org. Chem. 2011, 2940-2947.

     

    650)  

    H. Frank, L. Campanella, F. Dondi, E. Leitner, J. Mehlich, G. Rossi, K. Ndjoko, G. Bringmann; Ethics, Chemistry and Education for the Environment; Angew. Chem. 2011, 123. 8632-8641; Angew. Chem. Int. Ed. 2011, 50, 8445-8458.

     

    649)

    G. Bergner, C. Albert, M. Schilling, G. Bringmann, T. Schirmeister, B. Dietzek, S. Schlücker, J. Popp; Quantitative CARS microscopy and Raman microspectroscopy of C-deuterated drugs;
    Analyst 2011, 136, 3686-369.

     

    648)E. Kugelmann, C.R. Albert, G. Bringmann, U. Holzgrabe; Fenton‘s oxidation: a tool for the investigation of potential drug metabolites; J. Pharm. Biomed. Anal. 2011, 54, 1047-1058.

     

    647) 

    G. Bringmann, T.A.M. Gulder, T. Gulder; Asymmetric Synthesis of (M)- 2-Hydroxymethyl-1(2-Hydroxy-4,6- dimethylphenyl)naphthalene via a Configurationally Unstable Biaryl Lactone; Org. Synth. 2011, 88, 70-78.

     

    646) 

    L. Liu, T. Bruhn, L. Guo, D. C. G. Götz, R. Brun, A. Stich, Y. Che, G. Bringmann; Chloropupukeanolides C–E, Cytotoxic Pupukeanane Chlorides with a Spiroketal Skeleton from Pestalotiopsis fici; Chem. Eur. J. 2011, 17, 2604-2613 (with Cover Picture).

     

    645)

    G. Bringmann, D. Wunderlich; Sorbicillactone A – a Chemical Paper Chase; in Inspired by Nature - State and Perspektives of Natural Products Research in Germany (Eds. G. Bringmann, S. Grabley, J. Piel, D. Sell, T. Spellig, C. Steinbach), DECHEMA e.V., Frankfurt; 2011, 36-43.

     

    644)G. Bringmann, G. Zhang. A. Hager, M. Moos, A. Irmer, R. Bargou, M. Chatterjee; Antitumoral activities of dioncoquinones B and C and related naphthoquinones gained from total synthesis or isolation from plants; Eur. J. Med. Chem. 2011, 46, 5778-5789.
    643)E.M. Finnigan, R. Rein, N. Solladié, K. Dahms, D.C.G. Götz, G. Bringmann, M.O. Senge; Synthesis and ligand binding properties of triptycene-linked porphyrin arrays; Tetrahedron 2011, 67, 1126-1134.

     

    642)  

    L. Du, J. Ai, D. Li, T. Zhu, Y. Wang, M. Knauer, T. Bruhn, H. Liu,  M. Geng, Q. Gu, G. Bringmann; Aspergiolides C and D: Spirocyclic Aromatic Polyketides with Potent Protein Kinase c-Met Inhibitory Effects; Chem. Eur. J. 2011, 17, 1319–1326.

     

    641)

    C. Büchold, Y. Hemberger, C. Heindl, A. Welker, B. Degel, T. Pfeuffer, P. Staib, S. Schneider, P. J. Rosenthal, J. Gut, J. Morschhäuser, G. Bringmann, T. Schirmeister; New cis-Configured Aziridine-2-carboxylates as Aspartic Acid Protease Inhibitors; ChemMedChem 2011, 6, 141–152.

     

    640)G. Bringmann, T. Gulder, T. A. M. Gulder, M. Breuning; Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products; Chem. Rev. 2011, 111, 563-639.

     

    639)  

    G. Bringmann, B. Hertlein-Amslinger, I. Kajahn, M. Dreyer,R. Brun, H. Moll, A. Stich, K. Ndjoko Ioset, W. Schmitz, L. Ngoc; Phenolic analogs of the N,C-coupled naphthylisoquinoline alkaloid ancistrocladinium A, from Ancistrocladus cochinchinensis, (Ancistrocladaceae), with improved antiprotozoal activities; Phytochemistry 2011, 72, 89-93.

     

    638)K. Gebhardt, S.W. Meyer, J. Schinko, A. Zeeck, G. Bringmann, H.-P. Fiedler; Phenalinolactones A–D, novel terpenoglycoside antibiotics from Streptomyces sp. Tü 6071; J. Antibiot. 2011, 64, 229-232.

     

    2010

    637)C.A. Schmidt, R. Murillo, T. Bruhn, G. Bringmann, M. Goettert, B. Heinzmann, V. Brecht, S. Laufer, I. Merfort; Catechin Derivatives from Parapiptadenia rigida with in vitro Wound-Healing Properties; J. Nat. Prod. 2010, 73, 2035–2041.

     

    636)*  G. Bringmann , M. Lödige , A.-K. Müller , M. Lewis , G. Pradel , H. Moll , U. Schurigt , L. Lehmann , R. Brun ; Hybridverbindungen aus 4- und 8-Aminochinolinen zur prophylaktischen und therapeutischen Behandlung von Malaria und anderen parasitären Erkrankungen; German Patent Application (DE ), filed 14.10.0210.

     

    635)  G. Bringmann, G. Lang, T. Bruhn, K. Schäffler, S. Steffens, R. Schmaljohann, J. Wiese, J. F. Imhoff; Sorbifuranones A-C, Sorbicillinoid Metabolites From Penicillium Strains Isolated From Mediterranean Sponges,Tetrahedron 2010, 66, 9894-9901.

     

    634)*

    G. Bringmann , M. Lödige , A. Kronhardt , C. Beitzinger , H. Barth , R. Benz ; Aminoquinolinium Salts; European Patent Application (DE ), filed 29.09.2010.

     

    633) 

    A. Jindaprasert, S. Samappito, K. Springob, J. Schmidt, T. Gulder, W. De-Eknamkul, G. Bringmann, T.M. Kutchan; In Vitro Plants, Callus and Root Cultures of Plumbago indica and Their Biosynthetic Potential for Plumbagin;
    King Mongkut’s Agro-Ind. J. 2010, 2, 53-65.

     

    632) 

    G. Fan, Z. Li, Y. Zeng, M. Xu, Z. Deng, T. Bruhn, H. Bruhn, J. Morschhäuser, G. Bringmann, W. Lin; Baculiferins A-O, O-Sulfated Pyrrole Alkaloids with anti-HIV-1 Activity, from the Chinese Marine Sponge Iotrochota baculifera;
    Bioorg. Med. Chem. 2010, 18, 5466–5474.

     

    631)

    G. Bringmann, S. K. Bischof, S. Müller, T. Gulder, C. Winter, A. Stich, H. Moll, M. Kaiser, R. Brun, J. Dreher, K. Baumann; QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids; Eur. J. Med. Chem. 2010, 45,  5370-5383.

     

    630) 

    G. Bringmann, T. Gulder, B. Hertlein, Y. Hemberger, F. Meyer; Total Synthesis of the N,C-Coupled Naphthylisoquinoline Alkaloids Ancistrocladinium A and B, and Related Analogues; J. Am. Chem. Soc. 2010, 132, 1151-1158.

     

    629) 

    A. Hansjakob, S. Bischof, G. Bringmann, M. Riederer, U. Hildebrand; Very-long chain aldehydes promote in vitro prepenetration processes of Blumeria graminis in a dose and chain-length dependent manner; New Phytologist 2010, 188, 1039-1054.

     

    628) 

    M. Xu, T. Bruhn, B. Hertlein, R. Brun, A. Stich, J. Wu, G. Bringmann; Shuangancistrotectorines A-E, Dimeric Naphthylisoquinoline Alkaloids with Three Chiral Biaryl Axes, from the Chinese Plant Ancistrocladus tectorius; Chem. Eur. J. 2010, 16, 4206-4216 (with cover picture).

     

    627)  

    H. Meimberg, H. Rischer, F. Turini, V. Chamchumroon, M. Dreyer, M. Sommaro, G. Bringmann, G. Heubl; Evidence for species differentiation within the Ancistrocladus tectorius complex (Ancistrocladaceae) in Southeast Asia: A molecular approach; Plant Syst. Evol. 2010, 284, 77-98.

     

    626)  

    G. Heubl, F. Turini, V. Mudogo, I. Kajahn, G. Bringmann; Ancistrocladus ileboensis (D.R.Congo), a new liana with unique alkaloids; Pl. Ecol. Evol. 2010, 143, 63-69.

     

    625)  

    K. Rembold, S. Poppinga, O. Kriesten, A. Irmer, H. Rischer, G. Bringmann; Triphyophyllum peltatum (Dioncophyllaceae) an Observations on its Carnivory; Carniv. Pl. Newslett. 2010, 39, 71-77 (with cover picture).

     

    624)  

    U. Hentschel, G. Bringmann; Marine Schwämme - Füllhorne der Meere; Pharmazie uns. Zeit 2010, 39, 62-66.

     

    623)  

    A. Ponte-Sucre, T. Gulder, T.A.M. Gulder, G. Vollmers, G. Bringmann, H. Moll; Alterations to the structure of Leishmania major induced by N-arylisoquinolines correlate with compound accumulation and disposition; J. Med.  Microbiol. 2010, 59, 69-75. (with cover picture)

     

    622)

    J. Moldenhauer, D.C.G. Götz, C.R. Albert, S.K. Bischof, K. Schneider, R.D. Süssmuth, M. Engeser, H. Gross, G. Bringmann, J. Piel; The Final Steps of Bacillaene Biosynthesis in Bacillus amyloliquefaciens FZB42: Direct Evidence for beta,gamma-Dehydration by a trans- AT Polyketide Synthase; Angew. Chem. 2010, 122, 1507 - 1509; Angew. Chem. Int. Ed. 2010, 49, 1465-1467.

     

     

     

    2009

    621)  D.C.G. Götz, T. Bruhn, O. Senge, G. Bringmann; Synthesis and Stereochemical Characterization of Highly Unsymmetric ß,meso-Linked Porphyrin Arrays; J. Org. Chem. 2009, 74, 8005–8020. (‚Featured Article’, with cover picture).
    620)  G. Bringmann, A. Irmer, D. Feineis, T.A.M. Gulder, H.- P. Fiedler; Convergence in the Biosynthesis of Polyketide-Derived Natural Products from Plants, Fungi, and Bacteria; Phytochemistry (special issue ‚Evolution of Metabolic Diversity’) 2009, 70, 1776-1786.
    619)  A. Speicher, M. Groh, J. Zapp, A. Schaumlöffel, M. Knauer, G. Bringmann; A Synthesis-Driven Structure Revision of „Plagiochin E“, a Highly Bioactive Bisbibenzyls; Synlett 2009, 1852-1858.
    618)  G. Bringmann, K. Maksimenka, T. Bruhn, M. Reichert, T. Harada, R. Kuroda; Quantum chemical CD calculations of dioncophylline A in the solid state;Tetrahedron 2009, 65, 5720-5728.
    617)  F. Tribl, E. Asan, T. Arzberger, T. Tatschner, E. Langenfeld, H.E. Meyer, G. Bringmann, P. Riederer, M. Gerlach, K. Markus; Identification of L-ferritin in neuromelanin granules of the human substantia nigra – a targeted proteomics approach; Mol. Cell. Proteomics 2009, 8, 1832-1838.
    616)   J. Bunzen, T. Bruhn, G. Bringmann, A. Lützen; Synthesis and Helicate Formation of a New Family of BINOL-Based Bis(bipyridine) Ligands; J. Am. Chem. Soc. 2009, 131, 3621–3630.

     

    615)  

    G. Bringmann, T. Bruhn, K. Maksimenka, Y. Hemberger; The Assignment of Absolute Stereostructures by Quantum Chemical Circular Dichroism Calculations; Eur. J. Org. Chem. 2009,  2717 - 2727.

    614)  

    A. Ponte-Sucre, T. Gulder, A. Wegehaupt, C. Albert, C. Rikanovic, L. Schaeflein, A. Frank, M. Schultheis, M. Unger, U. Holzgrabe, G. Bringmann, H. Moll; Structure- Activity Relationship and Studies on the Molecular Mechanism of Leishmanicidal N,C-Coupled Arylisoquinolinium Salts; J. Med. Chem. 2009, 52, 626–636.

    613)  T.S. Balaban, A.D. Bhise, G. Bringmann, J. Bürck, C. Chappaz-Gillot, A. Eichhöfer, D. Fenske, D. Götz, M. Knauer, T. Mizoguchi, D. Mössinger, M. Reichert, H. Roesner, C. Roussel, M. Schraut, H. Tamiaki, N. Vanthuyne; Mimics of the self-assembling chlorosomal bacteriochlorophylls: Regio- and stereoselective synthesis and stereoanalysis of acyl-(1- hydroxyalkyl)porphyrinsJ. Am. Chem. Soc. 2009, 131, 14480–14492.
    612)  G. Bringmann, T.A.M. Gulder, A. Hamm, M. Goodfellow, H.-P. Fiedler; Multiple convergence in polyketide biosynthesis: a third folding mode to the anthraquinone chrysophanol, involving a bicyclic diketone; Chem. Commun. 2009, 6810-6812.
    611) 

    Z. Yunt, K. Reinhardt, A. Li, M. Engeser, H.-M. Dahse, M. Gütschow, T. Bruhn, G. Bringmann, J. Piel; Cleavage of Four Carbon-Carbon Bonds during Biosynthesis of the Griseorhodin A Spiroketal Pharmacophore; J. Am. Chem. Soc. 2009131, 2297-2305.

     

    2008

    610)

    G. Bringmann, D.C.G. Götz, T.A.M. Gulder, T.H. Gehrke, T. Bruhn, T, Kupfer, K. Radacki, H. Braunschweig, A. Heckmann, C. Lambert; Axially Chiral ß,ß’-Bisporphyrins: Synthesis and Configurational Stability Tuned by the Central Metals; J. Am. Chem. Soc. 2008, 130, 17812–17825.

     

    609)

    S. M. Pimentel-Elardo, T.A.M. Gulder, U. Hentschel, G. Bringmann; Cebulactams A1 and A2, new macrolactams isolated from Saccharopolyspora cebuensis, the first obligate marine strain of the genus Saccharopolyspora; Tetrahedron Lett. 2008, 49, 6889-6892.

     

    608)

    K.F. Schwedhelm, M. Horstmann, J.H. Faber, Y. Reichert, M. Büchner, G. Bringmann, C. Faber; Spin state of chloroquine-heme complexes: formation of a hemin tetramer adduct; Open Spectrosc. J. 2008, 2, 10-18.

    607)

    G. Bringmann, S. Rüdenauer, A. Irmer, T. Bruhn, R. Brun, T. Heimberger, T. Stühmer, R. Bargou, M. Chatterjee; Antitumoral Dioncoquinones and Ancistroquinones from cell cultures of Triphyophyllum peltatum (Dioncophyllaceae) and Ancistrocladus abbreviatus (Ancistrocladaceae); Phytochemistry 2008, 69, 2501-2509.

     

    606)*

    G. Bringmann, S. Rüdenauer, A. Irmer, R. Brun, Chatterjee, R. Bargou; Dioncochinone, Ancistrochinone und davon abgeleitete Verbindungen, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE ), filed  06.02.2008.

     

    605)

    R. Deeken, P. Ache, I. Kajahn, C. J. Klinkenberg, G. Bringmann, R. Hedrich; Identification of Arabidopsis thaliana phloem RNAs provides a search criterion for phloem-based transcripts hidden in complex data sets of microarray experiments; Plant Journal 2008, 55, 746-759.

     

    604)

    G. Bringmann, S. Rüdenauer, T. Bruhn, L. Benson; Total synthesis of the antimalarial naphthylisoquinoline alkaloid 5-epi-4’-O-demethylancistrobertsonine C by asymmetric Suzuki cross coupling reaction; Tetrahedron 2008, 64, 5563-5568.

     

    603)

    G. Bringmann, A. Irmer; Acetogenic Anthraquinones: Biosynthetic Convergence and Chemical Evidence of Enzymatic Cooperation in Nature; Phytochem. Rev. 2008, 7, 499-511.

     

    602)

    G. Bringmann, T.A.M. Gulder, M. Reichert, T. Gulder; The Online Assignement of the Absolute Configuration of Natural Products: HPLC-CD in Combination with Quantum Chemical Calculations; Chirality 2008, 20, 628-642.

     

    601)

    U. Kiehne, T. Bruhn, G. Schnakenburg, R. Fröhlich, G. Bringmann, A. Lützen; Synthesis, resolution, and Absolute Configuration of Difunctionalized Tröger´s Base Derivatives; Chem. Eur. J. 2008, 14, 4246-4255.

     

    600)

    G. Bringmann, B. Abegaz, M. Knauer, J. Mutanyatta; Knipholone and related 4-phenylanthraquinones, a young class of structurally, pharmacologically, and biosynthetically intriguing natural products; Nat. Prod. Rep. 2008, 25, 696-718.

     

    599)

    G. Bringmann, J. Spuziak, J.H. Faber, T. Gulder, I. Kajahn, M. Dreyer, G. Heubl, R. Brun, V. Mudogo; Six naphthylisoquinoline alkaloids and a related benzopyranone from a Congolese Ancistrocladus species related to Ancistrocladus congolensis; Phytochemistry 2008, 69, 1065-1075.

     

    598)

    G. Bringmann, J. Mutanyatta-Comar, K. Maksimenka, J.M. Wanjohi, M. Heydenreich, R. Brun, W.E.G. Müller, M.G. Peter, J.O. Midiwo, A. Yenesew; Joziknipholones A and B, the first dimeric phenylanthracenes, from the roots of Bulbine frutescens; Chem. Eur. J. 2008, 14, 1420-1429.

     

    597)

    H.-P. Fiedler, A. Dieter, T.A.M. Gulder, I. Kajahn, A. Hamm, G. Payne, M. Goodfellow, W.E.G. Müller, G. Bringmann; Genoketides A1 and A2, new octaketides and biosynthetic intermediates of chrysophanol produced by Streptomyces sp. AK 671;
    J. Antibiot. 2008, 61, 464-473.

     

    596)

    J. Wu, S. Zhang, Q. Xiao, H. Ding, T. Bruhn, G. Bringmann; Xylogranatins F-R: Antifeedants from the Chinese Mangrove, Xylocarpus granatum, Suggesting a New Biogenetic Pathway to Tetranortriterpenoids; Chem. Eur. J. 2008, 14, 1129-1144.

     

    595) 

    G. Bringmann, R. Bruhn, M. Kaiser, S. Neumann; Synthesis and antiprotozoal activities of simplified analogs of naphthylisoquinoline alkaloids; Eur. J. Med. Chem.2008, 43, 32-34.

     

    594)

    G. Bringmann, M. Reichert, Y. Hemberger; The absolute configuration of streptonigrin; Tetrahedron 2008, 64, 515-521.

     

    593)V. Zabka, U. Hildebrand, M. Stangl, G. Vogg, G. Bringmann, M. Riederer; The wax effect: pre-prenetration process of powdery mildew affected by host surface properties; New Phytologist 2008, 177, 215-263.

    2007

    592)

    A. Goel, F.V. Singh, V. Kumar, M. Reichert, T.A.M. Gulder, G. Bringmann; Synthesis, Optical Resolution, and Configurational Assignment of Novel Axially Chiral Quateraryls; J. Org. Chem. 2007, 72, 7765-7768.

     

    591)

    G. Bringmann, Y. Haagen, T. Gulder, T. Gulder, L. Heide; Biosynthesis of the isoprenoid moieties of furanonaphtoquinone I and Endophenazine A in Streptomyces cinnamonensis DSM 1042; J. Org. Chem. 2007, 72, 4198-4204.

    590)

    G. Bringmann, K. Maksimenka, J. Mutanyatta-Comar, M. Knauer, T. Bruhn; The absolute axial configurations of knipholone and knipholone anthrone by TDDFT and DFT/MRCI CD calculations: a revision;Tetrahedron 2007, 63, 9810-9824.

    589)

    P. Osswald, M. Reichert, G. Bringmann, F. Würthner; Perylene Bisimide Atropisomers – Synthesis, Resolution and Stereochemical Assignment; J. Org. Chem. 2007, 72, 3403-3411.

     

    588)

    G. Bringmann, T.A.M. Gulder, G. Lang, S. Schmitt, R. Stöhr, J. Wiese, K. Nagel, J.F. Imhoff; Large-Scale Biotechnological Production of the  Antileukemic Marine Natrual Product Sorbicillactone A; Marine Drugs 2007, 5, 23-30.

     

    587)

    A. Charchoglyan, A. Abrahamyan, I. Fujii, Z. Boubakir, T.A.M. Gulder, T.M. Kutchan,H. Vardapetyan,  G. Bringmann, Y. Ebizuka, L. Beerhues; Differential accumulation of hyperforin and secohyperforin in Hypericum perforatum tissue cultures; Phytochemistry 2007, 68, 2670-2677.

    586)

    X. Yang, T.A.M. Gulder, M. Reichert, C. Tang, C. Ke, Y. Ye, G. Bringmann; Parvistimenis A-D, a new type of dimeric phenylethyl benzoquinones from Stemona parviflora Wright; Tetrahedron, 2007, 63, 4688-4694.

     

    585)

    L.-F. Tietze, F. Major, I. Schuberth, D.A. Spiegl, B. Krewer, K. Maksimenka, G. Bringmann, J. Magull; Selective Treatment of Cancer: Synthesis, Biological Evaluation, and Structural Elucidation of Novel Analogues of the Antibiotic CC-1065 and the Duocarmycins; Chem. Eur. J. 2007, 13, 4396-4409.

    584)

    G. Bringmann, T. F. Noll, M. Dreyer, T. Gulder, M. Grüne, D. Moskau; Polyketide Folding in Higher Plants: Biosynthesis of the Phenylanthraquinone Knipholone; J. Org. Chem. 2007, 72, 3247-3252.

    583)

    G. Bringmann, C. M. Gampe, Y. Reichert, T. Bruhn, J.H. Faber, M. Mikyna, M. Reichert, M. Leippe, R. Brun, C. Gelhaus; Synthesis and Pharmacological Evaluation of Fluorescent and Photoactivatable Analogues of Antiplasmodial Naphthylisoquinolines; J. Med. Chem. 2007, 50, 6104-6115.

    582)

    K.F. Schwedhelm, M. Horstmann, J.H. Faber, Y. Reichert, G. Bringmann, C. Faber; The novel antimalarial compound dioncophylline C forms a complex with heme in solution; ChemMedChem 2007, 2, 541-548.

    581)

    M.C. Kozlowski, E.C. Dugan, E.S. DiVirgilio, K. Maksimenka G. Bringmann; Asymmetric Total Synthesis of Nigerone and ent-Nigerone: Enantioselective Oxidative Biaryl Coupling of Highly Hindered Naphthols; Adv. Synth. Catal. 2007, 349, 583-594.

    580)

    M. Xu, G. Gessner, I. Groth, C. Lange, A, Christner, T. Bruhn, Z. Deng, X. Li, S.H. Heinemann, S. Grabley, G. Bringmann, I. Sattler, W. Lin; Shearinines D-K, new indole triterpenoids from an endophytic Penicillium sp. (strain HKI0459) with blocking activity on large-conductance calcium-activated potassium channels; Tetrahedron 2007, 63, 435-444.

    579)

    G. Bringmann, J. Mutanyatta, M. Greb, S. Rüdenauer, T. Noll, A. Irmer; Biosynthesis of naphthylisoquinoline alkaloids: synthesis and incorporation of an advanced 13C2-labeled isoquinoline precursor; Tetrahedron 2007, 63, 1755-1761.

    578)

    C. Anderle, S. Alt, T. Gulder, G. Bringmann, B. Kammerer, B. Gust, L. Heide; Biosynthesis of clorobiocin: investigation of the transfer and methylation of the pyrrolyl-2-carboxyl moiety; Arch. Microbiol. 2007, 187, 227-237.

    577)

    T. Frosch, M. Schmitt, T. Noll, G. Bringmann, K. Schenzel, J. Popp; Ultrasensitive in situ Tracing of the Alkaloid Dioncophylline A in the Tropical Liana Triphyophyllum peltatum by Applying Deep-UV Resonance Raman Microscopy; Anal. Chem. 2007, 79, 986-993.

    576)

    G. Bringmann, D. Wunderlich; Sorbicillacton A - eine chemische Schnitzeljagd; in Vorbild Natur, Stand und perspektiven der Naturstoff-Forschung in Deutschland (Eds. G. Bringmann, S. Grabley, J. Piel, D. Sell, T. Spellig, C. Steinbach), DECHEMA e.V., Frankfurt; 2007, 36-43.

    575)

    T. Frosch, M. Schmitt, G. Bringmann, W. Kiefer, J. Popp; Structural Analysis of the Anti-Malaria Active Agent Chloroquine under Physiological Conditions; J. Phys. Chem. B 2007, 111, 1815-1822.

    574)

    A. Ponte-Sucre, J.H. Faber, T. Gulder, I. Kajahn, S.E.H. Pedersen, M. Schultheis, G. Bringmann, H. Moll; Activities of Naphthylisoquinoline Alkaloids and Synthetic Analogs against Leishmania major; Antimicrob. Agents Chemother. 2007, 51, 188-194.

     

    573) G. Bringmann, T. Gulder, T.A.M. Gulder; Asymmetric Synthesis of Biaryls by the ‘Lactone Method’ in Asymmetric Synthesis – The Essentials (Eds. M. Christmann, S. Bräse), Wiley-VCH, Weinheim; 2007, 246-250.

    2006

    572)

    J. Hartung, K. Daniel, C. Rummey, G. Bringmann; On the stereoselectivity of 4-penten-1-oxyl radical 5-exo-trig cyclizations; Org. Biomol. Chem. 2006, 4, 4089-4100.

    571)

    G. Bringmann, I. Kajahn, M. Reichert, S.E.H. Pedersen, J.H. Faber, T.Gulder, R. Brun, S.B. Christensen, A. Ponte-Sucre, H. Moll, G. Heubl, V. Mudogo; Ancistrocladinium A and B, the First N,C-Coupled Naphthyldihydroisoquinoline Alkaloids, from a Congolese Ancistrocladus Species; J. Org. Chem. 2006, 71, 9348-9356.

    570)

    G. Bringmann, T.F. Noll, T.A.M. Gulder, M. Grüne, M. Dreyer, C. Wilde, F. Pankewitz, M. Hilker, G.D. Payne, A.L. Jones, M. Goodfellow, H.-P. Fiedler; Different polyketide folding modes converge to an identical molecular architecture; Nature Chem. Biol. 2006, 2, 429-433.

    569)

    K. Ishida, K. Maksimenka , K. Fritzsche, K. Scherlach, G. Bringmann, C. Hertweck; The Boat-Shaped Polyketide Resistoflavin Results from Re-Facial Central Hydroxylation of the Discoid Metabolite Resistomycin; J. Am. Chem. Soc. 2006, 128, 14619-14624.

    568)

    G. Bringmann, S. Rüdenauer, D.C.G. Götz, T.A.M. Gulder, M. Reichert; Axially Chiral Directly ß,ß-Linked Bisporphyrins: Synthesis and Stereostructure; Org. Lett. 2006, 8, 4743-4746.

    567)

    D. Hölscher, M. Reichert, H. Görls, O. Ohlenschläger, G. Bringmann, B. Schneider; Monolaterol, the First Configurationally Assigned Phenylphenanolone Derivative with a Stereogenic Center at C-9, from Monocheria elata; J. Nat. Prod. 2006, 69, 1614-1617.

    566)

    A. Storch, Y.-I. Hwang, G. Bringmann, D. Feineis, S. Ott, R. Brückner, J. Schwarz; Cytotoxicity of chloral-derived ß-carbolines is not specific towards neuronal nor dopaminergic cells; J. Neural Transm. 2006, 113, 1895-1901.

    565)*

    G. Bringmann, T. Gulder, F. Meier, V. Mudogo, H. Moll, A. Ponte-Sucre, R. Brun, A. Stich, J. Morschhäuser, U. Hentschel, W. Ziebuhr; N,C-verknüpfte Naphthylisochinoline und deren Derivate; Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE ), filed 27.09.06; PCT/EP. Issued.

    564)

    F. Tribl, K. Marcus, G. Bringmann, H.E. Meyer, M. Gerlach, P. Riederer; Proteomics in the human brain: sub-proteomes might hold the key to handle brain complexity; J. Neural Transm. 2006, 113, 1041-1054.

    563)

    G. Bringmann, D. Feineis, M. Münchbach, R. God, K. Peters, E.-M. Peters, R. Mössner, K.-P. Lesch; Toxicity and Metabolism of the Chloral-Derived Mammalian Alkaloid 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo) in PC12 Cells; Z. Naturforsch. 2006, 61c, 601-610.

    562)

    P. Kapková, E. Heller, E. Kugelmann, J.H. Faber, G. Bringmann, U. Kessler, G. Folkers, U. Holzgrabe; Random Chemistry as a New Tool for the Generation of Small-Compound Libraries; Arch. Pharm. Chem. Life Sci.  2006, 339, 489-497.

    561)

    M. Sieber, W. Dekant, J.H. Faber, G. Bringmann; Biotransformation and pharmacokinetics of the antiplasmodial naphthylisoquinoline alkaloid dioncophylline A; Xenobiotica 2006, 36, 750-762.

    560)

    G. Bringmann, H. Scharl, K. Maksimenka, K. Radacki, H. Braunschweig, P. Wich, C. Schmuck; Atropodiastereoselective Cleavage of Configurationally Unstable Biaryl Lactones with Amino Acid Esters; Eur. J. Org. Chem. 2006, 4349-4361 (with cover picture).

    559)

    G. Bringmann, D. Feineis, R. Brückner, R. God, C. Grote, W. Wesemann; Synthesis of radiolabelled 1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo), a neurotoxic chloral-derived mammalian alkaloid, and its biodistribution in rats; Eur. J. Pharm. Sci. 2006, 28, 412-422.

    558)

    F. Tribl, K. Marcus, H.E. Meyer, G. Bringmann, M. Gerlach, P. Riederer; Subcellular proteomics reveals neuromelanin granules to be a lysosome-related organelle; J. Neural Transm. 2006, 113, 741-749.

    557)

    M. Scheuermayer, T.A.M. Gulder, G. Bringmann, U. Hentschel; Rubritalea marina gen. nov., sp. nov., a marine representative of the phylum ‘Verrucomicrobia’, isolated from a sponge (Porifera); Int. J. Syst. Evol. Microbiol. 2006, 56, 2119-2124.

    556)

    G. Bringmann, T. Gulder, M. Reichert, F. Meyer; Ancisheynine, the First N,C-Coupled Naphthylisoquinoline Alkaloid: Total Synthesis and Stereochemical Analysis; Org. Lett. 2006, 8, 1037-1040.

    555)

    T. Frosch, M. Schmitt, K. Schenzel, J.H. Faber, G. Bringmann, W. Kiefer, J. Popp; In Vivo Localization and Identification of the Antiplasmodial Alkaloid Dioncophylline A in the Tropical Liana Triphyophyllum peltatum by a Combination of Fluorescence, Near Infrared Fourier Transform Raman Microscopy, and Density Functional Theory Calculations; Biopolymers 2006, 82, 295-300.

    554)

    S. Cîntǎ-Pînzaru, N. Peica, B. Küstner, S. Schlücker, M. Schmitt, T. Frosch, J.H. Faber, G. Bringmann, J. Popp; FT-Raman and NIR-SERS characterization of the antimalarial drugs chloroquine and mefloquine and their interaction with hematin; J. Raman Spectrosc. 2006, 37, 326-334.

     

    553)

    G. Heubl, G. Bringmann, H. Meimberg; Molecular phylogeny and character evolution of carnivorous plant families in Caryophyllales - revisited; Plant Biol. 2006, 8, 821-830.

     

    552)

    K. Felgentreff, C. Beisswenger, M. Griese, T. Gulder, G. Bringmann, R. Bals; The antimicrobial peptide cathelicidin interacts with airway mucus; Peptides 2006, 27, 3100-3106.

    551)

    B. Sontag, M. Rüth, P. Spiteller, N. Arnold, W. Steglich, M. Reichert, G. Bringmann; Chromogenic Meroterpenoids from the Mushrooms Russula ochroleuca and R. viscida; Eur. J. Org. Chem. 2006, 1023-1033.

    2005

    550)

    J. Mutanyatta, M. Bezabih, B.M. Abegaz, M. Dreyer, R. Brun, N. Kocher, G. Bringmann; The First 6'-O-Sulfated Phenylanthraquinones: Isolation from Bulbine frutescens, Structural Elucidation, Enantiomeric Purity, and Partial Synthesis; Tetrahedron 2005, 61, 8475-8484 (with cover picture).

    549)

    B. Clark, R.J. Capon, E. Lacey, S. Tennant, J.H. Gill, B. Bulheller, G. Bringmann; Gymnoascolides A-C: Aromatic Butenolides from an Australian Isolate of the Soil Ascomycete Gymnoascus reessii; J. Nat. Prod. 2005, 68, 1226-1230.

    548)

    O. Guhling, C. Kinzler, M. Dreyer, G. Bringmann, R. Jetter; Chemical composition of ant-plants: cuticular wax and glandular trichomes on leaves of Macaranga tanarius (Euphorbiaceae); J. Chem. Ecol. 2005, 31, 2323-2341.

    547)

    G. Bringmann, T.A.M. Gulder, K. Maksimenka, D. Kuckling, W. Tochtermann; A borderline case between meso and stable C1: an axially chiral, yet configurationally semi-stable biphenyl with two oppositely configured [10]paracyclophane portions; Tetrahedron 2005, 61, 7241-7246.

    546)

    G. Bringmann, G. Lang, K. Maksimenka, A. Hamm, T.A.M. Gulder, A. Dieter, A.T. Bull, J.E.M. Stach, N. Kocher, W.E.G. Müller, H.-P. Fiedler; Gephyromycin, the First Bridged Angucyclinone, from Streptomyces griseus Strain NTK 14; Phytochemistry 2005, 66, 1366-1373.

    545)

    E. Straube, W. Völkel, G. Bringmann, W. Dekant; Reaction of nitroso derivatives of dinitropyrenes with sulfhydryl groups of peptides and hemoglobin in vitro and in rats; Xenobiotica 2005, 35, 1147-1164.

    544)

    G. Bringmann, G. Lang, T.A.M. Gulder, H. Tsuruta, J. Mühlbacher, K. Maksimenka, S. Steffens, K. Schaumann, R. Stöhr, J. Wiese, J.F. Imhoff, S. Perovic-Ottstadt, O. Boreiko, W.E.G. Müller; The first sorbicillinoid alkaloids, the antileukemic sorbicillactones A and B, from a sponge-derived Penicillium chrysogenum strain; Tetrahedron 2005, 61, 7252-7265.

    543)

    A. Aiello, M. D’Esposito, E. Fattorusso, M. Menna, W.E.G. Müller, S. Perovic-Ottstadt, H. Tsuruta, T.A.M. Gulder, G. Bringmann; Daminin, a Bioactive Pyrrole Alkaloid from the Mediterranean Sponge Axinella damicornis; Tetrahedron 2005, 61, 7266-7270.

    542)

    F. Tribl, M. Gerlach, K. Marcus, E. Asan, T. Tatschner, T. Arzberger, H.E. Meyer, G. Bringmann, P. Riederer; “Subcellular Proteomics” of Neuromelanin Granules Isolated from the Human Brain; Mol. Cell. Proteomics 2005, 4, 945-957.

    541)

    G. Bringmann, M. Dreyer, H. Kopff, H. Rischer, M. Wohlfarth, H.A. Hadi, R. Brun, H. Meimberg, G. Heubl; ent-Dioncophylleine A and Related Dehydrogenated Naphthylisoquinoline Alkaloids, the First Asian Dioncophyllaceae-Type Alkaloids, from the “New” Plant Species Ancistrocladus benomensis; J. Nat. Prod. 2005, 68, 686-690.

    540)

    G. Bringmann, A.J. Price Mortimer, P.A. Keller, M.J. Gresser, J. Garner, M. Breuning; The Atroposelective Synthesis of Axially Chiral Biaryl Compounds; Angew. Chem. 2005, 117, 5518-5563; Angew. Chem. Int. Ed. 2005, 44, 5384-5427.

    539)

    J.M. Wanjohi, A. Yenesew, J.O. Midiwo, M. Heydenreich, M.G. Peter, M. Dreyer, M. Reichert, G. Bringmann; Three dimeric anthracene derivatives from the fruits of Bulbine abyssinica; Tetrahedron 2005, 61, 2667-2674.

    538)

    G. Bringmann, I. Kajahn, C. Neusüß, M. Pelzing, S. Laug, M. Unger, U. Holzgrabe; Analysis of the glucosinolate pattern of Arabidopsis thaliana seeds by capillary zone electrophoresis coupled to electrospray ionization-mass spectrometry; Electrophoresis 2005, 26, 1513-1522.

    537)

    M. Benitez, G. Bringmann, M. Dreyer, H. Garcia, H. Ihmels, M. Waidelich, K. Wissel; Design of a Chiral Mesoporous Silica and its Application as a Host for Stereoselective Di-п-methane Rearrangements; J. Org. Chem. 2005, 70, 2315-2321.

    536)

    H. Rischer, G. Heubl, H. Meimberg, M. Dreyer, H.A. Hadi, G. Bringmann; Ancistrocladus benomensis (Ancistrocladaceae): a new species from Peninsular Malaysia; Blumea 2005, 50, 357-365.

    535)

    T. Mülhaupt, H. Kaspar, S. Otto, M. Reichert, G. Bringmann, T. Lindel; Isolation, Structural Elucidation, and Synthesis of Curcutetraol; Eur. J. Org. Chem. 2005, 334-341.

    534)

    C. Loeffler, S. Berger, A. Guy, T. Durand, G. Bringmann, M. Dreyer, U. van Rad, J. Durner, M.J. Mueller; B1-Phytoprostanes trigger plant defense and detoxification responses; Plant Physiol. 2005, 137, 328-340.

    2004

    533)

    F. Bracher, W.J. Eisenreich, J. Mühlbacher, M. Dreyer, G. Bringmann; Saludimerines A and B, Novel-Type Dimeric Alkaloids with Stereogenic Centers and Configurationally Semistable Biaryl Axes; J. Org. Chem. 2004, 69, 8602-8608.

    532)

    J.M. Scher, J. Zapp, H. Becker, N. Kather; J. Kolz, A. Speicher, M. Dreyer, K. Maksimenka, G. Bringmann; Optically active bisbibenzyls from Bazzania trilobata: isolation and stereochemical analysis by chromatographic, chiroptical, and computational methods; Tetrahedron 2004, 60, 9877-9881.

    531)

    M. Müller, K. Lamottke, W. Steglich, S. Busemann, M. Reichert, G. Bringmann, P. Spiteller; Biosynthesis and Stereochemistry of Phlegmacin-Type Fungal Pigments; Eur. J. Org. Chem. 2004, 4850-4855.

    530)

    A. Pérez, R. Ramírez-Durón, A. Piñeyro-López, N. Waksman, M. Reichert, G. Bringmann; The Absolute Configuration of Peroxisomicines A1 and A2; Tetrahedron 2004, 60, 8547-8552.

    529)

    E. Sauer, M. Merdanovic, A. Price Mortimer, G. Bringmann, J. Reidl; PnuC and the Utilization of the Nicotinamide Riboside Analog 3-Aminopyridine in Haemophilus influenzae; Antimicrob. Agents Chemother. 2004, 48, 4532-4541.

    528)

    G. Bringmann, D. Feineis, R. God, K. Maksimenka, J. Mühlbacher, K. Messer, M. Münchbach, K.-P. Gulden, E.-M. Peters, K. Peters; Resolution and chiroptical properties of the neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo) and related compounds: quantum chemical CD calculations and X-ray diffraction analysis; Tetrahedron 2004, 60, 8143-8151.

    527)

    J. Hartung, R. Kneuer, C. Rummey, G. Bringmann; On the 6-endo Selectivity in 4-Penten-1-oxyl Radical Cyclizations; J. Am. Chem. Soc. 2004, 126, 12121-12129.

    526)

    G. Bringmann, M. Dreyer, H. Rischer, K. Wolf, H.A. Hadi, R. Brun, H. Meimberg, G. Heubl; Ancistrobenomine A, the First Naphthylisoquinoline Oxygenated at Me-3, and Related 5,1’-Coupled Alkaloids, from the ‘New’ Plant Species Ancistrocladus benomensis; J. Nat. Prod. 2004, 67, 2058-2062.

    525)*

    G. Bringmann, G. Lang, T. Gulder, K. Schaumann, S. Steffens, W.E.G. Müller, S. Perović, J.F. Imhoff; Sorbifuranone, Sorbivineton, Sorbivinetol und Derivate dieser Verbindungen; Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 10 2004 005 106.2), filed 02.02.04.

    524)*

    G. Bringmann, G. Lang, K. Maksimenka, U. Hentschel, D. Stalke, N. Kocher, H.-P. Fiedler, A.T. Bull, S. Perović, W.E.G. Müller; O-Verbrückte Angucyclinone: Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 10 2004 004 906.8), filed 30.01.04.

    523)*

    G. Bringmann, G. Lang, T. Gulder, K. Schaumann, W.E.G. Müller, S. Perović, R. Stöhr, J. Wiese, R. Schmaljohann, J.F. Imhoff; Verfahren zur Herstellung von Sorbicillacton A; German Patent Application (DE 102 004 004 901.7), filed 30.01.04.

    522)

    R.S. Akundi, A. Macho, E. Munoz, K. Lieb, G. Bringmann, H.-W. Clement, M. Hüll, B.L. Fiebich; 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline-induced apoptosis in the human neuroblastoma cell line SK-N-SH; J. Neurochem. 2004, 91, 263-273.

    521)*

    G. Bringmann, K. Maksimenka, T. Gulder, K. Schaumann, S. Perović, W.E.G. Müller, J. Hiort, R. Ebel, P. Proksch; Aspernigrin B und Aspernigrin-B-Derivate, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 102 004 002 884.2), filed 20.01.04.

    520)

    G. Bringmann, J. Mühlbacher, M. Reichert, M. Dreyer, J. Kolz, A. Speicher; Stereochemistry of Isoplagiochin C, a Macrocyclic Bisbibenzyl from Liverworts; J. Am. Chem. Soc. 2004, 126, 9283-9290.

    519)*

    G. Bringmann, G. Lang, H. Tsuruta, E. Fattorusso, A. Aiello, M. D’esposito, M. Menna, W.E.G. Müller, H.C. Schröder; S. Perović; Neue medizinisch einsetzbare Pyrrolalkaloide: Verfahren zu ihrer Isolierung, Synthese, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 102 004 002 885.0), filed 20.01.2004.

    518)

    G. Bringmann, M. Dreyer, M. Michel, F. Tayman, R. Brun; Ancistroheynine B and two further 7,3’-coupled naphthylisoquinoline alkaloids from Ancistrocladus heyneanus; Phytochemistry 2004, 65, 2903-2907.

    517)

    J. Hiort, K. Maksimenka, M. Reichert, S. Perović-Ottstadt, W.H. Lin, V. Wray, K. Steube, K. Schaumann, H. Weber, P. Proksch, R. Ebel, W.E.G. Müller, H. Weber; G. Bringmann; New Natural Products from the Sponge-Derived Fungus Aspergillus niger; J. Nat. Prod. 2004, 67, 1532-1543.

    516)

    G. Bringmann, R.-M. Pfeifer, P. Schreiber, K. Hartner, N. Kocher, R. Brun, K. Peters, E.-M. Peters, M. Breuning; Synthesis and antitrypanosomal activity of 2-aminomethyl-1-(2-oxyphenyl)naphthalenes; Tetrahedron 2004, 60, 6335-6344.

    515)

    G. Bringmann, M. Dreyer, J.H. Faber, P.W. Dalsgaard, D. Stærk, J.W. Jaroszewski, H. Ndangalasi, F. Mbago, R. Brun, S. Brøgger Christensen; Ancistrotanzanine C and Related 5,1’- and 7,3’-Coupled Naphthylisoquinoline Alkaloids from Ancistrocladus tanzaniensis; J. Nat. Prod. 2004, 67, 743-748.

    514)

    G. Bringmann, Y. Reichert, V.V. Kane; The total synthesis of streptonigrin and related antitumor antibiotic natural products; Tetrahedron 2004, 60, 3539-3574.

    513)

    G. Bringmann, G. Lang, M. Michel, M. Heubes; Stereochemical assignment of the fungal metabolite xestodecalactone A by total synthesis; Tetrahedron Lett. 2004, 45, 2829-2831.

    512)

    W.E.G. Müller, N.J. Thakur, A.N. Thakur, H. Ushijima, A. Krasko, G. Le Pennec, M.M. Indap, , S. Perović-Ottstadt, H.C. Schröder, G. Lang, G. Bringmann; Matrix-mediated canal formation in primmorphs from the sponge Suberites domuncula involves the expression of a CD36 receptor-ligand system; J. Cell Science 2004, 117, 2579-2590.

    511)

    G. Bringmann, G. Lang, S. Steffens, K. Schaumann; Petrosifungins A and B, Novel Cyclodepsipeptides from a Sponge-Derived Strain of Penicillium brevicompactum; J. Nat. Prod. 2004, 67, 311-315.

    510)

    M. Unger, M. Dreyer, S. Specker, S. Laug, M. Pelzing, C. Neusüß, U. Holzgrabe, G. Bringmann; Analytical Characterisation of Crude Extracts from an African Ancistrocladus Species Using High-Performance Liquid Chromatography and Capillary Electrophoresis Coupled to Ion Trap Mass Spectrometry; Phytochem. Anal. 2004, 15, 21-26.

    509)

    G. Bringmann, R.-M. Pfeifer, P. Schreiber, K. Hartner, M. Schraut, M. Breuning; The ‘lactone method’: enantioselective preparation of novel P,N-biaryl ligands and their use in the synthesis of the biarylic alkaloids, ancistrotanzanine B and ancistroealaine A; Tetrahedron 2004, 60, 4349-4360.

    508)

    G. Bringmann, R.-M. Pfeifer, M. Breuning, M. Reichert, K. Messer, M. Schraut, G. Tóth; Structure of trans-Isoshinanolone in the Crystal and in Solution; Z. Naturforsch. 2004, 59b, 100-105.

    2003

    507)

    G. Bringmann, R.-M. Pfeifer, C. Rummey, K. Hartner, M. Breuning; Synthesis of Enantiopure Axially Chiral C3-Symmetric Tripodal Ligands and Their Application as Catalysts in the Asymmetric Addition of Dialkylzinc to Aldehydes; J. Org. Chem. 2003, 68, 6859-6863.

    506)

    G. Bringmann, A. Hamm, M. Schraut; Atroposelective Biaryl Coupling with Chiral Catalysts: Total Synthesis of the Antileishmanial Naphthylisoquinoline Alkaloids Ancistrotanzanine B and Ancistroealaine A; Org. Lett. 2003, 5, 2805-2808.

    505)*

    W.E.G. Müller, N.J. Thakur, A.N. Thakur, H.C. Schröder, G. Lang, H. Tsuruta, G. Bringmann; 2-Methylthio-1,4-naphthochinon und 2-Methylthio-1,4-naphthochinon-Derivate, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 103 437 98.3), filed 22.09.2003.

    504)

    W. Tochtermann, D. Kuckling, C. Meints, J. Kraus, G. Bringmann; Bridged bioxepines and bi[10]paracyclophanes - synthesis and absolute configuration of a bi[10]paracyclophane with two chiral planes and one chiral axis; Tetrahedron 2003, 59, 7791-7801.

    503)

    A. Dieter, A. Hamm, H.-P. Fiedler, M. Goodfellow, W.E.G. Müller, R. Brun, W. Beil, G. Bringmann; Pyrocoll, an antibiotic, antiparasitic, and antitumor compound produced by a novel alkalophilic Streptomyces strain; J. Antibiot. 2003, 56, 639-646.

    502)

    G. Bringmann, M. Breuning, R.-M. Pfeifer, C. P. Schreiber; Atropo-Enantioselective Synthesis of a C3-Symmetric Tripodal Ligand with Three Axially Chiral Biaryl Subunits; Tetrahedron: Asymmetry 2003, 14, 2225-2228.

    501)*

    G. Bringmann, U. Hentschel, W. Ziebuhr, S. Kozitskaya, G. Lang, K. Schaumann, S. Steffens, W.E.G. Müller; Tajixanthonhydrat und Tajixanthonhydrat-Derivate, deren biologische Aktivitaeten und deren Verwendung; German Patent Application (DE 103 29 874.6), filed 02.07.2003.

    500)

    G. Bringmann, M. Dreyer, J.H. Faber, P.W. Dalsgaard, D. Stærk, J. Jaroszewski, H. Ndangalasi, F. Mbago, R. Brun, M. Reichert, K. Maksimenka, S. Brøgger Christensen; Ancistrotanzanine A, the First 5,3’-Coupled Naphthylisoquinoline Alkaloid, and Two Further, 5,8’-Linked Related Compounds from the Newly Described Plant Species Ancistrocladus tanzaniensis; J. Nat. Prod. 2003, 66, 1159-1165.

    499)

    N. Stiefl, G. Bringmann, C. Rummey, K. Baumann; Evaluation of extended parameter sets for the 3D-QSAR technique MaP: Implications for interpretability and model quality exemplified by antimalarially active naphthylisoquinoline alkaloids; J. Comput.-Aided Mol. Des. 2003, 17, 347-365.

    498)

    G. Bringmann, C. Schneider, U. Möhler, R.-M. Pfeifer, R. Götz, L. Aké Assi, E.-M. Peters, K. Peters; Two Atropisomeric N-Methyldioncophyllines A and N-Methylphylline, their Naphthalene-Free Heterocyclic Moiety, from Ancistrocladus barteri; Z. Naturforsch. 2003, 58b, 577-584.

    497)

    K. Peters, E.-M. Peters, A. Wuzik, R.-M. Pfeifer, G. Bringmann; Crystal structure of 3’-benzyloxy-2’-naphthyl-1-bromo-2-naphthoate, C28H19BrO3; Z. Kristallogr. NCS. 2003, 218, 209-210.

    496)

    K. Kamikawa, K. Norimura, M. Furusyo, T. Uno, Y. Sato, A. Konoo, G. Bringmann, M. Uemura; Planar Chiral (h-6-Arene) Ruthenium Cp Complexes in Organic Synthesis: Diastereoselective Complexation of Arene Compounds with Benzylic Alcohol and Its Synthetic Application to Chiral Biaryls; Organometallics 2003, 22, 1038-1046.

    495)*

    G. Bringmann, C. Rummey, S. Neumann, R. Brun, A. Stich, V. Hörr, W.E.G. Müller; Medizinisch nützliche 3,3-Dimethyl-8-oxoisochinoline und deren Derivate; Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 103 03 254.1-44); filed 28.01.2003; PCT/EP03/14849.

    494)

    G. Bringmann, G. Lang, S. Steffens, E. Günther, K. Schaumann; Evariquinone, isoemericellin, and stromemycin from a sponge derived strain of the fungus Emericella variecolor; Phytochemistry 2003, 63, 437-443.

    493)

    G. Bringmann, R.-M. Pfeifer, C. Rummey, T. Pabst, D. Leusser, D. Stalke; Structural Investigation of a Configurationally Stable Seven-Membered Bridged Biaryl of Relevance for Atroposelective Biaryl Synthesis; Z. Naturforsch. 2003, 58b, 231-236.

    492)

    G. Bringmann, C. Rummey; 3D-QSAR Investigations on Antimalarial Naphthylisoquinoline Alkaloids, by Comparative Molecular Similarity Indices Analysis (CoMSIA), Based on Different Alignment Approaches; J. Chem. Inf. Comput. Sci. 2003, 43, 304-316.

    491)

    G. Bringmann, U. Holzgrabe, V. Hoerr, A. Stich; Antitrypanosomal naphthylisoquinoline alkaloids and related compounds; Pharmazie 2003, 58, 343-346.

    490)

    G. Bringmann; From tropical lianas to novel antiplasmodial agents: The naphthylisoquinoline alkaloids; in Drugs against parasitic diseases: R&D methodologies and issues (Eds. A.H. Fairlamb, R.G. Ridley, H.J. Vial), World Health Organisation, Geneva, 2003, 145-152.

    489)

    G. Bringmann, W. Saeb, M. Rückert, J. Mies, M. Michel, V. Mudogo, R. Brun; Ancistrolikokine D, a 5,8’-coupled naphthylisoquinoline alkaloid, and related natural products from Ancistrocladus likoko; Phytochemistry 2003, 62, 631-636.

    488)*

    G. Bringmann, R.-M. Pfeifer, R. Brun, W.E.G. Müller; Medizinisch nützliche 1-Phenyl-2-aminomethylnaphthaline, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 103 01 650.3); filed 17.01.2003; issued 05.08 2004; PCT/EP03/14848.

    487)

    G. Bringmann, K.-P. Gulden, S. Busemann; Calculation of circular dichroism spectra of michellamines A and C, based on a complete conformational analysis; Tetrahedron 2003, 59, 1245-1253.

    486)

    G. Bringmann, G. Lang, J. Mühlbacher, K. Schaumann, S. Steffens, P.G. Rytik, U. Hentschel, J. Morschhäuser, W.E.G. Müller; Sorbicillactone A, a Strucurally Unprecedented Bioactive Novel-Type Alkaloid from a Sponge-Derived Fungus; in Marine Mol. Biol. (Ed. W.E.G. Müller), Springer Verlag, Berlin, 2003, pp. 231-253.

    485)

    G. Bringmann, G. Lang; Full Absolute Stereostructures of Natural Products Directly From Crude Extracts: the HPLC-MS/MS-NMR-CD ‘Triad’; in Marine Mol. Biol. (Ed. W.E.G. Müller), Springer Verlag, Berlin, 2003, pp. 89-116.

    484)*

    G. Bringmann, G. Lang, J. Mühlbacher, K. Schaumann, S. Steffens, W.E.G. Müller; Sorbicillacton A und Sorbicillacton-A-Derivate; Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 102 38 257.3), filed 21.08.02; PCT/EP03/07805. Issued 11.03.2004.

    483)

    G. Bringmann, K. Messer, B. Schwöbel, R. Brun, L. Aké Assi; Habropetaline A, an Antimalarial Naphthylisoquinoline Alkaloid from Triphyophyllum peltatum; Phytochemistry 2003, 62, 345-349.

    482)

    G. Bringmann, J. Mühlbacher, K. Messer, M. Dreyer, R. Ebel, B.W. Nugroho, V. Wray, P. Proksch; Cyclorocaglamide, the First Bridged Cyclopentatetrahydrobenzofuran, and a Related “Open Chain” Rocaglamide Derivative from Aglaia oligophylla; J. Nat. Prod. 2003, 66, 80-85.

    481)

    C.T. Pabel, J. Vater, C. Wilde, P. Franke, J. Hofmeister, B. Adler, G. Bringmann, J. Hacker, U. Hentschel; Antimicrobial activities and matrix-assisted laser desorption/ionization mass spectrometry of Bacillus isolates from the marine sponge Aplysina aerophoba; Mar. Biotechnol. 2003, 5, 424-434.

    2002

    480)

    G. Bringmann, S. Tasler, R.-M. Pfeifer, M. Breuning; The directed synthesis of axially chiral ligands, reagents, catalysts, and natural products: through the lactone methodology; J. Organomet. Chem. 2002, 661, 49-65.

    479)

    G. Bringmann, M. Breuning, R.-M. Pfeifer, W.A. Schenk, K. Kamikawa, M. Uemura; The lactone concept: - a novel approach to the metal-assisted atroposelective construction of axially chiral biaryl systems; J. Organomet. Chem. 2002, 661, 31-47.

    478)

    G. Bringmann, D. Menche, J. Mühlbacher, M. Reichert, N. Saito, S. Pfeiffer, B.H. Lipshutz; On the Verge of Axial Chirality: Atroposelective Synthesis of the AB-Biaryl Fragment of Vancomycin; Org. Lett. 2002, 4, 2833-2836.

    477)

    R.A. Edrada, M. Heubes, G. Brauers, V. Wray, A. Berg, U. Gräfe, M. Wohlfarth, J. Mühlbacher, K. Schaumann, Sudarsono, G. Bringmann, P. Proksch; Online Analysis of Xestodecalactones A-C, Novel Bioactive Metabolites from the Fungus Penicillium cf. montanense and Their Subsequent Isolation from the Sponge Xestospongia exigua; J. Nat. Prod. 2002, 65, 1598-1604.

    476)

    G. Bringmann, T. Noll, H. Rischer; In vitro germination and establishment of tissue cultures of Bulbine caulescens and of two Kniphofia species (Asphodelaceae); Plant Cell Rep. 2002, 21, 125-129.

    475)

    B.M. Abegaz, M. Bezabih, T. Msuta, R. Brun, D. Menche, J. Mühlbacher, G. Bringmann; Gaboroquinones A and B, and 4’-O-Demethylknipholone-4’-O-ß- d-glucopyranoside, Phenylanthraquinones from the Roots of Bulbine frutescens; J. Nat. Prod. 2002, 65, 1117-1121.

    474)

    G. Bringmann, M. Wohlfarth, H. Rischer, J. Schlauer, R. Brun; Extract Screening by HPLC Coupled to MS-MS, NMR, and CD: A dimeric and three monomeric naphthylisoquinoline alkaloids from Ancistrocladus griffithii; Phytochemistry 2002, 61, 195-204.

    473)

    G. Bringmann, K. Messer, R. Brun, V. Mudogo; Ancistrocongolines A-D, New Naphthylisoquinoline Alkaloids from Ancistrocladus congolensis; J. Nat. Prod. 2002, 65, 1096-1101.

    472)

    G. Bringmann, D. Menche, J. Kraus, J. Mühlbacher, K. Peters, E.-M. Peters, R. Brun, M. Bezabih, B.M. Abegaz; Atropo-Enantioselective Total Synthesis of Knipholone and Related Antiplasmodial Phenylanthraquinones; J. Org. Chem. 2002, 67, 5595-5610.

    471)

    G. Bringmann, D. Feineis, R. God, K. Peters, E.-M. Peters, J. Scholz, F. Riederer, A. Moser; 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo) and Related Derivatives: Chemistry and Biochemical Effects on Catecholamine Biosynthesis; Bioorg. Med. Chem. 2002, 10, 2207-2214.

    470)

    S. Tasler, G. Bringmann; Biarylic Biscarbazole Alkaloids: Occurrence, Stereochemistry, Synthesis, and Bioactivity; Chem. Record 2002, 2, 114-127.

    469)

    M. Meyring, J. Mühlbacher, K. Messer, N. Kastner-Pustet, G. Bringmann, A. Mannschreck, G. Blaschke; In vitro biotransformation of (R) and (S)-thalidomide: Application of circular dichroism spectroscopy to the stereochemical characterization of the hydroxylated metabolites; Anal. Chem. 2002, 74, 3726-3735.

    468)

    P. Riederer, P. Foley, G. Bringmann, D. Feineis, R. Brückner, M. Gerlach; Biochemical and pharmacological characterization of TaClo: a biologically relevant neurotoxin?; Eur. J. Pharmacol. 2002, 442, 1-16.

    467)

    F. Riederer, A. Luborzewski, R. God, G. Bringmann, J. Scholz, D. Feineis, A. Moser; Modification of tyrosine hydroxylase activity by chloral derived ß-carbolines in vitro; J. Neurochem. 2002, 81, 814-819.

    466)

    G. Bringmann, K. Messer, K. Wolf, J. Mühlbacher, M. Grüne, R. Brun, A.M. Louis; Dioncophylline E from Dioncophyllum tholonnii, the first 7,3’-coupled Dioncophyllaceous naphthylisoquinoline alkaloid; Phytochemistry 2002, 60, 389-397.

    465)

    G. Bringmann, M. Münchbach, D. Feineis, K. Messer, S. Diem, M. Herderich, H.-W. Clement, C. Stichel-Gunkel, W. Kuhn; “Chiral” and “achiral” determination of the neurotoxin TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline) from blood and urine samples by high-performance liquid chromatography - electrospray ionization tandem mass spectrometry; J. Chromatogr. B 2002, 767, 321-332.

    464)

    H. Rischer, A. Hamm, G. Bringmann; Nepenthes insignis uses a C2-portion of the carbon skeleton of L-alanine acquired via its carnivorous organs, to build up the allelochemical plumbagin; Phytochemistry  2002, 59, 603-609.

    463)

    G. Bringmann, D. Menche, R. Brun, T. Msuta, B.M. Abegaz; Bulbine-Knipholone, a New Axially Chiral Phenylanthraquinone from Bulbine abyssinica (Asphodelaceae): Isolation, Structural Elucidation, Synthesis, and Antiplasmodial Activity; Eur. J. Org. Chem. 2002, 1107-1111.

    462)

    G. Bringmann, J. Hinrichs, P. Henschel, J. Kraus, K. Peters, E.-M. Peters; Atropo-Enantioselective Synthesis of the Natural Bicoumarin (+)-Isokotanin A via a Configurationally Stable Biaryl Lactone; Eur. J. Org. Chem. 2002, 1096-1106.

    461)

    G. Bringmann, H. Rischer, J. Schlauer, K. Wolf, A. Kreiner, M. Duschek, L. Aké Assi; The Tropical Liana Triphyophyllum peltatum (Dioncophyllaceae): Formation of Carnivorous Organs is Only a Facultative Prerequisite for Shoot Elongation; Carniv. Pl. Newslett. 2002, 31, 44-52.

    460)

    G. Bringmann, M. Breuning, P. Henschel, J. Hinrichs; Asymmetric Synthesis of (M)-2-Hydroxymethyl-1(2-Hydroxy-4,6-dimethylphenyl)naphthalene via a Configurationally Unstable Biaryl Lactone; Org. Syntheses 2002, 79, 72-83.

    459)

    A. Schultz, S. Laschat, M. Morr, S. Diele, M. Dreyer, G. Bringmann; Highly Branched Alkanoic Acids from the Preen-Gland Wax of the Domestic Goose as Building Blocks for Chiral Triphenylens; Helv. Chim. Acta 2002, 85, 3909-3918.

    458)*

    G. Bringmann, P. Proksch, M. Heubes, R.A. Edrada, J.K. Sudarsono, E. Günther (Zentaris AG); Neue Decalactone aus assoziierten Pilzen mariner Schwämme und deren synthetische Derivate als Arzneimittel. - Novel Decalactones from Associated Fungi of Marine Sponges and their Synthetic Derivatives as Medicaments; International Patent Application (PCT/EP 02/04676); Filed: 09.05.2001. International Publication Number: WO 02/092589 A2. Issued 21.11.2002.

    2001

    457)

    K. Kamikawa, M. Furusyo, T. Uno, Y. Sato, A. Konoo, G. Bringmann, M. Uemura; Diastereoselective Ruthenium-Cp Complexation of Enantiopure Arene Compounds Possessing Stereogenic Benzylic Alcohol Functions; Org. Lett. 2001, 3, 3667-3670.

    456)

    G. Bringmann, D. Feineis; Stress-Related Polyketide Metabolism in Ancistrocladaceae and Dioncophyllaceae; J. Exp. Bot. 2001, 52, 2015-2022.

    455)

    G. Bringmann, D. Menche; Stereoselective Total Synthesis of Axially Chiral Natural Products via Biaryl Lactones; Acc. Chem. Res.2001, 34, 615-624.

    454)

    G. Bringmann, H. Rischer; In vitro propagation of the alkaloid-producing, rare African liana Triphyophyllum peltatum (Dioncophyllaceae); Plant Cell Rep. 2001, 20, 591-595.

    453)

    G. Bringmann, K. Wolf, M. Meininger, M. Rokitta, A. Haase; In vivo 19F NMR Chemical Shift Imaging of Ancistrocladaceae; Protoplasma 2001, 218, 134-143.

    452)

    H. Ihmels, K. Faulhaber, C. Sturm, G. Bringmann, K. Messer, N. Gabellini, D. Vedaldi, G. Viola; Acridizinium Salts as a Novel Class of DNA-Binding and Site-Selective DNA-Photodamaging Chromophores; Photochem. Photobiol. 2001, 74, 505-511.

    451)

    G. Bringmann, J. Schlauer, H. Rischer, M. Wohlfarth, R. Haller, S. Bär, R. Brun; Antidesmone, a novel antitrypanosomal alkaloid; Pharm. Pharmacol. Lett. 2001, 11, 47-48.

    450)

    G. Bringmann, M. Wohlfarth; H. Rischer, M. Heubes, W. Saeb, S. Diem, M. Herderich, J. Schlauer; A Photometric Screening Method for Dimeric Naphthylisoquinoline Alkaloids and Complete On-Line Structural Elucidation of a Dimer in Crude Plant Extracts, by the LC-MS/LC-NMR/LC-CD Triad; Anal. Chem. 2001, 73, 2571-2577.

    449)

    G. Bringmann, A. Wuzik, O. Schupp, J. Kümmel, W.A. Schenk; Atropo-enantioselective ring cleavage of Lewis acid modified biaryl thionolactones; Organometallics 2001, 20, 1692-1694.

    448)

    G. Bringmann, M. Münchbach, D. Feineis, K. Faulhaber, H. Ihmels; Studies on single-strand scissions to cell-free plasmid DNA by the dopaminergic neurotoxin ‘TaClo’ (1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline); Neurosci. Lett. 2001, 304, 41-44.

    447)

    G. Bringmann, S. Tasler; Synthesis of Methylene-Bridged Binary Carbazole Alkaloids and a Related Tricarbazole; Tetrahedron 2001, 57, 2337-2343.

    446)

    G. Bringmann, T. Pabst, P. Henschel, M. Michel; First total synthesis of the mastigophorenes C and D and of simplified unnatural analogs; Tetrahedron 2001, 57, 1269-1275.

    445)

    G. Bringmann, D. Menche; First, Atropo-enantioselective Total Synthesis of the Axially Chiral Phenylanthraquinone Natural Products Knipholone and 6’-O-Methylknipholone; Angew. Chem. 2001, 113, 1733-1736; Angew. Chem. Int. Ed. 2001, 40, 1687-1690.

    444)

    G. Bringmann, A. Hamm, J. Kraus, M. Ochse, A. Noureldeen, D. Jumbam; Gardenamide A from Rothmannia urcelliformis (Rubiaceae) - Isolation, Absolute Stereostructure, and Biomimetic Synthesis from Genipine; Eur. J. Org. Chem. 2001, 1983-1987.

    443)

    G. Bringmann, C. Günther, P. Henschel, K. Peters, E.-M. Peters; First Total Synthesis of the 7,6’-Coupled Antifungal Naphthylisoquinoline Alkaloid Dioncophylline B; Tetrahedron 2001, 57, 1253-1259.

    442)

    H. Ihmels, K. Faulhaber, K. Wissel, G. Bringmann, K. Messer, G. Viola, D. Vedaldi; Synthesis and Investigation of the DNA-Binding and DNA-Photodamaging Properties of Indolo[2,3-b]-Quinolizinium Bromide; Eur. J. Org. Chem. 2001, 1157-1161.

    441)

    G. Bringmann, S. Tasler, H. Endress, J. Mühlbacher; En route to the first stereoselective synthesis of axially chiral biscarbazole alkaloids; J. Chem. Soc., Chem. Commun. 2001, 761-762.

    440)

    G. Bringmann, S. Tasler, H. Endress, J. Kraus, K. Messer, M. Wohlfarth, W. Lobin; Murrastifoline-F: First Total Synthesis, Atropo-Enantiomer Resolution, and Stereoanalysis of an Axially Chiral N,C-Coupled Biaryl Alkaloid; J. Am. Chem. Soc. 2001, 123, 2703-2711.

    439)

    G. Bringmann, J. Hinrichs, K. Peters, E.-M. Peters; Synthesis of a Chiral Aryl-Ferrocenyl Ligand, by Intramolecular Coupling to a Biaryl-Related Lactone; J. Org. Chem.2001, 66, 629-632.

    438)

    G. Bringmann, J. Mühlbacher, C. Repges, J. Fleischhauer; MD-Based CD Calculations on the Absolute Axial Configuration of the Naphthylisoquinoline Alkaloid Dioncophylline A; J. Comp. Chem. 2001, 22, 1273-1278.

    437)

    E.-M. Peters, K. Peters, G. Bringmann; Crystal structure of (1R,3R)-8-benzyloxy-N-benzyl-6-hydroxy-1,3-dimethyltetrahydroisoquinoline hydrobromide, (C9H6N)(CH3)2(CH2C6H5)(OH)(OCH2C6H5).HBr; Z. Kristallogr. NCS 2001, 216, 223-224.

    436)

    G. Bringmann, S. Tasler; Oxidative Aryl Coupling Reactions: A Biomimetic Approach to Configurationally Unstable or Axially Chiral Biaryl Natural Products and Related Bioactive Compounds; Tetrahedron 2001, 57, 331-343.

    435)

    G. Bringmann, C. Günther, M. Ochse, O. Schupp, S. Tasler; Axially Chiral Biaryls, a Multi-Facetted Class of Stereochemically, Biosynthetically, and Pharmacologically Intriguing Secondary Metabolites; in Progr. Chem. Org. Nat. Prod., Vol. 82 (Eds.: W. Herz, H. Falk, G.W. Kirby, R.E. Moore, C. Tamm) Wien, 2001, pp. 1-249.

    434)

    B. Chimanuka, G. François, G. Timperman, Y. Vanden Heyden, J. Holenz, J. Plaizier-Vercammen, G. Bringmann; A comparison of the stage-specific efficacy of chloroquine, artemether, and dioncophylline B, against the rodent malaria parasite Plasmodium chabaudi chabaudi in vivo; Parasitol. Res. 2001, 87, 795-803.

    433)

    M. Dreyer, B.W. Nugroho, F.I. Bohnenstengel, R. Ebel, V. Wray, L. Witte, G. Bringmann, J. Mühlbacher, M. Herold, P.D. Hung, L.C. Kiet, P. Proksch; New Insecticidal Rocaglamide Derivatives and Related Compounds from Aglaia oligophylla; J. Nat. Prod. 2001, 64, 415-420.

    432)

    E.-M. Peters, K. Peters, J. Hinrichs, G. Bringmann; Crystal structure of N,N-Diisopropyl 2-iodoferrocenecarboxamide, (C5H5)Fe(C5H3I)(C7H14NO); Z. Kristallogr. NCS 2001, 216, 221-222.

    431)

    G. Bringmann, M. Wenzel, H.P. Bringmann, J. Schlauer, L. Aké Assi, F. Haas; Uptake of the amino acid alanine by digestive leaves: proof of carnivory of the tropical liana Triphyophyllum peltatum (Dioncophyllaceae); Carniv. Pl. Newslett. 2001, 30, 15-21.

    430)

    R. Feling, K. Polborn, W. Steglich, J. Mühlbacher, G. Bringmann; The absolute configuration of the mushroom metabolites involutin and chamonixin; Tetrahedron 2001, 57, 7857-7863.

    429)

    S. Tasler, H. Endress, G. Bringmann; Synthesis of 2,2’-Biscarbazoles by Reductive Biaryl Coupling; Synthesis 2001, 1993-2002.

    428)

    E.-M. Peters, K. Peters, S. Tasler, H. Endress, G. Bringmann; Crystal structure of Ethyl 1-Methoxy-9-methyl-9H-carbazol-3-carboxylate, C12H6(OCH3)(CH3)CO2(C2H5); Z. Kristallogr. NCS. 2001, 216, 119-120.

    427)

    G. Bringmann, K. Messer, W. Saeb, E.-M. Peters, K. Peters; The absolute configuration of (+)-isoshinanolone and in situ LC-CD analysis of its stereoisomers from crude extracts; Phytochemistry 2001, 56, 387-391.

    426)

    G. Bringmann, J. Hinrichs, T. Pabst, P. Henschel, K. Peters, E.-M. Peters; From Dynamic to Non-Dynamic Kinetic Resolution of Lactone-Bridged Biaryls: Synthesis of Mastigophorene B; Synthesis 2001, 155-167.

    2000

    425)

    G. Bringmann, M. Wohlfarth, M. Heubes; Observation of exchangeable protons by high-performance liquid chromatography-nuclear magnetic resonance spectroscopy and -electrospray ionization mass spectrometry: a useful tool for the hyphenated analysis of natural products; J. Chromatogr. A 2000, 904, 243-249.

    424)

    G. Bringmann, W. Saeb, J. Mies, K. Messer, M. Wohlfarth, R. Brun; One-Step Oxidative Dimerization of Genuine, Unprotected Naphthylisoquinoline Alkaloids to Give Michellamines and Other Bioactive Quateraryls; Synthesis 2000, 1843-1847.

    423)

    G. Bringmann, T. Pabst, P. Henschel, J. Kraus, K. Peters, E.-M. Peters, D.S. Rycroft, J. Connolly; Non-Dynamic and Dynamic Kinetic Resolution of Lactones with Stereogenic Centers and Axes: Stereoselective Total Synthesis of Herbertenediol and Mastigophorenes A and B; J. Am. Chem. Soc. 2000, 122, 9127-9133.

    422)

    K.L. Double, L. Zecca, P. Costi, M. Mauer, C. Griesinger, S. Ito, D. Ben-Shachar, G. Bringmann, R.G. Fariello, P. Riederer, M. Gerlach; Structural characteristics of human neuromelanin and synthetic dopamine melanins; J. Neurochem. 2000, 75, 2583-2589.

    421)

    G. Bringmann, A. Hamm, C. Günther, M. Michel, R. Brun, V. Mudogo; Ancistroealaines A and B, Two New Bioactive Naphthylisoquinolines, and Related Naphthoic Acids from Ancistrocladus ealaensis; J. Nat. Prod. 2000, 63, 1465-1470.

    420)

    G. Bringmann, H. Rischer, M. Wohlfarth, J. Schlauer; Biosynthesis of Antidesmone in Cell Cultures of Antidesma membranaceum (Euphorbiaceae): An Unprecedented Class of Glycine-Derived Alkaloids; J. Am. Chem. Soc. 2000, 122, 9905-9910.

    419)

    G. Bringmann, C. Günther, W. Saeb, J. Mies, A. Wickramasinghe, V. Mudogo, R. Brun; Ancistrolikokines A - C: New 5,8’-Coupled Naphthylisoquinoline Alkaloids from Ancistrocladus likoko; J. Nat. Prod. 2000, 63, 1333-1337.

    418)

    K. Wolf, A. van der Toorn, K. Hartmann, L. Schreiber, W. Schwab, A. Haase, G. Bringmann; Metabolite monitoring in plants with double-quantum filtered chemical shift imaging; J. Exp. Bot. 2000, 51, 2109-2117.

    417)

    G. Bringmann, W. Saeb, K. Messer, M. Wohlfarth, R. Brun; Jozipeltine A, a Novel, Unnatural Dimer of the Highly Hydroxylated Naphthylisoquinoline Alkaloid Dioncopeltine A; Tetrahedron 2000, 56, 5871-5875.

    416)

    G. Bringmann, J. Kraus, U. Schmitt, C. Puder, A. Zeeck; The Absolute Configuration of g-Rubromycin and Related Spiro Compounds, by Quantum Chemical CD Calculations; Eur. J. Org. Chem. 2000, 2729-2734.

    415)

    G. Bringmann, J. Schlauer, H. Rischer, M. Wohlfarth, J. Mühlbacher, A. Buske, A. Porzel, J. Schmidt, G. Adam; Revised Structure of Antidesmone, an Unusual Alkaloid from Tropical Antidesma Plants (Euphorbiaceae); Tetrahedron 2000, 56, 3691-3695.

    414)

    G. Bringmann, D. Feineis, R. God, R. Brückner, J.-A. Protzen, M. Blank, K. Peters, E.-M. Peters, B. Janetzky, H. Reichmann; Chemical Modification of the Mitochondrial Complex I Inhibitor 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline: Synthesis and Evaluation of N-Alkanoyl Derivatives; Z. Naturforsch. 2000, 55c, 620-630.

    413)

    G. Bringmann, J. Hinrichs, P. Henschel, K. Peters, E.-M. Peters; Synthesis of Constitutionally Unsymmetric 7-Membered Biaryl Lactones by Ni-Mediated Intramolecular Coupling; Synlett 2000, 1822-1824.

    412)

    P. Sand, D. Kavvadias, D. Feineis, P. Riederer, P. Schreier, M. Kleinschmitz, F.-C. Czygan, A. Abou-Mandour, G. Bringmann, H. Beckmann; Naturally occurring benzodiazepines: current status of research and clinical implications; Eur. Arch. Psychiatry Clin. Neurosci. 2000, 250, 194-202.

    411)

    K. Peters, E.-M. Peters, T. Pabst, G. Bringmann; Crystal structure of 3,8-Di-tert.-butyl-4-methoxy-1-methyl-9,10-(diphenylmethylidenedioxy)dibenzo[b,d]pyran-6-one, C6H[O2C(C6H5) 2](C4H9)COO(C6H)(CH3)(OCH3)(C4H9); Z. Kristallogr. NCS 2000, 215, 603-604.

    410)

    G. Bringmann, C. Günther, W. Saeb, J. Mies, R. Brun, L. Aké Assi; 8-O-Methyldionco-phyllinol B and revised structures of other 7,6’-coupled naphthylisoquinoline alkaloids from Triphyphyllum peltatum (Dioncophyllaceae); Phytochemistry 2000, 54, 337-346.

    409)

    G. Bringmann, W. Saeb, J. Kraus, R. Brun, G. François; Jozimine B, a Constitutionally Unsymmetric, Antiplasmodial ‘Dimer’ of the Naphthylisoquinoline Alkaloid Ancistrocladine; Tetrahedron 2000, 56, 3523-3531.

    408)

    G. Bringmann, R. Brückner, D. Feineis, E.-M. Peters, K. Peters; 2-Hexanoyl-1-tribromo-methyl-1,2,3,4-tetrahydro-ß-carboline: Crystal Structure Analysis of a Potent Inhibitor of Complex I of Mitochondrial Respiration; Z. Naturforsch. 2000, 55b, 94-99.

    407)

    H. Meimberg, P. Dittrich, G. Bringmann, J. Schlauer, G. Heubl; Molecular Phylogeny of Caryophyllidae s.l. based on matK sequences with special emphasis on carnivorous taxa; Plant Biol. 2000, 2, 218-228.

    406)

    G. Gille, T. Pabst, B. Janetzky, G. Bringmann, H. Reichmann, W.-D. Rausch; Neurotrophic effects of simplified mastigophorene analogs on mesencephalic dopaminergic cells in primary culture; Drug. Dev. Res. 2000, 50, 153-156.

    405)

    K. Peters, E.-M. Peters, M. Welter, G. Bringmann; Crystal structure of 1-(3’,5’-dimethoxy-phenyl)-2-methyloximinopropanol, C6H3(OCH3)2CH(OH)C(NOCH3)(CH3); Z. Kristallogr. NCS 2000, 215, 405-406.

    404)

    G. Bringmann, D. Feineis, R. Brückner, M. Blank, K. Peters, E.-M. Peters, H. Reichmann, B. Janetzky, C. Grote, H.-W. Clement, W. Wesemann; Bromal-Derived Tetrahydro-ß-carbolines as Neurotoxic Agents: Chemistry, Impairment of the Dopamine Metabolism, and Inhibitory Effects on Mitochondrial Respiration; Bioorg. Med. Chem. 2000, 8, 1467-1478.

    403)

    R. Cseh, M. Hetzer, K. Wolf, J. Kraus, G. Bringmann, R. Benz; Interaction of Phloretin with Membranes: On the Mode of Action of Phloretin at the Water-Lipid Interface; Eur. Biophys. J. 2000, 29, 172-183.

    402)

    G. Bringmann, J. Hinrichs, J. Kraus, A. Wuzik, T. Schulz; Non-Dynamic Kinetic Resolution of Configurationally Stable Biaryl Lactones by Reduction with Oxazaborolidine-Activated Borane: AM1 Studies and Experimental Verification; J. Org. Chem. 2000, 65, 2508-2516.

    401)

    G. Bringmann, M. Ochse, M. Michel; Gentrymine B, an N-Quaternary Ancistrocladus Alkaloid: Stereoanalysis, Synthesis, and Biomimetic Formation from Gentrymine A; Tetrahedron 2000, 56, 581-585.

    400)

    G. Bringmann, M. Wohlfarth, H. Rischer, M. Grüne, J. Schlauer; A new biosynthetic pathway to alkaloids in plants: acetogenic isoquinolines; Angew. Chem. 2000, 112, 1523-1525; Angew. Chem. Int. Ed. 2000, 39, 1464-1466.

    399)

    K. Peters, E.-M. Peters, T. Pabst, G. Bringmann; Crystal structure of (P,1’’S,2’’R,5’’S)-menthyl 4,4-di-tert.-butyl-2’-hydroxy-2,3,3’-trimethoxy-6’-methyl-1,1’-biphenyl-6-carboxylate, C6H(OCH3)2[C(CH3)3]CO2(C10H19)C6H(CH3)(OH)(OCH3)[C(CH3) 3]; Z. Kristallogr. NCS 2000, 215, 403-404.

    398)

    K. Peters, E.-M. Peters, T. Pabst, G. Bringmann; Crystal structure of (E)-1,2-dibromo-5-tert-butyl-3,4-dimethoxyphenyl)ethene, {C6H(OCH3) 2[C(CH3)3]Br}2C2H2; Z. Kristallogr. NCS 2000, 215, 401-402.

    397)

    K. Peters, E.-M. Peters, T. Pabst, G. Bringmann; Crystal structure of 3,8-di-tert-butyl-4,9,10-trimethoxy-1-methyl-dibenzo[b,d]pyran-6-thione, C6H(OCH3)2[C(CH3)3]CSO(C6H)(CH3)(OCH3)[(C(CH3) 3)]; Z. Kristallogr. NCS 2000, 215, 399-400.

    396)

    K. Peters, E.-M. Peters, T. Pabst, G. Bringmann; Crystal structure of (P)-4,4’-di-tert-butyl-2,2’,3,3’-tetramethoxy-6,6’-dimethylbiphenyl, {C6H(OCH3) 2(CH3)[C(CH3) 3]}2; Z. Kristallogr. NCS 2000, 215, 397-398.

    395)

    G. Bringmann, M. Ochse, R. Götz; First Atropo-Divergent Total Synthesis of Antimalarial Korupensamines A and B - by the ‘Lactone Method'; J. Org. Chem. 2000, 65, 2069-2077.

    394)

    G. Brauers, R.A. Edrada, R. Ebel, P. Proksch, V. Wray, A. Berg, U. Gräfe, C. Schächtele, F. Totzke, G. Finkenzeller, D. Marme, J. Kraus, M. Münchbach, M. Michel, G. Bringmann, K. Schaumann; Anthraquinones and Betaenone Derivatives from the Sponge-Associated Fungus Microsphaeropsis Species: Novel Inhibitors of Protein Kinases; J. Nat. Prod. 2000, 63, 739-745.

    393)

    G. Bringmann, R. Brückner, R. Mössner, D. Feineis, A. Heils, K.P. Lesch; Effect of trichlororomethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo) on human serotonergic cells; Neurochem. Res. 2000, 25, 837-843.

    392)

    G. Bringmann, M. Heubes, M. Breuning, L. Göbel, M. Ochse, B. Schöner, O. Schupp; Atropisomerization Barriers of Configurationally Unstable Biaryl Compounds, Useful Substrates for Atroposelective Conversions to Axially Chiral Biaryls; J. Org. Chem. 2000, 65, 722-728.

    391)

    K. Peters, E.-M. Peters, J. Hinrichs, G. Bringmann; Crystal structure of dinaphth[2,1-c:1’,2’-e]thiepin-3-(5H)-thione, (C10H6)CS2(CH2)(C10H6); Z. Kristallogr. NCS 2000, 215, 395-396.

    390)

    K. Peters, E.-M. Peters, A. Wuzik, G. Bringmann; Crystal structure of 1,4-dimethyl-6H-benzo[b]naphtho[1,2-d]pyran-6-one, C10H6(COO)C6H2(CH3) 2; Z. Kristallogr. NCS 2000, 215, 393-394.

    389)

    K. Peters, E.-M. Peters, A. Wuzik, G. Bringmann; Crystal structure of (2,5-dimethyl)phenyl 1-bromonaphthyl-2-carboxylate, C10H6Br(COO)C6H3(CH3) 2; Z. Kristallogr. NCS 2000, 215, 391-392.

    388)

    K. Peters, E.-M. Peters, W. Saeb, G. Bringmann; Crystal structure of 1-bromo-5-isopropoxy-4-methoxy-2-methylnaphthalene, C10H4(OC3H7)(OCH3)(CH3)Br; Z. Kristallogr. NCS 2000, 215, 389-390.

    387)

    G. Bringmann, R. Brückner, M Münchbach, D. Feineis, R. God, W. Wesemann, C. Grote, M. Herderich, S. Diem, K.-P. Lesch, R. Mössner, A. Storch; 'TaClo', a Chloral-Derived Mammalian Alkaloid with Neurotoxic Properties; in Neurotoxic Factors in Parkinson's Disease and Related Disorders. (Eds.: A. Storch, M.A. Collins) Kluwer Academics / Plenum Publishers, New York 2000, pp. 145-149.

    386)

    K. Peters, E.-M. Peters, R. Brückner, D. Feineis, G. Bringmann; Crystal structure of 2-acetyl-1-tribromomethyl-1,2,3,4-tetrahydro-ß-carboline, C11H10N2(CBr3)(COCH3); Z. Kristallogr. NCS 2000, 215, 221-222.

    385)

    G. Bringmann, M. Münchbach, M. Michel; Determination of chiral benzylic alcohols or their ethers, by ruthenium-mediated oxidative degradation; Tetrahedron: Asymmetry 2000, 11, 3167-3176.

    384)

    G. Bringmann, M. Ochse, G. Zotz, K. Peters, E.-M. Peters, R. Brun, J. Schlauer; 6-Hydroxyluteolin-7-O-(1’’a-rhamnoside) from Vriesea sanguinolenta Cogn. and Marchal (Bromeliaceae); Phytochemistry 2000, 53, 965-969.

    383)

    G. Bringmann; Sir Derek H.R. Barton - an exceptional scientist and extraordinary person - Grateful Memories by a previous postdoctoral Fellow of the gif era; in The Bartonian Legacy (Eds.: A. I. Scott, P. Potier), Imperial College Press, London 2000, pp 99-104.

    382)

    G. Bringmann, D. Feineis, W. Saeb, C. Hesselmann, E.-M. Peters, K. Peters; Dimethyl (2S,4S)- and (2R,4S)-5,5-Dimethyl-1,3-thiazolidine-2,4-dicarboxylates, Two Diastereomeric Glyoxylate-Derived Heterocycles; Z. Naturforsch. 2000, 55b, 208-212.

    381)

    G. Bringmann, C. Günther, J. Mühlbacher, M.D.L.P. Gunathilake, A. Wickramasinghe; New Tropane Alkaloids from Erythroxylum zeylanicum O.E. Schulz (Erythroxylaceae); Phytochemistry 2000, 53, 409-416.

    380)

    K. Peters, E.-M. peters, J. Hinrichs, G. Bringmann; Crystal structure of di(1,3,5-trimethyl-5,6-dihydrobenzo[k]phenanthridin-6-yl) peroxide, (C20H18NO)2; Z. Kristallogr. NCS 2000, 215, 57-58.

    379)

    K. Peters, E.-M. peters, R. Brückner, G. Bringmann; Crystal structure of 2-(2'-methyl-propanoyl)-1-tribromomethyl-1,2,3,4-tetrahydro-ß-carboline, C11H10N2[COCH(CH2)3]CBr3; Z. Kristallogr. NCS 2000, 215, 55-56.

    378)

    G. Bringmann, H. Rischer, M. Wohlfarth, J. Schlauer, L. Aké Assi; Droserone from cell cultures of Triphyophyllum peltatum (Dioncophyllaceae) and its biosynthetic origin; Phytochemistry 2000, 53, 339-343.

    377)

    G. Bringmann, T. Ortmann, D. Feineis, E.-M. Peters, K. Peters; A New Central Binaphthalene Building Block for Michellamine Syntheses; Synthesis, 2000, 383-388.

    376)

    G. Bringmann, D. Feineis; Novel Antiparasitic Biaryl Alkaloids from Westafrican Dioncophyllaceae Plants; Act. Chim. Thérapeut. 2000, 26, 151-171.

    1999

    375)

    G. Bringmann, C. Günther, D.N. Jumbam; Isolation of 4-O-ß-Glucopyranosylcaffeic Acid and Gallic Acid from Cyathea dregei Kunze (Cyatheaceae); Pharm. Pharmacol. Lett. 1999, 9, 41-43.

    374)

    G. Bringmann, K. Wolf, A. Haase, T. Lanz, J. Hiort, P. Proksch, W.E.G. Müller; Direct demonstration of spatial water distribution in the sponge Suberites domuncula by in vivo NMR imaging; Mar. Ecol. Progr. Ser. 1999, 189, 307-310.

    373)

    G. Bringmann, A. Wuzik, M. Breuning, P. Henschel, K. Peters, E.-M. Peters; Atropo-enantioselective synthesis of an axially chiral C1-symmetric phosphine ligand and its application in the asymmetric hydrosilylation of styrenes; Tetrahedron: Asymmetry 1999, 10, 3025-3031.

    372)

    G. Bringmann, H. Rischer, J. Schlauer, L. Aké Assi; In vitro propagation of Ancistrocladus abbreviatus Airy Shaw (Ancistrocladaceae); Plant Cell Tiss. Org. Cult. 1999, 57, 71-73.

    371)

    K. Peters, E.-M. Peters, T. Hartung, G. Bringmann; Crystal structure of (P)-1-(2-hydroxy-phenyl)-2-naphthoic acid (1S,2R,5S)-(+)-menthyl ester, C10H6[C6H4(OH)][COOC6H9(CH3)(C3H7)]; Z. Kristallogr. NCS 1999, 214, 553-554.

    370)

    K. Peters, E.-M. Peters, A. Wuzik, G. Bringmann; Crystal structure of 2-trifluormethyl-sulfonyloxy-dinaphtho[2,1-b:1',2'-d]pyran-4-one, C21H11O2(OSO2CF3); Z. Kristallogr. NCS 1999, 214, 551-552.

    369)

    K. Peters, E.-M. Peters, C. Vedder, G. Bringmann; Crystal structure of 1-(2'-benzoyl-4',6'-dimethylphenyl)-2-methylnaphthalene, [C10H6CH3][C6H2(OCH2C6H5)(OCH3)(CH3) 2]; Z. Kristallogr. NCS 1999, 214, 549-550.

    368)

    G. Bringmann, M. Breuning, R. Walter, A. Wuzik, K. Peters, E.-M. Peters; Synthesis of Axially Chiral Biaryls by Atropo-Diastereoselective Cleavage of Configurationally Unstable Biaryl Lactones with Menthol-Derived O-Nucleophiles; Eur. J. Org. Chem. 1999, 3047-3055.

    367)

    G. Bringmann, J. Kraus, D. Menche, K. Messer; Elucidation of the Absolute Configuration of Knipholone and Knipholone Anthrone by Quantum Chemical CD Calculations; Tetrahedron 1999, 55, 7563-7572.

    366)

    G. Bringmann, M. Breuning, S. Tasler, H. Endress, C.L.J. Ewers, L. Göbel, K. Peters, E.-M. Peters; Atropo-Diastereoselective Cleavage of Configurationally Unstable Biaryl Lactones with Alkali Metal Activated Primary 1-Arylethylamines; Chem. Eur. J. 1999, 5, 3029-3038.

    365)

    W.A. Schenk, J. Kümmel, I. Reuther, N. Burzlaff, A. Wuzik, O. Schupp, G. Bringmann; Atropo-Diastereoselective Ring Opening of Biaryl Thionolactones Using [CpRu{(S,S)-CHIRAPHOS}]+ as a Chiral Auxiliary; Eur. J. Inorg. Chem. 1999, 1745-1756.

    364)

    K. Peters, E.-M. Peters, C. Vedder, G. Bringmann; Crystal structure of 1-(2'-hydroxy-4',6'-dimethylphenyl)-2-(diphenylphosphanoyloxymethyl)-naphthalene-dichloromethane (1/1), [C10H6(CH2OPO(C6H5)2][C6H(CH3)3(OH)]·CH2Cl2; Z. Kristallogr. NCS 1999, 214, 547-548.

    363)

    G. Bringmann, J. Holenz, W. Saeb, L. Aké Assi, K. Hostettmann; Dioncophylline A as a Larvicide Against Aedes aegypti; Pharm. Pharmacol. Lett. 1999, 9, 24-25.

    362)

    G. François, B. Chimanuka, G. Timperman, J. Holenz, J. Plaizier-Vercammen, L. Aké Assi, G. Bringmann; Differential sensitivity of erythrocytic stages of the rodent malaria parasite Plasmodium chabaudi chabaudi to dioncophylline B, a highly active naphthylisoquinoline alkaloid; Parasitol. Res. 1999, 85, 935-941.

    361)

    G. Bringmann, M. Breuning, S. Tasler; The Lactone Concept: An Efficient Pathway to Axially Chiral Natural Products and Useful Reagents; Synthesis 1999, 525-558.

    360)

    K. Peters, E.-M. Peters, C. Günther, G. Bringmann; Crystal structure of 1-hydroxy-8-methoxy-3-methyl naphthalene, C10H5(OCH3)(OH)(CH3); Z. Kristallogr. NCS 1999, 214, 545-546.

    359)

    K. Peters, E.-M. Peters, S. Schneider, G. Bringmann; Crystal structure of 1-bromo-2-methyl-dinaphtho[2,1-b:1',2'-d]pyran-4-one, C21H10O2Br(CH3); Z. Kristallogr. NCS 1999, 214, 543-544.

    358)

    K. Peters, E.-M. Peters, M. Ochse, G. Bringmann; Crystal structure of 1-bromo-6-hydroxy-4-isopropoxy-8-methylnaphthalene, C10H4(OC3H7)(OH)(CH3)Br; Z. Kristallogr. NCS 1999, 214, 541-542.

    357)

    G. Bringmann, M. Wenzel, T.R. Kelly, M.R. Boyd, R.J. Gulakowski, R. Kaminsky; Octadehydromichellamine, a Structural Analog of the Anti-HIV Michellamines without Centrochirality; Tetrahedron 1999, 55, 1731-1740.

    356)

    G. Bringmann, M. Münchbach, K. Messer, D. Koppler, M. Michel, O. Schupp, M. Wenzel, A.M. Louis; Cis- and trans-isoshinanolone from Dioncophyllum thollonii: absolute configuration of two 'known', wide-spread natural products; Phytochemistry 1999, 51, 693-699.

    355)

    B.W. Nugroho, R.A. Edrada, V. Wray, L. Witte, G. Bringmann, M. Gehling, P. proksch; new Insecticidal Rocaglamide Derivatives and Related Compounds from Aglaia odorata (Meliaceae); Phytochemistry 1999, 51, 367-376.

    354)

    K. Peters, E.-M. Peters, S. Schneider, G. Bringmann; Crystal structure of 3-methoxy-2-naphthoic acid phenyl ester, C10H6(OCH3)(COOC6H5); Z. Kristallogr. NCS 1999, 214, 245-246.

    353)

    K. Peters, E.-M. Peters, M. Breuning, G. Bringmann; Crystal structure of 1-(2-hydroxy-4,6-dimethoxyphenyl)-2-propyl naphthoate, C10H6(COOC3H7)[C6H2(OCH3)2OH]; Z. Kristallogr. NCS 1999, 214, 251-252.

    352)

    K. Peters, E.-M. Peters, C. Vedder, G. Bringmann; Crystal structure of dibenzyldiphenylphosphonium bromide, (C6H5)2(CH2C6H5)2PBr; Z. Kristallogr. NCS 1999, 214, 249-250.

    351)

    K. Peters, E.-M. Peters, S. Schneider, G. Bringmann; Crystal structure of 2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-3-yl)-1-methoxynaphthalene, C10H6(OCH3)[C3H2NO(CH3)2]; Z. Kristallogr. NCS 1999, 214, 247-248.

    350)

    G. Bringmann, R. God, S. Fähr, D. Feineis, K. Fornadi, F. Fornadi; Identification of the dopaminergic neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline in Human Blood after Intake of the Hypnotic Chloral Hydrate; Anal. Biochem. 1999, 270, 167-175.

    349)

    G. Bringmann, M. Rückert, K. Messer, O. Schupp, A.M. Louis; Use of on-line high-perfomance liquid chromatography - nuclear magnetic resonance spectrometry coupling in phytochemical screening studies: rapid identification of metabolites in Dioncophyllum thollonii; J. Chromatogr. A 1999, 837, 267-272.

    348)

    G. Bringmann, J. Schlauer, K. Wolf, H. Rischer, U. Buschbom, A. Kreiner, F. Thiele, M. Duschek, L. Aké Assi; Cultivation of Triphyophyllum peltatum (Dioncophyllaceae), the Part-Time Carnivorous Plant; Carniv. Pl. Newslett. 1999, 28, 7-13.

    347)

    G. Bringmann, D. Herzberg, G. Adam, F. Balkenhohl, J. Paust; A Short and Productive Synthesis of (R)-a-Lipoic Acid; Z. Naturforsch. 1999, 54b, 655-661.

    346)

    G. Bringmann; Naturstoffchemie - neue Wirkstoffe für Medizin und Landwirtschaft; würzburg heute 1999, 67, 17-18.

    345)

    G. Bringmann, F. Teltschik, M. Michel, S. Busemann, M. Rückert, R. Haller, S. Bär, A. Robertson, R. Kaminsky; Ancistrobertsonines B, C, and D as well as 1,2-Didehydro-ancistrobertsonine D from Ancistrocladus robertsoniorum; Phytochemistry 1999, 52, 321-332.

    344)

    G. Bringmann, M. Ochse, K. Wolf, J. Kraus, K. Peters, E.-M. Peters, M. Herderich, L. Aké Assi, F.K. Tayman; 4-Oxonicotinamide-1-(1'-ß-d-ribofuranoside) from Rothmannia longiflora Salisb. (Rubiaceae); Phytochemistry 1999, 51, 271-276.

    343)

    G. Bringmann, D. Menche, M. Bezabih, B.M. Abegaz, R. Kaminsky; Antiplasmodial Activity of Knipholone and Related Natural Phenylanthraquinones; Planta Med. 1999, 65, 757-758.

    342)

    G. Wahl, D. Kleinhenz, A. Schorm, J. Sundermeyer, R. Stowasser, C. Rummey, G. Bringmann, C. Fickert, W. Kiefer; Peroxomolybdenum Complexes as Epoxidation Catalysts in Biphasic Hydrogen Peroxide Activation: Raman Spectroscopic Studies and Density Functional Calculations; Chem. Eur. J. 1999, 5, 3237-3251.

    341)

    W. Tochtermann, D. Kuckling, C. Meints, J. Kraus, G. Bringmann; Synthesis and absolute configuration of a bi[10]paracyclophane with two chiral planes and one chiral axis; Tetrahedron: Asymmetry 1999, 10, 21-24.

    340)

    G. Bringmann, K. Messer, M. Wohlfarth, J. Kraus, K. Dumbuya, M. Rückert; HPLC-CD On-Line Coupling in Combination with HPLC-NMR and HPLC-MS/MS for the Determination of the Full Absolute Stereostructure of New Metabolites in Plant Extracts; Anal. Chem. 1999, 71, 2678-2686.

    339)

    G. Bringmann, M. Breuning; Atropo-enantioselective reduction of configurationally unstable biaryl lactones with BINAL-H; Tetrahedron: Asymmetry 1999, 10, 385-390.

    338)

    S.E. Drewes, M.M. Horn, O.Q. Munro, N. Ramesar, M. Ochse, G. Bringmann, K. Peters, E.-M. Peters; Stereostructure, conformation and reactivity of a- and b-gardiol from Burchellia bubalina; Phytochemistry 1999, 50, 387-394.

    337)

    G. Bringmann, C. Günther; First Total Synthesis of Dioncophylline B, a 7,6'-Coupled Naphthylisoquinoline Alkaloid; Synlett 1999, 216-218.

    336)

    G. Bringmann, T. Pabst, D.S. Rycroft, J.D. Connolly; First Synthesis of Mastigophorenes A and B, by Biomimetic Oxidative Coupling of Herbertenediol; Tetrahedron Lett. 1999, 40, 483-486.

    335)

    G. Bringmann, W. Saeb, M. Rübenacker; Directed Joint Total Synthesis of the three Naphthylisoquinoline Alkaloids Dioncolactone A, Dioncopeltine A, and 5'-O-Demethyl-dioncophylline A; Tetrahedron 1999, 55, 423-432.

    334)

    G. Bringmann, J. Schlauer, M. Rückert, B. Wiesen, K. Ehrenfeld, P. Proksch, F.C. Czygan; Host-Derived Acetogenins Involved in the Incompatible Parasitic Relationship between Cuscuta reflexa (Convolvulaceae) and Ancistrocladus heyneanus (Ancistrocladaceae); Plant Biol. 1999, 1, 581-584.

    333)

    G. Bringmann, A. Wuzik, R. Stowasser, C. Rummey, L. Göbel, D. Stalke, M. Pfeiffer, W.A. Schenk; Synthesis and Atropo-Diastereoselective Ring Cleavage of a [Cp*Ru]-Complexed Biaryl Lactone: Experimental and Computational Investigations; Organometallics 1999, 18, 5017-5021.

    332)

    B. Janetzky, G. Gille, M. Abdel-mohsen, R. God, W.-D. Rausch, G. Bringmann, H. Reichmann; Effect of highly-halogenated ß-carbolines on dopaminergic cells in culture and on mitochondrial respiration; Drug Dev. Res. 1999, 46, 51-56.

    331)

    C. Eder, P. Proksch, V. Wray, K. Steube, G. Bringmann, R.W.M. van Soest, Sudarsono, E. Ferdinandus, L. A. Pattisina, S. Wiryowidagdo, W. Moka; New Alkaloids from the Indopacific Sponge Stylissa Carteri; J. Nat. Prod. 1999, 62, 184-187.

    330)

    M. Rückert, M. Wohlfarth, G. Bringmann; Characterization of protein mixtures by ion-exchange chromatography coupled on-line to nuclear magnetic resonance spectroscopy; J. Chromatogr. A 1999, 840, 131-135.

    329)

    A. Maier, J. Müller, P. Schneider, H.-P. Fiedler, I. Groth, F.S.K. Tayman, F. Teltschik, C. Günther, G. Bringmann; (2E,4Z)-Decadienoic acid and (2E,4Z,7Z)-decatrienoic acid, two herbicidal metabolites from Streptomyces viridochromogenes Tü 6105; Pestic. Sci. 1999, 55, 733-739.

    328)

    G. François, T. Steenackers, L. Aké Assi, W. Steglich, K. Lamottke, J. Holenz, G. Bringmann; Vismione H and structurally related anthranoid compounds of natural and synthetic origin as promising drugs against the human malaria parasite Plasmodium falciparum: structure-activity relationships; Parasitol. Res. 1999, 85, 582-588.

    327)

    G. Tóth, A. Simon, T. Linker, F. Rebien, J. Kraus, G. Bringmann; Elucidation of the conformations and absolute configurations of enantiomerically pure tetralin derivatives; Magn. Reson. Chem. 1999, 37, 53-59.

    326)

    A. Buske, S. Busemann, J. Mühlbacher, J. Schmidt, A. Porzel, G. Bringmann, G. Adam; Antidesmone, a novel type isoquinoline alkaloid from Antidesma membranaceum (Euphorbiaceae); Tetrahedron 1999, 55, 1079-1086.

    325)

    G. Bringmann, M. Rückert, W. Saeb, V. Mudogo; Characterization of metabolites in plant extracts of Ancistrocladus likoko by high-performance liquid chromatography coupled on line with 1H NMR spectroscopy; Magn. Res. Chem. 1999, 37, 98-102.

    324)

    G. Bringmann, S. Tasler; The Atropisomer-Selective Synthesis of Biologically Active and Synthetically Useful Chiral Biaryls; in Current Trends in Organic Synthesis (Eds.: C. Scolastico, F. Nicotra) Plenum Publishing Corporation, New York, 1999, pp. 105-116.

    1998

    323)

    M. Gerlach, A.-Y. Xiao, C. Heim, J. Lan, R. God, D. Feineis, G. Bringmann, P. Riederer, K.-H. Sontag; 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline increases extracellular serotonin and stimulates hydroxyl radical production in rats; Neurosci. Lett. 1998, 257, 17-20.

    322)

    K. Peters, E.-M. Peters, M. Blank, J.-A. Protzen, D. Feineis, R. God, G. Bringmann; (1R,3S)-1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline-3-carboxamide Methanol Solvate, a Potential Synthetic Precursor to Enantiomerically Pure TaClo; Acta Cryst. 1998, C54, 1005-1007.

    321)

    C. Fickert, V. Nagel, W. Kiefer, S. Möller, H. Jehle, W. Malisch, R. Stowasser, G. Bringmann; Matrix isolation Raman spectroscopy and photochemistry of (h5-C5H5)(CO)2Fe-SiH2R (R = H, CH3) in comparison with density functional calculations; J. Organomet. Chem. 1998, 566, 225-235.

    320)

    T. Linker, F. Rebien, G. Tóth, A. Simon, J. Kraus, G. Bringmann; Convenient Catalytic Synthesis and Assignment of the Absolute Configuration of Enantiomerically Pure Dihydronaphthalenes and Their Corresponding Epoxides; Chem. Eur. J. 1998, 4, 1944-1951.

    319)

    G. Bringmann, M. Wohlfarth, H. Rischer, M. Rückert, J. Schlauer; The Polyketide Folding Mode in the Biogenesis of Isoshinanolone and Plumbagin in Ancistrocladus heyneanus (Ancistrocladaceae); Tetrahedron Lett. 1998, 39, 8445-8448.

    318)

    J. Fleischhauer, A. Koslowski, C. Repges, K.-P. Gulden, G. Bringmann; The Absolute Configuration of Isoancistrocladine and 'Isohamatine' by Quantumchemical CD-calculations; Z. Naturforsch. 1998, 53a, 993-996.

    317)

    K. Peters, E.-M. Peters, A. Wuzik, G. Bringmann; Crystal structure of 2-benzyloxy-3-hydroxynaphthalene, C10H6(OH)OCH2C6H5; Z. Kristallogr. NCS 1998, 213, 565-567.

    316)

    K. Peters, E.-M. Peters, T. Ortmann, G. Bringmann; Crystal structure of methyl 4-amino-3-methoxybenzoate, C6H3NH2(OCH3)COOCH3; Z. Kristallogr. NCS 1998, 213, 563-564.

    315)

    K. Peters, E.-M. Peters, M. Ochse, G. Bringmann; Crystal structure of ethyl 1-(2-hydroxy-4,6-dimethoxy)naphthyl-2-carboxylate, C10H6(COOC2H5)C6H2(OH)OCH3)2; Z. Kristallogr. NCS 1998, 213, 561-562.

    314)

    K. Peters, E.-M. Peters, M. Ochse, G. Bringmann; Crystal structure of 2-bromo-5-isopropoxybenzoic acid, C6H3Br(COOH)(OC3H7); Z. Kristallogr. NCS 1998, 213, 559-560.

    313)

    K. Peters, E.-M. Peters, R. God, S. Fähr, G. Bringmann; Crystal structure of 1-trichloromethyl-2-propanoyl-1,2,3,4-tetrahydro-ß-carboline, C11H10N2(COC2H5)CCl3; Z. Kristallogr. NCS 1998, 213, 557-558.

    312)

    K. Peters, E.-M. Peters, M. Breuning, A. Wuzik, G. Bringmann; Crystal structure of 2-bromomethyl-1-(2-benzyloxy-4,6-dimethylphenyl)naphthalene, C10H6(CH2Br)C6H2(CH3)2OCH2C6H5; Z. Kristallogr. NCS 1998, 213, 555-556.

    311)

    G. Bringmann, M. Ochse; The Atropo-Divergent Preparation of Axially Chiral Biaryls Through the 'Lactone Methodology': Total Synthesis of Korupensamine B; Synlett 1998, 1294-1296.

    310)

    G. Bringmann, U. Dauer, J. Kraus; Hartree Fock Calculations on the Effects of Lewis Acids on the Helimerization Barrier of a Lactone-Bridged Biaryl; Tetrahedron 1998, 54, 12265-12268.

    309)

    G. Bringmann, M. Breuning; The Atropo-Enantioselective Reduction of Configurationally Unstable Biaryl Hydroxy Aldehydes - A Novel Approach to Axially Chiral Biaryls; Synlett 1998, 634-636.

    308)

    Y.F. Hallock, J.H. Cardellina II, M. Schäffer, G. Bringmann, G. François, M.R. Boyd; Korundamine A, a Novel HIV-Inhibitory and Antimalarial "Hybrid" Naphthylisoquinoline Alkaloid Heterodimer from Ancistrocladus korupensis; Bioorg. Med. Chem. Lett. 1998, 8, 1729-1734.

    307)*

    Bringmann, M. Wenzel, M.R. Boyd (U.S. Dept. Of Health and Human Services); Monomeric and Dimeric Arylisoquinoline Alkaloids and Derivatives Thereof; U.S. Patent Application No. 09/001,801 (31.12.97).

    306)

    G. Bringmann, D. Vitt, J. Kraus, M. Breuning; The ortho-Hydroxy-ortho'-Formyl Biaryl / Lactol Equilibrium: Quantumchemical Studies on Structure and Dynamics; Tetrahedron 1998, 54, 10691-10698.

    305)

    G. Bringmann, M. Breuning, H. Endress, D. Vitt, K. Peters, E.-M. Peters; Biaryl Hydroxy Aldehydes as Intermediates in the Metal-Assisted Atropo-Enantioselective Reduction of Biaryl Lactones: Structures and Aldehyde-Lactol Equilibria; Tetrahedron 1998, 54, 10677-10690.

    304)

    G. Bringmann, A. Wuzik, C. Vedder, M. Pfeiffer, D. Stalke; Palladium-mediated intramolecular acylation reaction in the attempted phosphinylation of a sterically hindered trifluoromethylsulfonyloxybiaryl carboxylic ester; J. Chem. Soc., Chem. Commun. 1998, 1211-1212.

    303)

    K. Peters, E.-M. Peters, S. Harmsen, G. Bringmann; Crystal structure of 2,2-dimethyl-1,3-bis-[3-benzyloxy-4,5-(diphenyl-methylidenedioxy)benzoyloxy]propane, [(C6H5)3C9H4O5]2(CH3)2C3H4; Z. Kristallogr. NCS 1998, 213, 335-336.

    302)

    G. Bringmann, S. Güssregen, D. Vitt, R. Stowasser; The Atropisomer-Selective Ring Cleavage of Helically Distorted, Configuratively Unstable Biaryl Lactones with a Chiral Metallated N-Nucleophile - the Complete PM3 Mechanistic Course and its Video Presentation; J. Mol. Model. 1998, 4, 165-175.

    301)

    R. Roscher, G. Bringmann, P. Schreier, W. Schwab; Radiotracer Studies on the Formation of 2,5-Dimethyl-4-hydroxy-3(2H)-furanone in Detached Ripening Strawberry Fruits; J. Agric. Food Chem. 1998, 46, 1488-1493.

    300)

    G. Bringmann, M. Rückert, J. Schlauer, M. Herderich; Separation and identification of dimeric naphthylisoquinoline alkaloids by liquid chromatography coupled to electrospray ionization mass spectrometry; J. Chromatogr. A 1998, 810, 231-236.

    299)

    A. Schneider, L.H. Gade, M. Breuning, G. Bringmann, I.J. Scowen, M. McPartlin; Cooperative Reactivity of Unsupported Early-Late Heterobimetallics: Ring Opening and Subsequent Decarbonylation of Biaryllactones; Organometallics 1998, 17, 1643-1645.

    298)

    G. Bringmann, M. Breuning; Enantioselective addition of diethylzinc to aldehydes using novel axially chiral 2-aminomethyl-1-(2'-hydroxyphenyl)naphthalene catalysts; Tetrahedron: Asymmetry 1998, 9, 667-679.

    297)

    G. Bringmann, A. Wuzik, J. Kraus, K. Peters, E.-M. Peters; Synthesis and Structure of a Novel Twofold Lactone-Bridged Ternaphthyl; Tetrahedron Lett. 1998, 39, 1545-1548.

    296)

    G. Bringmann, W. Saeb, R. God, M. Schäffer, G. François, K. Peters, E.-M. Peters, P. Proksch, K. Hostettmann, L. Aké Assi; 5'-O-Demethyldioncophylline A, a New Antimalarial Alkaloid from Triphyophyllum peltatum; Phytochemistry 1998, 49, 1667-1673.

    295)

    G. Bringmann, S. Tasler, H. Endress, K. Peters, E.-M. Peters; Synthesis of Mukonine and Seven Further 1-Oxygenated Carbazole Alkaloids; Synthesis 1998, 1501-1505.

    294)

    G. Bringmann, C. Günther, J. Schlauer, M. Rückert; HPLC-NMR On-Line Coupling  Including the ROESY Technique: Direct Characterization of Naphthylisoquinoline Alkaloids in Crude Plant Extracts; Anal. Chem. 1998, 70, 2805-2811.

    293)

    G. Bringmann, M. Wenzel, M. Rübenacker, M. Schäffer, M. Rückert, L. Aké Assi; Dioncophylline D and 8-O-Methyldioncophylline D, 7,8'-Coupled Naphthylisoquinoline Alkaloids from Triphyophyllum peltatum; Phytochemistry 1998, 49, 1151-1155.

    292)

    E. Urlaub, J. Popp, W. Kiefer, G. Bringmann, D. Koppler, H. Schneider, U. Zimmermann, B. Schrader; FT-Raman investigation of alkaloids in the liana Ancistrocladus heyneanus; Biospectroscopy 1998, 4, 113-120.

    291)

    G. Bringmann, M. Rückert, C. Günther; Identification of Naphthylisoquinoline Alkaloids by LC-NMR on-line Coupling; in Natural Product Analysis (Eds.: P. Schreier, M. Herderich, H.U. Humpf, W. Schwab), Vieweg, Wiesbaden 1998, pp. 147-150.

    290)

    G. Bringmann, S. Busemann; Quantumchemical Calculation of CD Spectra: The Absolute Configuration of Biologically Active Natural Products; in Natural Product Analysis (Eds.: P. Schreier, M. Herderich, H.U. Humpf, W. Schwab), Vieweg, Wiesbaden 1998, pp. 195-212.

    289)

    G. Bringmann, G. François, L. Aké Assi, J. Schlauer; The Alkaloids of Triphyophyllum peltatum (Dioncophyllaceae); Chimia 1998, 52, 18-28.

    288)

    G. Bringmann, A. Ledermann, J. Holenz, M.-T. Kao, U. Busse, H.G. Wu, G. François; Antiplasmodial Activity of Mono- and Dimeric Carbazoles; Planta Med. 1998, 64, 54-57.

    287)

    G. Bringmann, T. Pabst, S. Busemann, K. Peters, E.-M. Peters; Atropo-Enantioselective Synthesis of a Simplified Analog of Mastigophorenes A and B; Tetrahedron 1998, 54, 1425-1438.

    286)

    G. Bringmann, J. Holenz, R. Weirich, M. Rübenacker, C. Funke, M.R. Boyd, R.J. Gulakowski, G. François; First Synthesis of the Antimalarial Naphthylisoquinoline Alkaloid Dioncophylline C, and its Unnatural Anti-HIV Dimer, Jozimine C; Tetrahedron 1998, 54, 497-512.

    285)

    T. Linker, F. Rebien, J. Kraus, G. Bringmann; Kinetic Resolution of Dihydronaphthalenes by Jacobson Epoxidation: Evidence for Polar Intermediates and Structure Elucidation by Calculation of CD Spectra; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, P. Schreier), Vieweg, Braunschweig, 1998, pp. 71-72.

    284)

    C. Fickert, V. Nagel, S. Möller, W. Malisch, R. Stowasser, G. Bringmann, A. Materny, W. Kiefer; Photochemistry Studies by Matrix Isolation Raman Spectroscopy; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, P. Schreier), Vieweg, Braunschweig, 1998, pp. 287-290.

    283)

    W.A. Schenk, T. Beucke, J. Kümmel, F. Servatius, N. Sonnhalter, G. Bringmann, A. Wuzik; Stereo- and Enantioselective Reactions of Thioaldehydes, Thioketones, Thioketenes, and Thionolactones Mediated by Ruthenium Complexes; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, P. Schreier), Vieweg, Braunschweig, 1998, pp. 247-249.

    282)

    G. Bringmann, M. Breuning, S. Busemann, J. Kraus, C. Rummey, R. Stowasser, D. Vitt, W. Kiefer, C. Fickert, T. Linker, F. Rebien, W. Malisch, S. Möller, J. Sundermeyer, G. Wahl; Calculation of Structures, Activities and Spectroscopic Properties of Metal-Activated Molecules; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, P. Schreier), Vieweg, Braunschweig, 1998, pp. 295-296.

    281)

    G. Bringmann, M. Breuning, S. Busemann, J. Hinrichs, T. Pabst, R. Stowasser, S. Tasler, A. Wuzik, W.A. Schenk, J. Kümmel, D. Seebach, G. Jaeschke; Metal-Assisted Synthesis and Application of Axially Chiral Biaryl Systems; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, P. Schreier), Vieweg, Braunschweig, 1998, pp. 141-145.

    280)

    G. Bringmann, J. Holenz, L. Aké Assi, K. Hostettmann; Molluscicidal Activity (Biomphalaria glabrata) of Dioncophylline A - Structure-Activity Investigations; Planta Med. 1998, 64, 485-486.

    279)

    G. Bringmann; Triphyophyllum peltatum and Related African Lianas - Creative Producers of Pharmaceutically Promising Naphthylisoquinoline Alkaloids; in African Genetic Resources for the Development of Pharmaceuticals and Agrochemicals (Ed.: B.M. Abegaz, J.D. Connolly, M.H.H. Nkunya,), University of Dar es Salaam Publications, Dar es Salaam, Tanzania, 1998, pp. 9-32.

    278)

    G. Bringmann, R. Götz, P.A. Keller, R. Walter, M.R. Boyd, F. Lang, A. Garcia, J.J. Walsh, I. Tellitu, K.V. Bhaskar, T.R. Kelly; A Convergent Total Synthesis of the Michellamines; J. Org. Chem. 1998, 63, 1090-1097.

    277)

    G. Bringmann, W. Saeb, G. François, J. Schlauer; Chemical and enzymic syntheses of anti-HIV michellamines and related dimeric naphthylisoquinolines; Pharm. Pharmacol. Lett. 1998, 8, 8-10.

    276)

    G. Bringmann, M. Rückert, M. Wenzel, C. Günther, K. Wolf, J. Holenz, J. Schlauer; Biological activities and biosynthetic origin of acetogenic isoquinoline alkaloids; Pharm. Pharmacol. Lett. 1998, 8, 5-7.

    275)

    G. Bringmann, M. Ochse, M. Herderich, C. Günther, K. Wolf, F. Teltschik, M. Rückert; Isolation and structural elucidation of naphthylisoquinoline alkaloids; Pharm. Pharmacol. Lett. 1998, 8, 1-4.

    274)*

    G. François, G. Bringmann, J.D. Phillipson, M.R. Boyd, G. Timperman, C. Schneider, L. Aké Assi (U.S. Dept. of Health and Human Services); Naphthylisoquinoline Alkaloids, Pharmaceutical Compositions Containing Them and Their Use for the Treatment of Malaria; U.S. Patent Application No. 08/843,582 (16.04.97).

    273)*

    G. Bringmann, M.R. Boyd, R. Götz, T.R. Kelly (U.S. Dept. of Health and Human Services, Trustees of Boston College, USA); Dimeric Arylisoquinoline Alkaloids and Synthesis Method Thereof; U.S. Patent No. 5,786,482; issued 28.07.1998.

    272)*

    G. Bringmann, S. Harmsen, M.R. Boyd (U.S. Dept. of Health and Human Services); Dimeric Naphthylisoquinoline Alkaloids and Synthesis Methods Thereof; U.S. Patent No. 5,789,594; issued 04.08.1998.

    271)*

    G. Bringmann, R. Götz, M.R. Boyd (U.S. Dept. of Health and Human Services); Monomeric Naphthylisoquinoline Alkaloids and Synthesis Methods Thereof; U.S. Patent No. 5,763,613 issued 09.06.1998 US appl. No.08/674,362 (01.07.96).

    270)

    A. Heguy, P. Cai, P. Meyn, D. Houck, S. Russo, R. Michitsch, C. Pearce, B. Katz, G. Bringmann, D. Feineis, D.L Taylor, A.S Tyms; Isolation and characterization of the fungal metabolite 3-O-methylviridicatin as an inhibitor of tumor necrosis factor a-induced human immunodeficiency virus replication; Antiviral Chem. Chemother. 1998, 9, 149-155.

    269)

    G. Bringmann, M. Wenzel, M. Rückert, K. Wolf, S. Busemann, M. Schäffer, L. Aké Assi; Dioncophyllinol D, the First 4-Hydroxylated Naphthylisoquinoline Alkaloid, from the Leaves of Triphyophyllum peltatum; Heterocycles 1998, 47, 985-990.

    268)

    K. Peters, E.-M. Peters, M. Breuning, G. Bringmann; Crystal Structure of 1-ethyl-1-[1-(2-hydroxy-4,6-dimethylphenyl)-2-naphthyl)]propan-1-ol, [C6H2(CH3)2OH][C(OH)(C2H5)2]C10H6; Z. Kristallogr. NCS 1998, 213, 345-346.

    267)

    K. Peters, E.-M. Peters, L. Göbel, G. Bringmann; Crystal Structure of N-tert-Butoxycarbonyl-1-(S)-2-(1-(R)-hydroxyethyl)phenylethylamine, (CH3CHOH)(COOC4H9)C6H4C2H4NH); Z. Kristallogr. NCS 1998, 213, 343-344.

    266)

    K. Peters, E.-M. Peters, O. Schupp, A. Wuzik, G. Bringmann; Crystal Structure of 1-methoxynaphthyl-2-carboxylic acid C10H6(OCH3)COOH; Z. Kristallogr. NCS 1998, 213, 341-342.

    265)

    K. Peters, E.-M. Peters, M. Breuning, O. Schupp, A. Wuzik, G. Bringmann; Crystal Structure of methyl 1-(2-Hydroxy-4,6-dimethylphenyl)naphthyl-2-carboxylate, [(C6H2)(CH3)2OH)](COOCH3)C10H6; Z. Kristallogr. NCS 1998, 213, 339-340.

    264)

    K. Peters, E.-M. Peters, G. Bringmann, B. Schöner; Crystal Structure of (P,Rs)-[1-(2-Hydroxy-4,6-dimethylphenyl)-2-naphthyl]-p-tolylsulfinylmethylketone [(C10H6)(C6H2(CH3)2OH)]COCH2SO(C6H4CH3); Z. Kristallogr. NCS 1998, 213, 337-338.

    263)

    K. Peters, E.-M. Peters, R. Götz, G. Bringmann; Crystal Structure of ethyl 8-bromo-4-acetyloxy-5-isopropoxynaphthalene-2-carboxylate, (OC3H7)(OCOCH3)(OCOC2H5)C10H4Br; Z. Kristallogr. NCS 1998, 213, 333-334.

    262)*

    G. Bringmann, R. Götz, M.R. Boyd, T.R. Kelly; (U.S. Dept. of Health and Human Services; Trustees of Boston College, USA); Synthesis of Arylisoquinoline Alkaloids and Synthesis Methods Thereof; European Patent Application No. 95927269.1; Japanese Patent Application No. 505832/1996; Australian Patent Application No. 31351/95; Canadian Patent Application No. 2,195,646; PCT International Application No. PCT/US 95/09070 (19.07.1995); International Publication No. WO 96/03381 (08.02.1996). Filed: 22.07.94 (Appl.-No. 279,291); 22.07.94 (Appl.-No. 279,339), 13.09.94 (Appl.-No. 305,211), 23.12.94 (Appl.-No. 363,684). U.S. Patent Application No. 363,684 (23.12.1994).

    261)*

    G. Bringmann, S. Harmsen, R. Götz, M.R. Boyd (U.S. Dept. of Health and Human Services); Monomeric and Dimeric Naphthylisoquinoline Alkaloids and Synthesis Methods Thereof; PCT International Patent Application No. PCT/US 95/09132 (19.07.1995); European Patent Application No. 95928091.8; Japanese Patent Application No. 505844/1996; Australian Patent Application No. 31969/95; Canadian Patent Application No. 2,195,647; International Publication No. WO 96/03382 (08.02.1996). Filed: 22.07.1994 (Appl.-No. 279,291) - 22.07.1994 (Appl.-No. 279,339) U.S. Patent Application No. 279,291 (22.07.1994).

    260)

    G. François, C. Diakanamwa, G. Timperman, G. Bringmann, T. Steenackers, G. Atassi, M. van Looveren, J. Holenz, J.-P. Tassin, L. Aké Assi, R. Vanhaelen-Fastré, M. Vanhaelen; Antimalarial and cytotoxic potential of four quassinoids from Hannoa chlorantha and Hannoa klaineana, and their structure-activity relationships; Int. J. Parasitol. 1998, 28, 635-640.

    259)

    G. Bringmann, C. Günther, S. Busemann, M. Schäffer, J.D. Olowokudejo, B. Alo; Ancistroguineines A and B as well as Ancistrotectorine - Naphthylisoquinoline Alkaloids from Ancistrocladus guineënsis; Phytochemistry 1998, 47, 37-43.

    258)

    G. Bringmann, F. Teltschik, M. Schäffer, R. Haller, S. Bär, M.A. Robertson, M. Isahakia; Ancistrobertsonine A and Related Naphthylisoquinoline Alkaloids from Ancistrocladus robertsoniorum; Phytochemistry 1998, 47, 31-35.

    257)

    J. Schlauer, M. Rückert, B. Wiesen, M. Herderich, L. Aké Assi, R.D. Haller, S. Bär, K.-U. Fröhlich, G. Bringmann; Characterization of Enzymes from Ancistrocladus (Ancistrocladaceae) and Triphyophyllum (Dioncophyllaceae) Catalyzing Oxidative Coupling of Naphthylisoquinoline Alkaloids to give Michellamines; Arch. Biochem. Biophys. 1998, 350, 87-94.

    1997

    256)*

    M.R. Boyd, J.H. Cardellina II, K.P. Manfredi, J.W. Blunt, L.K. Pannell, J.B. McMahon, R.J. Gulakowski, G.M. Cragg, G. Bringmann, D. Thomas, J. Jato (U.S. Dept. of Health and Human Services); Process of Preparing Michellamine Compounds; U.S. Patent No. 5,654,432; issued 05.08.1997.

    255)

    M. Meininger, P.M. Jakob, M. von Kienlin, D. Koppler, G. Bringmann, A. Haase; Radial Spectroscopic Imaging; J. Magn. Reson. 1997, 125, 325-331.

    254)

    K. Krohn, K. Beckmann, U. Flörke, H.-J. Aust, S. Draeger, B. Schulz, S. Busemann, G. Bringmann; New Palmarumycins CP4a and CP5 from Coniothyrium palmarum: Structure Elucidation, Crystal Structure Analysis and Determination of the Absolute Configuration by CD Calculations; Tetrahedron 1997, 53, 3101-3110.

    253)

    B.W. Nugroho, B. Güssregen, V. Wray, L. Witte, G. Bringmann, P. Proksch; Insecticidal Rocaglamide Derivatives from Aglaia elliptica and A. harmsiana; Phytochemistry 1997, 45, 1579-1585.

    252)

    G. Bringmann, M. Ochse, M. Schäffer, R. God, R. Walter, G. François; N,N-Dimethyldioncophyllinium A Iodide - Synthesis, Stereoanalysis, and Antimalarial Activity of the First N-Quaternary Naphthylisoquinolinium Salt; Planta Med. 1997, 63, 544-547.

    251)

    Y.F. Hallock, J.H. Cardellina II, M. Schäffer, M. Stahl, G. Bringmann, G. François, M.R. Boyd; Yaoundamines A and B, New Antimalarial Naphthylisoquinoline Alkaloids from Ancistrocladus korupensis; Tetrahedron 1997, 53, 8121-8128.

    250)

    G. Bringmann, D. Feineis, C. Grote, R. God, H.W. Clement, K.-H. Sontag, B. Janetzky, H. Reichmann, W.-D. Rausch, P. Riederer, W. Wesemann; Highly Halogenated Tetrahydro-ß-Carbolines as a New Class of Dopaminergic Neurotoxins; in Pharmacology of Endogenous Neurotoxins (Ed.: A. Moser), Birkhäuser, Boston, Basel, Berlin, 1998, pp. 151-169.

    249)

    G. François, G. Timperman, W. Eling, L. Aké Assi, J. Holenz, G. Bringmann; Naphthylisoquinoline alkaloids against malaria: evaluation of the curative potential of dioncophylline C and dioncopeltine A against Plasmodium berghei in vivo; Antimicrob. Agents Chemother. 1997, 41, 2533-2539.

    248)

    G. Bringmann, J. Holenz, B. Wiesen, B. W. Nugroho, P. Proksch; Dioncophylline A as a Growth-Retarding Agent against the Herbivorous Insect Spodoptera littoralis: Structure-Activity Relationships; J. Nat. Prod. 1997, 60, 342-347.

    247)

    D. Seebach, G. Jaeschke, K. Gottwald, K. Matsuda, R. Formisano, D.A. Chaplin, M. Breuning, G. Bringmann; Resolution of Racemic Carboxylic Acid Derivatives by Ti-TADDOLate Mediated Esterification Reactions - A General Method for the Preparation of Enantiopure Compounds; Tetrahedron 1997, 53, 7539-7556.

    246)

    G. Bringmann, T. Mader, D. Feineis; Determination of Viridicatin in Penicillium cyclopium by Capillary Gas Chromatography; Anal. Biochem. 1997, 253, 18-25.

    245)

    G. Bringmann, S. Busemann, K. Krohn, K. Beckmann; Quantumchemical Calculation of CD Spectra: the Absolute Configuration of Palmarumycins CP3 and C2; Tetrahedron 1997, 53, 1655-1664.

    244)

    Y.F. Hallock, K.P. Manfredi, J.-R. Dai, J.H. Cardellina II, R.J. Gulakowski, J.B. McMahon, M. Schäffer, M. Stahl, K.-P. Gulden, G. Bringmann, G. François, M.R. Boyd; Michellamines D-F, New HIV-Inhibitory Dimeric Naphthylisoquinoline Alkaloids, and Korupensamine E, a New Antimalarial Monomer, from Ancistrocladus korupensis; J. Nat. Prod. 1997, 60, 677-683.

    243)

    G. Bringmann, R. Stowasser, L. Göbel; DF-studies on a 'stop and go' rotor: steric and electronic factors determining the regio- and stereochemical position of a h6-Cr(CO­)­3 metal fragment on a helically distorted biaryl ligand; J. Organomet. Chem. 1997, 544, 7-13.

    242)

    G. François, G. Timperman, T. Steenackers, L. Aké Assi, J. Holenz, G. Bringmann; In vitro inhibition of liver forms of the rodent malaria parasite Plasmodium berghei by naphthylisoquinoline alkaloids - structure-activity relationships of dioncophyllines A and C, and ancistrocladine; Parasitol. Res. 1997, 83, 673-679.

    241)

    G. Bringmann, A. Wuzik, O. Schupp, K. Peters, E.-M. Peters; 1,3-Di-tert-butyl-6H-benzo[b]naphtho[1,2-d]pyran-6-thione, a Severely Helically Distorted Thionolactone-Bridged Biaryl; Z. Naturforsch. 1997, 52b, 355-358.

    240)

    M. Meininger, R. Stowasser, P.M. Jakob, H. Schneider, D. Koppler, G. Bringmann, U. Zimmermann, A. Haase; Nuclear Magnetic Resonance Microscopy of Ancistrocladus heyneanus; Protoplasma 1997, 198, 210-217.

    239)

    N.H. Anh, A. Porzel, H. Ripperger, G. Bringmann, M. Schäffer, R. God, T.V. Sung, G. Adam; Naphthylisoquinoline Alkaloids from Ancistrocladus cochinchinensis; Phytochemistry 1997, 45, 1287-1291.

    238)

    H. Lanig, M. Hof, G. Bringmann, F.W. Schneider; Time-resolved fluorescence spectroscopy of helically distorted aromatic systems; Chem. Phys. Lett. 1997, 272, 478-483.

    237)

    K. Krohn, K. Beckmann, H.-J. Aust, S. Draeger, B. Schulz, S. Busemann, G. Bringmann; Generation of the Palmarumycin Spiroacetal Framework by Oxidative Cyclization of an Open Chain Metabolite from Coniothyrium palmarum; Liebigs Ann. 1997, 2531-2534.

    236)

    G. François, T. Steenackers, G. Timperman, L. Aké Assi, R.D. Haller, S. Bär, M.A. Isahakia, S.A. Robertson, C. Zhao, N.J. De Souza, J. Holenz, G. Bringmann; Retarded Development of Exoerythrocytic Stages of the Rodent Malaria Parasite Plasmodium berghei in Human Hepatoma Cells by Extracts from Dioncophyllaceae and Ancistrocladaceae Species; Int. J. Parasitol. 1997, 27, 29-32.

    235)

    G. Bringmann, W. Saeb, L. Aké Assi, G. François, A.S. Sankara Narayanan, K. Peters, E.-M. Peters; Betulinic Acid: Isolation from Triphyophyllum peltatum and Ancistrocladus heyneanus, Antimalarial Activity, and Crystal Structure of the Benzyl Ester; Planta Med. 1997, 63, 255-257.

    234)

    G. Bringmann, D. Koppler, D. Scheutzow, A. Porzel; Determination of Configuration at the Biaryl Axes of Naphthylisoquinoline Alkaloids by Long-Range NOE Effects; Magn. Reson. Chem. 1997, 35, 297-301.

    233)

    G. Bringmann, J. Hinrichs; Efficient Kinetic Resolution of a Racemic 7-Membered Biaryl Lactone: Enantioselective Synthesis of 2,2'-Dihydroxymethyl-1,1'-binaphthyl; Tetrahedron: Asymmetry 1997, 8, 4121-4126.

     

    232)

    G. Bringmann, W. Saeb, K. Peters, E.-M. Peters; The Absolute Stereostructure of Dioncophylline A by Anomalous X-ray Dispersion of a 5-Bromo Derivative; Phytochemistry 1997, 45, 1283-1285.

    231)

    G. Bringmann, F. Pokorny, M. Wenzel, K. Wurm, C. Schneider; Labelled Precursors for Biosynthetic Studies on Naphthylisoquinoline Alkaloids; J. Lab. Compd. Radiopharm. 1997, 39, 29-38.

    230)

    G. François, G. Timperman, R.D. Haller, S. Bär, M.A. Isahakia, S.A. Robertson, C. Zhao, N.J. De Souza, L. Aké Assi, J. Holenz, G. Bringmann; Growth Inhibition of Asexual Erythrocytic Forms of Plasmodium falciparum and P. berghei in vitro by Naphthylisoquinoline Alkaloid-Containing Extracts of Ancistrocladus and Triphyophyllum Species; Int. J. Pharmacognosy 1997, 35, 55-59.

    229)

    G. Bringmann, M. Stahl, K.-P. Gulden; Circular Dichroism of Naphthyldihydroisoquinoline Alkaloids: Determination of the Axial Configuration of Yaoundamine A; Tetrahedron 1997, 53, 2817-2822.

    1996

    228)

    G. Bringmann; African plants as sources of pharmacologically exciting biaryl and quateraryl alkaloids; in Chemistry, Biological and Pharmacological Properties of African Medicinal Plants (Eds.: K. Hostettmann, F. Chinyanganya, M. Maillard, J.-L. Wolfender), University of Zimbabwe Publications, Harare, Zimbabwe, 1996, pp. 1-19.

    227)

    G. Bringmann, J. Holenz, L. Aké Assi, T. Steenackers, G. François; Eine potentielle neue Generation von pflanzlichen Wirkstoffen gegen Malaria; Blick - Forschung, Lehre, Dienstleistung (Universität Würzburg) 1996, 85-87.

    226)

    G. Bringmann, R. Götz, S. Harmsen, J. Holenz, R. Walter; Biomimetic Total Synthesis of Michellamines A-C; Liebigs Ann. 1996, 2045-2058.

    225)

    P. Chau, I.R. Czuba, M.A. Rizzacasa, G. Bringmann, K.-P. Gulden, M. Schäffer; Convergent Synthesis of Naphthylisoquinoline Alkaloids: Total Synthesis of (+)-O-Methylancistrocline; J. Org. Chem. 1996, 61, 7101-7105.

    224)

    G. Bringmann, O. Schupp; Der gezielte Aufbau "chiraler Achsen"; Blick - Forschung, Lehre, Dienstleistung (Universität Würzburg) 1996, 72-74.

    223)

    G. Bringmann, R. Götz, G. François; Synthesis of Pindikamine A, a Michellamine-Related Dimer of a Non-Natural, 'Skew' Naphthylisoquinoline; Tetrahedron 1996, 52, 13419-13426.

    222)

    G. Bringmann, W. Saeb, D. Koppler, G. François; Jozimine A ('Dimeric' Dioncophylline A), A Non-Natural Michellamine Analog with High Antimalarial Activity; Tetrahedron 1996, 52, 13409-13418.

    221)

    G. Bringmann, R. Stowasser; Structures, Energetics, and Dynamics of Transition Metal-Activated Lactone-Bridged Biaryl Complexes: a Density-Functional Study; J. Mol. Mod. 1996, 2, 268-269.

    220)

    G. Bringmann, D. Feineis; Biologisch aktive Naturstoffe aus tropischen Lianen; Blick - Forschung, Lehre, Dienstleistung (Universität Würzburg) 1996, 45-49.

    219)

    G. Bringmann, J. Holenz, L. Aké Assi, C. Zhao, K. Hostettmann; Molluscicidal Activity of Naphthylisoquinoline Alkaloids from Triphyophyllum and Ancistrocladus Species; Planta Med. 1996, 62, 556-557.

    218)

    G. François, M. Van Looveren, G. Timperman, B. Chimanuka, L. Aké Assi, J. Holenz, G. Bringmann; Larvicidal activity of the naphthylisoquinoline alkaloid dioncophylline A against the malaria vector Anopheles stephensi; J. Ethnopharmacol. 1996, 54, 125-130.

    217)

    G. Bringmann, D. Koppler, B. Wiesen, G. François, A.S. Sankara Narayanan, M.R. Almeida, H. Schneider, U. Zimmermann; Ancistroheynine A, the First 7,8'-Coupled Naphthylisoquinoline Alkaloid from Ancistrocladus heyneanus; Phytochemistry 1996, 43, 1405-1410.

    216)

    G. Bringmann, R. God, M. Schäffer; An Improved Degradation Procedure for Determination of the Absolute Configuration in Chiral Isoquinoline and ß-Carboline Derivatives; Phytochemistry 1996, 43, 1393-1403.

    215)

    G. Bringmann, R. Stowasser, D. Vitt; Local and non-local DF calculation of the structure of the helically twisted 1,3-dimethyl-{(h6-chromium-tricarbonyl)benzo}[b]naphtho[1,2-d]pyran-6-one: a comparison; J. Organomet. Chem. 1996, 520, 261-264.

    214)

    J. Hartung, R. Stowasser, D. Vitt, G. Bringmann; 5-exo or 6-endo? Exploring Transition State Structures in Cyclizations of 4-Penten-1-oxyl Radicals; Angew. Chem. 1996, 108, 3056-3059; Angew. Chem. Int. Ed. Engl. 1996, 35, 2820-2823.

    213)

    K.-H. Sontag, C. Heim, T.A. Sontag, W. Kolasiewicz, W. Clement, C. Grote, W. Wesemann, B. Janetzky, H. Reichmann, D. Feineis, R. God, G. Bringmann, D. Rausch, M. Abdel-mohsen, M. Abdel-moneim, W.W. Chan, E. Koutsilieri, B. Zielke, M. Götz, W. Gsell, P. Riederer; Progressive neurodegeneration of the dopaminergic system and inhibition of the complex I induced by the chloral-derived tetrahydro-ß-carboline TaClo; in The Basal Ganglia V (Eds.: C. Ohye, M. Kimura, J.S. McKenzie), Plenum Press, New York and London, 1996, pp. 387-394.

    212)

    G. Bringmann, M. Wenzel, H. Bringmann, J. Schlauer, L. Aké Assi; Die "Teilzeit-fleischfressende" Pflanze Triphyophyllum peltatum (Dioncophyllaceae): Nutzung der Fangorgane zur Erforschung der Alkaloidbildung; Der Palmengarten 1996, 60, 32-37.

    211)

    G. François, L. Aké Assi, J. Holenz, G. Bringmann; Constituents of Picralima nitida display pronounced inhibitory activities against asexual erythrocytic forms of Plasmodium falciparum in vitro; J. Ethnopharmacol. 1996, 54, 113-117.

    210)

    G. Bringmann; Mono- and Dimeric Naphthylisoquinoline Alkaloids - Pharmaceutically and Structurally Exciting Natural Heterocycles with Axial Chirality; Bull. Soc. Chim. Belg. 1996, 105, 601-613.

    1995-1991

    209)

    G. Bringmann, A. Ledermann, M. Stahl, K.-P. Gulden; Bismurrayaquinone A: Synthesis, Chromatographic Enantiomer Resolution, and Stereoanalysis by Computational and Experimental CD Investigations; Tetrahedron 1995, 51, 9353-9360.

    208)

    G. Bringmann; Michellamine – Neue antivirale Alkaloide aus afrikanischen Pflanzen; in Phytopharmaka in Forschung und klinischer Anwendung (Eds.: N. Rietbrock, D. Loew), Verlag Steinkopff, Darmstadt, 1995, pp. 113-128.

    207)

    K.-H. Sontag, C. Heim, T.A. Sontag, R. God, H. Reichmann, W. Wesemann, W.-D. Rausch, P. Riederer, G. Bringmann; Long-term behavioural effects of TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline) after subchronic treatment in rats; J. Neural Transm. 1995, 46 [Suppl.], 283-289.

    206)

    C. Grote, H.-W. Clement, W. Wesemann, G. Bringmann, D. Feineis, P. Riederer, K.-H. Sontag; Biochemical lesions of the nigrostriatal system by TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline) and derivatives; J. Neural Transm. 1995, 46 [Suppl.], 275-281.

    205)

    B. Janetzky, R. God, G. Bringmann, H. Reichmann; 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline, a new inhibitor of complex I; J. Neural Transm. 1995, 46 [Suppl.], 265-273.

    204)

    W.-D. Rausch, M. Abdel-mohsen, E. Koutsilieri, W.W. Chan, G. Bringmann; Studies of the potentially endogenous toxin TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline) in neuronal and glial cell cultures; J. Neural Transm. 1995, 46 [Suppl.], 255-263.

    203)

    G. Bringmann, R. God, D. Feineis, B. Janetzky, H. Reichmann; TaClo as a neurotoxic lead: improved synthesis, stereochemical analysis, and inhibition of the mitochondrial respiratory chain; J. Neural Transm. 1995, 46 [Suppl.], 245-254.

    202)

    G. Bringmann, R. God, D. Feineis, W. Wesemann, P. Riederer, W.-D. Rausch, H. Reichmann, K.-H. Sontag; The TaClo concept: 1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo), a new toxin for dopaminergic neurons; J. Neural Transm. 1995, 46 [Suppl.], 235-244.

    201)

    Y.F. Hallock, J.H. Cardellina II, T. Kornek, K.-P. Gulden, G. Bringmann, M.R. Boyd; Gentrymine B, the First Quaternary Isoquinoline Alkaloid from Ancistrocladus korupensis; Tetrahedron Lett. 1995, 36, 4753-4756.

    200)

    G. Bringmann, T. Mader; In vivo formation of diazepam-like 1,4-benzodiazepines by Penicillium verrucosum var. verrucosum after administration of 2-aminobenzophenones and glycine; J. Neural Transm. 1995, 101, 169-181.

    199)

    G. Bringmann, D. Feineis, R. God, S. Fähr, W. Wesemann, H.-W. Clement, C. Grote, W. Kolasiewicz, K.-H. Sontag, C. Heim, T.A. Sontag, H. Reichmann, B. Janetzky, W.-D. Rausch, M. Abdel-mohsen, E. Koutsilieri, M.E. Götz, W. Gsell, B. Zielke, P. Riederer; Neurotoxic effects on the dopaminergic system induced by TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline), a potential mammalian alkaloid: in vivo and in vitro studies; Biogenic Amines 1996, 12, 83-102.

    198)

    J. Lange, H. Burzlaff, G. Bringmann, O. Schupp; Determination of the Absolute Stereostructure of a Helical Biaryl Lactone by Multiple Scattering X-Ray Experiments; Tetrahedron 1995, 51, 9361-9366.

    197)

    G. Bringmann, R. Walter, R. Weirich; Synthesis of Axially Chiral Compounds, Part B.2.: Biaryls; in Methods of Organic Chemistry (Houben Weyl) 4th ed. (Eds.: G. Helmchen, R.W. Hoffmann, J. Mulzer, E. Schaumann), vol. E 21a, Thieme, Stuttgart, 1995, pp. 567-587.

    196)

    G. Bringmann, H. Busse, U. Dauer, S. Güssregen, M. Stahl; Structure and Enantiomerization of Helically Twisted Lactone-Bridged Biaryls: a Theoretical Study; Tetrahedron 1995, 51, 3149-3158.

    195)

    G. François, G. Timperman, J. Holenz, L. Aké Assi, T. Geuder, L. Maes, J. Dubois, M. Hanocq, G. Bringmann; Naphthylisoquinoline alkaloids exhibit strong growth-inhibiting activities against Plasmodium falciparum and P. berghei in vitro  - Structure-activity relationships of dioncophylline C; Ann. Trop. Med. Parasitol. 1996, 90, 115-123.

    194)

    G. Bringmann, H. Friedrich, G. Birner, M. Koob, K.-H. Sontag, C. Heim, W. Kolasiewicz, S. Fähr, M. Stäblein, R. God, D. Feineis; Determination of the dopaminergic neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo) in biological samples using gas chromatography with selected ion monitoring; J. Chromatogr. B, 1996, 687, 337-348.

    193)

    K. Peters, E.-M. Peters, G. Bringmann, T. Mader; 5-Bromo-2-(chloroacetamido)-benzophenone - a Synthetic Precursor to 6-Bromoviridicatin; Z. Naturforsch. 1996, 51b, 754-755.

    192)

    G. Bringmann, S. Harmsen, O. Schupp, R. Walter; Metal Assisted "Twisting" of Axes: A Novel Approach to Stereoselective Biaryl Synthesis; in Stereoselective Reactions of Metal-Activated Molecules (Eds.: H. Werner, J. Sundermeyer), Vieweg, Braunschweig, 1995, pp. 137-142.

    191)*

    G. Bringmann, W. Wesemann, K.-H. Sontag, P. Riederer, W.-D. Rausch, D. Feineis,  R. God, H.-W. Clement, C. Grote, W. Gsell, M.E. Götz, B. Zielke; Verwendung halogenierter ß-Carboline als Modellsubstanzen zur Erzeugung neurodegenerativer Erkrankungen; German Patent DE 44 42 097 C2, issued 09.04.98; PCT International patent Application PCT/DE 95/01675 (27.11.1995); European Patent application No. 95 936 988.5; International Publication No. WO 96/16651 (06.06.1996).

    190)

    R. Pikl, W. Kiefer, I. Reuther, W.A. Schenk, B. Schöner, O. Schupp, G. Bringmann; Synthesis and vibrational spectra of thiobutyrolactone and thiono-benzonaphtho-pyranones and their cyclopentadienyl ruthenium complexes; J. Organomet. Chem. 1995, 494, 89-93.

    189)

    K. Peters, E.-M. Peters, G. Bringmann, P.A. Keller, M. Schäffer; (1R,3R)-1,3-Dimethyl-8-hydroxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline Hydrochloride - an Enantiomerically Pure Building Block for the Synthesis of Naphthylisoquinoline Alkaloids; Z. Naturforsch. 1995, 50b, 1137-1139.

    188)

    G. Bringmann, U. Dauer, M. Lankers, J. Popp, U. Posset, W. Kiefer; Structural and electronic influence of aluminum trichloride on a benzonaphthopyranone; J. Mol. Struct. 1995, 349, 431-434.

    187)

    G. Bringmann, D. Vitt; Stereoselective Ring-Opening Reaction of Axially Prostereogenic Biaryl Lactones with Chiral Oxazaborolidines: An AM1 Study of the Complete Mechanistic Course; J. Org. Chem. 1995, 60, 7674-7681.

    186)

    Y.F. Hallock, C.B. Hughes, J.H. Cardellina II, M. Schäffer, K.-P. Gulden, G. Bringmann, M.R. Boyd; Dioncophylline A, the Principal Cytotoxin from Ancistrocladus letestui; Nat. Prod. Lett. 1995, 6, 315-320.

    185)

    G. Bringmann, C. Hesselmann, D. Feineis; Analysis of glyoxylate-derived 1,3-thiazolidines and their precursors after trimethylsilylation by gas chromatography - mass spectrometry; J. Chromatogr. A 1995, 707, 267-281.

    184)

    G. Bringmann, U. Dauer; The Influence of Lewis Acids on Structure and Dynamics of Lactone-Bridged Biaryls: Quantumchemical Studies; J. Mol. Model. 1995, 1, 88.

    183)*

    G. Bringmann, H. Reichmann, D. Feineis, R. God, B. Janetzky; Halogenierte ß-Carbolin-Derivate, Verfahren zu ihrer Herstellung und Verwendung dieser Substanzen zur Hemmung der Atmungskette; German patent D.O.S. DE 44 36 190 A1, disclosure 11.04.96; PCT International Patent Application No. PCT/DE 95/01403 (10.10.95); European Patent Application No. 95 935 329.3; International Publication No. WO 96/11197 (18.04.1996).

    182)

    K. Peters, E.-M. Peters,  G. Bringmann, O. Schupp; 1,3-Dimethoxy-6H-benzo[b]naphtho-[1,2-d]pyran-6-thione, a Thionolactone-Bridged Axially Prostereogenic Biaryl; Z. Naturforsch. 1996, 51b, 431-432.

    181)

    K. Peters, E.-M. Peters, G. Bringmann, S. Harmsen; 1,4-Dibromonaphthalene-2,3-diyl-bis(1'-bromo-2'-naphthoate).CHCl3, a Potential Precursor to Lactone-Bridged Teraryls; Z. Naturforsch. 1996, 51b, 144-146.

    180)

    G. Bringmann, F. Pokorny; The Naphthylisoquinoline Alkaloids; in The Alkaloids, vol. 46, (Ed.: G.A. Cordell), Academic Press, New York, 1995, pp. 127-271.

    179)

    K. Peters, E.-M. Peters, G. Bringmann, R. God; 2-Trifluoroacetyl-1-methyl-1,2,3,4-tetrahydro-ß-carboline, a Gaschromatographically Useful Derivative of the Mammalian Alkaloid Eleagnine; Z. Naturforsch. 1995, 50b, 1564-1565.

    178)*

    G. Bringmann, M.R. Boyd, R. Götz, T.R. Kelly; (U.S. Dept. of Health and Human Services; Trustees of Boston College, USA); Dimeric Arylisoquinoline Alkaloid Compounds; U.S. Patent No. 5,578,729; issued 26.11.1996. Filed: 23.12.94 (Appl.-No. 363,684).

    177)*

    G. Bringmann, S. Harmsen, M.R. Boyd (U.S. Dept. of Health and Human Services); Dimeric Naphthylisoquinoline Alkaloids and Synthesis Methods Thereof; U.S. Patent No. 5,571,919; issued 05.11.1996. Filed: 22.07.1994 (Appl.-No. 279,339).

    176)*

    G. Bringmann, R. Götz, M.R. Boyd (U.S. Dept. of Health and Human Services); Monomeric Naphthylisoquinoline Alkaloids and Synthesis Methods Thereof; U.S. Patent No. 5,552,550; issued 03.09.1996. Filed: 22.07.1994 (Appl.-No. 279,291).

    175)

    T.R. Kelly, A. Garcia, F. Lang, J.J. Walsh, K.V. Bhaskar, M.R. Boyd, R. Götz, P.A. Keller, R. Walter, G. Bringmann; Convergent Total Synthesis of the Michellamines; Tetrahedron Lett. 1994, 35, 7621-7624.

    174)

    G. Bringmann, K.-P. Gulden, D. Vitt, K. Birken, C. Helf; AdaptivSearch: A novel iterative algorithm for the generation of n-dimensional hypersurfaces using an adaptive numerical strategy; J. Mol. Model. 1995, 1, 161-175.

    173)

    G. Bringmann, M. Gassen, R. Lardy; 4-Hydroxynon-2-enal, a Cytotoxic Lipid Peroxidation Product, and its C5-Analog 4-Hydroxypent-2-enal: Enantioselective Synthesis and Stereoanalysis; Tetrahedron 1994, 50, 10245-10252.

    172)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, R. Götz, P.A. Keller, C. Michel; Crystal structure of 1-(4,6-dimethoxy-2-methylphenyl)-naphthalene; Z. Kristallogr. 1995, 210, 292-293.

    171)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, C. Kehr, R.D. Haller, S. Bär, M.A. Isahakia, S.A. Robertson; Crystal structure of droserone in 'biogenic crystals' found under the stem bark of Ancistrocladus robertsoniorum; Z. Kristallogr. 1995, 210, 290-291.

    170)

    G. Bringmann, S. Harmsen, J. Holenz, T. Geuder, R. Götz, P.A. Keller, R. Walter, Y.F. Hallock, J.H. Cardellina II, M.R. Boyd; 'Biomimetic' Oxidative Dimerization of Korupensamine A: Completion of the First Total Synthesis of Michellamines A, B, and C; Tetrahedron 1994, 50, 9643-9648.

    169)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, O. Schupp; Crystal structure of phenyl 1-hydroxy-2-naphthoate, an unexpected product from an attempted aryl aryl coupling reaction; Z. Kristallogr. 1995, 210, 210-211.

    168)

    G. Bringmann, A. Ledermann, G. François; Dimeric Murrayafoline A, a Potential Bis-Carbazole Alkaloid: 'Biomimetic' Synthesis, Atropoisomer Separation, and Antimalarial Activity; Heterocycles 1995, 40, 293-300.

    167)

    G. Bringmann, R. Götz, P.A. Keller, R. Walter, P. Henschel, M. Schäffer, M. Stäblein, T.R. Kelly, M.R. Boyd; First Total Synthesis of Korupensamines A and B; Heterocycles 1994, 39, 503-512.

    166)

    Y.F. Hallock, K.P. Manfredi, J.W. Blunt, J.H. Cardellina II, M. Schäffer, K.-P. Gulden, G. Bringmann, A.Y. Lee, J. Clardy, G. François, M.R. Boyd; Korupensamines A-D, Novel Antimalarial Alkaloids from Ancistrocladus korupensis; J. Org. Chem. 1994, 59, 6349-6355.

    165)

    G. Bringmann, K.-P. Gulden, Y.F. Hallock, K.P. Manfredi, J.H. Cardellina II, M.R. Boyd, B. Kramer, J. Fleischhauer; Circular Dichroism of Michellamines: Independent Assignment of Axial Chirality by Calculated and Experimental CD Spectra; Tetrahedron 1994, 50, 7807-7814.

    164)

    M.R. Boyd, Y.F. Hallock, J.H. Cardellina II, K.P. Manfredi, J.W. Blunt, J.B. McMahon, R.W. Buckheit, Jr., G. Bringmann, M. Schäffer, G.M. Cragg, D.W. Thomas, J.G. Jato; Anti-HIV Michellamines from Ancistrocladus korupensis; J. Med. Chem. 1994, 37, 1740-1745.

    163)*

    G. François, G. Bringmann, J.D. Phillipson, M.R. Boyd, L. Aké Assi, C. Schneider, G. Timperman (U.S. Dept. of Health and Human Services); Antimalarial Naphthylisoquinoline Alkaloids and Pharmaceutical and Medical Uses Thereof; ; U.S. Patent No. 5,639,761; issued 17.06.1997; PCT International Patent Application No. PCT/US 95/01717 (13.02.1995); European Patent Application No. 95910230.2; Japanese Patent Application No. 521360/1995; Australian Patent Application No. 18417/95; Canadian Patent Application No. 2,185,155; International Publication No. WO 95/21616 (17.08.1995). U.S. Patent Application No. 195,547 (14.02.1994). Filed: 14.02.1994 (Appl.-No. 195,547) Chemical Abstracts 1995, 123, 266123u.

    162)*

    M.R. Boyd, G. François, G. Bringmann, Y.F. Hallock, K.P. Manfredi, J.H. Cardellina II (U.S. Dept. of Health and Human Services); Antimalarial Korupensamines and Pharmaceutical Compositions and Medical Uses Thereof; U.S. Patent No. 5,409,938; issued 25.04.1995; Japanese Patent Application No. 521405/1995; Australian Patent Application No. 17476/1996; PCT International Patent Application No. PCT/US 95/01853 (13.02.1995); International Publication No. WO 95/21826 (26.08.1995). Filed: 14.02.1994 (Appl.-No. 195,260) Chemical Abstracts 1995, 123, 40928y.

    161)

    G. Bringmann, O. Schupp; Stereocontrolled 'twisting' of biaryl systems – a new pathway to axial chirality; S. Afr. J. Chem. 1994, 47, 83-102.

    160)

    G. Bringmann, P.A. Keller, K. Rölfing; A New Approach to Atropselective Biaryl Synthesis, Utilizing Chiral Carbon-Carbon Bridges; Synlett 1994, 423-424.

    159)

    G. François, G. Bringmann, C. Dochez, C. Schneider, G. Timperman, L. Aké Assi; Activities of extracts and naphthylisoquinoline alkaloids from Triphyophyllum peltatum, Ancistrocladus abbreviatus and Ancistrocladus barteri against Plasmodium berghei (Anka strain) in vitro; J. Ethnopharmacol. 1995, 46, 115-120.

    158)

    G. Bringmann, T. Geuder, S. Harmsen; An Efficient One-Pot Synthesis of 1,4-Diacyl-2,3,5,6-Tetramethoxybenzenes via Biscuprated Precursors; Synthesis 1994, 1143-1145.

    157)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, O. Schupp; Crystal structure of 1-isopropyl-4-methyl-6H-benzo[b]-naphtho[1,2-d]pyran-6-one - a configuratively labile, but enantiomerically pure crystallizing helicene-like bridged biaryl; Z. Kristallogr. 1995, 210, 49-50.

    156)

    G. Bringmann, L. Göbel, K. Peters, E.-M. Peters, H.G. von Schnering; Synthesis, structure, dynamics, and first atropisomer-selective cleavage of the chromium tricarbonyl complex of a lactone-bridged biaryl; Inorg. Chim. Acta 1994, 222, 255-260.

    155)

    G. Bringmann, U. Dauer, O. Schupp, M. Lankers, J. Popp, U. Posset, A. Weippert, W. Kiefer; The influence of aluminum trichloride on a configuratively labile lactone-bridged biaryl: quantum chemical calculations and optical spectroscopy; Inorg. Chim. Acta 1994, 222, 247-253.

    154)

    G. Bringmann, R.D. Haller, S. Bär, M.A. Isahakia, S.A. Robertson; Ancistrocladus robertsoniorum J. Léonard: eine erst spät entdeckte Ancistrocladus-Art; Der Palmengarten 1994, 58, 148-153.

    153)

    G. Bringmann, B. Schöner, K. Peters, E.-M. Peters, H.G. von Schnering; Synthesis and Structure of a Protected Lactolate-Bridged Biaryl with Relevance to the Atropisomer-Selective Ring Opening of Biaryl Lactones; Liebigs Ann. Chem. 1994, 439-444.

    152)

    G. Bringmann, T. Hartung; Synthesis and Enantiomerization of a Nonracemic 2-Hydroxy-2'-biphenylcarbaldehyde, a Probable Intermediate in the Atropo-Enantioselective Ring Opening of Biaryl Lactones; Liebigs Ann. Chem. 1994, 313-316.

    151)

    G. Bringmann, M. Rübenacker, W. Koch, D. Koppler, T. Ortmann, M. Schäffer, L. Aké Assi; 5'-O-Demethyl-8-O-methyl-7-epi-dioncophylline A and Its 'Regularly' Configurated Atropisomer from Triphyophyllum peltatum; Phytochemistry 1994, 36, 1057-1061.

    150)

    G. Bringmann, M. Gassen, S. Schneider; Sensitive, gas chromatography-based stereoanalysis of 4-hydroxyalkenals, toxic products of lipid peroxidation; J. Chromatogr. A 1994, 670, 153-160.

    149)

    P. Riederer, G. Bringmann, K. Jellinger, W.-D. Rausch, H. Reichmann, K.-H. Sontag, W. Wesemann; Neurotoxine und Neuroprotektion: Membranabhängige radikalische Prozesse - Bedeutung für die Ätiologie und Therapie des Parkinson-Syndroms; in Materialien zur Gesundheitsforschung, Schriftenreihe zum Programm der Bundesregierung Gesundheit 2000 (Ed.: Projektträgerschaft "Forschung im Dienste der Gesundheit"), Verlag für neue Wissenschaft GmbH, Bremerhaven, 1995, pp. 139-157.

    148)

    G. Bringmann, D. Koppler, A. Porzel, D. Scheutzow; Aufklärung der Achsenkonfiguration an Naphthylisochinolin-Alkaloiden mit Hilfe der Hochauflösungs-NMR-Spektroskopie; GIT Fachz. Lab. 1994, 38, 705-706.

    147)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, D. Leimkötter; Crystal structure of racemic trans-2-(4-methylphenyl)-cyclohexyl chloroacetate; Z. Kristallogr. 1994, 209, 979-980.

    146)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, R. God; Crystal structure of 2-methyl-1-(1-methylethyl)-quinolinium iodide; Z. Kristallogr. 1995, 210, 34-35.

    145)

    G. Bringmann, T. Hartung, O. Kröcher, K.-P. Gulden, J. Lange, H. Burzlaff; Synthesis and Absolute Stereostructure of Dinaphth[2,1-c:1',2'-e]oxepin-3-(5H)-one; Tetrahedron 1994, 50, 2831-2840.

    144)

    G. Bringmann, B. Schöner, O. Schupp, W.A. Schenk, I. Reuther, K. Peters, E.-M. Peters, H.G. von Schnering; Synthesis and ring-opening reactions of cationic ruthenium biaryl thionolactone complexes; J. Organomet. Chem. 1994, 472, 275-284.

    143)

    G. Bringmann, B. Schöner, O. Schupp, K. Peters, E-M. Peters, H.G. von Schnering; Synthesis, Optical Resolution, and Helimerization of Dinaphtho[2,1-b:1',2'-d]pyran-4-one; Liebigs Ann. Chem. 1994, 91-97.

    142)

    F. Bökman, H. Bertagnolli, O. Schupp, G. Bringmann; An EXAFS spectroscopic study of the structure of lactone-brigded biaryls coordinated to CpZrCl3 in toluene solution; J. Organomet. Chem. 1994, 474, 117-122.

    141)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, O. Schupp; Crystal structure of 2-bromomethyl-1-(2'-methoxy-3,5-dimethyl)-naphthalene; Z. Kristallogr. 1994, 209, 801-802.

    140)*

    M.R. Boyd, J.H. Cardellina II, K.P. Manfredi, J.W. Blunt, L.K. Pannell, J.B. McMahon, R.J. Gulakowski, G.M. Cragg, G. Bringmann, D. Thomas, J. Jato (U.S. Dept. of Health and Human Services); Michellamine Antiviral Agents, Compositions, and Treatment Methods; U.S. Patent No. 5,455,251; issued 3.10.1995. - Michellamines Useful as Antiviral Agents; PCT International Publication No. WO 94/24108 (27.10.1994). Filed: 19.04.1993 (Appl.-No. 49,824).

    139)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, M. Gassen; Crystal structure of Z-2-(6,7-dimethoxytetrahydroisoquino-1-ylidene)-[2-(3,4-dimethoxyphenyl)-ethyl]-acetamide; Z. Kristallogr. 1994, 209, 667-668.

    138)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, B. Schwarz, T. Egner; Crystal structure of 3',5'-dimethylphenyl 3-bromo-4,6,7-trimethoxy-2-naphthoate; Z. Kristallogr. 1994, 209, 526-527.

    137)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Hartung; Crystal structure of dinaphth[2,1-c:1',2'-e]oxepin-3-(5H)-on, a lactone-bridged chiral binaphthalene; Z. Kristallogr. 1994, 209, 738-739.

    136)

    G. Bringmann, S. Gramatzki, C. Müller, P. Proksch; Structure-Activity Relationships of Naphthylisoquinoline Alkaloids: Feeding Experiments with the Herbivorous Insect Spodoptera littoralis; Planta Med. 1993, 59 (Suppl.), 624.

    135)

    G. Bringmann, C. Schneider, F. Pokorny, Hj. Lorenz, H. Fleischmann, A.S. Sankara­narayanan, M.R. Almeida, T.R. Govindachari, L. Aké Assi; The Cultivation of Tropical Lianas of the Genus Ancistrocladus; Planta Med. 1993, 59 (Suppl.), 623-624.

    134)

    G. Bringmann, C. Schneider, L. Aké Assi; Ancistrobarterine A: A New "Mixed" Ancistrocladaceae/Dioncophyllaceae-Type Alkaloid from Ancistrocladus barteri; Planta Med. 1993, 59 (Suppl.), 620-621.

    133)

    G. Bringmann, W. Koch, D. Koppler, M. Rübenacker, L. Aké Assi; A New Atropisomeric Dioncophylline A Derivative from Triphyophyllum peltatum; Planta Med. 1993, 59 (Suppl.), 621-622.

    132)

    G. Bringmann, C. Kehr, U. Dauer, K.-P. Gulden, R.D. Haller, S. Bär, M.A. Isahakia, S.A. Robertson, K. Peters; Ancistrocladus robertsoniorum "Produces" Pure Crystalline Droserone when Wounded; Planta Med. 1993, 59 (Suppl.), 622-623.

    131)

    G. Bringmann, D. Koppler, D. Scheutzow; The Elucidation of the Relative Configuration at the Biaryl Axes of Naphthylisoquinoline Alkaloids using "Long Range" NMR Effects; Planta Med. 1993, 59 (Suppl.), 580.

    130)

    G. Bringmann, T. Geuder, F. Pokorny, M. Schäffer, R. Zagst; The Determination of the Absolute Configuration of N-Methylated 1,3-Dimethyltetrahydroisoquinolines, by Oxidative Degradation; Planta Med. 1993, 59 (Suppl.), 619-620.

    129)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, D. Leimkötter, E. Urlaub; Crystal structure of racemic trans-2-(4-methylphenyl)-cyclohexanol; Z. Kristallogr. 1994, 209, 799-800.

    128)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, L. Göbel; Crystal structure of (S)-1-cyano-2-(1'-phenylethyl)-isoindole; Z. Kristallogr. 1994, 209, 524-525.

    127)

    T.S. Ertel, S. Hückmann, H. Bertagnolli, G. Bringmann, O. Schupp; EXAFS studies of a chiral rhenium lactone complex and its precursors including multiple scattering calculations; Inorg. Chim. Acta 1994, 222, 27-36.

    126)

    K. Birken, C. Helf, U. Küster, K.-P. Gulden, M. Stahl, G. Bringmann; Adaptive Hyperflächen im Rechnerverbund; Benutzerinform. Rechenzentr. Univ. Stuttgart 1994, 4-9.

    125)

    G. François, G. Bringmann, J.D. Phillipson, L. Aké Assi, C. Dochez, M. Rübenacker, C. Schneider, M. Wéry, D.C. Warhurst, G.C. Kirby; Activity of Extracts and Naphthylisoquinoline Alkaloids from Triphyophyllum peltatum, Ancistrocladus abbreviatus and A. barteri against Plasmodium falciparum in vitro; Phytochemistry 1994, 35, 1461-1464.

    124)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Hartung; Crystal structure of rac 1-(2-hydroxy-4,6-di-tert-butylphenyl)-2-naphthalenemethanol; Z. Kristallogr. 1994, 209, 740-741.

    123)

    G. Bringmann, T. Mader, K. Peters, H.G. von Schnering; Unexpected Hydantoin Formation in the Attempted Amidation with 2-Aminobenzophenone of Glyoxylic Acid using Dicyclohexylcarbodiimide; J. Chem. Soc., Chem. Commun. 1993, 12, 1001-1002.

    122)

    G. Bringmann, R. Zagst, M. Schäffer, Y.F. Hallock, J.H. Cardellina II, M.R. Boyd;  The Absolute Configuration of Michellamine B, a "Dimeric", Anti-HIV-Active Naphthylisoquino­line Alkaloid; Angew. Chem. 1993, 105, 1242-1243; Angew. Chem. Int. Ed. Engl. 1993, 32, 1190-1191.

    121)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Mader; Crystal structure of N-carbobenzoxy-glycine; Z. Kristallogr. 1994, 209, 456-457.

    120)

    G. Bringmann, D. Feineis; Induzierte Säugeralkaloide - Thiazolidin-Bildung als Schlüssel­schritt zu neuen Therapiekonzepten? Nachr. Chem. Techn. Lab. 1993, 41, 419-427.

    119)

    G. Bringmann, R. Weirich, H. Reuscher, J.R. Jansen, L. Kinzinger, T. Ortmann; The Synthesis of All Possible Isomeric 6,8-Dioxygenated 1,3-Dimethyl-1,2,3,4-tetrahydroisoquinoline Methyl Ethers - Useful Chiral Building Blocks for Naphthylisoquinoline Alkaloids; Liebigs Ann. Chem. 1993, 877-888.

    118)

    G. Bringmann, L. Göbel, O. Schupp; Ein konzeptionell neuer Zugang zu axialchiralen Biarylen - Die atropselektive Öffnung stereochemisch labiler cyclischer Biarylvorstufen; GIT Fachz. Lab. 1993, 37, 189-200.

    117)

    G. Bringmann, L. Kinzinger, T. Ortmann, N.J. de Souza; Isoancistrocladine from Ancistrocladus heyneanus: The First Naturally Occurring N-Unsubstituted cis-Configurated Naphthyltetrahydroisoquinoline Alkaloid; Phytochemistry 1994, 35, 259-261.

    116)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, K. Rölfing; Crystal structure of meso-1,2-bis(1'-bromo-2'-naphthyl)-1,2-dihydroxyethane; Z. Kristallogr. 1993, 207, 129-132.

    115)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, K. Rölfing; Crystal structure of (E)-1-(1-bromo-2-naphthyl)-2-(3,5-dimethoxyphenyl)ethene; Z. Kristallogr. 1993, 207, 125-128.

    114)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, J.R. Jansen; Crystal structure of (1S,3S)-2-benzyl-6-hydroxy-8-methoxy-1,3-dimethyl-1,2,3,4-tetrahydroisoquinoline hydrobromide; Z. Kristallogr. 1993, 207, 133-136.

    113)

    G. Bringmann, F. Pokorny, M. Stäblein, M. Schäffer, L. Aké Assi; Ancistrobrevine C from Ancistrocladus abbreviatus: the first mixed "Ancistrocladaceae/Dioncophyllaceae-type" naphthylisoquinoline alkaloid; Phytochemistry 1993, 33, 1511-1515; 34, 1663.

    112)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, D. Leimkötter; Crystal structure of 2S,4S-2,4-carboxymethyl-5,5-dimethyl-1,3-thiazolidine; Z. Kristallogr. 1993, 208, 223-226.

    111)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, C. Hesselmann, D. Leimkötter; Crystal structure of 2S,4S-2,4-carboxymethyl-1,3-dimethylthiazolidine hydrochloride; Z. Kristallogr. 1993, 206, 267-270.

    110)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Geuder; Crystal structure of a C2-symmetric Schiff base from 1,4-diacetyl-2,3,5,6-tetramethoxybenzene and (S)-1-phenyl­ethylamine; Z. Kristallogr. 1993, 207, 121-124.

    109)

    H. Friedrich, G. Bringmann, W. Kolasiewicz, K.-H. Sontag, W.-D. Rausch; "TaClo", ein Chloral-abgeleitetes Tetrahydro-ß-carbolin mit potentiell MP-auslösender Wirkung: Spuren­nachweis in biologischer Matrix mit Hilfe von GC/MSD und GC/ECD nach selektiver Pro­benaufarbeitung; in Fortschritte der Analytischen Chemie in Methode und Anwendung, (Ed.: Fachgruppe Analytische Chemie), GDCh-Druck, 1993, pp. 310-312.

    108)

    G. Bringmann, K.-P. Gulden, H. Busse, J. Fleischhauer, B. Kramer, E. Zobel; Circular Dichroism of Naphthyltetrahydroisoquinoline Alkaloids: Calculation of CD Spectra by Semiempirical Methods; Tetrahedron 1993, 49, 3305-3312.

    107)

    C. Grimm, P. Proksch, S. Gramatzki, C. Schneider, G. Bringmann; Deleterious Effects of Naphthylisoquinoline Alkaloids on Survival and Growth of Spodoptera littoralis; Planta Med. 1992, 58 (Suppl. 1), 630.

    106)

    G. Bringmann, S. Gramatzki, R. God, P. Proksch; Enzymatic Biotransformation of Naphthylisoquinoline Alkaloids: First Hints at the Metabolism of Dioncophylline A; Planta Med. 1992, 58 (Suppl. 1), 577-578.

    105)

    G. Bringmann, K.-P. Gulden, H. Busse, J. Fleischhauer, B. Kramer, E. Zobel; The Calculation of CD Spectra for the Elucidation of the Absolute Configuration of Chiral Biaryls; Planta Med. 1992, 58 (Suppl. 1), 705.

    104)

    G. Bringmann, L. Kinzinger, H. Busse, C. Zhao; Isolation, Structure Elucidation, and Total Synthesis of Ancistrocline, an Alkaloid of Ancistrocladus tectorius; Planta Med. 1992, 58 (Suppl. 1), 704.

    103)

    G. Bringmann, R. Weirich, D. Lisch, L. Aké Assi; Ancistrobrevine D: An Unusual Alkaloid from Ancistrocladus abbreviatus; Planta Med. 1992, 58 (Suppl. 1), 703-704.

    102)

    G. Bringmann, R. Zagst, D. Lisch, L. Aké Assi; Dioncoline A and its Atropisomer: "Inverse Hybrid Type" Ancistrocladaceae/Dioncophyllaceae Alkaloids from Ancistrocladus abbreviatus; Planta Med. 1992, 58 (Suppl. 1), 702-703.

    101)

    G. Bringmann, T. Ortmann, M. Rübenacker, L. Aké Assi; Dioncophyllacine B: A New 4-Methoxylated Naphthylisoquinoline Alkaloid from the Leaves of Triphyophyllum peltatum; Planta Med. 1992, 58 (Suppl. 1), 701-702.

    100)

    G. Bringmann, T. Hartung; Atropo-Enantioselective Biaryl Synthesis by Stereocontrolled Cleavage of Configuratively Labile Lactone-Bridged Precursors using Chiral H-Nucleophiles; Tetrahedron 1993, 49, 7891-7902.

    99)

    J. Sundermeyer, K. Weber, H. Werner, N. Mahr, G. Bringmann, O. Schupp; Unexpected ring-expansion of "axially prostereogenic" biaryl lactones by methylenephosphoranyl-substituted imido complexes of molybdenum and tungsten; J. Organomet. Chem. 1993, 444, C37-C40.

    98)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, L. Göbel; Crystal structure of an unexpected adduct of triphenylphosphine oxide to 1-(2'-hydroxy-3',6'-diethylphenyl)-2-bromomethyl)naphthalene; Z. Kristallogr. 1993, 203, 265-268.

    97)

    G. Bringmann, T. Hartung, L. Göbel, O. Schupp, K. Peters, H.G. von Schnering; Synthesis and Structure of Benzonaphthopyrans; Helically Distorted, Bridged Biaryls with Different Steric Hindrance at the Axis; Liebigs Ann. Chem. 1992, 769-775.

    96)

    J. Fleischhauer, A. Koslowski, B. Kramer, E. Zobel, G. Bringmann, K.-P. Gulden, T. Ortmann, B. Peter; Messung und Berechnung der CD-Spektren der Biaryl-Alkaloide Ancistrocladein und Dioncophyllein A; Z. Naturforsch. 1993, 48b, 140-148.

    95)

    T. Grimm, A. Ellebracht, W. Kiefer, G. Bringmann, H. Busse; Vibrational studies in a benzonaphthopyrone: Raman and infrared spectra, normal coordinate analysis and semiempirical calculations; Vibrational Spectrosc. 1993, 5, 181-193.

    94)

    G. Bringmann, S. Güssregen, H. Busse; "ValleyScan": A new two-bond drive technique for the calculation of potential energy surfaces with less computational effort; J. Comput.-Aided Mol. Design 1992, 6, 505-512.

    93)

    G. Bringmann, S. Gramatzki, C. Grimm, P. Proksch; Feeding Deterrency and Growth Retarding Activity of the Naphthylisoquinoline Alkaloid Dioncophylline A against Spodoptera littoralis; Phytochemistry 1992, 31, 3821-3825.

    92)

    G. Bringmann, O. Schupp, K. Peters, L. Walz, H.G. von Schnering; Chiral rhenium complexes [(h5-C5H5)Re(NO)(PPh3)(R,R-lac­tone)]+BF4- of lactone-bridged biaryls as ligands: synthesis, structure, and stereochemical properties; J. Organomet. Chem. 1992, 438, 117-130.

    91)

    G. Bringmann, M. Rübenacker, R. Weirich, L. Aké Assi; Dioncophylline C from the Roots of Triphyophyllum peltatum, the First 5,1'-Coupled Dioncophyllaceae Alkaloid; Phytochemistry 1992, 31, 4019-4024.

    90)

    G. Bringmann, T. Ortmann, R. Zagst, B. Schöner, L. Aké Assi, C. Burschka; (±)-Dionco­phyllacine A, a Naphthylisoquinoline Alkaloid with a 4-Methoxy Substituent from the Leaves of Triphyophyllum peltatum; Phytochemistry 1992, 31, 4015-4018.

    89)

    G. Bringmann, R. Zagst, H. Reuscher, L. Aké Assi; Ancistrobrevine B, the First Naphthyl­isoquinoline Alkaloid with a 5,8'-Coupling Site, and Related Compounds from Ancistro­cladus abbreviatus; Phytochemistry 1992, 31, 4011-4014.

    88)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Hartung; Crystal structure of 1,3-di-tert-butyl-6H-benzo[b]naphtho[1,2-d]pyran-6-one - a severely distorted helicene-like bridged biaryl; Z. Kristallogr. 1992, 202, 275-278.

    87)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Hartung, O. Schupp; Crystal structure of 6H-benzo[1,2-d]pyran-6-one . 0.5 phenol - a useful, "axially prostereogenic" lactone-bridged biaryl; Z. Kristallogr. 1992, 202, 271-274.

    86)

    G. Bringmann, L. Kinzinger; (+)-Ancistrocline, a Naphthylisoquinoline Alkaloid from Ancistrocladus tectorius; Phytochemistry 1992, 31, 3297-3299.

    85)

    G. Bringmann, T. Hartung; First Atropo-Enantioselective Ring Opening of Achiral Biaryls Containing Lactone Bridges with Chiral Hydride-Transfer Reagents Derived from Borane; Angew. Chem. 1992, 104, 782-783; Angew. Chem. Int. Ed. Engl. 1992, 31, 761-762.

    84)

    G. Bringmann, D. Feineis, C. Hesselmann, S. Schneider, M. Koob, D. Henschler; A "Chemical" Concept for the Therapy of Glyoxylate-Induced Oxalurias; Life Sci. 1992, 50, 1597-1605.

    83)

    G. Bringmann; A first biosynthetic proposal for the in vivo formation of naturally occurring diazepam-like 1,4-benzodiazepines; J. Neural Transm. 1992, 88, 77-82.

    82)

    G. Bringmann, T. Hartung; The Atropo-Enantioselective Ring Opening of Achiral Lactone-Bridged Biaryls Using Chirally Modified Aluminum Hydrides; Synthesis 1992, 433-435.

    81)

    G. Bringmann, T. Hartung, L. Göbel, O. Schupp, C.L.J. Ewers, B. Schöner, R. Zagst, K. Peters, H.G. von Schnering, C. Burschka; Synthesis and Structure of Benzonaphthopyranones, Useful Bridged Model Precursors for Stereoselective Biaryl Syntheses; Liebigs Ann. Chem. 1992, 225-232.

    80)

    K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Geuder; Crystal structure of a Schiff base from 2,6-dimethoxyacetophenone and (S)-1-phenylethylamine; Z. Kristallogr. 1992, 201, 157-160.

    79)

    G. Bringmann, C.L.J. Ewers, L. Göbel, T. Hartung, B. Schöner, O. Schupp, R. Walter; Metal-Assisted Atropisomer-Selective Ring Opening of Axially Prostereogenic Biaryl-Lactones; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, A.G. Griesbeck, W. Adam, G. Bringmann, W. Kiefer), Vieweg, Braunschweig, 1992, pp. 183-186.

    78)

    G. Bringmann, H. Busse, S. Güssregen, B. Schöner, R. Zagst, C. Burschka; Structure and Dynamics of Free and Metallated Benzonaphthopyranones and -Pyrans; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, A.G. Griesbeck, W. Adam, G. Bringmann, W. Kiefer), Vieweg, Braunschweig, 1992, pp. 179-182.

    77)

    G. Bringmann, C.L.J. Ewers, L. Göbel, T. Hartung, L. Kinzinger, M. Schäffer, B. Schöner, O. Schupp; Synthesis of "Axially Prostereogenic" Bridged Biaryls and their Metal Complexes; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, A.G. Griesbeck, W. Adam, G. Bringmann, W. Kiefer), Vieweg, Braunschweig, 1992, pp. 175-178.

    76)

    D. Feineis, G. Bringmann, C. Hesselmann; Nachweis Carboxy-substituierter 1,3-Thiazolidine mittels HPLC für ein "chemisches" Konzept zur Behandlung Glyoxylsäure-induzierter Oxalurien; in 11. Königsteiner Chromatographie-Tage 1991, GIT Verlag, Darmstadt, 1991, pp. 204-213.

    75)

    G. Bringmann, D. Feineis, C. Hesselmann; Determination of 1,3-Thiazolidine-Carboxylic Acids in Urine by Reversed-Phase HPLC after Fluorescence Labelling with Dansyl Chloride; Anal. Lett. 1992, 25, 497-512.

    74)

    G. Bringmann, C. Hesselmann, D. Feineis; Analysis of glyoxylate-derived 1,3-thiazolidines by ion-pair-assisted reversed-phase chromatography; J. Chromatogr. 1992, 595, 351-354.

    73)

    A.G. Griesbeck, S. Stadtmüller, H. Busse, G. Bringmann, J. Buddrus; Photoreaktionen zwischen 2-Cyclopenten-1-on und Enolethern; Chem. Ber. 1992, 125, 933-940.

    72)

    G. Bringmann, H. Friedrich, D. Feineis; Trichloroharmanes as potential endogenously formed inducers of Morbus Parkinson: synthesis, analytics, and first in vivo investigations; J. Neural Transm. 1992, 38 [Suppl.], 15-26.

    71)

    G. Bringmann, R. Walter, C.L.J. Ewers; Diastereoselective Ring Opening of Achiral Bridged Bi­aryls Using Chiral O- and N-Nucleophiles: First Atropo-Enantioselective Synthesis of (-)-4,4'-Bis(orcinol); Synlett 1991, 581-583.

    70)*

    G. Bringmann, M. Rübenacker, E. Ammermann, G. Lorenz, L. Aké Assi (BASF AG); Anwendung von Dioncophyllinen als Fungizide; German Patent D.O.S. DE 41 17 080 A 1, disclosure 26.11.92. - Dioncophyllines A and B as fungicides; European Patent EP 0515 856 A1, disclosure 02.12.1992.

    69)

    G. Bringmann, F. Pokorny, M. Stäblein, T.R. Govindachari, M.R. Almeida, S.M. Ketkar; On the Biosynthesis of Acetogenic Tetrahydroisoquinoline Alkaloids: First In Vivo Feeding Experiments; Planta Med. (Suppl. 2) 1991, 57, 98.

    68)

    G. Bringmann, C. Schneider, L. Aké Assi; Direct and Modified Bicyclic Moieties of Naphthylisoquinoline Alkaloids from Ancistrocladus barteri: First Biosynthetic Indicators?; Planta Med. (Suppl. 2) 1991, 57, 10.

    67)

    G. Bringmann, F. Pokorny, M. Stäblein, L. Aké Assi; Ancistrobrevine C: A "Mixed" Ancistrocladaceae/Dioncophyllaceae-Type Naphthylisoquinoline Alkaloid from Ancistro­cladus abbreviatus; Planta Med. (Suppl. 2) 1991, 57, 97-98.

    66)

    G. Bringmann, R. Zagst, L. Aké Assi; Ancistrobrevine B: A Naphthylisoquinoline Alkaloid with a Novel Coupling Type from Ancistrocladus abbreviatus; Planta Med. (Suppl. 2) 1991, 57, 96-97.

    65)

    G. Bringmann, T. Ortmann, M. Rübenacker, L. Aké Assi; An Unusual 4-Methoxylated Naphthylisoquinoline Alkaloid from the Leaves of Triphyophyllum peltatum; Planta Med. (Suppl. 2) 1991, 57, 96.

    64)

    G. Bringmann, J.R. Jansen; Stereocontrolled Ring Opening of Axially Prostereogenic Biaryl Lactones with Hydrogen Nucleophiles: Directed Synthesis of a Dioncophylline A Precursor and (Option­ally) its Atropodiastereomer; Synthesis 1991, 825-827.

    63)

    G. Bringmann, T. Geuder; The Directed Cleavage of Substituted 1-Phenylethylamines: A Novel Route to Enantiomerically Pure b-Amino Acid Esters and b-Lactams; Synthesis 1991, 829-831.

    62)

    G. Bringmann, M. Rübenacker, T. Geuder, L. Aké Assi; Dioncophylline B, a Naphthyl­isoquinoline Alkaloid with a New Coupling Type from Triphyophyllum peltatum; Phytochemistry 1991, 30, 3845-3847.

    61)

    G. Bringmann, F. Pokorny, H.D. Zinsmeister; Ancistrocladus, eine botanisch und chemisch bemerkenswerte Gattung; Der Palmengarten  1991, 55, 13-18.

    60)

    G. Bringmann, A. Hille, M. Stäblein, K. Peters, H.G. von Schnering; Potential Tryptophan-Derived Alkaloids in Chloral-Treated Patients: Synthesis and Stereostructure; Liebigs Ann. Chem. 1991, 1189-1194.

    59)

    G. Bringmann, M. Rübenacker, P. Vogt, H. Busse, L. Aké Assi, K. Peters, H.G. von Schnering; Dioncopeltine A and Dioncolactone A: Alkaloids from Triphyophyllum peltatum; Phytochemistry 1991, 30, 1691-1696.

    58)

    T. Ertel, S. Hückmann, H. Bertagnolli, G. Bringmann, C.L.J. Ewers, G. Erker, I. Hart, C. Sarter; Zirconium complexes of "Axially prostereogenic" benzocoumarin-type lactones: EXAFS determination of the metal environment; in X-Ray Absorption Fine Structure (Ed.: S.S. Hasnain), Ellis Horwood Publishers, New York, 1991, pp. 562-565.

    57)

    G. Bringmann, R. Zagst, B. Schöner, H. Busse, M. Hemmerling, C. Burschka; Structure of the Naphthyl Isoquinoline Alkaloid Dioncophylline A; Acta Cryst. 1991, C 47, 1703-1705.

    56)

    G. Bringmann, T. Geuder, M. Rübenacker, R. Zagst; A Facile Degradation Procedure for Determination of Absolute Configuration in 1,3-Dimethyltetra- and Dihydroisoquinolines; Phytochemistry 1991, 30, 2067-2070.

    55)

    G. Bringmann, J.R. Jansen, H. Busse; An Atropoisomer-Differentiating Reaction for the Chemical Analysis of Axial Chirality and Its Computational Investigation: Proof of the Stereostructure of Dioncophylline A; Liebigs Ann. Chem. 1991, 803-809.

    54)

    G. Bringmann, D. Feineis, H. Friedrich, A. Hille; Endogenous Alkaloids in Man - Synthesis, Analytics, in vivo Identification, and Medicinal Importance; Planta Med. (Suppl. 1) 1991, 57, 73-84.

    53)

    G. Bringmann, D. Lisch, H. Reuscher, L. Aké Assi, K. Günther; Atrop-Diastereomer Separation by Racemate Resolution Techniques: N-Methyl-Dioncophylline A and its 7-Epimer from Ancistrocladus abbreviatus; Phytochemistry 1991, 30, 1307-1310.

    52)

    G. Bringmann, C.L.J. Ewers, R. Walter; Functional Group Interconversion: Use of Carbonyl Derivatives for Heterocyclic Synthesis; in Comprehensive Organic Synthesis, vol. 6, (Ed.: B.M. Trost), Heteroatom Manipulation (Vol.-Ed.: E. Winterfeldt), Pergamon Press, Oxford, 1991, pp. 733-762.

    1990-1986

    51)*

    G. Bringmann, J.R. Jansen, J.-P. Geisler (BASF AG); Verfahren zur Herstellung von optisch aktiven a-Aminoacetalen; German patent D.O.S. DE 38 43 390 A 1, disclosure 05.07.90. - Preparation of Optically Active a-Amino Acetals from a-Oxo Acetals via Schiff Bases; European Patent EP 0 374 647 B 1, disclosure 15.06.94.

    50)

    G. Bringmann, R. Walter, R. Weirich; The Directed Synthesis of Biaryl Compounds: Modern Concepts and Strategies; Angew. Chem. 1990, 102, 1006-1019; Angew. Chem. Int. Ed. Engl. 1990, 29, 977-991.

    49)

    G. Bringmann, F. Pokorny, H. Reuscher, D. Lisch, L. Aké Assi; Novel Ancistrocladaceae and Dioncophyllaceae Type Naphthylisoquinoline Alkaloids from Ancistrocladus abbreviatus: a Phylogenetic Link Between the Two Families?; Planta Med. 1990, 56, 496-497.

    48)

    G. Bringmann, M. Rübenacker, J.R. Jansen, T. Geuder, L. Aké Assi; Isolation, Structure Elucidation, and Stereoselective Total Synthesis of Novel Alkaloids from Triphyophyllum peltatum; Planta Med. 1990, 56, 495-496.

    47)

    G. Bringmann, J.-P. Geisler, T. Geuder, G. Künkel, L. Kinzinger; The Enantioselective Synthesis of Optically Active, Benzene Nucleus-Substituted 1-Phenylethylamines from the Corresponding Acetophenones; Liebigs Ann. Chem. 1990, 795-805.

    46)

    G. Bringmann, J.-P. Geisler; A Facile Method for the Asymmetric Synthesis of Enantio­merically Pure 1-(2-Fluorophenyl)-ethylamine; J. Fluor. Chem. 1990, 49, 67-73.

    45)

    G. Bringmann, G. Künkel, T. Geuder; Enantiomerically Pure N-Boc Protected ß-Keto-g-Amino Acid Esters from Simple Keto Precursors: A Novel, Stereocontrolled Approach to Statine Derivatives with Any Desired Configuration; Synlett 1990, 253-256.

    44)

    G. Bringmann, A. Hille; 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline - A Potential Chloral-Derived Indol Alkaloid in Man; Arch. Pharm. 1990, 323, 567-569.

    43)

    G. Bringmann, J.R. Jansen, H. Reuscher, M. Rübenacker, K. Peters, H.G. von Schnering; First Total Synthesis of (-)-Dioncophylline A ("Triphyophylline") and of Selected Stereoisomers: Complete (Revised) Stereostructure; Tetrahedron  Lett. 1990, 31, 643-646.

    42)

    G. Bringmann, M. Rübenacker, J.R. Jansen, D. Scheutzow, L. Aké Assi; On the Structure of the Dioncophyllaceae Alkaloids Dioncophylline A ("Triphyophylline") and "O-Methyl-Triphyophylline"; Tetrahedron Lett. 1990, 31, 639-642.

    41)

    B. Höhl, M. Arnemann, L. Schwenen, D. Stöckl, G. Bringmann, J.R. Jansen, W. Barz; Degradation of the Pterocarpan Phytoalexin (-)-Maackiain by Ascochyta rabiei; Z. Naturforsch. 1989, 44c, 771-776.

    40)

    G. Bringmann, H. Reuscher; Atropdiastereoselective Ring Opening of Bridged, "Axial-Prostereogenic" Biaryls: Directed Synthesis of (+)-Ancistrocladisine; Angew. Chem. 1989, 101, 1725-1726; Angew. Chem. Int. Ed. Engl. 1989, 28, 1672-1673.

    39)

    G. Bringmann, H. Reuscher; Aryl-Coupling via "Axially Prostereogenic" Lactones: First To­tal Synthesis of (+)-Ancistrocladisine and (Optionally) its Atropisomer; Tetrahedron Lett. 1989, 30, 5249-5252.

    38)

    G. Bringmann, J.-P. Geisler; A Simple, Chiral-Pool-Independent Synthesis of Enantio­merically Pure Alanine-Derived a-Amino Aldehyde Acetals; Synthesis 1989, 608-610.

    37)*

    G. Bringmann, J.-P. Geisler, J.R. Jansen (BASF AG); Verfahren zur Herstellung von optisch aktiven 1-Arylethylaminen; German Patent D.O.S. DE 38 19 438 A1, disclosure 19.01.89.

    36)

    G. Bringmann, J.R. Jansen; Chiral Economy with Respect to Rotational Isomerism: Rational Synthesis of Hamatine and (Optionally) Ancistrocladine from Joint Helical Precursors; Heterocycles 1989, 28, 137-142.

    35)

    G. Bringmann, J.-P. Geisler; Enantiomerically Pure Oxygenated 1-Phenylethylamines from Substituted Acetophenones: By Reductive Amination and Regiospecific Benzylic Cleavage; Tetrahedron Lett. 1989, 30, 317-320.

    34)

    G. Bringmann, J.R. Jansen, A. Hille, H. Reuscher; The Stereocontrolled Total Synthesis of Naphthyl Isoquinoline Alkaloids; in 6ème Colloque International, consacré aux Plantes Médicinales et Substances d'Origine Naturelle, Angers, France, 1988, pp. 181-207.

    33)

    H. Kessmann, K. Tiemann, J.R. Jansen, H. Reuscher, G. Bringmann, W. Barz; In Vivo Characterization of NADPH: 2'-Hydroxyisoflavone Oxidoreductase in Elicitor Treated Chick­pea Cell Cultures and Stereochemical Aspects of the Phytoalexins Medicarpin and Maackiain; in Plant Cell Biotechnology, NATO ASI Series H: Cell Biology, vol. 18, (Eds.: M.S.S. Pais, F. Mavituna, J.M. Novais), Springer Verlag, Berlin, 1988, pp. 231-238.

    32)

    G. Bringmann, S. Schneider, K.D. Richter; HPLC-Analytik hochpolarer Pyridoxyl-Alka­loide im Säugerblut; Fresenius Z. Anal. Chem., 1987, 329, 480-484.

    31)

    G. Bringmann, A. Hille, M. Zsiška; First Synthesis of 1-Trichloromethyl-6,7-dihydroxy-tetrahydroisoquinoline - an Imaginable Chloral-Derived Mammalian Alkaloid; Heterocycles 1987, 26, 2587-2590.

    30)

    G. Bringmann, J.R. Jansen, H.-P. Rink; Regioselective and Atropisomeric-Selective Aryl Coupling to Give Naphthyl Isoquinoline Alkaloids: The First Total Synthesis of (-)-Ancistrocladine; Angew. Chem. 1986, 98, 917-919; Angew. Chem. Int. Ed. Engl. 1986, 25, 913-915.

    29)

    G. Bringmann; The Naphthyl Isoquinoline Alkaloids; in The Alkaloids, vol. 29, (Ed.: A. Brossi), Academic Press, New York, 1986, pp. 141-184.

    28)

    G. Bringmann, J.R. Jansen; One Pot Preparation of 1,3-Dimethyltetrahydroisoquinolines from their Biosynthetic Diketo Precursors; Heterocycles 1986, 24, 2407-2410.

    27)

    G. Bringmann, S. Schneider, A. Hille; Endogene Alkaloide im Säugerorganismus; Nachr. Chem. Tech. Lab. 1986, 34, 222-226.

    26)

    G. Bringmann, S. Schneider; Rational Synthesis of Deuterium-Labelled Pyridoxal and Pyridoxyl Alkaloids; Tetrahedron Lett. 1986, 27, 175-178.

    25)

    G. Bringmann, S. Schneider; The First Evidence of Endogenous Pyridoxyl Isoquinoline Alkaloids in Mammalian Organisms; Angew. Chem. 1986, 98, 167; Angew. Chem. Int. Ed. Engl. 1986, 25, 177-178.

    1985-1977

    24)

    G. Bringmann; Biomimetische Synthesen beider Molekülhälften der Ancistro­cladus- und der Triphyophyllum-Alkaloide aus gemeinsamen Vorstufen; Liebigs Ann. Chem. 1985, 2126-2134.

    23)

    G. Bringmann, J.R. Jansen; Einfache Synthesen nützlicher Diketo-Bausteine für biomimetische Isochinolin- und Naphthalin-Synthesen; Liebigs Ann. Chem. 1985, 2116-2125.

    22)

    G. Bringmann; Aufbau und Cyclisierung zentral modifizierter ß-Pentaketone: Synthese monocyclischer Isochinolinalkaloid-Vorstufen; Liebigs Ann. Chem. 1985, 2105-2115.

    21)

    G. Bringmann; Isochinoline aus Polyketid-Vorstufen: Ausgefallene Biosynthesewege als Vorbild neuartiger Alkaloid-Synthesen; in Festschrift 35 Jahre Fonds der Chemischen Industrie, Frankfurt, 1985, pp. 151-159.

    20)

    G. Bringmann, S. Schneider; Aufbau und Cyclisierung terminal geschützter ß-Pentaketone: Erste Synthese des Aloenin-Aglycons; Liebigs Ann. Chem. 1985, 765-774.

    19)

    G. Bringmann, D. Heubrock; Sind Alkoholiker verkappte Morphinisten?; Psychologie Heute 1985, 12, 47-51.

    18)

    G. Bringmann, J.R. Jansen; A First and General Route to Naphthylisoquinoline Alkaloids: The Total Synthesis of O-Methyl-tetradehydro-triphyophylline; Tetrahedron Lett. 1984, 25, 2537-2540.

    17)

    G. Bringmann, S. Schneider; Improved Methods for Dehydration and Hydroxy/Halogen Exchange using Novel Combinations of Triphenylphosphine and Halogenated Ethanes; Synthesis 1983, 139-141.

    16)

    G. Bringmann, S. Schneider; Biomimetic First Synthesis of the Aloenin Aglycon; Heterocycles 1982, 19, 1449-1452.

    15)

    G. Bringmann; A Short Biomimetic Synthesis of the Isoquinoline and the Naphthalene Moieties of Ancistrocladus Alkaloids from Common ß-Polycarbonyl Precursors; Tetrahedron Lett. 1982, 23, 2009-2012.

    14)

    G. Bringmann, B. Franck; Extrem selektive Porphyrin-Bildung bei der Cyclisierung verschiedener Oligopyrrole; Liebigs Ann. Chem. 1982, 1272-1279.

    13)

    G. Bringmann, B. Franck; Synthese linearer Di-, Tri-, Tetra- und Pentapyrrole mit natürlichen Seitenketten und günstigen Eigenschaften; Liebigs Ann. Chem. 1982, 1261-1271.

    12)

    G. Bringmann; Isoquinolines and Naphthalenes from ß-Polyketones: Model Reactions for an Extraordinary Alkaloid Biosynthesis; Angew. Chem. 1982, 94, 205; Angew. Chem. Int. Ed. Engl. 1982, 21, 200.

    11)

    D.H.R. Barton, G. Bringmann, W.B. Motherwell; The Selective Modification of Neamine by Radical-induced Deamination; J. Chem. Soc., Perkin Trans. 1, 1980, 2665-2669.

    10)

    D.H.R. Barton, G. Bringmann, G. Lamotte, W.B. Motherwell, R.S. Hay Motherwell, E.A.E. Porter; A Useful Radical-deamination Reaction; J. Chem. Soc., Perkin Trans. 1, 1980, 2657-2664.

    9)

    B. Franck, W. Bock, G. Bringmann, G. Fels, F. Grubenbecher, M. Marsmann, R. Pietschmann, K. Schäpers, U. Spiegel, R. Steinkamp, G. Ufer, C. Wegner; Chemistry of Porphyrin Biosynthesis: Results and Applications; Int. J. Biochem. 1980, 11, 671-679.

    8)

    B. Franck, G. Bringmann, G. Flohr; Sequence Analysis of Ergochrome-Biosynthesis by Competitive Incorporation; Angew. Chem. 1980, 92, 483-484; Angew. Chem. Int. Ed. Engl. 1980, 19, 460-461.

    7)

    G. Bringmann; Endogene Opiate im Menschen, Spontane Bildung von Alkaloid-Drogen; Umschau Wiss. Tech. 1980, 80, 247-248.

    6)

    B. Franck, G. Bringmann, C. Wegner, U. Spiegel; Einfache biomimetische Porphyrin-Synthesen; Liebigs Ann. Chem. 1980, 263-274.

    5)

    B. Franck, C. Wegner, G. Bringmann, G. Fels; Synthese von geschütztem Nor- und Homoporphobilinogen; Liebigs Ann. Chem. 1980, 253-262.

    4)

    D.H.R. Barton, G. Bringmann, W.B. Motherwell; Radical-Induced Reductive Deamination of Amino Acid Esters; Synthesis 1980, 68-70.

    3)

    D.H.R. Barton, G. Bringmann, G. Lamotte, R.S. Hay Motherwell, W.B. Motherwell; Radical Deamination Reactions of Relevance to Aminoglycoside Chemistry; Tetrahedron Lett. 1979, 20, 2291-2294.

    2)

    G. Bringmann; Chemische Mechanismen der Alkohol-Wirkung; Naturwissenschaften 1979, 66, 22-27.

    1)

    B. Franck, G. Fels, G. Ufer, R. Steinkamp, C. Wegner, G. Bringmann; Heterocyclic Chemistry Related to Porphyrins; Heterocycles  1977, 6, 1541-1546.

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