Publications
2024
800) D. Feineis, G. Bringmann; Structural variety and pharmacological potential of naphthylisoquinoline alkaloids;
in The Alkaloids, Vol. 91 (Ed.: H.-J. Knoelker), Academic Press, New York, 2024, pp. 1-410 (https://doi.org/10.1016/bs.alkal.2024.03.001).
799) H.T. Bakhsh, D.H. Abu-Baih, R.H. Abu-Baih, E.A. Saber, F.H. Altemani, N.A. Algehainy, M.A. Alanazi, F. A. Mokhtar, G. Bringmann, U.R. Abdelmohsen, F.M. Abd El-Mordy; Unveiling the neurotprotective potential of Lobophytum sp. for Parkinson's disease through multifaceted mechanisms, supported by metabolomic analysis and network pharmacology. Sci. Rep. 2024, 14, 21810 (https://doi.org/10.1038/s41598-024-66781-9).
798) D. Soost, G. Bringmann, H. Ihmels; The N-biphenyldihydroisoquinolinium scaffold as a novel motif for selective fluorimetric detection of quadruplex DNA. Org. Chem. Front. 2024, Advance Article (https://doi.org/10.1039/d4qo01193g).
797) R. Damiescu, M. Dawood, M. Elbadawi, S.M. Klauck, G. Bringmann, T. Efferth; Identification of cytisine derivatives as agonists of the human delta opioid receptor by supercomputer-based virtual drug screening and transcriptomics. ACS Chem. Biol. 2024, online ahead of print (https://doi.org/10.1021/acschembio.4c00231).
796) E.M. Zahran, M.F. Abdelwahab, R.H. Mohyeldin, O.Y. Tammam, N.M.R. Abdel-Maqsoud, F.H. Altemani, N.A. Algehainy, M.A. Alanazi, M.M. Jalal, M.A. Elrehany, G. Bringmann, U.R. Abdelmohsen; Combination of Callyspongia sp. and stem cells for wound repair and skin regeneration: in vivo and in silico evidences. Chem. Biodiversity 2024, e202400682, online ahead of print (https://doi.org/10.1002/cbdv.202400682).
795) N. Shahhamzehei, S. Abdelfatah, H.S. Schwarzer Sperber, K. Sutter, R. Yücer, G. Bringmann, R. Schwarzer, T. Efferth; Identification of nitrile-containing isoquinoline-related natural product derivatives as coronavirus entry inhibitors in silico and in vitro. Biomed. Pharmacother. 2024, 180, 117517 (https://doi.org/10.1016/j.biopha.2024.117517).
794) R. Damiescu, M. Elbadawi, M. Dawood, S.M. Klauck, G. Bringmann, T. Efferth; Aniquinazoline B, a fungal natural product, activates the µ-opioid receptor;
ChemMedChem 2024 , e202400213, with Cover Picture (https://doi.org/10.1002/cmdc.202400213).
793) F.H. Altemani, A.H. Elmaidomy, D.H. Abu-Baih, A.M. Abdel Zaher, F.A. Mokhtar, N.A. Algehainy, H.T. Bakhsh, G. Bringmann, U.R. Abdelmohsen, O.H. Abdelhafez; Tamarix aphylla derived metabolites ameliorate indomethacin-induced gastric ulcers in rats by modulating the MAPK signaling pathway, alleviating oxidative stress and inflammation: In vivo study supported by pharmacological network analysis. PLoS ONE 2024, 19, e0302015 (https://doi.org/10.1371/journal.pone.0302015).
792) M.H. ElNaggar, U.R. Abdelmohsen, F.M. Bar, A.A. Kamer, G. Bringmann, E. Elekhnawy; Investigation of bioactive components responsible for the antibacterial and anti-biofilm activities of Caroxylon volkensii by LC-QTOF-MS/MS analysis and molecular docking. RSC Adv. 2024, 14, 11388-11399 (https://doi.org/10.1039/d4ra01646g).
791) S.A. Khalid, S.A. Algaffar, N. Tajuddeen, B.K. Lombe, G. Bringmann; Naphthylisoquinoline alkaloids: novel agents against the causative pathogens of eumycetoma and actinomycetoma - en route to broad-spectrum antimycetomal drugs. Antimicrob. Agents Chemother. 2024, 68, e01612-23 (https://doi.org/10.1128/aac.01612-23).
790) E.M. Zahran, R.H. Mohyeldin, F.M. Abd El-Mordy, S.A. Maher, N.M.R. Abdel-Maqsoud, F.H. Altemani, N.A. Algehainy, M.A. Alanazi, M.M. Jalal, M.A. Elrehany, G. Bringmann, U.R. Abdelmohsen; Wound healing potential of Cystoseira / mesenchymal stem cells in immunosuppressed rats supported by overwhelming immuno-inflammatory crosstalk. PLoS ONE 2024, 19, e0300543 (https://doi.org/10.1371/journal.pone.0300543).
789) A.H. Elmaidomy, U.R. Abdelmohsen, A.M. Sayed, F.H. Altemani, N.A. Algehainy, D. Soost, T. Paulutat, G. Bringmann, E.M. Mohamed; Antiplasmodial potential of phytochemicals from Citrus aurantifolia peels: a comprehensive in vitro and in silico study. BMC Chemistry 2024, 18, 60 (https://doi.org/10.1186/s13065-024-01162-x).
788) R. Damiescu, R. Yücer, S.M. Klauck, G. Bringmann, T. Efferth, M. Dawood; Jozimine A2, a dimeric naphthylisoquinoline (NIQ) alkaloid, shows in vitro cytotoxic effects against leukemia cells through NF-kB inhibition; Int. J. Mol. Sci. 2024, 25, 3087 (https://www.mdpi.com/1422-0067/25/6/3087).
787) J. Maneenet, N. Tajuddeen, H.H. Nguyen, R. Fujii, B.K. Lombe, D. Feineis, S. Awale, G. Bringmann; Droserone and dioncoquinone B, and related naphthoquinones as potent antiausterity agents against human PANC-1 pancreatic cancer cells; Results Chem. 2024, 7, 101352 (https://doi.org/10.1016/j.rechem.2024.101352).
786) D.H. Abu-Baih, A. Abdel-Rahman Gomaa, N.M. Abdel-Wahab, E.R. Abdelaleem, A.M. Abdel Zaher, N.F. Hassan, G. Bringmann, U.R. Abdelmohsen, F.H. Altemani, N.A. Algehainy, F.A. Mokhtar, M.F. Abdelwahab; Apium extract alleviates indomethacin-induced gastric ulcers in rats via modulating the VEGF and IK-kB/NF-kB p65 signaling pathway: insights from in silico and in vivo investigations; BMC Complement. Med. Ther. 2024, 24, 88 (https://doi.org/10.1186/s12906-023-04333-w).
785) H.T. Bakhsh, O.H. Abdelhafez, A.H. Elmaidomy, H.F. Aly, E.A. Younis, M.A. Alzubaidi, N.A. Algehainy, F.H. Altemani, M. Majrashi, F. Alsenani, G. Bringmann, U.R. Abdelmohsen, F.A. Mokhtar; Anti-Alzheimer potential of Solanum lycopersicum seeds: in vitro, in vivo, metabolomic, and computational investigations; BSU J. Basic Appl. Sci. (BJBAS) 2024, 13, 1-20 (https://doi.org/10.1186/s43088-023-00453-x).
784) R. Yücer, S. Fayez, D. Feineis, S.M. Klauck, L. Shan, G. Bringmann, T. Efferth, M. Dawood;
Cytotoxicity of dioncophylline A and related naphthylisoquinolines in leukemia cells, mediated by NF-kB inhibition, angiogenesis suppression, G2/M cell cycle arrest, and autophagy induction; Phytomedicine 2024, 126, 155267 (https://doi.org/10.1016/j.phymed.2023.155267).
783) N. Tajuddeen, S. Muyisa, J. Maneenet, H.H. Nguyen, D. Naidoo-Maharaj, V. Maharaj, S. Awale, G. Bringmann; Justicidin B and related lignans from two South African Monsonia species with potent activity against HeLa cervical cancer cells;
Phytochem. Lett. 2024, 60, 234-238 (https://doi.org/10.1016/j.phytol.2023.09.007).
782) N. Tajuddeen, S. Fayez, P.P. Kushwaha, D. Feineis, L. Aké Assi, S. Kumar, G. Bringmann; Ancistrobrevinium A, the first N-methylated, cationic naphthylisoquinoline alkaloid, from the tropical liana Ancistrocladus abbreviatus (Ancistrocladaceae); Nat. Prod. Res. 2024, 38, 2614-2618 (https://doi.org/10.1080/14786419.2023.2194648).
2023
781)
780)
779)
778)
777)
776)
775)
774)
773)
772)
771)
770)
|
|
---|
2022
769)
768)
767)
766)
765)
764)
763) |
|
---|
2021
2020
756) | E.M. Zahran, A. Albohy, A. Khalil, A.H. Ibrahim, H.A. Ahmed, E.M. El-Hossary, G. Bringmann, U.R. Abdelmohsen; Bioactivity Potential of Marine Natural Products from Scleractinia-Associated Microbes and In Silico Anti-SARS-COV-2 Evaluation; Mar. Drugs 2020 , 18, 645 (doi:10.3390/md18120645). |
---|
755) | P.P. Kushwaha, A.K. Singh, K.S. Prajapati, M. Shuaib, S. Fayez, G. Bringmann, S. Kumar; Induction of apoptosis in breast cancer cells by naphthylisoquinoline alkaloids; Toxicol. Appl. Pharmacol. 2020, 15, 115297 (https://doi.org/10.1016/j.taap.2020.115297). |
---|---|
754) | J.F. Selby, M. Holzapfel, B.K. Lombe, D. Schmidt, A.-M. Krause, F. Würthner, G. Bringmann, C. Lambert; Chiroptical Properties of Indolenine Squaraines with a Stereogenic Center at Close Proximity; J. Org. Chem. 2020, 85, 12227 (https://doi.org/10.1021/acs.joc.0c01422). |
753) | R.F.A. Abdelhameed, E.E. Eltamany, D.M. Hal, A.K. Ibrahim, A.M. AboulMagd, T. Al-Warhi, K.A. Youssif, A.M. Abd El-kader, H.A. Hassanean, S. Fayez, G. Bringmann, S.A. Ahmed, U.R. Abdelmohsen; New Cytotoxic Cerebrosides from the Red Sea Cucumber Holothuria spinifera Supported by In-Silico Studies; Mar. Drugs 2020 , 18, 405 (https://doi.org/10.3390/md18080405). |
---|---|
752) | M. Dawood, M.-E.F. Hegazy, M. Elbadawi, E. Klinger, A. Klinger, G. Bringmann, C. Kuntner, L. Shan, T. Efferth; Vitamin K3 chloro derivative (VKT-2) inhibits HDAC6, activates autophagy and apoptosis, and inhibits aggresome formation in hepatocellular carcinoma cells; Biomed. Pharmacol. 2020, 180, 114176 (https://doi.org/10.1016/j.bcp.2020.114176). |
751) | M. Dawood, E. Fleischer, A. Klinger, G. Bringmann, L. Shan, T. Efferth; Inhibition of cell migration and induction of apoptosis by a novel class II histone deacetylase inhibitor, MCC2344; Pharmacol. Res. 2020, 160, 105076 (https://doi.org/10.1016/j.phrs.2020.105076). |
---|
750) | M. Dawood, M. Elbadawi, M. Böckers, G. Bringmann, T. Efferth; Molecular docking-based virtual drug screening revealing an oxofluorenyl benzamide and a bromonaphthalene sulfonamido hydroxybenzoic acid as HDAC6 inhibitors with cytotoxicity against leukemia cells; Biomed. Pharmacother. 2020, 129, 110454 (https://doi.org/10.1016/j.biopha.2020.110454). |
---|
749) | R.F.A. Abdelhameed, E.S. Habib, M.S. Goda, J.R. Fahim, H.A. Hassanean, E.E. Eltamany, A.K. Ibrahim, A.M. AboulMagd, S. Fayez, A.M. Abd El-kader, T. Al-Warhi, G. Bringmann, S.A. Ahmed, U.R. Abdelmohsen; Thalassosterol, a New Cytotoxic Aromatase Inhibitor Ergosterol Derivative from the Red Sea Seagrass Thalassodendron ciliatum; Mar. Drugs 2020, 18, 354 (https://www.mdpi.com/1660-3397/18/7/354/pdf). |
---|
748) | G. Bringmann, S. Fayez, W. Shamburger, D. Feineis, S. Winiarczyk, R. Janecki, Ł. Adaszek; Naphthylisoquinoline alkaloids and their synthetic analogs as potent novel inhibitors against Babesia canis in vitro ; Vet. Parasitol. 2020, 283, 109177 (https://doi.org/10.1016/j.vetpar.2020.109177). |
---|
747) | P. Moyo, W. Shamburger, M.E. van der Watt, J. Reader, A.C.C. de Sousa. T.J. Egan, V.J. Maharaj, G. Bringmann, L.-M. Birkholtz; Naphthylisoquinoline Alkaloids, Validated as Hit Multistage Antiplasmodial Natural Products; Int. J. Parasitol. Drugs Drug Resist. 2020, 13, 51-58 (https://doi.org/10.1016/j.ijpddr.2020.05.003). |
---|---|
746) | J. Hofmann, S. Fayez, M. Scheiner, M. Hoffmann, S. Oerter, A. Appelt-Menzel, P. Maher, T. Maurice, G. Bringmann, M. Decker; Sterubin: Enantioresolution and Configurational Stability, Enantiomeric Purity in Nature, and Neuroprotective Activity in Vitro and in Vivo; Chem. Eur. J. 2020, 26, 7299-7308 (https://doi.org/10.1002/chem.202001264). |
745) | R.F.A. Abdelhameed, E.S. Habib, N.A. Eltahawy, H.A. Hassanean, A.K. Ibrahim, A.F. Mohammed, S. Fayez, A.M. Hayallah, K. Yamada, F.A. Behery, M.M. Al-Sanea. S.I. Alzarea, G. Bringmann, S.A. Ahmed, U.R. Abdelmohsen; New Cytotoxic Natural Products from the Red Sea Sponge Stylissa carteri; Mar. Drugs 2020, 18, 241-253 (https://doi.org/10.3390/md18050241). |
744) | S. Fayez, T. Bruhn, D. Feineis, L. Aké Assi, S. Awale, G. Bringmann; Ancistrosecolines A-F, Unprecedented seco-Naphthylisoquinoline Alkaloids from the Roots of Ancistrocladus abbreviatus, with Apoptosis-Inducing Potential against HeLa Cancer Cells;J. Nat. Prod. 2020, 83, 1139-1151 (https://doi.org/10.1021/acs.jnatprod.9b01168). |
2019
2018
2017
2016
708) | R. Seupel, B. Hertlein-Amslinger, T. Gulder, P. Stawski, M. Kaiser, R. Brun, G. Bringmann; Directed Synthesis of All Four Pure Stereoisomers of the N,C-Coupled Naphthylisoquinoline Alkaloid Ancistrocladinium A; Org. Lett. 2016, 18, 6508-6511. | |
---|---|---|
707) | A. Goel, V. Kumar, Y. Hemberger, F.V. Singh, P. Nag, M. Knauer, R. Kant, R. Raghunandan, P.R. Maulik, G. Bringmann; Rotationally Hindered Biphenyls and Terphenyls: Synthesis, Molecular Dynamics, and Configurational Assignment; J. Org. Chem. 2016, 81, 10721-10732. | |
706) | M. Arrowsmith, D. Auerhammer, R. Bertermann, H. Braunschweig, G. Bringmann, M. A. Celik, R. D. Dewhurst, M. Finze, M. Grüne, M. Hailmann, T. Hertle, I. Krummenacher; Generation of Dicoordinate Boron(I) Units by Fragmentation of a Tetra-Boron(I) Molecular Square; Angew. Chem., Int. Ed. 2016, 55, 14464-14468; Angew. Chem. 2016, 128, 14680-14684. | |
705) | G. Bringmann, R. Seupel, D. Feineis, G. Zhang, M. Xu, J. Wu, M. Kaiser, R. Brun, E.-J. Seo, Th. Efferth; Ancistectorine D, a naphthylisoquinoline alkaloid with antiprotozoal and antileukemic activities, and further 5,8'- and 7,1'-linked metabolites from the Chinese liana Ancistrocladus tectorius; Fitoterapia 2016, 115, 1-8. | |
704) | G. Bringmann, A. Irmer, T. Büttner, A. Schaumlöffel, G. Zhang, R. Seupel, D. Feineis, K. Fester; Axially Chiral Dimeric Naphthalene and Naphthoquinone Metabolites, from Root Cultures of the West African Liana Triphyophyllum peltatum; J. Nat. Prod. 2016, 79, 2094-2103. | |
703) | S.K. Bose, S. Brand, H. Oluwatola Omoregie, M. Haehnel, J. Maier, G. Bringmann, T.B. Marder; Highly Efficient Synthesis of Alkylboronate Esters via Cu(II)-Catalyzed Borylation of Unactivated Alkyl Bromides and Chlorides in Air; ACS Catalysis 2016, 6, 8332-8335. | |
702) | W. Li, L. Shen, T. Bruhn, P. Pedpradab, J. Wu, G. Bringmann; Trangmolins A-F with an Unprecedented Structural Plasticity of the Rings A and B: New Insight Into Limonoid Biosynthesis; Chem. Eur. J. 2016, 22, 11719-11727. | |
701) | G. Bringmann, M. Xu, R. Seupel, D. Feineis, J. Wu; Ancistrotectoquinones A and B, the First Quinoid Naphthylisoquinoline Alkaloids, from the Chinese Liana Ancistrocladus tectorius; Nat. Prod. Commun. 2016, 11, 971-976. | |
700) | G. Bringmann, N. Manchala, T. Büttner, B. Hertlein-Amslinger, R. Seupel; First Atroposelective total Synthesis of Enantiomerically Pure Ancistrocladidine and Ancistrotectorine; Chem. Eur. J. 2016, 22, 9792-9796. | |
699) | G. Bringmann, C. Steinert, D. Feineis, V. Mudogo, J. Betzin, C. Scheller; HIV-inhibitory michellamine-type dimeric naphthylisoquinoline alkaloids from the Central African liana Ancistrocladus congolensis; Phytochemistry 2016, 128, 71-81. | |
698) | G. Bringmann, A. Irmer, S. Rüdenauer, J. Mutanyatta-Comar, R. Seupel, D. Feineis; 5'-O-Methyldioncophylline D, a 7,8'-coupled naphthylisoquinoline alkaloid from callus cultures of Triphyophyllum peltatum, and its biosynthesis from a late-stage tetrahydroisoquinoline precursor; Tetrahedron 2016, 72, 2906-2912. | |
697) | G. Bringmann; Sorbicillacton A - eine chemische Schnitzeljagd; in Naturstoff-Forschung, Vorbild Natur (Ed. DECHEMA e.V.), Frankfurt, 2016, 291-311. | |
696) | D. T. Tshitenge, K. Ndjoko Ioset, J. N. Lami, J. Ndelo-di-Phanzu, J.-P. Mufusama, G. Bringmann; Rational quality assessment procedure for less-investigated herbal medicines: case of a Congolese antimalarial drug with an analytical report; Fitoterapia 2016, 110, 189-195 (DOI: 10.1016/j.fitote.2016.03.012). | |
695) | E. Sawatzky, S. Wehle, B. Kling, J. Wendrich, G. Brinmgann, C. Sotriffer, J. Heilmann, M. Decker; Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode; J. Med. Chem. 2016, 59, 2067-2082. | |
694) | A. C. Gehrold, T. Bruhn, G. Bringmann; Axial, Helical, and Planar Chirality in Directly Linked Basket-Handle Porphyrin Arrays; J. Org. Chem. 2016, 81, 1075-1088. |
2015
693) | A. C. Gehrold, T. Bruhn, H. Schneider, U. Radius, D. Schmidt, G. Bringmann; Monomeric Chiral and Achiral Basket-Handle Porphyrins: Synthesis, Structural Features, and Arrested Tautomerism; J. Org. Chem. 2015, 80, 12359-12378. | |
---|---|---|
692) | D. C. G. Götz, A. C. Gehrold, S. J. Dorazio, P. Daddario, L. Samankumara, G. Bringmann, C. Brückner, T. Bruhn; Indaphyrins and Indachlorins: Optical and Chiroptical Properties of a Family of Helimeric Porphyrinoids; Eur. J. Org. Chem. 2015, 18, 3913-3922. | |
691) | M. Hans, M. Charpentier, V. Huch, J. Jauch, T. Bruhn, G. Bringmann, D. Quandt; Stereoisomeric Composition of Natural Myrtucommulone A; J. Nat. Prod. 2015, 78, 2381-2389. | |
690) | W. Li, Z. Jiang, L. Shen, P. Pedpradab, T. Bruhn, J. Wu, G. Bringmann; Antiviral Limonoids Including Khayanolides from the Trang Mangrove Plant Xylocarpus moluccensis; J. Nat. Prod. 2015, 78, 1570–1578. | |
689) | Y. Hemberger, G. Zhang, R. Brun, M. Kaiser, G. Bringmann; Highly Antiplasmodial Non-Natural Oxidative Products of Dioncophylline A: Synthesis, Absolute Configuration, and Conformational Stability; Chem. Eur. J. 2015, 21, 14507-14518. | |
688) | M.D. Lewis, J. Behrends, C. Sá e Cunha, A.M. Mendes, F. Lasitschka, J.M. Sattler, K. Heiss, T.W.A. Kooij, M. Prudêncio, G. Bringmann, F. Frischknecht, A.-K. Müller; Chemical Attenuation of Plasmodium in the Liver Modulates Severe Malaria Disease Progression; J. Immunol. 2015, 194, 4860-4870. | |
687) | A. C. Gehrold, T. Bruhn, H. Schneider, U. Radius, G. Bringmann; Chiral and Achiral Basket-Handle Porphyrins: Short Synthesis and Stereostructures of These Versatile Building Blocks; Org. Lett. 2015, 17, 210-213. | |
686) | A. Ponte-Sucre, H. Bruhn, T. Schirmeister, A. Cecil, C. R. Albert, C. Buechold, M. Tischer, S. Schlesinger, T. Goebel, A. Fuss, D. Mathein, B. Merget, C. A. Sotriffer, A. Stich, G. Krohne, M. Engstler, G. Bringmann, U. Holzgrabe; Anti-trypanosomal activities and structural chemical properties of selected compound classes; Parasitol. Res. 2015, 114, 501-512. | |
685) | A. Cecil, K. Ohlsen, T. Menzel, P. Francois, J. Schrenzel, A. Fischer, K. Doerries, M. Selle, M. Lalk, J. Hantzschmann, M. Dittrich, C. Liang, J. Bernhardt, T. A. Oelschlaeger, G. Bringmann, H. Bruhn, M. Unger, A. Ponte-Sucre, L. Lehmann, T. Dandekar; Modelling antibiotic and cytotoxic isoquinoline effects in Staphylococcus aureus, Staphylococcus epidermidis and mammalian cells; Int. J. Med. Microbiol. 2015, 305, 96-109. |
2014
2013
679) | J. Li, M.-Y. Li, T. Bruhn, F. Z. Katele, Q. Xiao, P. Pedpradab, J. Wu, G. Bringmann; Thaixylomolins A–C: Limonoids Featuring Two New Motifs from the Thai Xylocarpus moluccensis; Org. Lett. 2013, 15, 3682–3685. |
---|---|
678) | P. Jetter, C. Steinert, M. Knauer, G. Zhang, T. Bruhn, J. Wiese, J. F. Imhoff, H.-P. Fiedler, G. Bringmann; New bhimamycins from Streptomyces sp. AK 671; J. Antibiot. 2013, published online, DOI:10.1038/ja.2013.82. |
677) | Y. Hemberger, J. Xu, V. Wray, P. Proksch, J. Wu, G. Bringmann; Pestalotiopens A and B: Stereochemically Challenging Flexible Sesquiterpene-Cyclopaldic Acid Hybrids from Pestalotiopsis sp.; Chem. Eur. J. 2013, 19, 15556-15564. |
676) | G. Bringmann, B. K. Lombe, C. Steinert, K. N. Ioset, R. Brun, F. Turini, G. Heubl, V. Mudogo; Mbandakamines A and B, Unsymmetrically Coupled Dimeric Naphthylisoquinoline Alkaloids, from a Congolese Ancistrocladus Species; Org. Lett. 2013, 15, 2590-2593. |
675) | M. Lödige, M. D. Lewis, E. S. Paulsen, H. L. Esch, G. Pradel, L. Lehmann, R. Brun, G. Bringmann, A.-K. Mueller; A primaquine–chloroquine hybrid with dual activity against Plasmodium liver and blood stages; Int. J. Med. Microbiol. 2013, 303, 539-547. |
674) | M. Baunach, L. Ding, T. Bruhn, G. Bringmann, C. Hertweck; Regiodivergent N-C and N-N Aryl Coupling Reactions of Indoloterpenes and Cycloether Formation Mediated by a Single Bacterial Flavoenzyme; Angew. Chem. 2013, 125, 9210-9213; Angew. Chem. Int. Ed. 2013, 52, 9040-9043. |
673) | G. Bringmann, D. Hager, A. Schaumlöffel, M. Groh, A. Speicher; Enantiopure isoplagiochin C by directed deracemization through axis-to-axis chirality transfer; Tetrahedron: Asymmetry 2013, 24, 575-581. |
672) | N. Jansen, B. Ohlendorf, A. Erhard, T. Bruhn, G. Bringmann, J.F. Imhoff; Helicusin E, Isochromophilone X and Isochromophilone XI: new chloroazaphilones produced by the fungus Bartalinia robillardoides strain LF550; Marine Drugs 2013, 11, 800-816. |
671) | L. K. Blusch, Y. Hemberger, K. Pröpper, B. Dittrich, F. Witterauf, M. John, G. Bringmann, C. Brückner, F. Meyer; Siamese-Twin Porphyrin: A Pyrazole-Based Expanded Porphyrin of Persistent Helical Conformation (VIP and Cover); Chem. Eur. J. 2013, 19, 5868–5880. |
670) | G. Bringmann, K. Thomale, S. Bischof, C. Schneider, M. Schultheis, T. Schwarz, H. Moll, U. Schurigt; A Novel Leishmania major Amastigote Assay in 96-Well Format for Rapid Drug Screening and its Use for the Discovery of a New Class of Leishmanicidal Quinolinium Salts; Antimicrob. Agents Chemother. 2013, 57, 3003-3011. |
669) | E.C. Tatsis, A. Schaumlöffel, A.C. Warskulat, G. Massiot, B. Schneider, G. Bringmann; Nudicaulins, Yellow Flower Pigments of Papaver nudicaule: Revised Constitution and Assignment of Absolute Configuration; Org. Lett. 2013, 15, 156-159. |
668) | F. Koch, M. Kullmann, U. Selig, P. Nuernberger, D.C.G. Goetz, G. Bringmann, T. Brixner; Coherent two-dimensional electronic spectroscopy in the Soret band of a chiral porphyrin dimer; New J. Phys. 2013, 15, 025006 (DOI:10.1088/1367-2630/15/2/025006). |
667) | T. Bruhn, Y. Hemberger, A. Schaumlöffel, G. Bringmann; SpecDis: Quantifying the Comparison of Calculated and Experimental Electronic Circular Dichroism Spectra; Chirality 2013, 25, 243-249. |
666) | G. Bringmann, G. Zhang, T. Ölschläger, A. Stich, J. Wu, M. Chatterjee, R. Brun; Highly Selective Antiplasmodial Naphthylisoquinoline Alkaloids from Ancistrocladus tectorius; Phytochemistry 2013, 91, 220-228. |
665) | G. Bringmann, G. Zhang, T. Büttner, G. Bauckmann, T. Kupfer, H. Braunschweig, R. Brun, V. Mudogo; Jozimine A2: The First Dimeric Dioncophyllaceae-Type Naphthylisoquinoline Alkaloid, with Three Chiral Axes and High Antiplasmodial Activity; Chem. Eur. J, 2013, 19, 916-923. |
2012
664) | M. Groh, D. Meidlinger, G. Bringmann, A. Speicher; Atroposelective Heck Macrocyclization: Enantioselective Synthesis of Bis(bibenzylic) Natural Products; Org. Lett., 2012, 14 , 4548–4551. |
---|---|
663) | A. Goel, A. Kumar, Y. Hemberger, A. Raghuvanshi, R. Jeet, G. Tiwari, M. Knauer, J. Kureel, A. K. Singh, A. Gautam, R. Trivedi, D. Singh, G. Bringmann; Synthesis, optical resolution, absolute configuration, and osteogenic activity of cis-pterocarpans; Org. Biomol. Chem., 2012, 10, 9583-9592. |
662) | A. Schaumlöffel, M. Groh, A. Speicher, G. Bringmann; Stereochemical Assignment of Cyclic Bisbibenzyl by HPLC-CD on a Chiral Phase and Quantum-Chemical CD Calculations; Eur. J. Org. Chem. 2012, 6878-6887. |
661) | J. Li, M.-Y. Li, T. Bruhn, D. C.G. Götz, Q. Xiao, T. Satyanandamurty, J. Wu, G. Bringmann; Andhraxylocarpins A-E: Structurally Intriguing Limonoids from Mangroves, Xylocarpus granatum and Xylocarpus moluccensis, Collected in the Estuaries of Andhra Pradesh; Chem. Eur. J., 2012, 18, 14342–14351. |
660) | C. Almeida, Y. Hemberger, S. Bouhired, L. Natesan, S. Kehraus, K. Dimas, M. Gütschow, G. Bringmann, G.M. König; Marilines A-D, Novel Phthalimidines from the Sponge-Derived Fungus Stachylidium sp.; Chem. Eur. J. 2012, 18, 8827-8834. |
659) | M. Kullmann, A. Hipke, P. Nuernberger, T. Bruhn, D. C.G. Goetz, M. Sekita, D.M. Guldi, G. Bringmann, T. Brixner; Ultrafast exciton dynamics after Soret- or Q-band excitation of a directly ß,ß'-linked bisporphyrin; PhysChemChemPhys 2012, 14, 8038-8050. ("Themed Issue on Ultrafast Chemical Dynamics") |
658) | B. Messi, K. Ndjoko Ioset, B. Hertlein-Amslinger, G. Bringmann, A.M. Lannang, A.E. Nkengfack, J.-L. Wolfender, K. Hostettmann, G. Bringmann; Preussianone, a New Flavanone-Chromone Biflavonoid from Garcinia preussii Engl.; Molecules 2012, 17, 6114-6125. |
657) | U.R. Abdelmohsen, A. Philippe, G. Zhang, W. Schmitz, S.M. Pimentel- Elardo, B. Hertlein-Amslinger, U. Hentschel, G. Bringmann; Cyclodysidins A-D, cyclic lipopeptides from the marine sponge-derived Streptomyces strain RV15; Tetrahedron Lett. 2012, 53, 23-29. |
656) | G. Bringmann, D. Goetz T. Bruhn; The Online Stereoanalysis of Chiral Compounds by HPLC-ECD Coupling in Combination with Quantum-Chemical Calculations; in Comprehensive Chiroptical Spectroscopy (N. Berova, P. Polavarapu, K. Nakanishi, R.W. Woody, Eds.), Vol. 2, John Wiley & Sons, 2012, pp. 355-386. |
2011
655) | S. M. Pimentel-Elardo, V. Buback, T. A. M. Gulder, T. S. Bugni, J. Reppart, G. Bringmann, C. M. Ireland, T. Schirmeister, U. Hentschel; New Tetromycin Derivatives with Anti-Trypanosomal and Protease Inhibitory Activities; Mar. Drugs 2011, 9, 1682-1697.
|
---|---|
654) | S. Loesgen, T. Bruhn, G. Bringmann, K. Meindl, I. Dix, B. Schulz, A. Zeeck; (+)-Flavipucine, the Missing Member of the Pyridione Epoxide Family of Fungal Antibiotics; Eur. J. Org. Chem. 2011, 5156–5162.
|
653) | C. Brückner, D.C.G. Götz, S.P. Fox, C. Ryppa, J.R. McCarthy, T. Bruhn, H.W. Daniell, S. Banerjee, P. Daddario, M. Zeller, R.W. Boyle, G. Bringmann; Helimeric Porphyrinoids: Stereostructure and Chiral Resolution of meso-Tetraarylmorpholinochlorins; J. Am. Chem. Soc. 2011, 133, 8740-8752.
|
652) | A. Cecil, C. Rikanovic, K. Ohlsen, C. Liang, T. Ölschläger, T. Gulder, G. Bringmann, U. Holzgrabe, M. Unger, T. Dandekar; Modelling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in S. aureus, S. epidermidis and human cells; Genome Biol. 2011, 12, R24, open access.
|
651) | A. Goel, D. Verma, R. Pratap, G. Taneja, Y. Hemberger, M. Knauer, R. Raghunandan, P.R. Maulik, V.J. Ram, G. Bringmann; Partially Hydrogenated 8- Oxa[5]helicenes and [5]Helicenes – Synthesis, Structure, and Dynamics; Eur. J. Org. Chem. 2011, 2940-2947.
|
650) | H. Frank, L. Campanella, F. Dondi, E. Leitner, J. Mehlich, G. Rossi, K. Ndjoko, G. Bringmann; Ethics, Chemistry and Education for the Environment; Angew. Chem. 2011, 123. 8632-8641; Angew. Chem. Int. Ed. 2011, 50, 8445-8458.
|
649) | G. Bergner, C. Albert, M. Schilling, G. Bringmann, T. Schirmeister, B. Dietzek, S. Schlücker, J. Popp; Quantitative CARS microscopy and Raman microspectroscopy of C-deuterated drugs;
|
648) | E. Kugelmann, C.R. Albert, G. Bringmann, U. Holzgrabe; Fenton‘s oxidation: a tool for the investigation of potential drug metabolites; J. Pharm. Biomed. Anal. 2011, 54, 1047-1058.
|
647) | G. Bringmann, T.A.M. Gulder, T. Gulder; Asymmetric Synthesis of (M)- 2-Hydroxymethyl-1(2-Hydroxy-4,6- dimethylphenyl)naphthalene via a Configurationally Unstable Biaryl Lactone; Org. Synth. 2011, 88, 70-78.
|
646) | L. Liu, T. Bruhn, L. Guo, D. C. G. Götz, R. Brun, A. Stich, Y. Che, G. Bringmann; Chloropupukeanolides C–E, Cytotoxic Pupukeanane Chlorides with a Spiroketal Skeleton from Pestalotiopsis fici; Chem. Eur. J. 2011, 17, 2604-2613 (with Cover Picture).
|
645) | G. Bringmann, D. Wunderlich; Sorbicillactone A – a Chemical Paper Chase; in Inspired by Nature - State and Perspektives of Natural Products Research in Germany (Eds. G. Bringmann, S. Grabley, J. Piel, D. Sell, T. Spellig, C. Steinbach), DECHEMA e.V., Frankfurt; 2011, 36-43.
|
644) | G. Bringmann, G. Zhang. A. Hager, M. Moos, A. Irmer, R. Bargou, M. Chatterjee; Antitumoral activities of dioncoquinones B and C and related naphthoquinones gained from total synthesis or isolation from plants; Eur. J. Med. Chem. 2011, 46, 5778-5789. |
643) | E.M. Finnigan, R. Rein, N. Solladié, K. Dahms, D.C.G. Götz, G. Bringmann, M.O. Senge; Synthesis and ligand binding properties of triptycene-linked porphyrin arrays; Tetrahedron 2011, 67, 1126-1134.
|
642) | L. Du, J. Ai, D. Li, T. Zhu, Y. Wang, M. Knauer, T. Bruhn, H. Liu, M. Geng, Q. Gu, G. Bringmann; Aspergiolides C and D: Spirocyclic Aromatic Polyketides with Potent Protein Kinase c-Met Inhibitory Effects; Chem. Eur. J. 2011, 17, 1319–1326.
|
641) | C. Büchold, Y. Hemberger, C. Heindl, A. Welker, B. Degel, T. Pfeuffer, P. Staib, S. Schneider, P. J. Rosenthal, J. Gut, J. Morschhäuser, G. Bringmann, T. Schirmeister; New cis-Configured Aziridine-2-carboxylates as Aspartic Acid Protease Inhibitors; ChemMedChem 2011, 6, 141–152.
|
640) | G. Bringmann, T. Gulder, T. A. M. Gulder, M. Breuning; Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products; Chem. Rev. 2011, 111, 563-639.
|
639) | G. Bringmann, B. Hertlein-Amslinger, I. Kajahn, M. Dreyer,R. Brun, H. Moll, A. Stich, K. Ndjoko Ioset, W. Schmitz, L. Ngoc; Phenolic analogs of the N,C-coupled naphthylisoquinoline alkaloid ancistrocladinium A, from Ancistrocladus cochinchinensis, (Ancistrocladaceae), with improved antiprotozoal activities; Phytochemistry 2011, 72, 89-93.
|
638) | K. Gebhardt, S.W. Meyer, J. Schinko, A. Zeeck, G. Bringmann, H.-P. Fiedler; Phenalinolactones A–D, novel terpenoglycoside antibiotics from Streptomyces sp. Tü 6071; J. Antibiot. 2011, 64, 229-232.
|
2010
637) | C.A. Schmidt, R. Murillo, T. Bruhn, G. Bringmann, M. Goettert, B. Heinzmann, V. Brecht, S. Laufer, I. Merfort; Catechin Derivatives from Parapiptadenia rigida with in vitro Wound-Healing Properties; J. Nat. Prod. 2010, 73, 2035–2041.
|
---|---|
636)* | G. Bringmann , M. Lödige , A.-K. Müller , M. Lewis , G. Pradel , H. Moll , U. Schurigt , L. Lehmann , R. Brun ; Hybridverbindungen aus 4- und 8-Aminochinolinen zur prophylaktischen und therapeutischen Behandlung von Malaria und anderen parasitären Erkrankungen; German Patent Application (DE ), filed 14.10.0210.
|
635) | G. Bringmann, G. Lang, T. Bruhn, K. Schäffler, S. Steffens, R. Schmaljohann, J. Wiese, J. F. Imhoff; Sorbifuranones A-C, Sorbicillinoid Metabolites From Penicillium Strains Isolated From Mediterranean Sponges,Tetrahedron 2010, 66, 9894-9901.
|
634)* | G. Bringmann , M. Lödige , A. Kronhardt , C. Beitzinger , H. Barth , R. Benz ; Aminoquinolinium Salts; European Patent Application (DE ), filed 29.09.2010.
|
633) | A. Jindaprasert, S. Samappito, K. Springob, J. Schmidt, T. Gulder, W. De-Eknamkul, G. Bringmann, T.M. Kutchan; In Vitro Plants, Callus and Root Cultures of Plumbago indica and Their Biosynthetic Potential for Plumbagin;
|
632) | G. Fan, Z. Li, Y. Zeng, M. Xu, Z. Deng, T. Bruhn, H. Bruhn, J. Morschhäuser, G. Bringmann, W. Lin; Baculiferins A-O, O-Sulfated Pyrrole Alkaloids with anti-HIV-1 Activity, from the Chinese Marine Sponge Iotrochota baculifera;
|
631) | G. Bringmann, S. K. Bischof, S. Müller, T. Gulder, C. Winter, A. Stich, H. Moll, M. Kaiser, R. Brun, J. Dreher, K. Baumann; QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids; Eur. J. Med. Chem. 2010, 45, 5370-5383.
|
630) | G. Bringmann, T. Gulder, B. Hertlein, Y. Hemberger, F. Meyer; Total Synthesis of the N,C-Coupled Naphthylisoquinoline Alkaloids Ancistrocladinium A and B, and Related Analogues; J. Am. Chem. Soc. 2010, 132, 1151-1158.
|
629) | A. Hansjakob, S. Bischof, G. Bringmann, M. Riederer, U. Hildebrand; Very-long chain aldehydes promote in vitro prepenetration processes of Blumeria graminis in a dose and chain-length dependent manner; New Phytologist 2010, 188, 1039-1054.
|
628) | M. Xu, T. Bruhn, B. Hertlein, R. Brun, A. Stich, J. Wu, G. Bringmann; Shuangancistrotectorines A-E, Dimeric Naphthylisoquinoline Alkaloids with Three Chiral Biaryl Axes, from the Chinese Plant Ancistrocladus tectorius; Chem. Eur. J. 2010, 16, 4206-4216 (with cover picture).
|
627) | H. Meimberg, H. Rischer, F. Turini, V. Chamchumroon, M. Dreyer, M. Sommaro, G. Bringmann, G. Heubl; Evidence for species differentiation within the Ancistrocladus tectorius complex (Ancistrocladaceae) in Southeast Asia: A molecular approach; Plant Syst. Evol. 2010, 284, 77-98.
|
626) | G. Heubl, F. Turini, V. Mudogo, I. Kajahn, G. Bringmann; Ancistrocladus ileboensis (D.R.Congo), a new liana with unique alkaloids; Pl. Ecol. Evol. 2010, 143, 63-69.
|
625) | K. Rembold, S. Poppinga, O. Kriesten, A. Irmer, H. Rischer, G. Bringmann; Triphyophyllum peltatum (Dioncophyllaceae) an Observations on its Carnivory; Carniv. Pl. Newslett. 2010, 39, 71-77 (with cover picture).
|
624) | U. Hentschel, G. Bringmann; Marine Schwämme - Füllhorne der Meere; Pharmazie uns. Zeit 2010, 39, 62-66.
|
623) | A. Ponte-Sucre, T. Gulder, T.A.M. Gulder, G. Vollmers, G. Bringmann, H. Moll; Alterations to the structure of Leishmania major induced by N-arylisoquinolines correlate with compound accumulation and disposition; J. Med. Microbiol. 2010, 59, 69-75. (with cover picture)
|
622) | J. Moldenhauer, D.C.G. Götz, C.R. Albert, S.K. Bischof, K. Schneider, R.D. Süssmuth, M. Engeser, H. Gross, G. Bringmann, J. Piel; The Final Steps of Bacillaene Biosynthesis in Bacillus amyloliquefaciens FZB42: Direct Evidence for beta,gamma-Dehydration by a trans- AT Polyketide Synthase; Angew. Chem. 2010, 122, 1507 - 1509; Angew. Chem. Int. Ed. 2010, 49, 1465-1467.
|
2009
621) | D.C.G. Götz, T. Bruhn, O. Senge, G. Bringmann; Synthesis and Stereochemical Characterization of Highly Unsymmetric ß,meso-Linked Porphyrin Arrays; J. Org. Chem. 2009, 74, 8005–8020. (‚Featured Article’, with cover picture). |
---|---|
620) | G. Bringmann, A. Irmer, D. Feineis, T.A.M. Gulder, H.- P. Fiedler; Convergence in the Biosynthesis of Polyketide-Derived Natural Products from Plants, Fungi, and Bacteria; Phytochemistry (special issue ‚Evolution of Metabolic Diversity’) 2009, 70, 1776-1786. |
619) | A. Speicher, M. Groh, J. Zapp, A. Schaumlöffel, M. Knauer, G. Bringmann; A Synthesis-Driven Structure Revision of „Plagiochin E“, a Highly Bioactive Bisbibenzyls; Synlett 2009, 1852-1858. |
618) | G. Bringmann, K. Maksimenka, T. Bruhn, M. Reichert, T. Harada, R. Kuroda; Quantum chemical CD calculations of dioncophylline A in the solid state;Tetrahedron 2009, 65, 5720-5728. |
617) | F. Tribl, E. Asan, T. Arzberger, T. Tatschner, E. Langenfeld, H.E. Meyer, G. Bringmann, P. Riederer, M. Gerlach, K. Markus; Identification of L-ferritin in neuromelanin granules of the human substantia nigra – a targeted proteomics approach; Mol. Cell. Proteomics 2009, 8, 1832-1838. |
616) | J. Bunzen, T. Bruhn, G. Bringmann, A. Lützen; Synthesis and Helicate Formation of a New Family of BINOL-Based Bis(bipyridine) Ligands; J. Am. Chem. Soc. 2009, 131, 3621–3630.
|
615) | G. Bringmann, T. Bruhn, K. Maksimenka, Y. Hemberger; The Assignment of Absolute Stereostructures by Quantum Chemical Circular Dichroism Calculations; Eur. J. Org. Chem. 2009, 2717 - 2727. |
614) | A. Ponte-Sucre, T. Gulder, A. Wegehaupt, C. Albert, C. Rikanovic, L. Schaeflein, A. Frank, M. Schultheis, M. Unger, U. Holzgrabe, G. Bringmann, H. Moll; Structure- Activity Relationship and Studies on the Molecular Mechanism of Leishmanicidal N,C-Coupled Arylisoquinolinium Salts; J. Med. Chem. 2009, 52, 626–636. |
613) | T.S. Balaban, A.D. Bhise, G. Bringmann, J. Bürck, C. Chappaz-Gillot, A. Eichhöfer, D. Fenske, D. Götz, M. Knauer, T. Mizoguchi, D. Mössinger, M. Reichert, H. Roesner, C. Roussel, M. Schraut, H. Tamiaki, N. Vanthuyne; Mimics of the self-assembling chlorosomal bacteriochlorophylls: Regio- and stereoselective synthesis and stereoanalysis of acyl-(1- hydroxyalkyl)porphyrins; J. Am. Chem. Soc. 2009, 131, 14480–14492. |
612) | G. Bringmann, T.A.M. Gulder, A. Hamm, M. Goodfellow, H.-P. Fiedler; Multiple convergence in polyketide biosynthesis: a third folding mode to the anthraquinone chrysophanol, involving a bicyclic diketone; Chem. Commun. 2009, 6810-6812. |
611) | Z. Yunt, K. Reinhardt, A. Li, M. Engeser, H.-M. Dahse, M. Gütschow, T. Bruhn, G. Bringmann, J. Piel; Cleavage of Four Carbon-Carbon Bonds during Biosynthesis of the Griseorhodin A Spiroketal Pharmacophore; J. Am. Chem. Soc. 2009, 131, 2297-2305.
|
2008
610) | G. Bringmann, D.C.G. Götz, T.A.M. Gulder, T.H. Gehrke, T. Bruhn, T, Kupfer, K. Radacki, H. Braunschweig, A. Heckmann, C. Lambert; Axially Chiral ß,ß’-Bisporphyrins: Synthesis and Configurational Stability Tuned by the Central Metals; J. Am. Chem. Soc. 2008, 130, 17812–17825.
| |||||
609) | S. M. Pimentel-Elardo, T.A.M. Gulder, U. Hentschel, G. Bringmann; Cebulactams A1 and A2, new macrolactams isolated from Saccharopolyspora cebuensis, the first obligate marine strain of the genus Saccharopolyspora; Tetrahedron Lett. 2008, 49, 6889-6892.
| |||||
608) | K.F. Schwedhelm, M. Horstmann, J.H. Faber, Y. Reichert, M. Büchner, G. Bringmann, C. Faber; Spin state of chloroquine-heme complexes: formation of a hemin tetramer adduct; Open Spectrosc. J. 2008, 2, 10-18. | |||||
607) | G. Bringmann, S. Rüdenauer, A. Irmer, T. Bruhn, R. Brun, T. Heimberger, T. Stühmer, R. Bargou, M. Chatterjee; Antitumoral Dioncoquinones and Ancistroquinones from cell cultures of Triphyophyllum peltatum (Dioncophyllaceae) and Ancistrocladus abbreviatus (Ancistrocladaceae); Phytochemistry 2008, 69, 2501-2509.
| |||||
606)* | G. Bringmann, S. Rüdenauer, A. Irmer, R. Brun, Chatterjee, R. Bargou; Dioncochinone, Ancistrochinone und davon abgeleitete Verbindungen, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE ), filed 06.02.2008.
| |||||
605) | R. Deeken, P. Ache, I. Kajahn, C. J. Klinkenberg, G. Bringmann, R. Hedrich; Identification of Arabidopsis thaliana phloem RNAs provides a search criterion for phloem-based transcripts hidden in complex data sets of microarray experiments; Plant Journal 2008, 55, 746-759.
| |||||
604) | G. Bringmann, S. Rüdenauer, T. Bruhn, L. Benson; Total synthesis of the antimalarial naphthylisoquinoline alkaloid 5-epi-4’-O-demethylancistrobertsonine C by asymmetric Suzuki cross coupling reaction; Tetrahedron 2008, 64, 5563-5568.
| |||||
603) | G. Bringmann, A. Irmer; Acetogenic Anthraquinones: Biosynthetic Convergence and Chemical Evidence of Enzymatic Cooperation in Nature; Phytochem. Rev. 2008, 7, 499-511.
| |||||
602) | G. Bringmann, T.A.M. Gulder, M. Reichert, T. Gulder; The Online Assignement of the Absolute Configuration of Natural Products: HPLC-CD in Combination with Quantum Chemical Calculations; Chirality 2008, 20, 628-642.
| |||||
601) | U. Kiehne, T. Bruhn, G. Schnakenburg, R. Fröhlich, G. Bringmann, A. Lützen; Synthesis, resolution, and Absolute Configuration of Difunctionalized Tröger´s Base Derivatives; Chem. Eur. J. 2008, 14, 4246-4255.
| |||||
600) | G. Bringmann, B. Abegaz, M. Knauer, J. Mutanyatta; Knipholone and related 4-phenylanthraquinones, a young class of structurally, pharmacologically, and biosynthetically intriguing natural products; Nat. Prod. Rep. 2008, 25, 696-718.
| |||||
599) | G. Bringmann, J. Spuziak, J.H. Faber, T. Gulder, I. Kajahn, M. Dreyer, G. Heubl, R. Brun, V. Mudogo; Six naphthylisoquinoline alkaloids and a related benzopyranone from a Congolese Ancistrocladus species related to Ancistrocladus congolensis; Phytochemistry 2008, 69, 1065-1075.
| |||||
598) | G. Bringmann, J. Mutanyatta-Comar, K. Maksimenka, J.M. Wanjohi, M. Heydenreich, R. Brun, W.E.G. Müller, M.G. Peter, J.O. Midiwo, A. Yenesew; Joziknipholones A and B, the first dimeric phenylanthracenes, from the roots of Bulbine frutescens; Chem. Eur. J. 2008, 14, 1420-1429.
| |||||
597) | H.-P. Fiedler, A. Dieter, T.A.M. Gulder, I. Kajahn, A. Hamm, G. Payne, M. Goodfellow, W.E.G. Müller, G. Bringmann; Genoketides A1 and A2, new octaketides and biosynthetic intermediates of chrysophanol produced by Streptomyces sp. AK 671;
| |||||
596) | J. Wu, S. Zhang, Q. Xiao, H. Ding, T. Bruhn, G. Bringmann; Xylogranatins F-R: Antifeedants from the Chinese Mangrove, Xylocarpus granatum, Suggesting a New Biogenetic Pathway to Tetranortriterpenoids; Chem. Eur. J. 2008, 14, 1129-1144.
| |||||
595) | G. Bringmann, R. Bruhn, M. Kaiser, S. Neumann; Synthesis and antiprotozoal activities of simplified analogs of naphthylisoquinoline alkaloids; Eur. J. Med. Chem.2008, 43, 32-34.
| |||||
594) | G. Bringmann, M. Reichert, Y. Hemberger; The absolute configuration of streptonigrin; Tetrahedron 2008, 64, 515-521.
| |||||
593) | V. Zabka, U. Hildebrand, M. Stangl, G. Vogg, G. Bringmann, M. Riederer; The wax effect: pre-prenetration process of powdery mildew affected by host surface properties; New Phytologist 2008, 177, 215-263. |
2007
592) | A. Goel, F.V. Singh, V. Kumar, M. Reichert, T.A.M. Gulder, G. Bringmann; Synthesis, Optical Resolution, and Configurational Assignment of Novel Axially Chiral Quateraryls; J. Org. Chem. 2007, 72, 7765-7768.
| |||||
591) | G. Bringmann, Y. Haagen, T. Gulder, T. Gulder, L. Heide; Biosynthesis of the isoprenoid moieties of furanonaphtoquinone I and Endophenazine A in Streptomyces cinnamonensis DSM 1042; J. Org. Chem. 2007, 72, 4198-4204. | |||||
590) | G. Bringmann, K. Maksimenka, J. Mutanyatta-Comar, M. Knauer, T. Bruhn; The absolute axial configurations of knipholone and knipholone anthrone by TDDFT and DFT/MRCI CD calculations: a revision;Tetrahedron 2007, 63, 9810-9824. | |||||
589) | P. Osswald, M. Reichert, G. Bringmann, F. Würthner; Perylene Bisimide Atropisomers – Synthesis, Resolution and Stereochemical Assignment; J. Org. Chem. 2007, 72, 3403-3411.
| |||||
588) | G. Bringmann, T.A.M. Gulder, G. Lang, S. Schmitt, R. Stöhr, J. Wiese, K. Nagel, J.F. Imhoff; Large-Scale Biotechnological Production of the Antileukemic Marine Natrual Product Sorbicillactone A; Marine Drugs 2007, 5, 23-30.
| |||||
587) | A. Charchoglyan, A. Abrahamyan, I. Fujii, Z. Boubakir, T.A.M. Gulder, T.M. Kutchan,H. Vardapetyan, G. Bringmann, Y. Ebizuka, L. Beerhues; Differential accumulation of hyperforin and secohyperforin in Hypericum perforatum tissue cultures; Phytochemistry 2007, 68, 2670-2677. | |||||
586) | X. Yang, T.A.M. Gulder, M. Reichert, C. Tang, C. Ke, Y. Ye, G. Bringmann; Parvistimenis A-D, a new type of dimeric phenylethyl benzoquinones from Stemona parviflora Wright; Tetrahedron, 2007, 63, 4688-4694.
| |||||
585) | L.-F. Tietze, F. Major, I. Schuberth, D.A. Spiegl, B. Krewer, K. Maksimenka, G. Bringmann, J. Magull; Selective Treatment of Cancer: Synthesis, Biological Evaluation, and Structural Elucidation of Novel Analogues of the Antibiotic CC-1065 and the Duocarmycins; Chem. Eur. J. 2007, 13, 4396-4409. | |||||
584) | G. Bringmann, T. F. Noll, M. Dreyer, T. Gulder, M. Grüne, D. Moskau; Polyketide Folding in Higher Plants: Biosynthesis of the Phenylanthraquinone Knipholone; J. Org. Chem. 2007, 72, 3247-3252. | |||||
583) | G. Bringmann, C. M. Gampe, Y. Reichert, T. Bruhn, J.H. Faber, M. Mikyna, M. Reichert, M. Leippe, R. Brun, C. Gelhaus; Synthesis and Pharmacological Evaluation of Fluorescent and Photoactivatable Analogues of Antiplasmodial Naphthylisoquinolines; J. Med. Chem. 2007, 50, 6104-6115. | |||||
582) | K.F. Schwedhelm, M. Horstmann, J.H. Faber, Y. Reichert, G. Bringmann, C. Faber; The novel antimalarial compound dioncophylline C forms a complex with heme in solution; ChemMedChem 2007, 2, 541-548. | |||||
581) | M.C. Kozlowski, E.C. Dugan, E.S. DiVirgilio, K. Maksimenka G. Bringmann; Asymmetric Total Synthesis of Nigerone and ent-Nigerone: Enantioselective Oxidative Biaryl Coupling of Highly Hindered Naphthols; Adv. Synth. Catal. 2007, 349, 583-594. | |||||
580) | M. Xu, G. Gessner, I. Groth, C. Lange, A, Christner, T. Bruhn, Z. Deng, X. Li, S.H. Heinemann, S. Grabley, G. Bringmann, I. Sattler, W. Lin; Shearinines D-K, new indole triterpenoids from an endophytic Penicillium sp. (strain HKI0459) with blocking activity on large-conductance calcium-activated potassium channels; Tetrahedron 2007, 63, 435-444. | |||||
579) | G. Bringmann, J. Mutanyatta, M. Greb, S. Rüdenauer, T. Noll, A. Irmer; Biosynthesis of naphthylisoquinoline alkaloids: synthesis and incorporation of an advanced 13C2-labeled isoquinoline precursor; Tetrahedron 2007, 63, 1755-1761. | |||||
578) | C. Anderle, S. Alt, T. Gulder, G. Bringmann, B. Kammerer, B. Gust, L. Heide; Biosynthesis of clorobiocin: investigation of the transfer and methylation of the pyrrolyl-2-carboxyl moiety; Arch. Microbiol. 2007, 187, 227-237. | |||||
577) | T. Frosch, M. Schmitt, T. Noll, G. Bringmann, K. Schenzel, J. Popp; Ultrasensitive in situ Tracing of the Alkaloid Dioncophylline A in the Tropical Liana Triphyophyllum peltatum by Applying Deep-UV Resonance Raman Microscopy; Anal. Chem. 2007, 79, 986-993. | |||||
576) | G. Bringmann, D. Wunderlich; Sorbicillacton A - eine chemische Schnitzeljagd; in Vorbild Natur, Stand und perspektiven der Naturstoff-Forschung in Deutschland (Eds. G. Bringmann, S. Grabley, J. Piel, D. Sell, T. Spellig, C. Steinbach), DECHEMA e.V., Frankfurt; 2007, 36-43. | |||||
575) | T. Frosch, M. Schmitt, G. Bringmann, W. Kiefer, J. Popp; Structural Analysis of the Anti-Malaria Active Agent Chloroquine under Physiological Conditions; J. Phys. Chem. B 2007, 111, 1815-1822. | |||||
574) | A. Ponte-Sucre, J.H. Faber, T. Gulder, I. Kajahn, S.E.H. Pedersen, M. Schultheis, G. Bringmann, H. Moll; Activities of Naphthylisoquinoline Alkaloids and Synthetic Analogs against Leishmania major; Antimicrob. Agents Chemother. 2007, 51, 188-194.
| |||||
573) | G. Bringmann, T. Gulder, T.A.M. Gulder; Asymmetric Synthesis of Biaryls by the ‘Lactone Method’ in Asymmetric Synthesis – The Essentials (Eds. M. Christmann, S. Bräse), Wiley-VCH, Weinheim; 2007, 246-250. |
2006
572) | J. Hartung, K. Daniel, C. Rummey, G. Bringmann; On the stereoselectivity of 4-penten-1-oxyl radical 5-exo-trig cyclizations; Org. Biomol. Chem. 2006, 4, 4089-4100. | |
571) | G. Bringmann, I. Kajahn, M. Reichert, S.E.H. Pedersen, J.H. Faber, T.Gulder, R. Brun, S.B. Christensen, A. Ponte-Sucre, H. Moll, G. Heubl, V. Mudogo; Ancistrocladinium A and B, the First N,C-Coupled Naphthyldihydroisoquinoline Alkaloids, from a Congolese Ancistrocladus Species; J. Org. Chem. 2006, 71, 9348-9356. | |
570) | G. Bringmann, T.F. Noll, T.A.M. Gulder, M. Grüne, M. Dreyer, C. Wilde, F. Pankewitz, M. Hilker, G.D. Payne, A.L. Jones, M. Goodfellow, H.-P. Fiedler; Different polyketide folding modes converge to an identical molecular architecture; Nature Chem. Biol. 2006, 2, 429-433. | |
569) | K. Ishida, K. Maksimenka , K. Fritzsche, K. Scherlach, G. Bringmann, C. Hertweck; The Boat-Shaped Polyketide Resistoflavin Results from Re-Facial Central Hydroxylation of the Discoid Metabolite Resistomycin; J. Am. Chem. Soc. 2006, 128, 14619-14624. | |
568) | G. Bringmann, S. Rüdenauer, D.C.G. Götz, T.A.M. Gulder, M. Reichert; Axially Chiral Directly ß,ß-Linked Bisporphyrins: Synthesis and Stereostructure; Org. Lett. 2006, 8, 4743-4746. | |
567) | D. Hölscher, M. Reichert, H. Görls, O. Ohlenschläger, G. Bringmann, B. Schneider; Monolaterol, the First Configurationally Assigned Phenylphenanolone Derivative with a Stereogenic Center at C-9, from Monocheria elata; J. Nat. Prod. 2006, 69, 1614-1617. | |
566) | A. Storch, Y.-I. Hwang, G. Bringmann, D. Feineis, S. Ott, R. Brückner, J. Schwarz; Cytotoxicity of chloral-derived ß-carbolines is not specific towards neuronal nor dopaminergic cells; J. Neural Transm. 2006, 113, 1895-1901. | |
565)* | G. Bringmann, T. Gulder, F. Meier, V. Mudogo, H. Moll, A. Ponte-Sucre, R. Brun, A. Stich, J. Morschhäuser, U. Hentschel, W. Ziebuhr; N,C-verknüpfte Naphthylisochinoline und deren Derivate; Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE ), filed 27.09.06; PCT/EP. Issued. | |
564) | F. Tribl, K. Marcus, G. Bringmann, H.E. Meyer, M. Gerlach, P. Riederer; Proteomics in the human brain: sub-proteomes might hold the key to handle brain complexity; J. Neural Transm. 2006, 113, 1041-1054. | |
563) | G. Bringmann, D. Feineis, M. Münchbach, R. God, K. Peters, E.-M. Peters, R. Mössner, K.-P. Lesch; Toxicity and Metabolism of the Chloral-Derived Mammalian Alkaloid 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo) in PC12 Cells; Z. Naturforsch. 2006, 61c, 601-610. | |
562) | P. Kapková, E. Heller, E. Kugelmann, J.H. Faber, G. Bringmann, U. Kessler, G. Folkers, U. Holzgrabe; Random Chemistry as a New Tool for the Generation of Small-Compound Libraries; Arch. Pharm. Chem. Life Sci. 2006, 339, 489-497. | |
561) | M. Sieber, W. Dekant, J.H. Faber, G. Bringmann; Biotransformation and pharmacokinetics of the antiplasmodial naphthylisoquinoline alkaloid dioncophylline A; Xenobiotica 2006, 36, 750-762. | |
560) | G. Bringmann, H. Scharl, K. Maksimenka, K. Radacki, H. Braunschweig, P. Wich, C. Schmuck; Atropodiastereoselective Cleavage of Configurationally Unstable Biaryl Lactones with Amino Acid Esters; Eur. J. Org. Chem. 2006, 4349-4361 (with cover picture). | |
559) | G. Bringmann, D. Feineis, R. Brückner, R. God, C. Grote, W. Wesemann; Synthesis of radiolabelled 1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo), a neurotoxic chloral-derived mammalian alkaloid, and its biodistribution in rats; Eur. J. Pharm. Sci. 2006, 28, 412-422. | |
558) | F. Tribl, K. Marcus, H.E. Meyer, G. Bringmann, M. Gerlach, P. Riederer; Subcellular proteomics reveals neuromelanin granules to be a lysosome-related organelle; J. Neural Transm. 2006, 113, 741-749. | |
557) | M. Scheuermayer, T.A.M. Gulder, G. Bringmann, U. Hentschel; Rubritalea marina gen. nov., sp. nov., a marine representative of the phylum ‘Verrucomicrobia’, isolated from a sponge (Porifera); Int. J. Syst. Evol. Microbiol. 2006, 56, 2119-2124. | |
556) | G. Bringmann, T. Gulder, M. Reichert, F. Meyer; Ancisheynine, the First N,C-Coupled Naphthylisoquinoline Alkaloid: Total Synthesis and Stereochemical Analysis; Org. Lett. 2006, 8, 1037-1040. | |
555) | T. Frosch, M. Schmitt, K. Schenzel, J.H. Faber, G. Bringmann, W. Kiefer, J. Popp; In Vivo Localization and Identification of the Antiplasmodial Alkaloid Dioncophylline A in the Tropical Liana Triphyophyllum peltatum by a Combination of Fluorescence, Near Infrared Fourier Transform Raman Microscopy, and Density Functional Theory Calculations; Biopolymers 2006, 82, 295-300. | |
554) | S. Cîntǎ-Pînzaru, N. Peica, B. Küstner, S. Schlücker, M. Schmitt, T. Frosch, J.H. Faber, G. Bringmann, J. Popp; FT-Raman and NIR-SERS characterization of the antimalarial drugs chloroquine and mefloquine and their interaction with hematin; J. Raman Spectrosc. 2006, 37, 326-334.
| |
553) | G. Heubl, G. Bringmann, H. Meimberg; Molecular phylogeny and character evolution of carnivorous plant families in Caryophyllales - revisited; Plant Biol. 2006, 8, 821-830.
| |
552) | K. Felgentreff, C. Beisswenger, M. Griese, T. Gulder, G. Bringmann, R. Bals; The antimicrobial peptide cathelicidin interacts with airway mucus; Peptides 2006, 27, 3100-3106. | |
551) | B. Sontag, M. Rüth, P. Spiteller, N. Arnold, W. Steglich, M. Reichert, G. Bringmann; Chromogenic Meroterpenoids from the Mushrooms Russula ochroleuca and R. viscida; Eur. J. Org. Chem. 2006, 1023-1033. |
2005
550) | J. Mutanyatta, M. Bezabih, B.M. Abegaz, M. Dreyer, R. Brun, N. Kocher, G. Bringmann; The First 6'-O-Sulfated Phenylanthraquinones: Isolation from Bulbine frutescens, Structural Elucidation, Enantiomeric Purity, and Partial Synthesis; Tetrahedron 2005, 61, 8475-8484 (with cover picture). | |||||
549) | B. Clark, R.J. Capon, E. Lacey, S. Tennant, J.H. Gill, B. Bulheller, G. Bringmann; Gymnoascolides A-C: Aromatic Butenolides from an Australian Isolate of the Soil Ascomycete Gymnoascus reessii; J. Nat. Prod. 2005, 68, 1226-1230. | |||||
548) | O. Guhling, C. Kinzler, M. Dreyer, G. Bringmann, R. Jetter; Chemical composition of ant-plants: cuticular wax and glandular trichomes on leaves of Macaranga tanarius (Euphorbiaceae); J. Chem. Ecol. 2005, 31, 2323-2341. | |||||
547) | G. Bringmann, T.A.M. Gulder, K. Maksimenka, D. Kuckling, W. Tochtermann; A borderline case between meso and stable C1: an axially chiral, yet configurationally semi-stable biphenyl with two oppositely configured [10]paracyclophane portions; Tetrahedron 2005, 61, 7241-7246. | |||||
546) | G. Bringmann, G. Lang, K. Maksimenka, A. Hamm, T.A.M. Gulder, A. Dieter, A.T. Bull, J.E.M. Stach, N. Kocher, W.E.G. Müller, H.-P. Fiedler; Gephyromycin, the First Bridged Angucyclinone, from Streptomyces griseus Strain NTK 14; Phytochemistry 2005, 66, 1366-1373. | |||||
545) | E. Straube, W. Völkel, G. Bringmann, W. Dekant; Reaction of nitroso derivatives of dinitropyrenes with sulfhydryl groups of peptides and hemoglobin in vitro and in rats; Xenobiotica 2005, 35, 1147-1164. | |||||
544) | G. Bringmann, G. Lang, T.A.M. Gulder, H. Tsuruta, J. Mühlbacher, K. Maksimenka, S. Steffens, K. Schaumann, R. Stöhr, J. Wiese, J.F. Imhoff, S. Perovic-Ottstadt, O. Boreiko, W.E.G. Müller; The first sorbicillinoid alkaloids, the antileukemic sorbicillactones A and B, from a sponge-derived Penicillium chrysogenum strain; Tetrahedron 2005, 61, 7252-7265. | |||||
543) | A. Aiello, M. D’Esposito, E. Fattorusso, M. Menna, W.E.G. Müller, S. Perovic-Ottstadt, H. Tsuruta, T.A.M. Gulder, G. Bringmann; Daminin, a Bioactive Pyrrole Alkaloid from the Mediterranean Sponge Axinella damicornis; Tetrahedron 2005, 61, 7266-7270. | |||||
542) | F. Tribl, M. Gerlach, K. Marcus, E. Asan, T. Tatschner, T. Arzberger, H.E. Meyer, G. Bringmann, P. Riederer; “Subcellular Proteomics” of Neuromelanin Granules Isolated from the Human Brain; Mol. Cell. Proteomics 2005, 4, 945-957. | |||||
541) | G. Bringmann, M. Dreyer, H. Kopff, H. Rischer, M. Wohlfarth, H.A. Hadi, R. Brun, H. Meimberg, G. Heubl; ent-Dioncophylleine A and Related Dehydrogenated Naphthylisoquinoline Alkaloids, the First Asian Dioncophyllaceae-Type Alkaloids, from the “New” Plant Species Ancistrocladus benomensis; J. Nat. Prod. 2005, 68, 686-690. | |||||
540) | G. Bringmann, A.J. Price Mortimer, P.A. Keller, M.J. Gresser, J. Garner, M. Breuning; The Atroposelective Synthesis of Axially Chiral Biaryl Compounds; Angew. Chem. 2005, 117, 5518-5563; Angew. Chem. Int. Ed. 2005, 44, 5384-5427. | |||||
539) | J.M. Wanjohi, A. Yenesew, J.O. Midiwo, M. Heydenreich, M.G. Peter, M. Dreyer, M. Reichert, G. Bringmann; Three dimeric anthracene derivatives from the fruits of Bulbine abyssinica; Tetrahedron 2005, 61, 2667-2674. | |||||
538) | G. Bringmann, I. Kajahn, C. Neusüß, M. Pelzing, S. Laug, M. Unger, U. Holzgrabe; Analysis of the glucosinolate pattern of Arabidopsis thaliana seeds by capillary zone electrophoresis coupled to electrospray ionization-mass spectrometry; Electrophoresis 2005, 26, 1513-1522. | |||||
537) | M. Benitez, G. Bringmann, M. Dreyer, H. Garcia, H. Ihmels, M. Waidelich, K. Wissel; Design of a Chiral Mesoporous Silica and its Application as a Host for Stereoselective Di-п-methane Rearrangements; J. Org. Chem. 2005, 70, 2315-2321. | |||||
536) | H. Rischer, G. Heubl, H. Meimberg, M. Dreyer, H.A. Hadi, G. Bringmann; Ancistrocladus benomensis (Ancistrocladaceae): a new species from Peninsular Malaysia; Blumea 2005, 50, 357-365. | |||||
535) | T. Mülhaupt, H. Kaspar, S. Otto, M. Reichert, G. Bringmann, T. Lindel; Isolation, Structural Elucidation, and Synthesis of Curcutetraol; Eur. J. Org. Chem. 2005, 334-341. | |||||
534) | C. Loeffler, S. Berger, A. Guy, T. Durand, G. Bringmann, M. Dreyer, U. van Rad, J. Durner, M.J. Mueller; B1-Phytoprostanes trigger plant defense and detoxification responses; Plant Physiol. 2005, 137, 328-340. |
2004
533) | F. Bracher, W.J. Eisenreich, J. Mühlbacher, M. Dreyer, G. Bringmann; Saludimerines A and B, Novel-Type Dimeric Alkaloids with Stereogenic Centers and Configurationally Semistable Biaryl Axes; J. Org. Chem. 2004, 69, 8602-8608. | ||
532) | J.M. Scher, J. Zapp, H. Becker, N. Kather; J. Kolz, A. Speicher, M. Dreyer, K. Maksimenka, G. Bringmann; Optically active bisbibenzyls from Bazzania trilobata: isolation and stereochemical analysis by chromatographic, chiroptical, and computational methods; Tetrahedron 2004, 60, 9877-9881. | ||
531) | M. Müller, K. Lamottke, W. Steglich, S. Busemann, M. Reichert, G. Bringmann, P. Spiteller; Biosynthesis and Stereochemistry of Phlegmacin-Type Fungal Pigments; Eur. J. Org. Chem. 2004, 4850-4855. | ||
530) | A. Pérez, R. Ramírez-Durón, A. Piñeyro-López, N. Waksman, M. Reichert, G. Bringmann; The Absolute Configuration of Peroxisomicines A1 and A2; Tetrahedron 2004, 60, 8547-8552. | ||
529) | E. Sauer, M. Merdanovic, A. Price Mortimer, G. Bringmann, J. Reidl; PnuC and the Utilization of the Nicotinamide Riboside Analog 3-Aminopyridine in Haemophilus influenzae; Antimicrob. Agents Chemother. 2004, 48, 4532-4541. | ||
528) | G. Bringmann, D. Feineis, R. God, K. Maksimenka, J. Mühlbacher, K. Messer, M. Münchbach, K.-P. Gulden, E.-M. Peters, K. Peters; Resolution and chiroptical properties of the neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo) and related compounds: quantum chemical CD calculations and X-ray diffraction analysis; Tetrahedron 2004, 60, 8143-8151. | ||
527) | J. Hartung, R. Kneuer, C. Rummey, G. Bringmann; On the 6-endo Selectivity in 4-Penten-1-oxyl Radical Cyclizations; J. Am. Chem. Soc. 2004, 126, 12121-12129. | ||
526) | G. Bringmann, M. Dreyer, H. Rischer, K. Wolf, H.A. Hadi, R. Brun, H. Meimberg, G. Heubl; Ancistrobenomine A, the First Naphthylisoquinoline Oxygenated at Me-3, and Related 5,1’-Coupled Alkaloids, from the ‘New’ Plant Species Ancistrocladus benomensis; J. Nat. Prod. 2004, 67, 2058-2062. | ||
525)* | G. Bringmann, G. Lang, T. Gulder, K. Schaumann, S. Steffens, W.E.G. Müller, S. Perović, J.F. Imhoff; Sorbifuranone, Sorbivineton, Sorbivinetol und Derivate dieser Verbindungen; Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 10 2004 005 106.2), filed 02.02.04. | ||
524)* | G. Bringmann, G. Lang, K. Maksimenka, U. Hentschel, D. Stalke, N. Kocher, H.-P. Fiedler, A.T. Bull, S. Perović, W.E.G. Müller; O-Verbrückte Angucyclinone: Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 10 2004 004 906.8), filed 30.01.04. | ||
523)* | G. Bringmann, G. Lang, T. Gulder, K. Schaumann, W.E.G. Müller, S. Perović, R. Stöhr, J. Wiese, R. Schmaljohann, J.F. Imhoff; Verfahren zur Herstellung von Sorbicillacton A; German Patent Application (DE 102 004 004 901.7), filed 30.01.04. | ||
522) | R.S. Akundi, A. Macho, E. Munoz, K. Lieb, G. Bringmann, H.-W. Clement, M. Hüll, B.L. Fiebich; 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline-induced apoptosis in the human neuroblastoma cell line SK-N-SH; J. Neurochem. 2004, 91, 263-273. | ||
521)* | G. Bringmann, K. Maksimenka, T. Gulder, K. Schaumann, S. Perović, W.E.G. Müller, J. Hiort, R. Ebel, P. Proksch; Aspernigrin B und Aspernigrin-B-Derivate, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 102 004 002 884.2), filed 20.01.04. | ||
520) | G. Bringmann, J. Mühlbacher, M. Reichert, M. Dreyer, J. Kolz, A. Speicher; Stereochemistry of Isoplagiochin C, a Macrocyclic Bisbibenzyl from Liverworts; J. Am. Chem. Soc. 2004, 126, 9283-9290. | ||
519)* | G. Bringmann, G. Lang, H. Tsuruta, E. Fattorusso, A. Aiello, M. D’esposito, M. Menna, W.E.G. Müller, H.C. Schröder; S. Perović; Neue medizinisch einsetzbare Pyrrolalkaloide: Verfahren zu ihrer Isolierung, Synthese, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 102 004 002 885.0), filed 20.01.2004. | ||
518) | G. Bringmann, M. Dreyer, M. Michel, F. Tayman, R. Brun; Ancistroheynine B and two further 7,3’-coupled naphthylisoquinoline alkaloids from Ancistrocladus heyneanus; Phytochemistry 2004, 65, 2903-2907. | ||
517) | J. Hiort, K. Maksimenka, M. Reichert, S. Perović-Ottstadt, W.H. Lin, V. Wray, K. Steube, K. Schaumann, H. Weber, P. Proksch, R. Ebel, W.E.G. Müller, H. Weber; G. Bringmann; New Natural Products from the Sponge-Derived Fungus Aspergillus niger; J. Nat. Prod. 2004, 67, 1532-1543. | ||
516) | G. Bringmann, R.-M. Pfeifer, P. Schreiber, K. Hartner, N. Kocher, R. Brun, K. Peters, E.-M. Peters, M. Breuning; Synthesis and antitrypanosomal activity of 2-aminomethyl-1-(2-oxyphenyl)naphthalenes; Tetrahedron 2004, 60, 6335-6344. | ||
515) | G. Bringmann, M. Dreyer, J.H. Faber, P.W. Dalsgaard, D. Stærk, J.W. Jaroszewski, H. Ndangalasi, F. Mbago, R. Brun, S. Brøgger Christensen; Ancistrotanzanine C and Related 5,1’- and 7,3’-Coupled Naphthylisoquinoline Alkaloids from Ancistrocladus tanzaniensis; J. Nat. Prod. 2004, 67, 743-748. | ||
514) | G. Bringmann, Y. Reichert, V.V. Kane; The total synthesis of streptonigrin and related antitumor antibiotic natural products; Tetrahedron 2004, 60, 3539-3574. | ||
513) | G. Bringmann, G. Lang, M. Michel, M. Heubes; Stereochemical assignment of the fungal metabolite xestodecalactone A by total synthesis; Tetrahedron Lett. 2004, 45, 2829-2831. | ||
512) | W.E.G. Müller, N.J. Thakur, A.N. Thakur, H. Ushijima, A. Krasko, G. Le Pennec, M.M. Indap, , S. Perović-Ottstadt, H.C. Schröder, G. Lang, G. Bringmann; Matrix-mediated canal formation in primmorphs from the sponge Suberites domuncula involves the expression of a CD36 receptor-ligand system; J. Cell Science 2004, 117, 2579-2590. | ||
511) | G. Bringmann, G. Lang, S. Steffens, K. Schaumann; Petrosifungins A and B, Novel Cyclodepsipeptides from a Sponge-Derived Strain of Penicillium brevicompactum; J. Nat. Prod. 2004, 67, 311-315. | ||
510) | M. Unger, M. Dreyer, S. Specker, S. Laug, M. Pelzing, C. Neusüß, U. Holzgrabe, G. Bringmann; Analytical Characterisation of Crude Extracts from an African Ancistrocladus Species Using High-Performance Liquid Chromatography and Capillary Electrophoresis Coupled to Ion Trap Mass Spectrometry; Phytochem. Anal. 2004, 15, 21-26. | ||
509) | G. Bringmann, R.-M. Pfeifer, P. Schreiber, K. Hartner, M. Schraut, M. Breuning; The ‘lactone method’: enantioselective preparation of novel P,N-biaryl ligands and their use in the synthesis of the biarylic alkaloids, ancistrotanzanine B and ancistroealaine A; Tetrahedron 2004, 60, 4349-4360. | ||
508) | G. Bringmann, R.-M. Pfeifer, M. Breuning, M. Reichert, K. Messer, M. Schraut, G. Tóth; Structure of trans-Isoshinanolone in the Crystal and in Solution; Z. Naturforsch. 2004, 59b, 100-105. |
2003
507) | G. Bringmann, R.-M. Pfeifer, C. Rummey, K. Hartner, M. Breuning; Synthesis of Enantiopure Axially Chiral C3-Symmetric Tripodal Ligands and Their Application as Catalysts in the Asymmetric Addition of Dialkylzinc to Aldehydes; J. Org. Chem. 2003, 68, 6859-6863. | ||
506) | G. Bringmann, A. Hamm, M. Schraut; Atroposelective Biaryl Coupling with Chiral Catalysts: Total Synthesis of the Antileishmanial Naphthylisoquinoline Alkaloids Ancistrotanzanine B and Ancistroealaine A; Org. Lett. 2003, 5, 2805-2808. | ||
505)* | W.E.G. Müller, N.J. Thakur, A.N. Thakur, H.C. Schröder, G. Lang, H. Tsuruta, G. Bringmann; 2-Methylthio-1,4-naphthochinon und 2-Methylthio-1,4-naphthochinon-Derivate, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 103 437 98.3), filed 22.09.2003. | ||
504) | W. Tochtermann, D. Kuckling, C. Meints, J. Kraus, G. Bringmann; Bridged bioxepines and bi[10]paracyclophanes - synthesis and absolute configuration of a bi[10]paracyclophane with two chiral planes and one chiral axis; Tetrahedron 2003, 59, 7791-7801. | ||
503) | A. Dieter, A. Hamm, H.-P. Fiedler, M. Goodfellow, W.E.G. Müller, R. Brun, W. Beil, G. Bringmann; Pyrocoll, an antibiotic, antiparasitic, and antitumor compound produced by a novel alkalophilic Streptomyces strain; J. Antibiot. 2003, 56, 639-646. | ||
502) | G. Bringmann, M. Breuning, R.-M. Pfeifer, C. P. Schreiber; Atropo-Enantioselective Synthesis of a C3-Symmetric Tripodal Ligand with Three Axially Chiral Biaryl Subunits; Tetrahedron: Asymmetry 2003, 14, 2225-2228. | ||
501)* | G. Bringmann, U. Hentschel, W. Ziebuhr, S. Kozitskaya, G. Lang, K. Schaumann, S. Steffens, W.E.G. Müller; Tajixanthonhydrat und Tajixanthonhydrat-Derivate, deren biologische Aktivitaeten und deren Verwendung; German Patent Application (DE 103 29 874.6), filed 02.07.2003. | ||
500) | G. Bringmann, M. Dreyer, J.H. Faber, P.W. Dalsgaard, D. Stærk, J. Jaroszewski, H. Ndangalasi, F. Mbago, R. Brun, M. Reichert, K. Maksimenka, S. Brøgger Christensen; Ancistrotanzanine A, the First 5,3’-Coupled Naphthylisoquinoline Alkaloid, and Two Further, 5,8’-Linked Related Compounds from the Newly Described Plant Species Ancistrocladus tanzaniensis; J. Nat. Prod. 2003, 66, 1159-1165. | ||
499) | N. Stiefl, G. Bringmann, C. Rummey, K. Baumann; Evaluation of extended parameter sets for the 3D-QSAR technique MaP: Implications for interpretability and model quality exemplified by antimalarially active naphthylisoquinoline alkaloids; J. Comput.-Aided Mol. Des. 2003, 17, 347-365. | ||
498) | G. Bringmann, C. Schneider, U. Möhler, R.-M. Pfeifer, R. Götz, L. Aké Assi, E.-M. Peters, K. Peters; Two Atropisomeric N-Methyldioncophyllines A and N-Methylphylline, their Naphthalene-Free Heterocyclic Moiety, from Ancistrocladus barteri; Z. Naturforsch. 2003, 58b, 577-584. | ||
497) | K. Peters, E.-M. Peters, A. Wuzik, R.-M. Pfeifer, G. Bringmann; Crystal structure of 3’-benzyloxy-2’-naphthyl-1-bromo-2-naphthoate, C28H19BrO3; Z. Kristallogr. NCS. 2003, 218, 209-210. | ||
496) | K. Kamikawa, K. Norimura, M. Furusyo, T. Uno, Y. Sato, A. Konoo, G. Bringmann, M. Uemura; Planar Chiral (h-6-Arene) Ruthenium Cp Complexes in Organic Synthesis: Diastereoselective Complexation of Arene Compounds with Benzylic Alcohol and Its Synthetic Application to Chiral Biaryls; Organometallics 2003, 22, 1038-1046. | ||
495)* | G. Bringmann, C. Rummey, S. Neumann, R. Brun, A. Stich, V. Hörr, W.E.G. Müller; Medizinisch nützliche 3,3-Dimethyl-8-oxoisochinoline und deren Derivate; Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 103 03 254.1-44); filed 28.01.2003; PCT/EP03/14849. | ||
494) | G. Bringmann, G. Lang, S. Steffens, E. Günther, K. Schaumann; Evariquinone, isoemericellin, and stromemycin from a sponge derived strain of the fungus Emericella variecolor; Phytochemistry 2003, 63, 437-443. | ||
493) | G. Bringmann, R.-M. Pfeifer, C. Rummey, T. Pabst, D. Leusser, D. Stalke; Structural Investigation of a Configurationally Stable Seven-Membered Bridged Biaryl of Relevance for Atroposelective Biaryl Synthesis; Z. Naturforsch. 2003, 58b, 231-236. | ||
492) | G. Bringmann, C. Rummey; 3D-QSAR Investigations on Antimalarial Naphthylisoquinoline Alkaloids, by Comparative Molecular Similarity Indices Analysis (CoMSIA), Based on Different Alignment Approaches; J. Chem. Inf. Comput. Sci. 2003, 43, 304-316. | ||
491) | G. Bringmann, U. Holzgrabe, V. Hoerr, A. Stich; Antitrypanosomal naphthylisoquinoline alkaloids and related compounds; Pharmazie 2003, 58, 343-346. | ||
490) | G. Bringmann; From tropical lianas to novel antiplasmodial agents: The naphthylisoquinoline alkaloids; in Drugs against parasitic diseases: R&D methodologies and issues (Eds. A.H. Fairlamb, R.G. Ridley, H.J. Vial), World Health Organisation, Geneva, 2003, 145-152. | ||
489) | G. Bringmann, W. Saeb, M. Rückert, J. Mies, M. Michel, V. Mudogo, R. Brun; Ancistrolikokine D, a 5,8’-coupled naphthylisoquinoline alkaloid, and related natural products from Ancistrocladus likoko; Phytochemistry 2003, 62, 631-636. | ||
488)* | G. Bringmann, R.-M. Pfeifer, R. Brun, W.E.G. Müller; Medizinisch nützliche 1-Phenyl-2-aminomethylnaphthaline, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 103 01 650.3); filed 17.01.2003; issued 05.08 2004; PCT/EP03/14848. | ||
487) | G. Bringmann, K.-P. Gulden, S. Busemann; Calculation of circular dichroism spectra of michellamines A and C, based on a complete conformational analysis; Tetrahedron 2003, 59, 1245-1253. | ||
486) | G. Bringmann, G. Lang, J. Mühlbacher, K. Schaumann, S. Steffens, P.G. Rytik, U. Hentschel, J. Morschhäuser, W.E.G. Müller; Sorbicillactone A, a Strucurally Unprecedented Bioactive Novel-Type Alkaloid from a Sponge-Derived Fungus; in Marine Mol. Biol. (Ed. W.E.G. Müller), Springer Verlag, Berlin, 2003, pp. 231-253. | ||
485) | G. Bringmann, G. Lang; Full Absolute Stereostructures of Natural Products Directly From Crude Extracts: the HPLC-MS/MS-NMR-CD ‘Triad’; in Marine Mol. Biol. (Ed. W.E.G. Müller), Springer Verlag, Berlin, 2003, pp. 89-116. | ||
484)* | G. Bringmann, G. Lang, J. Mühlbacher, K. Schaumann, S. Steffens, W.E.G. Müller; Sorbicillacton A und Sorbicillacton-A-Derivate; Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung; German Patent Application (DE 102 38 257.3), filed 21.08.02; PCT/EP03/07805. Issued 11.03.2004. | ||
483) | G. Bringmann, K. Messer, B. Schwöbel, R. Brun, L. Aké Assi; Habropetaline A, an Antimalarial Naphthylisoquinoline Alkaloid from Triphyophyllum peltatum; Phytochemistry 2003, 62, 345-349. | ||
482) | G. Bringmann, J. Mühlbacher, K. Messer, M. Dreyer, R. Ebel, B.W. Nugroho, V. Wray, P. Proksch; Cyclorocaglamide, the First Bridged Cyclopentatetrahydrobenzofuran, and a Related “Open Chain” Rocaglamide Derivative from Aglaia oligophylla; J. Nat. Prod. 2003, 66, 80-85. | ||
481) | C.T. Pabel, J. Vater, C. Wilde, P. Franke, J. Hofmeister, B. Adler, G. Bringmann, J. Hacker, U. Hentschel; Antimicrobial activities and matrix-assisted laser desorption/ionization mass spectrometry of Bacillus isolates from the marine sponge Aplysina aerophoba; Mar. Biotechnol. 2003, 5, 424-434. |
2002
480) | G. Bringmann, S. Tasler, R.-M. Pfeifer, M. Breuning; The directed synthesis of axially chiral ligands, reagents, catalysts, and natural products: through the lactone methodology; J. Organomet. Chem. 2002, 661, 49-65. | |||
479) | G. Bringmann, M. Breuning, R.-M. Pfeifer, W.A. Schenk, K. Kamikawa, M. Uemura; The lactone concept: - a novel approach to the metal-assisted atroposelective construction of axially chiral biaryl systems; J. Organomet. Chem. 2002, 661, 31-47. | |||
478) | G. Bringmann, D. Menche, J. Mühlbacher, M. Reichert, N. Saito, S. Pfeiffer, B.H. Lipshutz; On the Verge of Axial Chirality: Atroposelective Synthesis of the AB-Biaryl Fragment of Vancomycin; Org. Lett. 2002, 4, 2833-2836. | |||
477) | R.A. Edrada, M. Heubes, G. Brauers, V. Wray, A. Berg, U. Gräfe, M. Wohlfarth, J. Mühlbacher, K. Schaumann, Sudarsono, G. Bringmann, P. Proksch; Online Analysis of Xestodecalactones A-C, Novel Bioactive Metabolites from the Fungus Penicillium cf. montanense and Their Subsequent Isolation from the Sponge Xestospongia exigua; J. Nat. Prod. 2002, 65, 1598-1604. | |||
476) | G. Bringmann, T. Noll, H. Rischer; In vitro germination and establishment of tissue cultures of Bulbine caulescens and of two Kniphofia species (Asphodelaceae); Plant Cell Rep. 2002, 21, 125-129. | |||
475) | B.M. Abegaz, M. Bezabih, T. Msuta, R. Brun, D. Menche, J. Mühlbacher, G. Bringmann; Gaboroquinones A and B, and 4’-O-Demethylknipholone-4’-O-ß- d-glucopyranoside, Phenylanthraquinones from the Roots of Bulbine frutescens; J. Nat. Prod. 2002, 65, 1117-1121. | |||
474) | G. Bringmann, M. Wohlfarth, H. Rischer, J. Schlauer, R. Brun; Extract Screening by HPLC Coupled to MS-MS, NMR, and CD: A dimeric and three monomeric naphthylisoquinoline alkaloids from Ancistrocladus griffithii; Phytochemistry 2002, 61, 195-204. | |||
473) | G. Bringmann, K. Messer, R. Brun, V. Mudogo; Ancistrocongolines A-D, New Naphthylisoquinoline Alkaloids from Ancistrocladus congolensis; J. Nat. Prod. 2002, 65, 1096-1101. | |||
472) | G. Bringmann, D. Menche, J. Kraus, J. Mühlbacher, K. Peters, E.-M. Peters, R. Brun, M. Bezabih, B.M. Abegaz; Atropo-Enantioselective Total Synthesis of Knipholone and Related Antiplasmodial Phenylanthraquinones; J. Org. Chem. 2002, 67, 5595-5610. | |||
471) | G. Bringmann, D. Feineis, R. God, K. Peters, E.-M. Peters, J. Scholz, F. Riederer, A. Moser; 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo) and Related Derivatives: Chemistry and Biochemical Effects on Catecholamine Biosynthesis; Bioorg. Med. Chem. 2002, 10, 2207-2214. | |||
470) | S. Tasler, G. Bringmann; Biarylic Biscarbazole Alkaloids: Occurrence, Stereochemistry, Synthesis, and Bioactivity; Chem. Record 2002, 2, 114-127. | |||
469) | M. Meyring, J. Mühlbacher, K. Messer, N. Kastner-Pustet, G. Bringmann, A. Mannschreck, G. Blaschke; In vitro biotransformation of (R) and (S)-thalidomide: Application of circular dichroism spectroscopy to the stereochemical characterization of the hydroxylated metabolites; Anal. Chem. 2002, 74, 3726-3735. | |||
468) | P. Riederer, P. Foley, G. Bringmann, D. Feineis, R. Brückner, M. Gerlach; Biochemical and pharmacological characterization of TaClo: a biologically relevant neurotoxin?; Eur. J. Pharmacol. 2002, 442, 1-16. | |||
467) | F. Riederer, A. Luborzewski, R. God, G. Bringmann, J. Scholz, D. Feineis, A. Moser; Modification of tyrosine hydroxylase activity by chloral derived ß-carbolines in vitro; J. Neurochem. 2002, 81, 814-819. | |||
466) | G. Bringmann, K. Messer, K. Wolf, J. Mühlbacher, M. Grüne, R. Brun, A.M. Louis; Dioncophylline E from Dioncophyllum tholonnii, the first 7,3’-coupled Dioncophyllaceous naphthylisoquinoline alkaloid; Phytochemistry 2002, 60, 389-397. | |||
465) | G. Bringmann, M. Münchbach, D. Feineis, K. Messer, S. Diem, M. Herderich, H.-W. Clement, C. Stichel-Gunkel, W. Kuhn; “Chiral” and “achiral” determination of the neurotoxin TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline) from blood and urine samples by high-performance liquid chromatography - electrospray ionization tandem mass spectrometry; J. Chromatogr. B 2002, 767, 321-332. | |||
464) | H. Rischer, A. Hamm, G. Bringmann; Nepenthes insignis uses a C2-portion of the carbon skeleton of L-alanine acquired via its carnivorous organs, to build up the allelochemical plumbagin; Phytochemistry 2002, 59, 603-609. | |||
463) | G. Bringmann, D. Menche, R. Brun, T. Msuta, B.M. Abegaz; Bulbine-Knipholone, a New Axially Chiral Phenylanthraquinone from Bulbine abyssinica (Asphodelaceae): Isolation, Structural Elucidation, Synthesis, and Antiplasmodial Activity; Eur. J. Org. Chem. 2002, 1107-1111. | |||
462) | G. Bringmann, J. Hinrichs, P. Henschel, J. Kraus, K. Peters, E.-M. Peters; Atropo-Enantioselective Synthesis of the Natural Bicoumarin (+)-Isokotanin A via a Configurationally Stable Biaryl Lactone; Eur. J. Org. Chem. 2002, 1096-1106. | |||
461) | G. Bringmann, H. Rischer, J. Schlauer, K. Wolf, A. Kreiner, M. Duschek, L. Aké Assi; The Tropical Liana Triphyophyllum peltatum (Dioncophyllaceae): Formation of Carnivorous Organs is Only a Facultative Prerequisite for Shoot Elongation; Carniv. Pl. Newslett. 2002, 31, 44-52. | |||
460) | G. Bringmann, M. Breuning, P. Henschel, J. Hinrichs; Asymmetric Synthesis of (M)-2-Hydroxymethyl-1(2-Hydroxy-4,6-dimethylphenyl)naphthalene via a Configurationally Unstable Biaryl Lactone; Org. Syntheses 2002, 79, 72-83. | |||
459) | A. Schultz, S. Laschat, M. Morr, S. Diele, M. Dreyer, G. Bringmann; Highly Branched Alkanoic Acids from the Preen-Gland Wax of the Domestic Goose as Building Blocks for Chiral Triphenylens; Helv. Chim. Acta 2002, 85, 3909-3918. | |||
458)* | G. Bringmann, P. Proksch, M. Heubes, R.A. Edrada, J.K. Sudarsono, E. Günther (Zentaris AG); Neue Decalactone aus assoziierten Pilzen mariner Schwämme und deren synthetische Derivate als Arzneimittel. - Novel Decalactones from Associated Fungi of Marine Sponges and their Synthetic Derivatives as Medicaments; International Patent Application (PCT/EP 02/04676); Filed: 09.05.2001. International Publication Number: WO 02/092589 A2. Issued 21.11.2002. |
2001
457) | K. Kamikawa, M. Furusyo, T. Uno, Y. Sato, A. Konoo, G. Bringmann, M. Uemura; Diastereoselective Ruthenium-Cp Complexation of Enantiopure Arene Compounds Possessing Stereogenic Benzylic Alcohol Functions; Org. Lett. 2001, 3, 3667-3670. | |||||
456) | G. Bringmann, D. Feineis; Stress-Related Polyketide Metabolism in Ancistrocladaceae and Dioncophyllaceae; J. Exp. Bot. 2001, 52, 2015-2022. | |||||
455) | G. Bringmann, D. Menche; Stereoselective Total Synthesis of Axially Chiral Natural Products via Biaryl Lactones; Acc. Chem. Res.2001, 34, 615-624. | |||||
454) | G. Bringmann, H. Rischer; In vitro propagation of the alkaloid-producing, rare African liana Triphyophyllum peltatum (Dioncophyllaceae); Plant Cell Rep. 2001, 20, 591-595. | |||||
453) | G. Bringmann, K. Wolf, M. Meininger, M. Rokitta, A. Haase; In vivo 19F NMR Chemical Shift Imaging of Ancistrocladaceae; Protoplasma 2001, 218, 134-143. | |||||
452) | H. Ihmels, K. Faulhaber, C. Sturm, G. Bringmann, K. Messer, N. Gabellini, D. Vedaldi, G. Viola; Acridizinium Salts as a Novel Class of DNA-Binding and Site-Selective DNA-Photodamaging Chromophores; Photochem. Photobiol. 2001, 74, 505-511. | |||||
451) | G. Bringmann, J. Schlauer, H. Rischer, M. Wohlfarth, R. Haller, S. Bär, R. Brun; Antidesmone, a novel antitrypanosomal alkaloid; Pharm. Pharmacol. Lett. 2001, 11, 47-48. | |||||
450) | G. Bringmann, M. Wohlfarth; H. Rischer, M. Heubes, W. Saeb, S. Diem, M. Herderich, J. Schlauer; A Photometric Screening Method for Dimeric Naphthylisoquinoline Alkaloids and Complete On-Line Structural Elucidation of a Dimer in Crude Plant Extracts, by the LC-MS/LC-NMR/LC-CD Triad; Anal. Chem. 2001, 73, 2571-2577. | |||||
449) | G. Bringmann, A. Wuzik, O. Schupp, J. Kümmel, W.A. Schenk; Atropo-enantioselective ring cleavage of Lewis acid modified biaryl thionolactones; Organometallics 2001, 20, 1692-1694. | |||||
448) | G. Bringmann, M. Münchbach, D. Feineis, K. Faulhaber, H. Ihmels; Studies on single-strand scissions to cell-free plasmid DNA by the dopaminergic neurotoxin ‘TaClo’ (1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline); Neurosci. Lett. 2001, 304, 41-44. | |||||
447) | G. Bringmann, S. Tasler; Synthesis of Methylene-Bridged Binary Carbazole Alkaloids and a Related Tricarbazole; Tetrahedron 2001, 57, 2337-2343. | |||||
446) | G. Bringmann, T. Pabst, P. Henschel, M. Michel; First total synthesis of the mastigophorenes C and D and of simplified unnatural analogs; Tetrahedron 2001, 57, 1269-1275. | |||||
445) | G. Bringmann, D. Menche; First, Atropo-enantioselective Total Synthesis of the Axially Chiral Phenylanthraquinone Natural Products Knipholone and 6’-O-Methylknipholone; Angew. Chem. 2001, 113, 1733-1736; Angew. Chem. Int. Ed. 2001, 40, 1687-1690. | |||||
444) | G. Bringmann, A. Hamm, J. Kraus, M. Ochse, A. Noureldeen, D. Jumbam; Gardenamide A from Rothmannia urcelliformis (Rubiaceae) - Isolation, Absolute Stereostructure, and Biomimetic Synthesis from Genipine; Eur. J. Org. Chem. 2001, 1983-1987. | |||||
443) | G. Bringmann, C. Günther, P. Henschel, K. Peters, E.-M. Peters; First Total Synthesis of the 7,6’-Coupled Antifungal Naphthylisoquinoline Alkaloid Dioncophylline B; Tetrahedron 2001, 57, 1253-1259. | |||||
442) | H. Ihmels, K. Faulhaber, K. Wissel, G. Bringmann, K. Messer, G. Viola, D. Vedaldi; Synthesis and Investigation of the DNA-Binding and DNA-Photodamaging Properties of Indolo[2,3-b]-Quinolizinium Bromide; Eur. J. Org. Chem. 2001, 1157-1161. | |||||
441) | G. Bringmann, S. Tasler, H. Endress, J. Mühlbacher; En route to the first stereoselective synthesis of axially chiral biscarbazole alkaloids; J. Chem. Soc., Chem. Commun. 2001, 761-762. | |||||
440) | G. Bringmann, S. Tasler, H. Endress, J. Kraus, K. Messer, M. Wohlfarth, W. Lobin; Murrastifoline-F: First Total Synthesis, Atropo-Enantiomer Resolution, and Stereoanalysis of an Axially Chiral N,C-Coupled Biaryl Alkaloid; J. Am. Chem. Soc. 2001, 123, 2703-2711. | |||||
439) | G. Bringmann, J. Hinrichs, K. Peters, E.-M. Peters; Synthesis of a Chiral Aryl-Ferrocenyl Ligand, by Intramolecular Coupling to a Biaryl-Related Lactone; J. Org. Chem.2001, 66, 629-632. | |||||
438) | G. Bringmann, J. Mühlbacher, C. Repges, J. Fleischhauer; MD-Based CD Calculations on the Absolute Axial Configuration of the Naphthylisoquinoline Alkaloid Dioncophylline A; J. Comp. Chem. 2001, 22, 1273-1278. | |||||
437) | E.-M. Peters, K. Peters, G. Bringmann; Crystal structure of (1R,3R)-8-benzyloxy-N-benzyl-6-hydroxy-1,3-dimethyltetrahydroisoquinoline hydrobromide, (C9H6N)(CH3)2(CH2C6H5)(OH)(OCH2C6H5).HBr; Z. Kristallogr. NCS 2001, 216, 223-224. | |||||
436) | G. Bringmann, S. Tasler; Oxidative Aryl Coupling Reactions: A Biomimetic Approach to Configurationally Unstable or Axially Chiral Biaryl Natural Products and Related Bioactive Compounds; Tetrahedron 2001, 57, 331-343. | |||||
435) | G. Bringmann, C. Günther, M. Ochse, O. Schupp, S. Tasler; Axially Chiral Biaryls, a Multi-Facetted Class of Stereochemically, Biosynthetically, and Pharmacologically Intriguing Secondary Metabolites; in Progr. Chem. Org. Nat. Prod., Vol. 82 (Eds.: W. Herz, H. Falk, G.W. Kirby, R.E. Moore, C. Tamm) Wien, 2001, pp. 1-249. | |||||
434) | B. Chimanuka, G. François, G. Timperman, Y. Vanden Heyden, J. Holenz, J. Plaizier-Vercammen, G. Bringmann; A comparison of the stage-specific efficacy of chloroquine, artemether, and dioncophylline B, against the rodent malaria parasite Plasmodium chabaudi chabaudi in vivo; Parasitol. Res. 2001, 87, 795-803. | |||||
433) | M. Dreyer, B.W. Nugroho, F.I. Bohnenstengel, R. Ebel, V. Wray, L. Witte, G. Bringmann, J. Mühlbacher, M. Herold, P.D. Hung, L.C. Kiet, P. Proksch; New Insecticidal Rocaglamide Derivatives and Related Compounds from Aglaia oligophylla; J. Nat. Prod. 2001, 64, 415-420. | |||||
432) | E.-M. Peters, K. Peters, J. Hinrichs, G. Bringmann; Crystal structure of N,N-Diisopropyl 2-iodoferrocenecarboxamide, (C5H5)Fe(C5H3I)(C7H14NO); Z. Kristallogr. NCS 2001, 216, 221-222. | |||||
431) | G. Bringmann, M. Wenzel, H.P. Bringmann, J. Schlauer, L. Aké Assi, F. Haas; Uptake of the amino acid alanine by digestive leaves: proof of carnivory of the tropical liana Triphyophyllum peltatum (Dioncophyllaceae); Carniv. Pl. Newslett. 2001, 30, 15-21. | |||||
430) | R. Feling, K. Polborn, W. Steglich, J. Mühlbacher, G. Bringmann; The absolute configuration of the mushroom metabolites involutin and chamonixin; Tetrahedron 2001, 57, 7857-7863. | |||||
429) | S. Tasler, H. Endress, G. Bringmann; Synthesis of 2,2’-Biscarbazoles by Reductive Biaryl Coupling; Synthesis 2001, 1993-2002. | |||||
428) | E.-M. Peters, K. Peters, S. Tasler, H. Endress, G. Bringmann; Crystal structure of Ethyl 1-Methoxy-9-methyl-9H-carbazol-3-carboxylate, C12H6(OCH3)(CH3)CO2(C2H5); Z. Kristallogr. NCS. 2001, 216, 119-120. | |||||
427) | G. Bringmann, K. Messer, W. Saeb, E.-M. Peters, K. Peters; The absolute configuration of (+)-isoshinanolone and in situ LC-CD analysis of its stereoisomers from crude extracts; Phytochemistry 2001, 56, 387-391. | |||||
426) | G. Bringmann, J. Hinrichs, T. Pabst, P. Henschel, K. Peters, E.-M. Peters; From Dynamic to Non-Dynamic Kinetic Resolution of Lactone-Bridged Biaryls: Synthesis of Mastigophorene B; Synthesis 2001, 155-167. |
2000
425) | G. Bringmann, M. Wohlfarth, M. Heubes; Observation of exchangeable protons by high-performance liquid chromatography-nuclear magnetic resonance spectroscopy and -electrospray ionization mass spectrometry: a useful tool for the hyphenated analysis of natural products; J. Chromatogr. A 2000, 904, 243-249. | |||||
424) | G. Bringmann, W. Saeb, J. Mies, K. Messer, M. Wohlfarth, R. Brun; One-Step Oxidative Dimerization of Genuine, Unprotected Naphthylisoquinoline Alkaloids to Give Michellamines and Other Bioactive Quateraryls; Synthesis 2000, 1843-1847. | |||||
423) | G. Bringmann, T. Pabst, P. Henschel, J. Kraus, K. Peters, E.-M. Peters, D.S. Rycroft, J. Connolly; Non-Dynamic and Dynamic Kinetic Resolution of Lactones with Stereogenic Centers and Axes: Stereoselective Total Synthesis of Herbertenediol and Mastigophorenes A and B; J. Am. Chem. Soc. 2000, 122, 9127-9133. | |||||
422) | K.L. Double, L. Zecca, P. Costi, M. Mauer, C. Griesinger, S. Ito, D. Ben-Shachar, G. Bringmann, R.G. Fariello, P. Riederer, M. Gerlach; Structural characteristics of human neuromelanin and synthetic dopamine melanins; J. Neurochem. 2000, 75, 2583-2589. | |||||
421) | G. Bringmann, A. Hamm, C. Günther, M. Michel, R. Brun, V. Mudogo; Ancistroealaines A and B, Two New Bioactive Naphthylisoquinolines, and Related Naphthoic Acids from Ancistrocladus ealaensis; J. Nat. Prod. 2000, 63, 1465-1470. | |||||
420) | G. Bringmann, H. Rischer, M. Wohlfarth, J. Schlauer; Biosynthesis of Antidesmone in Cell Cultures of Antidesma membranaceum (Euphorbiaceae): An Unprecedented Class of Glycine-Derived Alkaloids; J. Am. Chem. Soc. 2000, 122, 9905-9910. | |||||
419) | G. Bringmann, C. Günther, W. Saeb, J. Mies, A. Wickramasinghe, V. Mudogo, R. Brun; Ancistrolikokines A - C: New 5,8’-Coupled Naphthylisoquinoline Alkaloids from Ancistrocladus likoko; J. Nat. Prod. 2000, 63, 1333-1337. | |||||
418) | K. Wolf, A. van der Toorn, K. Hartmann, L. Schreiber, W. Schwab, A. Haase, G. Bringmann; Metabolite monitoring in plants with double-quantum filtered chemical shift imaging; J. Exp. Bot. 2000, 51, 2109-2117. | |||||
417) | G. Bringmann, W. Saeb, K. Messer, M. Wohlfarth, R. Brun; Jozipeltine A, a Novel, Unnatural Dimer of the Highly Hydroxylated Naphthylisoquinoline Alkaloid Dioncopeltine A; Tetrahedron 2000, 56, 5871-5875. | |||||
416) | G. Bringmann, J. Kraus, U. Schmitt, C. Puder, A. Zeeck; The Absolute Configuration of g-Rubromycin and Related Spiro Compounds, by Quantum Chemical CD Calculations; Eur. J. Org. Chem. 2000, 2729-2734. | |||||
415) | G. Bringmann, J. Schlauer, H. Rischer, M. Wohlfarth, J. Mühlbacher, A. Buske, A. Porzel, J. Schmidt, G. Adam; Revised Structure of Antidesmone, an Unusual Alkaloid from Tropical Antidesma Plants (Euphorbiaceae); Tetrahedron 2000, 56, 3691-3695. | |||||
414) | G. Bringmann, D. Feineis, R. God, R. Brückner, J.-A. Protzen, M. Blank, K. Peters, E.-M. Peters, B. Janetzky, H. Reichmann; Chemical Modification of the Mitochondrial Complex I Inhibitor 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline: Synthesis and Evaluation of N-Alkanoyl Derivatives; Z. Naturforsch. 2000, 55c, 620-630. | |||||
413) | G. Bringmann, J. Hinrichs, P. Henschel, K. Peters, E.-M. Peters; Synthesis of Constitutionally Unsymmetric 7-Membered Biaryl Lactones by Ni-Mediated Intramolecular Coupling; Synlett 2000, 1822-1824. | |||||
412) | P. Sand, D. Kavvadias, D. Feineis, P. Riederer, P. Schreier, M. Kleinschmitz, F.-C. Czygan, A. Abou-Mandour, G. Bringmann, H. Beckmann; Naturally occurring benzodiazepines: current status of research and clinical implications; Eur. Arch. Psychiatry Clin. Neurosci. 2000, 250, 194-202. | |||||
411) | K. Peters, E.-M. Peters, T. Pabst, G. Bringmann; Crystal structure of 3,8-Di-tert.-butyl-4-methoxy-1-methyl-9,10-(diphenylmethylidenedioxy)dibenzo[b,d]pyran-6-one, C6H[O2C(C6H5) 2](C4H9)COO(C6H)(CH3)(OCH3)(C4H9); Z. Kristallogr. NCS 2000, 215, 603-604. | |||||
410) | G. Bringmann, C. Günther, W. Saeb, J. Mies, R. Brun, L. Aké Assi; 8-O-Methyldionco-phyllinol B and revised structures of other 7,6’-coupled naphthylisoquinoline alkaloids from Triphyphyllum peltatum (Dioncophyllaceae); Phytochemistry 2000, 54, 337-346. | |||||
409) | G. Bringmann, W. Saeb, J. Kraus, R. Brun, G. François; Jozimine B, a Constitutionally Unsymmetric, Antiplasmodial ‘Dimer’ of the Naphthylisoquinoline Alkaloid Ancistrocladine; Tetrahedron 2000, 56, 3523-3531. | |||||
408) | G. Bringmann, R. Brückner, D. Feineis, E.-M. Peters, K. Peters; 2-Hexanoyl-1-tribromo-methyl-1,2,3,4-tetrahydro-ß-carboline: Crystal Structure Analysis of a Potent Inhibitor of Complex I of Mitochondrial Respiration; Z. Naturforsch. 2000, 55b, 94-99. | |||||
407) | H. Meimberg, P. Dittrich, G. Bringmann, J. Schlauer, G. Heubl; Molecular Phylogeny of Caryophyllidae s.l. based on matK sequences with special emphasis on carnivorous taxa; Plant Biol. 2000, 2, 218-228. | |||||
406) | G. Gille, T. Pabst, B. Janetzky, G. Bringmann, H. Reichmann, W.-D. Rausch; Neurotrophic effects of simplified mastigophorene analogs on mesencephalic dopaminergic cells in primary culture; Drug. Dev. Res. 2000, 50, 153-156. | |||||
405) | K. Peters, E.-M. Peters, M. Welter, G. Bringmann; Crystal structure of 1-(3’,5’-dimethoxy-phenyl)-2-methyloximinopropanol, C6H3(OCH3)2CH(OH)C(NOCH3)(CH3); Z. Kristallogr. NCS 2000, 215, 405-406. | |||||
404) | G. Bringmann, D. Feineis, R. Brückner, M. Blank, K. Peters, E.-M. Peters, H. Reichmann, B. Janetzky, C. Grote, H.-W. Clement, W. Wesemann; Bromal-Derived Tetrahydro-ß-carbolines as Neurotoxic Agents: Chemistry, Impairment of the Dopamine Metabolism, and Inhibitory Effects on Mitochondrial Respiration; Bioorg. Med. Chem. 2000, 8, 1467-1478. | |||||
403) | R. Cseh, M. Hetzer, K. Wolf, J. Kraus, G. Bringmann, R. Benz; Interaction of Phloretin with Membranes: On the Mode of Action of Phloretin at the Water-Lipid Interface; Eur. Biophys. J. 2000, 29, 172-183. | |||||
402) | G. Bringmann, J. Hinrichs, J. Kraus, A. Wuzik, T. Schulz; Non-Dynamic Kinetic Resolution of Configurationally Stable Biaryl Lactones by Reduction with Oxazaborolidine-Activated Borane: AM1 Studies and Experimental Verification; J. Org. Chem. 2000, 65, 2508-2516. | |||||
401) | G. Bringmann, M. Ochse, M. Michel; Gentrymine B, an N-Quaternary Ancistrocladus Alkaloid: Stereoanalysis, Synthesis, and Biomimetic Formation from Gentrymine A; Tetrahedron 2000, 56, 581-585. | |||||
400) | G. Bringmann, M. Wohlfarth, H. Rischer, M. Grüne, J. Schlauer; A new biosynthetic pathway to alkaloids in plants: acetogenic isoquinolines; Angew. Chem. 2000, 112, 1523-1525; Angew. Chem. Int. Ed. 2000, 39, 1464-1466. | |||||
399) | K. Peters, E.-M. Peters, T. Pabst, G. Bringmann; Crystal structure of (P,1’’S,2’’R,5’’S)-menthyl 4,4-di-tert.-butyl-2’-hydroxy-2,3,3’-trimethoxy-6’-methyl-1,1’-biphenyl-6-carboxylate, C6H(OCH3)2[C(CH3)3]CO2(C10H19)C6H(CH3)(OH)(OCH3)[C(CH3) 3]; Z. Kristallogr. NCS 2000, 215, 403-404. | |||||
398) | K. Peters, E.-M. Peters, T. Pabst, G. Bringmann; Crystal structure of (E)-1,2-dibromo-5-tert-butyl-3,4-dimethoxyphenyl)ethene, {C6H(OCH3) 2[C(CH3)3]Br}2C2H2; Z. Kristallogr. NCS 2000, 215, 401-402. | |||||
397) | K. Peters, E.-M. Peters, T. Pabst, G. Bringmann; Crystal structure of 3,8-di-tert-butyl-4,9,10-trimethoxy-1-methyl-dibenzo[b,d]pyran-6-thione, C6H(OCH3)2[C(CH3)3]CSO(C6H)(CH3)(OCH3)[(C(CH3) 3)]; Z. Kristallogr. NCS 2000, 215, 399-400. | |||||
396) | K. Peters, E.-M. Peters, T. Pabst, G. Bringmann; Crystal structure of (P)-4,4’-di-tert-butyl-2,2’,3,3’-tetramethoxy-6,6’-dimethylbiphenyl, {C6H(OCH3) 2(CH3)[C(CH3) 3]}2; Z. Kristallogr. NCS 2000, 215, 397-398. | |||||
395) | G. Bringmann, M. Ochse, R. Götz; First Atropo-Divergent Total Synthesis of Antimalarial Korupensamines A and B - by the ‘Lactone Method'; J. Org. Chem. 2000, 65, 2069-2077. | |||||
394) | G. Brauers, R.A. Edrada, R. Ebel, P. Proksch, V. Wray, A. Berg, U. Gräfe, C. Schächtele, F. Totzke, G. Finkenzeller, D. Marme, J. Kraus, M. Münchbach, M. Michel, G. Bringmann, K. Schaumann; Anthraquinones and Betaenone Derivatives from the Sponge-Associated Fungus Microsphaeropsis Species: Novel Inhibitors of Protein Kinases; J. Nat. Prod. 2000, 63, 739-745. | |||||
393) | G. Bringmann, R. Brückner, R. Mössner, D. Feineis, A. Heils, K.P. Lesch; Effect of trichlororomethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo) on human serotonergic cells; Neurochem. Res. 2000, 25, 837-843. | |||||
392) | G. Bringmann, M. Heubes, M. Breuning, L. Göbel, M. Ochse, B. Schöner, O. Schupp; Atropisomerization Barriers of Configurationally Unstable Biaryl Compounds, Useful Substrates for Atroposelective Conversions to Axially Chiral Biaryls; J. Org. Chem. 2000, 65, 722-728. | |||||
391) | K. Peters, E.-M. Peters, J. Hinrichs, G. Bringmann; Crystal structure of dinaphth[2,1-c:1’,2’-e]thiepin-3-(5H)-thione, (C10H6)CS2(CH2)(C10H6); Z. Kristallogr. NCS 2000, 215, 395-396. | |||||
390) | K. Peters, E.-M. Peters, A. Wuzik, G. Bringmann; Crystal structure of 1,4-dimethyl-6H-benzo[b]naphtho[1,2-d]pyran-6-one, C10H6(COO)C6H2(CH3) 2; Z. Kristallogr. NCS 2000, 215, 393-394. | |||||
389) | K. Peters, E.-M. Peters, A. Wuzik, G. Bringmann; Crystal structure of (2,5-dimethyl)phenyl 1-bromonaphthyl-2-carboxylate, C10H6Br(COO)C6H3(CH3) 2; Z. Kristallogr. NCS 2000, 215, 391-392. | |||||
388) | K. Peters, E.-M. Peters, W. Saeb, G. Bringmann; Crystal structure of 1-bromo-5-isopropoxy-4-methoxy-2-methylnaphthalene, C10H4(OC3H7)(OCH3)(CH3)Br; Z. Kristallogr. NCS 2000, 215, 389-390. | |||||
387) | G. Bringmann, R. Brückner, M Münchbach, D. Feineis, R. God, W. Wesemann, C. Grote, M. Herderich, S. Diem, K.-P. Lesch, R. Mössner, A. Storch; 'TaClo', a Chloral-Derived Mammalian Alkaloid with Neurotoxic Properties; in Neurotoxic Factors in Parkinson's Disease and Related Disorders. (Eds.: A. Storch, M.A. Collins) Kluwer Academics / Plenum Publishers, New York 2000, pp. 145-149. | |||||
386) | K. Peters, E.-M. Peters, R. Brückner, D. Feineis, G. Bringmann; Crystal structure of 2-acetyl-1-tribromomethyl-1,2,3,4-tetrahydro-ß-carboline, C11H10N2(CBr3)(COCH3); Z. Kristallogr. NCS 2000, 215, 221-222. | |||||
385) | G. Bringmann, M. Münchbach, M. Michel; Determination of chiral benzylic alcohols or their ethers, by ruthenium-mediated oxidative degradation; Tetrahedron: Asymmetry 2000, 11, 3167-3176. | |||||
384) | G. Bringmann, M. Ochse, G. Zotz, K. Peters, E.-M. Peters, R. Brun, J. Schlauer; 6-Hydroxyluteolin-7-O-(1’’a-rhamnoside) from Vriesea sanguinolenta Cogn. and Marchal (Bromeliaceae); Phytochemistry 2000, 53, 965-969. | |||||
383) | G. Bringmann; Sir Derek H.R. Barton - an exceptional scientist and extraordinary person - Grateful Memories by a previous postdoctoral Fellow of the gif era; in The Bartonian Legacy (Eds.: A. I. Scott, P. Potier), Imperial College Press, London 2000, pp 99-104. | |||||
382) | G. Bringmann, D. Feineis, W. Saeb, C. Hesselmann, E.-M. Peters, K. Peters; Dimethyl (2S,4S)- and (2R,4S)-5,5-Dimethyl-1,3-thiazolidine-2,4-dicarboxylates, Two Diastereomeric Glyoxylate-Derived Heterocycles; Z. Naturforsch. 2000, 55b, 208-212. | |||||
381) | G. Bringmann, C. Günther, J. Mühlbacher, M.D.L.P. Gunathilake, A. Wickramasinghe; New Tropane Alkaloids from Erythroxylum zeylanicum O.E. Schulz (Erythroxylaceae); Phytochemistry 2000, 53, 409-416. | |||||
380) | K. Peters, E.-M. peters, J. Hinrichs, G. Bringmann; Crystal structure of di(1,3,5-trimethyl-5,6-dihydrobenzo[k]phenanthridin-6-yl) peroxide, (C20H18NO)2; Z. Kristallogr. NCS 2000, 215, 57-58. | |||||
379) | K. Peters, E.-M. peters, R. Brückner, G. Bringmann; Crystal structure of 2-(2'-methyl-propanoyl)-1-tribromomethyl-1,2,3,4-tetrahydro-ß-carboline, C11H10N2[COCH(CH2)3]CBr3; Z. Kristallogr. NCS 2000, 215, 55-56. | |||||
378) | G. Bringmann, H. Rischer, M. Wohlfarth, J. Schlauer, L. Aké Assi; Droserone from cell cultures of Triphyophyllum peltatum (Dioncophyllaceae) and its biosynthetic origin; Phytochemistry 2000, 53, 339-343. | |||||
377) | G. Bringmann, T. Ortmann, D. Feineis, E.-M. Peters, K. Peters; A New Central Binaphthalene Building Block for Michellamine Syntheses; Synthesis, 2000, 383-388. | |||||
376) | G. Bringmann, D. Feineis; Novel Antiparasitic Biaryl Alkaloids from Westafrican Dioncophyllaceae Plants; Act. Chim. Thérapeut. 2000, 26, 151-171. |
1999
375) | G. Bringmann, C. Günther, D.N. Jumbam; Isolation of 4-O-ß-Glucopyranosylcaffeic Acid and Gallic Acid from Cyathea dregei Kunze (Cyatheaceae); Pharm. Pharmacol. Lett. 1999, 9, 41-43. | |||||
374) | G. Bringmann, K. Wolf, A. Haase, T. Lanz, J. Hiort, P. Proksch, W.E.G. Müller; Direct demonstration of spatial water distribution in the sponge Suberites domuncula by in vivo NMR imaging; Mar. Ecol. Progr. Ser. 1999, 189, 307-310. | |||||
373) | G. Bringmann, A. Wuzik, M. Breuning, P. Henschel, K. Peters, E.-M. Peters; Atropo-enantioselective synthesis of an axially chiral C1-symmetric phosphine ligand and its application in the asymmetric hydrosilylation of styrenes; Tetrahedron: Asymmetry 1999, 10, 3025-3031. | |||||
372) | G. Bringmann, H. Rischer, J. Schlauer, L. Aké Assi; In vitro propagation of Ancistrocladus abbreviatus Airy Shaw (Ancistrocladaceae); Plant Cell Tiss. Org. Cult. 1999, 57, 71-73. | |||||
371) | K. Peters, E.-M. Peters, T. Hartung, G. Bringmann; Crystal structure of (P)-1-(2-hydroxy-phenyl)-2-naphthoic acid (1S,2R,5S)-(+)-menthyl ester, C10H6[C6H4(OH)][COOC6H9(CH3)(C3H7)]; Z. Kristallogr. NCS 1999, 214, 553-554. | |||||
370) | K. Peters, E.-M. Peters, A. Wuzik, G. Bringmann; Crystal structure of 2-trifluormethyl-sulfonyloxy-dinaphtho[2,1-b:1',2'-d]pyran-4-one, C21H11O2(OSO2CF3); Z. Kristallogr. NCS 1999, 214, 551-552. | |||||
369) | K. Peters, E.-M. Peters, C. Vedder, G. Bringmann; Crystal structure of 1-(2'-benzoyl-4',6'-dimethylphenyl)-2-methylnaphthalene, [C10H6CH3][C6H2(OCH2C6H5)(OCH3)(CH3) 2]; Z. Kristallogr. NCS 1999, 214, 549-550. | |||||
368) | G. Bringmann, M. Breuning, R. Walter, A. Wuzik, K. Peters, E.-M. Peters; Synthesis of Axially Chiral Biaryls by Atropo-Diastereoselective Cleavage of Configurationally Unstable Biaryl Lactones with Menthol-Derived O-Nucleophiles; Eur. J. Org. Chem. 1999, 3047-3055. | |||||
367) | G. Bringmann, J. Kraus, D. Menche, K. Messer; Elucidation of the Absolute Configuration of Knipholone and Knipholone Anthrone by Quantum Chemical CD Calculations; Tetrahedron 1999, 55, 7563-7572. | |||||
366) | G. Bringmann, M. Breuning, S. Tasler, H. Endress, C.L.J. Ewers, L. Göbel, K. Peters, E.-M. Peters; Atropo-Diastereoselective Cleavage of Configurationally Unstable Biaryl Lactones with Alkali Metal Activated Primary 1-Arylethylamines; Chem. Eur. J. 1999, 5, 3029-3038. | |||||
365) | W.A. Schenk, J. Kümmel, I. Reuther, N. Burzlaff, A. Wuzik, O. Schupp, G. Bringmann; Atropo-Diastereoselective Ring Opening of Biaryl Thionolactones Using [CpRu{(S,S)-CHIRAPHOS}]+ as a Chiral Auxiliary; Eur. J. Inorg. Chem. 1999, 1745-1756. | |||||
364) | K. Peters, E.-M. Peters, C. Vedder, G. Bringmann; Crystal structure of 1-(2'-hydroxy-4',6'-dimethylphenyl)-2-(diphenylphosphanoyloxymethyl)-naphthalene-dichloromethane (1/1), [C10H6(CH2OPO(C6H5)2][C6H(CH3)3(OH)]·CH2Cl2; Z. Kristallogr. NCS 1999, 214, 547-548. | |||||
363) | G. Bringmann, J. Holenz, W. Saeb, L. Aké Assi, K. Hostettmann; Dioncophylline A as a Larvicide Against Aedes aegypti; Pharm. Pharmacol. Lett. 1999, 9, 24-25. | |||||
362) | G. François, B. Chimanuka, G. Timperman, J. Holenz, J. Plaizier-Vercammen, L. Aké Assi, G. Bringmann; Differential sensitivity of erythrocytic stages of the rodent malaria parasite Plasmodium chabaudi chabaudi to dioncophylline B, a highly active naphthylisoquinoline alkaloid; Parasitol. Res. 1999, 85, 935-941. | |||||
361) | G. Bringmann, M. Breuning, S. Tasler; The Lactone Concept: An Efficient Pathway to Axially Chiral Natural Products and Useful Reagents; Synthesis 1999, 525-558. | |||||
360) | K. Peters, E.-M. Peters, C. Günther, G. Bringmann; Crystal structure of 1-hydroxy-8-methoxy-3-methyl naphthalene, C10H5(OCH3)(OH)(CH3); Z. Kristallogr. NCS 1999, 214, 545-546. | |||||
359) | K. Peters, E.-M. Peters, S. Schneider, G. Bringmann; Crystal structure of 1-bromo-2-methyl-dinaphtho[2,1-b:1',2'-d]pyran-4-one, C21H10O2Br(CH3); Z. Kristallogr. NCS 1999, 214, 543-544. | |||||
358) | K. Peters, E.-M. Peters, M. Ochse, G. Bringmann; Crystal structure of 1-bromo-6-hydroxy-4-isopropoxy-8-methylnaphthalene, C10H4(OC3H7)(OH)(CH3)Br; Z. Kristallogr. NCS 1999, 214, 541-542. | |||||
357) | G. Bringmann, M. Wenzel, T.R. Kelly, M.R. Boyd, R.J. Gulakowski, R. Kaminsky; Octadehydromichellamine, a Structural Analog of the Anti-HIV Michellamines without Centrochirality; Tetrahedron 1999, 55, 1731-1740. | |||||
356) | G. Bringmann, M. Münchbach, K. Messer, D. Koppler, M. Michel, O. Schupp, M. Wenzel, A.M. Louis; Cis- and trans-isoshinanolone from Dioncophyllum thollonii: absolute configuration of two 'known', wide-spread natural products; Phytochemistry 1999, 51, 693-699. | |||||
355) | B.W. Nugroho, R.A. Edrada, V. Wray, L. Witte, G. Bringmann, M. Gehling, P. proksch; new Insecticidal Rocaglamide Derivatives and Related Compounds from Aglaia odorata (Meliaceae); Phytochemistry 1999, 51, 367-376. | |||||
354) | K. Peters, E.-M. Peters, S. Schneider, G. Bringmann; Crystal structure of 3-methoxy-2-naphthoic acid phenyl ester, C10H6(OCH3)(COOC6H5); Z. Kristallogr. NCS 1999, 214, 245-246. | |||||
353) | K. Peters, E.-M. Peters, M. Breuning, G. Bringmann; Crystal structure of 1-(2-hydroxy-4,6-dimethoxyphenyl)-2-propyl naphthoate, C10H6(COOC3H7)[C6H2(OCH3)2OH]; Z. Kristallogr. NCS 1999, 214, 251-252. | |||||
352) | K. Peters, E.-M. Peters, C. Vedder, G. Bringmann; Crystal structure of dibenzyldiphenylphosphonium bromide, (C6H5)2(CH2C6H5)2PBr; Z. Kristallogr. NCS 1999, 214, 249-250. | |||||
351) | K. Peters, E.-M. Peters, S. Schneider, G. Bringmann; Crystal structure of 2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-3-yl)-1-methoxynaphthalene, C10H6(OCH3)[C3H2NO(CH3)2]; Z. Kristallogr. NCS 1999, 214, 247-248. | |||||
350) | G. Bringmann, R. God, S. Fähr, D. Feineis, K. Fornadi, F. Fornadi; Identification of the dopaminergic neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline in Human Blood after Intake of the Hypnotic Chloral Hydrate; Anal. Biochem. 1999, 270, 167-175. | |||||
349) | G. Bringmann, M. Rückert, K. Messer, O. Schupp, A.M. Louis; Use of on-line high-perfomance liquid chromatography - nuclear magnetic resonance spectrometry coupling in phytochemical screening studies: rapid identification of metabolites in Dioncophyllum thollonii; J. Chromatogr. A 1999, 837, 267-272. | |||||
348) | G. Bringmann, J. Schlauer, K. Wolf, H. Rischer, U. Buschbom, A. Kreiner, F. Thiele, M. Duschek, L. Aké Assi; Cultivation of Triphyophyllum peltatum (Dioncophyllaceae), the Part-Time Carnivorous Plant; Carniv. Pl. Newslett. 1999, 28, 7-13. | |||||
347) | G. Bringmann, D. Herzberg, G. Adam, F. Balkenhohl, J. Paust; A Short and Productive Synthesis of (R)-a-Lipoic Acid; Z. Naturforsch. 1999, 54b, 655-661. | |||||
346) | G. Bringmann; Naturstoffchemie - neue Wirkstoffe für Medizin und Landwirtschaft; würzburg heute 1999, 67, 17-18. | |||||
345) | G. Bringmann, F. Teltschik, M. Michel, S. Busemann, M. Rückert, R. Haller, S. Bär, A. Robertson, R. Kaminsky; Ancistrobertsonines B, C, and D as well as 1,2-Didehydro-ancistrobertsonine D from Ancistrocladus robertsoniorum; Phytochemistry 1999, 52, 321-332. | |||||
344) | G. Bringmann, M. Ochse, K. Wolf, J. Kraus, K. Peters, E.-M. Peters, M. Herderich, L. Aké Assi, F.K. Tayman; 4-Oxonicotinamide-1-(1'-ß-d-ribofuranoside) from Rothmannia longiflora Salisb. (Rubiaceae); Phytochemistry 1999, 51, 271-276. | |||||
343) | G. Bringmann, D. Menche, M. Bezabih, B.M. Abegaz, R. Kaminsky; Antiplasmodial Activity of Knipholone and Related Natural Phenylanthraquinones; Planta Med. 1999, 65, 757-758. | |||||
342) | G. Wahl, D. Kleinhenz, A. Schorm, J. Sundermeyer, R. Stowasser, C. Rummey, G. Bringmann, C. Fickert, W. Kiefer; Peroxomolybdenum Complexes as Epoxidation Catalysts in Biphasic Hydrogen Peroxide Activation: Raman Spectroscopic Studies and Density Functional Calculations; Chem. Eur. J. 1999, 5, 3237-3251. | |||||
341) | W. Tochtermann, D. Kuckling, C. Meints, J. Kraus, G. Bringmann; Synthesis and absolute configuration of a bi[10]paracyclophane with two chiral planes and one chiral axis; Tetrahedron: Asymmetry 1999, 10, 21-24. | |||||
340) | G. Bringmann, K. Messer, M. Wohlfarth, J. Kraus, K. Dumbuya, M. Rückert; HPLC-CD On-Line Coupling in Combination with HPLC-NMR and HPLC-MS/MS for the Determination of the Full Absolute Stereostructure of New Metabolites in Plant Extracts; Anal. Chem. 1999, 71, 2678-2686. | |||||
339) | G. Bringmann, M. Breuning; Atropo-enantioselective reduction of configurationally unstable biaryl lactones with BINAL-H; Tetrahedron: Asymmetry 1999, 10, 385-390. | |||||
338) | S.E. Drewes, M.M. Horn, O.Q. Munro, N. Ramesar, M. Ochse, G. Bringmann, K. Peters, E.-M. Peters; Stereostructure, conformation and reactivity of a- and b-gardiol from Burchellia bubalina; Phytochemistry 1999, 50, 387-394. | |||||
337) | G. Bringmann, C. Günther; First Total Synthesis of Dioncophylline B, a 7,6'-Coupled Naphthylisoquinoline Alkaloid; Synlett 1999, 216-218. | |||||
336) | G. Bringmann, T. Pabst, D.S. Rycroft, J.D. Connolly; First Synthesis of Mastigophorenes A and B, by Biomimetic Oxidative Coupling of Herbertenediol; Tetrahedron Lett. 1999, 40, 483-486. | |||||
335) | G. Bringmann, W. Saeb, M. Rübenacker; Directed Joint Total Synthesis of the three Naphthylisoquinoline Alkaloids Dioncolactone A, Dioncopeltine A, and 5'-O-Demethyl-dioncophylline A; Tetrahedron 1999, 55, 423-432. | |||||
334) | G. Bringmann, J. Schlauer, M. Rückert, B. Wiesen, K. Ehrenfeld, P. Proksch, F.C. Czygan; Host-Derived Acetogenins Involved in the Incompatible Parasitic Relationship between Cuscuta reflexa (Convolvulaceae) and Ancistrocladus heyneanus (Ancistrocladaceae); Plant Biol. 1999, 1, 581-584. | |||||
333) | G. Bringmann, A. Wuzik, R. Stowasser, C. Rummey, L. Göbel, D. Stalke, M. Pfeiffer, W.A. Schenk; Synthesis and Atropo-Diastereoselective Ring Cleavage of a [Cp*Ru]-Complexed Biaryl Lactone: Experimental and Computational Investigations; Organometallics 1999, 18, 5017-5021. | |||||
332) | B. Janetzky, G. Gille, M. Abdel-mohsen, R. God, W.-D. Rausch, G. Bringmann, H. Reichmann; Effect of highly-halogenated ß-carbolines on dopaminergic cells in culture and on mitochondrial respiration; Drug Dev. Res. 1999, 46, 51-56. | |||||
331) | C. Eder, P. Proksch, V. Wray, K. Steube, G. Bringmann, R.W.M. van Soest, Sudarsono, E. Ferdinandus, L. A. Pattisina, S. Wiryowidagdo, W. Moka; New Alkaloids from the Indopacific Sponge Stylissa Carteri; J. Nat. Prod. 1999, 62, 184-187. | |||||
330) | M. Rückert, M. Wohlfarth, G. Bringmann; Characterization of protein mixtures by ion-exchange chromatography coupled on-line to nuclear magnetic resonance spectroscopy; J. Chromatogr. A 1999, 840, 131-135. | |||||
329) | A. Maier, J. Müller, P. Schneider, H.-P. Fiedler, I. Groth, F.S.K. Tayman, F. Teltschik, C. Günther, G. Bringmann; (2E,4Z)-Decadienoic acid and (2E,4Z,7Z)-decatrienoic acid, two herbicidal metabolites from Streptomyces viridochromogenes Tü 6105; Pestic. Sci. 1999, 55, 733-739. | |||||
328) | G. François, T. Steenackers, L. Aké Assi, W. Steglich, K. Lamottke, J. Holenz, G. Bringmann; Vismione H and structurally related anthranoid compounds of natural and synthetic origin as promising drugs against the human malaria parasite Plasmodium falciparum: structure-activity relationships; Parasitol. Res. 1999, 85, 582-588. | |||||
327) | G. Tóth, A. Simon, T. Linker, F. Rebien, J. Kraus, G. Bringmann; Elucidation of the conformations and absolute configurations of enantiomerically pure tetralin derivatives; Magn. Reson. Chem. 1999, 37, 53-59. | |||||
326) | A. Buske, S. Busemann, J. Mühlbacher, J. Schmidt, A. Porzel, G. Bringmann, G. Adam; Antidesmone, a novel type isoquinoline alkaloid from Antidesma membranaceum (Euphorbiaceae); Tetrahedron 1999, 55, 1079-1086. | |||||
325) | G. Bringmann, M. Rückert, W. Saeb, V. Mudogo; Characterization of metabolites in plant extracts of Ancistrocladus likoko by high-performance liquid chromatography coupled on line with 1H NMR spectroscopy; Magn. Res. Chem. 1999, 37, 98-102. | |||||
324) | G. Bringmann, S. Tasler; The Atropisomer-Selective Synthesis of Biologically Active and Synthetically Useful Chiral Biaryls; in Current Trends in Organic Synthesis (Eds.: C. Scolastico, F. Nicotra) Plenum Publishing Corporation, New York, 1999, pp. 105-116. |
1998
323) | M. Gerlach, A.-Y. Xiao, C. Heim, J. Lan, R. God, D. Feineis, G. Bringmann, P. Riederer, K.-H. Sontag; 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline increases extracellular serotonin and stimulates hydroxyl radical production in rats; Neurosci. Lett. 1998, 257, 17-20. | |||
322) | K. Peters, E.-M. Peters, M. Blank, J.-A. Protzen, D. Feineis, R. God, G. Bringmann; (1R,3S)-1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline-3-carboxamide Methanol Solvate, a Potential Synthetic Precursor to Enantiomerically Pure TaClo; Acta Cryst. 1998, C54, 1005-1007. | |||
321) | C. Fickert, V. Nagel, W. Kiefer, S. Möller, H. Jehle, W. Malisch, R. Stowasser, G. Bringmann; Matrix isolation Raman spectroscopy and photochemistry of (h5-C5H5)(CO)2Fe-SiH2R (R = H, CH3) in comparison with density functional calculations; J. Organomet. Chem. 1998, 566, 225-235. | |||
320) | T. Linker, F. Rebien, G. Tóth, A. Simon, J. Kraus, G. Bringmann; Convenient Catalytic Synthesis and Assignment of the Absolute Configuration of Enantiomerically Pure Dihydronaphthalenes and Their Corresponding Epoxides; Chem. Eur. J. 1998, 4, 1944-1951. | |||
319) | G. Bringmann, M. Wohlfarth, H. Rischer, M. Rückert, J. Schlauer; The Polyketide Folding Mode in the Biogenesis of Isoshinanolone and Plumbagin in Ancistrocladus heyneanus (Ancistrocladaceae); Tetrahedron Lett. 1998, 39, 8445-8448. | |||
318) | J. Fleischhauer, A. Koslowski, C. Repges, K.-P. Gulden, G. Bringmann; The Absolute Configuration of Isoancistrocladine and 'Isohamatine' by Quantumchemical CD-calculations; Z. Naturforsch. 1998, 53a, 993-996. | |||
317) | K. Peters, E.-M. Peters, A. Wuzik, G. Bringmann; Crystal structure of 2-benzyloxy-3-hydroxynaphthalene, C10H6(OH)OCH2C6H5; Z. Kristallogr. NCS 1998, 213, 565-567. | |||
316) | K. Peters, E.-M. Peters, T. Ortmann, G. Bringmann; Crystal structure of methyl 4-amino-3-methoxybenzoate, C6H3NH2(OCH3)COOCH3; Z. Kristallogr. NCS 1998, 213, 563-564. | |||
315) | K. Peters, E.-M. Peters, M. Ochse, G. Bringmann; Crystal structure of ethyl 1-(2-hydroxy-4,6-dimethoxy)naphthyl-2-carboxylate, C10H6(COOC2H5)C6H2(OH)OCH3)2; Z. Kristallogr. NCS 1998, 213, 561-562. | |||
314) | K. Peters, E.-M. Peters, M. Ochse, G. Bringmann; Crystal structure of 2-bromo-5-isopropoxybenzoic acid, C6H3Br(COOH)(OC3H7); Z. Kristallogr. NCS 1998, 213, 559-560. | |||
313) | K. Peters, E.-M. Peters, R. God, S. Fähr, G. Bringmann; Crystal structure of 1-trichloromethyl-2-propanoyl-1,2,3,4-tetrahydro-ß-carboline, C11H10N2(COC2H5)CCl3; Z. Kristallogr. NCS 1998, 213, 557-558. | |||
312) | K. Peters, E.-M. Peters, M. Breuning, A. Wuzik, G. Bringmann; Crystal structure of 2-bromomethyl-1-(2-benzyloxy-4,6-dimethylphenyl)naphthalene, C10H6(CH2Br)C6H2(CH3)2OCH2C6H5; Z. Kristallogr. NCS 1998, 213, 555-556. | |||
311) | G. Bringmann, M. Ochse; The Atropo-Divergent Preparation of Axially Chiral Biaryls Through the 'Lactone Methodology': Total Synthesis of Korupensamine B; Synlett 1998, 1294-1296. | |||
310) | G. Bringmann, U. Dauer, J. Kraus; Hartree Fock Calculations on the Effects of Lewis Acids on the Helimerization Barrier of a Lactone-Bridged Biaryl; Tetrahedron 1998, 54, 12265-12268. | |||
309) | G. Bringmann, M. Breuning; The Atropo-Enantioselective Reduction of Configurationally Unstable Biaryl Hydroxy Aldehydes - A Novel Approach to Axially Chiral Biaryls; Synlett 1998, 634-636. | |||
308) | Y.F. Hallock, J.H. Cardellina II, M. Schäffer, G. Bringmann, G. François, M.R. Boyd; Korundamine A, a Novel HIV-Inhibitory and Antimalarial "Hybrid" Naphthylisoquinoline Alkaloid Heterodimer from Ancistrocladus korupensis; Bioorg. Med. Chem. Lett. 1998, 8, 1729-1734. | |||
307)* | Bringmann, M. Wenzel, M.R. Boyd (U.S. Dept. Of Health and Human Services); Monomeric and Dimeric Arylisoquinoline Alkaloids and Derivatives Thereof; U.S. Patent Application No. 09/001,801 (31.12.97). | |||
306) | G. Bringmann, D. Vitt, J. Kraus, M. Breuning; The ortho-Hydroxy-ortho'-Formyl Biaryl / Lactol Equilibrium: Quantumchemical Studies on Structure and Dynamics; Tetrahedron 1998, 54, 10691-10698. | |||
305) | G. Bringmann, M. Breuning, H. Endress, D. Vitt, K. Peters, E.-M. Peters; Biaryl Hydroxy Aldehydes as Intermediates in the Metal-Assisted Atropo-Enantioselective Reduction of Biaryl Lactones: Structures and Aldehyde-Lactol Equilibria; Tetrahedron 1998, 54, 10677-10690. | |||
304) | G. Bringmann, A. Wuzik, C. Vedder, M. Pfeiffer, D. Stalke; Palladium-mediated intramolecular acylation reaction in the attempted phosphinylation of a sterically hindered trifluoromethylsulfonyloxybiaryl carboxylic ester; J. Chem. Soc., Chem. Commun. 1998, 1211-1212. | |||
303) | K. Peters, E.-M. Peters, S. Harmsen, G. Bringmann; Crystal structure of 2,2-dimethyl-1,3-bis-[3-benzyloxy-4,5-(diphenyl-methylidenedioxy)benzoyloxy]propane, [(C6H5)3C9H4O5]2(CH3)2C3H4; Z. Kristallogr. NCS 1998, 213, 335-336. | |||
302) | G. Bringmann, S. Güssregen, D. Vitt, R. Stowasser; The Atropisomer-Selective Ring Cleavage of Helically Distorted, Configuratively Unstable Biaryl Lactones with a Chiral Metallated N-Nucleophile - the Complete PM3 Mechanistic Course and its Video Presentation; J. Mol. Model. 1998, 4, 165-175. | |||
301) | R. Roscher, G. Bringmann, P. Schreier, W. Schwab; Radiotracer Studies on the Formation of 2,5-Dimethyl-4-hydroxy-3(2H)-furanone in Detached Ripening Strawberry Fruits; J. Agric. Food Chem. 1998, 46, 1488-1493. | |||
300) | G. Bringmann, M. Rückert, J. Schlauer, M. Herderich; Separation and identification of dimeric naphthylisoquinoline alkaloids by liquid chromatography coupled to electrospray ionization mass spectrometry; J. Chromatogr. A 1998, 810, 231-236. | |||
299) | A. Schneider, L.H. Gade, M. Breuning, G. Bringmann, I.J. Scowen, M. McPartlin; Cooperative Reactivity of Unsupported Early-Late Heterobimetallics: Ring Opening and Subsequent Decarbonylation of Biaryllactones; Organometallics 1998, 17, 1643-1645. | |||
298) | G. Bringmann, M. Breuning; Enantioselective addition of diethylzinc to aldehydes using novel axially chiral 2-aminomethyl-1-(2'-hydroxyphenyl)naphthalene catalysts; Tetrahedron: Asymmetry 1998, 9, 667-679. | |||
297) | G. Bringmann, A. Wuzik, J. Kraus, K. Peters, E.-M. Peters; Synthesis and Structure of a Novel Twofold Lactone-Bridged Ternaphthyl; Tetrahedron Lett. 1998, 39, 1545-1548. | |||
296) | G. Bringmann, W. Saeb, R. God, M. Schäffer, G. François, K. Peters, E.-M. Peters, P. Proksch, K. Hostettmann, L. Aké Assi; 5'-O-Demethyldioncophylline A, a New Antimalarial Alkaloid from Triphyophyllum peltatum; Phytochemistry 1998, 49, 1667-1673. | |||
295) | G. Bringmann, S. Tasler, H. Endress, K. Peters, E.-M. Peters; Synthesis of Mukonine and Seven Further 1-Oxygenated Carbazole Alkaloids; Synthesis 1998, 1501-1505. | |||
294) | G. Bringmann, C. Günther, J. Schlauer, M. Rückert; HPLC-NMR On-Line Coupling Including the ROESY Technique: Direct Characterization of Naphthylisoquinoline Alkaloids in Crude Plant Extracts; Anal. Chem. 1998, 70, 2805-2811. | |||
293) | G. Bringmann, M. Wenzel, M. Rübenacker, M. Schäffer, M. Rückert, L. Aké Assi; Dioncophylline D and 8-O-Methyldioncophylline D, 7,8'-Coupled Naphthylisoquinoline Alkaloids from Triphyophyllum peltatum; Phytochemistry 1998, 49, 1151-1155. | |||
292) | E. Urlaub, J. Popp, W. Kiefer, G. Bringmann, D. Koppler, H. Schneider, U. Zimmermann, B. Schrader; FT-Raman investigation of alkaloids in the liana Ancistrocladus heyneanus; Biospectroscopy 1998, 4, 113-120. | |||
291) | G. Bringmann, M. Rückert, C. Günther; Identification of Naphthylisoquinoline Alkaloids by LC-NMR on-line Coupling; in Natural Product Analysis (Eds.: P. Schreier, M. Herderich, H.U. Humpf, W. Schwab), Vieweg, Wiesbaden 1998, pp. 147-150. | |||
290) | G. Bringmann, S. Busemann; Quantumchemical Calculation of CD Spectra: The Absolute Configuration of Biologically Active Natural Products; in Natural Product Analysis (Eds.: P. Schreier, M. Herderich, H.U. Humpf, W. Schwab), Vieweg, Wiesbaden 1998, pp. 195-212. | |||
289) | G. Bringmann, G. François, L. Aké Assi, J. Schlauer; The Alkaloids of Triphyophyllum peltatum (Dioncophyllaceae); Chimia 1998, 52, 18-28. | |||
288) | G. Bringmann, A. Ledermann, J. Holenz, M.-T. Kao, U. Busse, H.G. Wu, G. François; Antiplasmodial Activity of Mono- and Dimeric Carbazoles; Planta Med. 1998, 64, 54-57. | |||
287) | G. Bringmann, T. Pabst, S. Busemann, K. Peters, E.-M. Peters; Atropo-Enantioselective Synthesis of a Simplified Analog of Mastigophorenes A and B; Tetrahedron 1998, 54, 1425-1438. | |||
286) | G. Bringmann, J. Holenz, R. Weirich, M. Rübenacker, C. Funke, M.R. Boyd, R.J. Gulakowski, G. François; First Synthesis of the Antimalarial Naphthylisoquinoline Alkaloid Dioncophylline C, and its Unnatural Anti-HIV Dimer, Jozimine C; Tetrahedron 1998, 54, 497-512. | |||
285) | T. Linker, F. Rebien, J. Kraus, G. Bringmann; Kinetic Resolution of Dihydronaphthalenes by Jacobson Epoxidation: Evidence for Polar Intermediates and Structure Elucidation by Calculation of CD Spectra; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, P. Schreier), Vieweg, Braunschweig, 1998, pp. 71-72. | |||
284) | C. Fickert, V. Nagel, S. Möller, W. Malisch, R. Stowasser, G. Bringmann, A. Materny, W. Kiefer; Photochemistry Studies by Matrix Isolation Raman Spectroscopy; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, P. Schreier), Vieweg, Braunschweig, 1998, pp. 287-290. | |||
283) | W.A. Schenk, T. Beucke, J. Kümmel, F. Servatius, N. Sonnhalter, G. Bringmann, A. Wuzik; Stereo- and Enantioselective Reactions of Thioaldehydes, Thioketones, Thioketenes, and Thionolactones Mediated by Ruthenium Complexes; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, P. Schreier), Vieweg, Braunschweig, 1998, pp. 247-249. | |||
282) | G. Bringmann, M. Breuning, S. Busemann, J. Kraus, C. Rummey, R. Stowasser, D. Vitt, W. Kiefer, C. Fickert, T. Linker, F. Rebien, W. Malisch, S. Möller, J. Sundermeyer, G. Wahl; Calculation of Structures, Activities and Spectroscopic Properties of Metal-Activated Molecules; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, P. Schreier), Vieweg, Braunschweig, 1998, pp. 295-296. | |||
281) | G. Bringmann, M. Breuning, S. Busemann, J. Hinrichs, T. Pabst, R. Stowasser, S. Tasler, A. Wuzik, W.A. Schenk, J. Kümmel, D. Seebach, G. Jaeschke; Metal-Assisted Synthesis and Application of Axially Chiral Biaryl Systems; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, P. Schreier), Vieweg, Braunschweig, 1998, pp. 141-145. | |||
280) | G. Bringmann, J. Holenz, L. Aké Assi, K. Hostettmann; Molluscicidal Activity (Biomphalaria glabrata) of Dioncophylline A - Structure-Activity Investigations; Planta Med. 1998, 64, 485-486. | |||
279) | G. Bringmann; Triphyophyllum peltatum and Related African Lianas - Creative Producers of Pharmaceutically Promising Naphthylisoquinoline Alkaloids; in African Genetic Resources for the Development of Pharmaceuticals and Agrochemicals (Ed.: B.M. Abegaz, J.D. Connolly, M.H.H. Nkunya,), University of Dar es Salaam Publications, Dar es Salaam, Tanzania, 1998, pp. 9-32. | |||
278) | G. Bringmann, R. Götz, P.A. Keller, R. Walter, M.R. Boyd, F. Lang, A. Garcia, J.J. Walsh, I. Tellitu, K.V. Bhaskar, T.R. Kelly; A Convergent Total Synthesis of the Michellamines; J. Org. Chem. 1998, 63, 1090-1097. | |||
277) | G. Bringmann, W. Saeb, G. François, J. Schlauer; Chemical and enzymic syntheses of anti-HIV michellamines and related dimeric naphthylisoquinolines; Pharm. Pharmacol. Lett. 1998, 8, 8-10. | |||
276) | G. Bringmann, M. Rückert, M. Wenzel, C. Günther, K. Wolf, J. Holenz, J. Schlauer; Biological activities and biosynthetic origin of acetogenic isoquinoline alkaloids; Pharm. Pharmacol. Lett. 1998, 8, 5-7. | |||
275) | G. Bringmann, M. Ochse, M. Herderich, C. Günther, K. Wolf, F. Teltschik, M. Rückert; Isolation and structural elucidation of naphthylisoquinoline alkaloids; Pharm. Pharmacol. Lett. 1998, 8, 1-4. | |||
274)* | G. François, G. Bringmann, J.D. Phillipson, M.R. Boyd, G. Timperman, C. Schneider, L. Aké Assi (U.S. Dept. of Health and Human Services); Naphthylisoquinoline Alkaloids, Pharmaceutical Compositions Containing Them and Their Use for the Treatment of Malaria; U.S. Patent Application No. 08/843,582 (16.04.97). | |||
273)* | G. Bringmann, M.R. Boyd, R. Götz, T.R. Kelly (U.S. Dept. of Health and Human Services, Trustees of Boston College, USA); Dimeric Arylisoquinoline Alkaloids and Synthesis Method Thereof; U.S. Patent No. 5,786,482; issued 28.07.1998. | |||
272)* | G. Bringmann, S. Harmsen, M.R. Boyd (U.S. Dept. of Health and Human Services); Dimeric Naphthylisoquinoline Alkaloids and Synthesis Methods Thereof; U.S. Patent No. 5,789,594; issued 04.08.1998. | |||
271)* | G. Bringmann, R. Götz, M.R. Boyd (U.S. Dept. of Health and Human Services); Monomeric Naphthylisoquinoline Alkaloids and Synthesis Methods Thereof; U.S. Patent No. 5,763,613 issued 09.06.1998 US appl. No.08/674,362 (01.07.96). | |||
270) | A. Heguy, P. Cai, P. Meyn, D. Houck, S. Russo, R. Michitsch, C. Pearce, B. Katz, G. Bringmann, D. Feineis, D.L Taylor, A.S Tyms; Isolation and characterization of the fungal metabolite 3-O-methylviridicatin as an inhibitor of tumor necrosis factor a-induced human immunodeficiency virus replication; Antiviral Chem. Chemother. 1998, 9, 149-155. | |||
269) | G. Bringmann, M. Wenzel, M. Rückert, K. Wolf, S. Busemann, M. Schäffer, L. Aké Assi; Dioncophyllinol D, the First 4-Hydroxylated Naphthylisoquinoline Alkaloid, from the Leaves of Triphyophyllum peltatum; Heterocycles 1998, 47, 985-990. | |||
268) | K. Peters, E.-M. Peters, M. Breuning, G. Bringmann; Crystal Structure of 1-ethyl-1-[1-(2-hydroxy-4,6-dimethylphenyl)-2-naphthyl)]propan-1-ol, [C6H2(CH3)2OH][C(OH)(C2H5)2]C10H6; Z. Kristallogr. NCS 1998, 213, 345-346. | |||
267) | K. Peters, E.-M. Peters, L. Göbel, G. Bringmann; Crystal Structure of N-tert-Butoxycarbonyl-1-(S)-2-(1-(R)-hydroxyethyl)phenylethylamine, (CH3CHOH)(COOC4H9)C6H4C2H4NH); Z. Kristallogr. NCS 1998, 213, 343-344. | |||
266) | K. Peters, E.-M. Peters, O. Schupp, A. Wuzik, G. Bringmann; Crystal Structure of 1-methoxynaphthyl-2-carboxylic acid C10H6(OCH3)COOH; Z. Kristallogr. NCS 1998, 213, 341-342. | |||
265) | K. Peters, E.-M. Peters, M. Breuning, O. Schupp, A. Wuzik, G. Bringmann; Crystal Structure of methyl 1-(2-Hydroxy-4,6-dimethylphenyl)naphthyl-2-carboxylate, [(C6H2)(CH3)2OH)](COOCH3)C10H6; Z. Kristallogr. NCS 1998, 213, 339-340. | |||
264) | K. Peters, E.-M. Peters, G. Bringmann, B. Schöner; Crystal Structure of (P,Rs)-[1-(2-Hydroxy-4,6-dimethylphenyl)-2-naphthyl]-p-tolylsulfinylmethylketone [(C10H6)(C6H2(CH3)2OH)]COCH2SO(C6H4CH3); Z. Kristallogr. NCS 1998, 213, 337-338. | |||
263) | K. Peters, E.-M. Peters, R. Götz, G. Bringmann; Crystal Structure of ethyl 8-bromo-4-acetyloxy-5-isopropoxynaphthalene-2-carboxylate, (OC3H7)(OCOCH3)(OCOC2H5)C10H4Br; Z. Kristallogr. NCS 1998, 213, 333-334. | |||
262)* | G. Bringmann, R. Götz, M.R. Boyd, T.R. Kelly; (U.S. Dept. of Health and Human Services; Trustees of Boston College, USA); Synthesis of Arylisoquinoline Alkaloids and Synthesis Methods Thereof; European Patent Application No. 95927269.1; Japanese Patent Application No. 505832/1996; Australian Patent Application No. 31351/95; Canadian Patent Application No. 2,195,646; PCT International Application No. PCT/US 95/09070 (19.07.1995); International Publication No. WO 96/03381 (08.02.1996). Filed: 22.07.94 (Appl.-No. 279,291); 22.07.94 (Appl.-No. 279,339), 13.09.94 (Appl.-No. 305,211), 23.12.94 (Appl.-No. 363,684). U.S. Patent Application No. 363,684 (23.12.1994). | |||
261)* | G. Bringmann, S. Harmsen, R. Götz, M.R. Boyd (U.S. Dept. of Health and Human Services); Monomeric and Dimeric Naphthylisoquinoline Alkaloids and Synthesis Methods Thereof; PCT International Patent Application No. PCT/US 95/09132 (19.07.1995); European Patent Application No. 95928091.8; Japanese Patent Application No. 505844/1996; Australian Patent Application No. 31969/95; Canadian Patent Application No. 2,195,647; International Publication No. WO 96/03382 (08.02.1996). Filed: 22.07.1994 (Appl.-No. 279,291) - 22.07.1994 (Appl.-No. 279,339) U.S. Patent Application No. 279,291 (22.07.1994). | |||
260) | G. François, C. Diakanamwa, G. Timperman, G. Bringmann, T. Steenackers, G. Atassi, M. van Looveren, J. Holenz, J.-P. Tassin, L. Aké Assi, R. Vanhaelen-Fastré, M. Vanhaelen; Antimalarial and cytotoxic potential of four quassinoids from Hannoa chlorantha and Hannoa klaineana, and their structure-activity relationships; Int. J. Parasitol. 1998, 28, 635-640. | |||
259) | G. Bringmann, C. Günther, S. Busemann, M. Schäffer, J.D. Olowokudejo, B. Alo; Ancistroguineines A and B as well as Ancistrotectorine - Naphthylisoquinoline Alkaloids from Ancistrocladus guineënsis; Phytochemistry 1998, 47, 37-43. | |||
258) | G. Bringmann, F. Teltschik, M. Schäffer, R. Haller, S. Bär, M.A. Robertson, M. Isahakia; Ancistrobertsonine A and Related Naphthylisoquinoline Alkaloids from Ancistrocladus robertsoniorum; Phytochemistry 1998, 47, 31-35. | |||
257) | J. Schlauer, M. Rückert, B. Wiesen, M. Herderich, L. Aké Assi, R.D. Haller, S. Bär, K.-U. Fröhlich, G. Bringmann; Characterization of Enzymes from Ancistrocladus (Ancistrocladaceae) and Triphyophyllum (Dioncophyllaceae) Catalyzing Oxidative Coupling of Naphthylisoquinoline Alkaloids to give Michellamines; Arch. Biochem. Biophys. 1998, 350, 87-94. |
1997
256)* | M.R. Boyd, J.H. Cardellina II, K.P. Manfredi, J.W. Blunt, L.K. Pannell, J.B. McMahon, R.J. Gulakowski, G.M. Cragg, G. Bringmann, D. Thomas, J. Jato (U.S. Dept. of Health and Human Services); Process of Preparing Michellamine Compounds; U.S. Patent No. 5,654,432; issued 05.08.1997. | |||
255) | M. Meininger, P.M. Jakob, M. von Kienlin, D. Koppler, G. Bringmann, A. Haase; Radial Spectroscopic Imaging; J. Magn. Reson. 1997, 125, 325-331. | |||
254) | K. Krohn, K. Beckmann, U. Flörke, H.-J. Aust, S. Draeger, B. Schulz, S. Busemann, G. Bringmann; New Palmarumycins CP4a and CP5 from Coniothyrium palmarum: Structure Elucidation, Crystal Structure Analysis and Determination of the Absolute Configuration by CD Calculations; Tetrahedron 1997, 53, 3101-3110. | |||
253) | B.W. Nugroho, B. Güssregen, V. Wray, L. Witte, G. Bringmann, P. Proksch; Insecticidal Rocaglamide Derivatives from Aglaia elliptica and A. harmsiana; Phytochemistry 1997, 45, 1579-1585. | |||
252) | G. Bringmann, M. Ochse, M. Schäffer, R. God, R. Walter, G. François; N,N-Dimethyldioncophyllinium A Iodide - Synthesis, Stereoanalysis, and Antimalarial Activity of the First N-Quaternary Naphthylisoquinolinium Salt; Planta Med. 1997, 63, 544-547. | |||
251) | Y.F. Hallock, J.H. Cardellina II, M. Schäffer, M. Stahl, G. Bringmann, G. François, M.R. Boyd; Yaoundamines A and B, New Antimalarial Naphthylisoquinoline Alkaloids from Ancistrocladus korupensis; Tetrahedron 1997, 53, 8121-8128. | |||
250) | G. Bringmann, D. Feineis, C. Grote, R. God, H.W. Clement, K.-H. Sontag, B. Janetzky, H. Reichmann, W.-D. Rausch, P. Riederer, W. Wesemann; Highly Halogenated Tetrahydro-ß-Carbolines as a New Class of Dopaminergic Neurotoxins; in Pharmacology of Endogenous Neurotoxins (Ed.: A. Moser), Birkhäuser, Boston, Basel, Berlin, 1998, pp. 151-169. | |||
249) | G. François, G. Timperman, W. Eling, L. Aké Assi, J. Holenz, G. Bringmann; Naphthylisoquinoline alkaloids against malaria: evaluation of the curative potential of dioncophylline C and dioncopeltine A against Plasmodium berghei in vivo; Antimicrob. Agents Chemother. 1997, 41, 2533-2539. | |||
248) | G. Bringmann, J. Holenz, B. Wiesen, B. W. Nugroho, P. Proksch; Dioncophylline A as a Growth-Retarding Agent against the Herbivorous Insect Spodoptera littoralis: Structure-Activity Relationships; J. Nat. Prod. 1997, 60, 342-347. | |||
247) | D. Seebach, G. Jaeschke, K. Gottwald, K. Matsuda, R. Formisano, D.A. Chaplin, M. Breuning, G. Bringmann; Resolution of Racemic Carboxylic Acid Derivatives by Ti-TADDOLate Mediated Esterification Reactions - A General Method for the Preparation of Enantiopure Compounds; Tetrahedron 1997, 53, 7539-7556. | |||
246) | G. Bringmann, T. Mader, D. Feineis; Determination of Viridicatin in Penicillium cyclopium by Capillary Gas Chromatography; Anal. Biochem. 1997, 253, 18-25. | |||
245) | G. Bringmann, S. Busemann, K. Krohn, K. Beckmann; Quantumchemical Calculation of CD Spectra: the Absolute Configuration of Palmarumycins CP3 and C2; Tetrahedron 1997, 53, 1655-1664. | |||
244) | Y.F. Hallock, K.P. Manfredi, J.-R. Dai, J.H. Cardellina II, R.J. Gulakowski, J.B. McMahon, M. Schäffer, M. Stahl, K.-P. Gulden, G. Bringmann, G. François, M.R. Boyd; Michellamines D-F, New HIV-Inhibitory Dimeric Naphthylisoquinoline Alkaloids, and Korupensamine E, a New Antimalarial Monomer, from Ancistrocladus korupensis; J. Nat. Prod. 1997, 60, 677-683. | |||
243) | G. Bringmann, R. Stowasser, L. Göbel; DF-studies on a 'stop and go' rotor: steric and electronic factors determining the regio- and stereochemical position of a h6-Cr(CO)3 metal fragment on a helically distorted biaryl ligand; J. Organomet. Chem. 1997, 544, 7-13. | |||
242) | G. François, G. Timperman, T. Steenackers, L. Aké Assi, J. Holenz, G. Bringmann; In vitro inhibition of liver forms of the rodent malaria parasite Plasmodium berghei by naphthylisoquinoline alkaloids - structure-activity relationships of dioncophyllines A and C, and ancistrocladine; Parasitol. Res. 1997, 83, 673-679. | |||
241) | G. Bringmann, A. Wuzik, O. Schupp, K. Peters, E.-M. Peters; 1,3-Di-tert-butyl-6H-benzo[b]naphtho[1,2-d]pyran-6-thione, a Severely Helically Distorted Thionolactone-Bridged Biaryl; Z. Naturforsch. 1997, 52b, 355-358. | |||
240) | M. Meininger, R. Stowasser, P.M. Jakob, H. Schneider, D. Koppler, G. Bringmann, U. Zimmermann, A. Haase; Nuclear Magnetic Resonance Microscopy of Ancistrocladus heyneanus; Protoplasma 1997, 198, 210-217. | |||
239) | N.H. Anh, A. Porzel, H. Ripperger, G. Bringmann, M. Schäffer, R. God, T.V. Sung, G. Adam; Naphthylisoquinoline Alkaloids from Ancistrocladus cochinchinensis; Phytochemistry 1997, 45, 1287-1291. | |||
238) | H. Lanig, M. Hof, G. Bringmann, F.W. Schneider; Time-resolved fluorescence spectroscopy of helically distorted aromatic systems; Chem. Phys. Lett. 1997, 272, 478-483. | |||
237) | K. Krohn, K. Beckmann, H.-J. Aust, S. Draeger, B. Schulz, S. Busemann, G. Bringmann; Generation of the Palmarumycin Spiroacetal Framework by Oxidative Cyclization of an Open Chain Metabolite from Coniothyrium palmarum; Liebigs Ann. 1997, 2531-2534. | |||
236) | G. François, T. Steenackers, G. Timperman, L. Aké Assi, R.D. Haller, S. Bär, M.A. Isahakia, S.A. Robertson, C. Zhao, N.J. De Souza, J. Holenz, G. Bringmann; Retarded Development of Exoerythrocytic Stages of the Rodent Malaria Parasite Plasmodium berghei in Human Hepatoma Cells by Extracts from Dioncophyllaceae and Ancistrocladaceae Species; Int. J. Parasitol. 1997, 27, 29-32. | |||
235) | G. Bringmann, W. Saeb, L. Aké Assi, G. François, A.S. Sankara Narayanan, K. Peters, E.-M. Peters; Betulinic Acid: Isolation from Triphyophyllum peltatum and Ancistrocladus heyneanus, Antimalarial Activity, and Crystal Structure of the Benzyl Ester; Planta Med. 1997, 63, 255-257. | |||
234) | G. Bringmann, D. Koppler, D. Scheutzow, A. Porzel; Determination of Configuration at the Biaryl Axes of Naphthylisoquinoline Alkaloids by Long-Range NOE Effects; Magn. Reson. Chem. 1997, 35, 297-301. | |||
233) | G. Bringmann, J. Hinrichs; Efficient Kinetic Resolution of a Racemic 7-Membered Biaryl Lactone: Enantioselective Synthesis of 2,2'-Dihydroxymethyl-1,1'-binaphthyl; Tetrahedron: Asymmetry 1997, 8, 4121-4126. | |||
| ||||
232) | G. Bringmann, W. Saeb, K. Peters, E.-M. Peters; The Absolute Stereostructure of Dioncophylline A by Anomalous X-ray Dispersion of a 5-Bromo Derivative; Phytochemistry 1997, 45, 1283-1285. | |||
231) | G. Bringmann, F. Pokorny, M. Wenzel, K. Wurm, C. Schneider; Labelled Precursors for Biosynthetic Studies on Naphthylisoquinoline Alkaloids; J. Lab. Compd. Radiopharm. 1997, 39, 29-38. | |||
230) | G. François, G. Timperman, R.D. Haller, S. Bär, M.A. Isahakia, S.A. Robertson, C. Zhao, N.J. De Souza, L. Aké Assi, J. Holenz, G. Bringmann; Growth Inhibition of Asexual Erythrocytic Forms of Plasmodium falciparum and P. berghei in vitro by Naphthylisoquinoline Alkaloid-Containing Extracts of Ancistrocladus and Triphyophyllum Species; Int. J. Pharmacognosy 1997, 35, 55-59. | |||
229) | G. Bringmann, M. Stahl, K.-P. Gulden; Circular Dichroism of Naphthyldihydroisoquinoline Alkaloids: Determination of the Axial Configuration of Yaoundamine A; Tetrahedron 1997, 53, 2817-2822. |
1996
228) | G. Bringmann; African plants as sources of pharmacologically exciting biaryl and quateraryl alkaloids; in Chemistry, Biological and Pharmacological Properties of African Medicinal Plants (Eds.: K. Hostettmann, F. Chinyanganya, M. Maillard, J.-L. Wolfender), University of Zimbabwe Publications, Harare, Zimbabwe, 1996, pp. 1-19. | |||||
227) | G. Bringmann, J. Holenz, L. Aké Assi, T. Steenackers, G. François; Eine potentielle neue Generation von pflanzlichen Wirkstoffen gegen Malaria; Blick - Forschung, Lehre, Dienstleistung (Universität Würzburg) 1996, 85-87. | |||||
226) | G. Bringmann, R. Götz, S. Harmsen, J. Holenz, R. Walter; Biomimetic Total Synthesis of Michellamines A-C; Liebigs Ann. 1996, 2045-2058. | |||||
225) | P. Chau, I.R. Czuba, M.A. Rizzacasa, G. Bringmann, K.-P. Gulden, M. Schäffer; Convergent Synthesis of Naphthylisoquinoline Alkaloids: Total Synthesis of (+)-O-Methylancistrocline; J. Org. Chem. 1996, 61, 7101-7105. | |||||
224) | G. Bringmann, O. Schupp; Der gezielte Aufbau "chiraler Achsen"; Blick - Forschung, Lehre, Dienstleistung (Universität Würzburg) 1996, 72-74. | |||||
223) | G. Bringmann, R. Götz, G. François; Synthesis of Pindikamine A, a Michellamine-Related Dimer of a Non-Natural, 'Skew' Naphthylisoquinoline; Tetrahedron 1996, 52, 13419-13426. | |||||
222) | G. Bringmann, W. Saeb, D. Koppler, G. François; Jozimine A ('Dimeric' Dioncophylline A), A Non-Natural Michellamine Analog with High Antimalarial Activity; Tetrahedron 1996, 52, 13409-13418. | |||||
221) | G. Bringmann, R. Stowasser; Structures, Energetics, and Dynamics of Transition Metal-Activated Lactone-Bridged Biaryl Complexes: a Density-Functional Study; J. Mol. Mod. 1996, 2, 268-269. | |||||
220) | G. Bringmann, D. Feineis; Biologisch aktive Naturstoffe aus tropischen Lianen; Blick - Forschung, Lehre, Dienstleistung (Universität Würzburg) 1996, 45-49. | |||||
219) | G. Bringmann, J. Holenz, L. Aké Assi, C. Zhao, K. Hostettmann; Molluscicidal Activity of Naphthylisoquinoline Alkaloids from Triphyophyllum and Ancistrocladus Species; Planta Med. 1996, 62, 556-557. | |||||
218) | G. François, M. Van Looveren, G. Timperman, B. Chimanuka, L. Aké Assi, J. Holenz, G. Bringmann; Larvicidal activity of the naphthylisoquinoline alkaloid dioncophylline A against the malaria vector Anopheles stephensi; J. Ethnopharmacol. 1996, 54, 125-130. | |||||
217) | G. Bringmann, D. Koppler, B. Wiesen, G. François, A.S. Sankara Narayanan, M.R. Almeida, H. Schneider, U. Zimmermann; Ancistroheynine A, the First 7,8'-Coupled Naphthylisoquinoline Alkaloid from Ancistrocladus heyneanus; Phytochemistry 1996, 43, 1405-1410. | |||||
216) | G. Bringmann, R. God, M. Schäffer; An Improved Degradation Procedure for Determination of the Absolute Configuration in Chiral Isoquinoline and ß-Carboline Derivatives; Phytochemistry 1996, 43, 1393-1403. | |||||
215) | G. Bringmann, R. Stowasser, D. Vitt; Local and non-local DF calculation of the structure of the helically twisted 1,3-dimethyl-{(h6-chromium-tricarbonyl)benzo}[b]naphtho[1,2-d]pyran-6-one: a comparison; J. Organomet. Chem. 1996, 520, 261-264. | |||||
214) | J. Hartung, R. Stowasser, D. Vitt, G. Bringmann; 5-exo or 6-endo? Exploring Transition State Structures in Cyclizations of 4-Penten-1-oxyl Radicals; Angew. Chem. 1996, 108, 3056-3059; Angew. Chem. Int. Ed. Engl. 1996, 35, 2820-2823. | |||||
213) | K.-H. Sontag, C. Heim, T.A. Sontag, W. Kolasiewicz, W. Clement, C. Grote, W. Wesemann, B. Janetzky, H. Reichmann, D. Feineis, R. God, G. Bringmann, D. Rausch, M. Abdel-mohsen, M. Abdel-moneim, W.W. Chan, E. Koutsilieri, B. Zielke, M. Götz, W. Gsell, P. Riederer; Progressive neurodegeneration of the dopaminergic system and inhibition of the complex I induced by the chloral-derived tetrahydro-ß-carboline TaClo; in The Basal Ganglia V (Eds.: C. Ohye, M. Kimura, J.S. McKenzie), Plenum Press, New York and London, 1996, pp. 387-394. | |||||
212) | G. Bringmann, M. Wenzel, H. Bringmann, J. Schlauer, L. Aké Assi; Die "Teilzeit-fleischfressende" Pflanze Triphyophyllum peltatum (Dioncophyllaceae): Nutzung der Fangorgane zur Erforschung der Alkaloidbildung; Der Palmengarten 1996, 60, 32-37. | |||||
211) | G. François, L. Aké Assi, J. Holenz, G. Bringmann; Constituents of Picralima nitida display pronounced inhibitory activities against asexual erythrocytic forms of Plasmodium falciparum in vitro; J. Ethnopharmacol. 1996, 54, 113-117. | |||||
210) | G. Bringmann; Mono- and Dimeric Naphthylisoquinoline Alkaloids - Pharmaceutically and Structurally Exciting Natural Heterocycles with Axial Chirality; Bull. Soc. Chim. Belg. 1996, 105, 601-613. |
1995-1991
209) | G. Bringmann, A. Ledermann, M. Stahl, K.-P. Gulden; Bismurrayaquinone A: Synthesis, Chromatographic Enantiomer Resolution, and Stereoanalysis by Computational and Experimental CD Investigations; Tetrahedron 1995, 51, 9353-9360. | |||
208) | G. Bringmann; Michellamine – Neue antivirale Alkaloide aus afrikanischen Pflanzen; in Phytopharmaka in Forschung und klinischer Anwendung (Eds.: N. Rietbrock, D. Loew), Verlag Steinkopff, Darmstadt, 1995, pp. 113-128. | |||
207) | K.-H. Sontag, C. Heim, T.A. Sontag, R. God, H. Reichmann, W. Wesemann, W.-D. Rausch, P. Riederer, G. Bringmann; Long-term behavioural effects of TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline) after subchronic treatment in rats; J. Neural Transm. 1995, 46 [Suppl.], 283-289. | |||
206) | C. Grote, H.-W. Clement, W. Wesemann, G. Bringmann, D. Feineis, P. Riederer, K.-H. Sontag; Biochemical lesions of the nigrostriatal system by TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline) and derivatives; J. Neural Transm. 1995, 46 [Suppl.], 275-281. | |||
205) | B. Janetzky, R. God, G. Bringmann, H. Reichmann; 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline, a new inhibitor of complex I; J. Neural Transm. 1995, 46 [Suppl.], 265-273. | |||
204) | W.-D. Rausch, M. Abdel-mohsen, E. Koutsilieri, W.W. Chan, G. Bringmann; Studies of the potentially endogenous toxin TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline) in neuronal and glial cell cultures; J. Neural Transm. 1995, 46 [Suppl.], 255-263. | |||
203) | G. Bringmann, R. God, D. Feineis, B. Janetzky, H. Reichmann; TaClo as a neurotoxic lead: improved synthesis, stereochemical analysis, and inhibition of the mitochondrial respiratory chain; J. Neural Transm. 1995, 46 [Suppl.], 245-254. | |||
202) | G. Bringmann, R. God, D. Feineis, W. Wesemann, P. Riederer, W.-D. Rausch, H. Reichmann, K.-H. Sontag; The TaClo concept: 1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo), a new toxin for dopaminergic neurons; J. Neural Transm. 1995, 46 [Suppl.], 235-244. | |||
201) | Y.F. Hallock, J.H. Cardellina II, T. Kornek, K.-P. Gulden, G. Bringmann, M.R. Boyd; Gentrymine B, the First Quaternary Isoquinoline Alkaloid from Ancistrocladus korupensis; Tetrahedron Lett. 1995, 36, 4753-4756. | |||
200) | G. Bringmann, T. Mader; In vivo formation of diazepam-like 1,4-benzodiazepines by Penicillium verrucosum var. verrucosum after administration of 2-aminobenzophenones and glycine; J. Neural Transm. 1995, 101, 169-181. | |||
199) | G. Bringmann, D. Feineis, R. God, S. Fähr, W. Wesemann, H.-W. Clement, C. Grote, W. Kolasiewicz, K.-H. Sontag, C. Heim, T.A. Sontag, H. Reichmann, B. Janetzky, W.-D. Rausch, M. Abdel-mohsen, E. Koutsilieri, M.E. Götz, W. Gsell, B. Zielke, P. Riederer; Neurotoxic effects on the dopaminergic system induced by TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline), a potential mammalian alkaloid: in vivo and in vitro studies; Biogenic Amines 1996, 12, 83-102. | |||
198) | J. Lange, H. Burzlaff, G. Bringmann, O. Schupp; Determination of the Absolute Stereostructure of a Helical Biaryl Lactone by Multiple Scattering X-Ray Experiments; Tetrahedron 1995, 51, 9361-9366. | |||
197) | G. Bringmann, R. Walter, R. Weirich; Synthesis of Axially Chiral Compounds, Part B.2.: Biaryls; in Methods of Organic Chemistry (Houben Weyl) 4th ed. (Eds.: G. Helmchen, R.W. Hoffmann, J. Mulzer, E. Schaumann), vol. E 21a, Thieme, Stuttgart, 1995, pp. 567-587. | |||
196) | G. Bringmann, H. Busse, U. Dauer, S. Güssregen, M. Stahl; Structure and Enantiomerization of Helically Twisted Lactone-Bridged Biaryls: a Theoretical Study; Tetrahedron 1995, 51, 3149-3158. | |||
195) | G. François, G. Timperman, J. Holenz, L. Aké Assi, T. Geuder, L. Maes, J. Dubois, M. Hanocq, G. Bringmann; Naphthylisoquinoline alkaloids exhibit strong growth-inhibiting activities against Plasmodium falciparum and P. berghei in vitro - Structure-activity relationships of dioncophylline C; Ann. Trop. Med. Parasitol. 1996, 90, 115-123. | |||
194) | G. Bringmann, H. Friedrich, G. Birner, M. Koob, K.-H. Sontag, C. Heim, W. Kolasiewicz, S. Fähr, M. Stäblein, R. God, D. Feineis; Determination of the dopaminergic neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-ß-carboline (TaClo) in biological samples using gas chromatography with selected ion monitoring; J. Chromatogr. B, 1996, 687, 337-348. | |||
193) | K. Peters, E.-M. Peters, G. Bringmann, T. Mader; 5-Bromo-2-(chloroacetamido)-benzophenone - a Synthetic Precursor to 6-Bromoviridicatin; Z. Naturforsch. 1996, 51b, 754-755. | |||
192) | G. Bringmann, S. Harmsen, O. Schupp, R. Walter; Metal Assisted "Twisting" of Axes: A Novel Approach to Stereoselective Biaryl Synthesis; in Stereoselective Reactions of Metal-Activated Molecules (Eds.: H. Werner, J. Sundermeyer), Vieweg, Braunschweig, 1995, pp. 137-142. | |||
191)* | G. Bringmann, W. Wesemann, K.-H. Sontag, P. Riederer, W.-D. Rausch, D. Feineis, R. God, H.-W. Clement, C. Grote, W. Gsell, M.E. Götz, B. Zielke; Verwendung halogenierter ß-Carboline als Modellsubstanzen zur Erzeugung neurodegenerativer Erkrankungen; German Patent DE 44 42 097 C2, issued 09.04.98; PCT International patent Application PCT/DE 95/01675 (27.11.1995); European Patent application No. 95 936 988.5; International Publication No. WO 96/16651 (06.06.1996). | |||
190) | R. Pikl, W. Kiefer, I. Reuther, W.A. Schenk, B. Schöner, O. Schupp, G. Bringmann; Synthesis and vibrational spectra of thiobutyrolactone and thiono-benzonaphtho-pyranones and their cyclopentadienyl ruthenium complexes; J. Organomet. Chem. 1995, 494, 89-93. | |||
189) | K. Peters, E.-M. Peters, G. Bringmann, P.A. Keller, M. Schäffer; (1R,3R)-1,3-Dimethyl-8-hydroxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline Hydrochloride - an Enantiomerically Pure Building Block for the Synthesis of Naphthylisoquinoline Alkaloids; Z. Naturforsch. 1995, 50b, 1137-1139. | |||
188) | G. Bringmann, U. Dauer, M. Lankers, J. Popp, U. Posset, W. Kiefer; Structural and electronic influence of aluminum trichloride on a benzonaphthopyranone; J. Mol. Struct. 1995, 349, 431-434. | |||
187) | G. Bringmann, D. Vitt; Stereoselective Ring-Opening Reaction of Axially Prostereogenic Biaryl Lactones with Chiral Oxazaborolidines: An AM1 Study of the Complete Mechanistic Course; J. Org. Chem. 1995, 60, 7674-7681. | |||
186) | Y.F. Hallock, C.B. Hughes, J.H. Cardellina II, M. Schäffer, K.-P. Gulden, G. Bringmann, M.R. Boyd; Dioncophylline A, the Principal Cytotoxin from Ancistrocladus letestui; Nat. Prod. Lett. 1995, 6, 315-320. | |||
185) | G. Bringmann, C. Hesselmann, D. Feineis; Analysis of glyoxylate-derived 1,3-thiazolidines and their precursors after trimethylsilylation by gas chromatography - mass spectrometry; J. Chromatogr. A 1995, 707, 267-281. | |||
184) | G. Bringmann, U. Dauer; The Influence of Lewis Acids on Structure and Dynamics of Lactone-Bridged Biaryls: Quantumchemical Studies; J. Mol. Model. 1995, 1, 88. | |||
183)* | G. Bringmann, H. Reichmann, D. Feineis, R. God, B. Janetzky; Halogenierte ß-Carbolin-Derivate, Verfahren zu ihrer Herstellung und Verwendung dieser Substanzen zur Hemmung der Atmungskette; German patent D.O.S. DE 44 36 190 A1, disclosure 11.04.96; PCT International Patent Application No. PCT/DE 95/01403 (10.10.95); European Patent Application No. 95 935 329.3; International Publication No. WO 96/11197 (18.04.1996). | |||
182) | K. Peters, E.-M. Peters, G. Bringmann, O. Schupp; 1,3-Dimethoxy-6H-benzo[b]naphtho-[1,2-d]pyran-6-thione, a Thionolactone-Bridged Axially Prostereogenic Biaryl; Z. Naturforsch. 1996, 51b, 431-432. | |||
181) | K. Peters, E.-M. Peters, G. Bringmann, S. Harmsen; 1,4-Dibromonaphthalene-2,3-diyl-bis(1'-bromo-2'-naphthoate).CHCl3, a Potential Precursor to Lactone-Bridged Teraryls; Z. Naturforsch. 1996, 51b, 144-146. | |||
180) | G. Bringmann, F. Pokorny; The Naphthylisoquinoline Alkaloids; in The Alkaloids, vol. 46, (Ed.: G.A. Cordell), Academic Press, New York, 1995, pp. 127-271. | |||
179) | K. Peters, E.-M. Peters, G. Bringmann, R. God; 2-Trifluoroacetyl-1-methyl-1,2,3,4-tetrahydro-ß-carboline, a Gaschromatographically Useful Derivative of the Mammalian Alkaloid Eleagnine; Z. Naturforsch. 1995, 50b, 1564-1565. | |||
178)* | G. Bringmann, M.R. Boyd, R. Götz, T.R. Kelly; (U.S. Dept. of Health and Human Services; Trustees of Boston College, USA); Dimeric Arylisoquinoline Alkaloid Compounds; U.S. Patent No. 5,578,729; issued 26.11.1996. Filed: 23.12.94 (Appl.-No. 363,684). | |||
177)* | G. Bringmann, S. Harmsen, M.R. Boyd (U.S. Dept. of Health and Human Services); Dimeric Naphthylisoquinoline Alkaloids and Synthesis Methods Thereof; U.S. Patent No. 5,571,919; issued 05.11.1996. Filed: 22.07.1994 (Appl.-No. 279,339). | |||
176)* | G. Bringmann, R. Götz, M.R. Boyd (U.S. Dept. of Health and Human Services); Monomeric Naphthylisoquinoline Alkaloids and Synthesis Methods Thereof; U.S. Patent No. 5,552,550; issued 03.09.1996. Filed: 22.07.1994 (Appl.-No. 279,291). | |||
175) | T.R. Kelly, A. Garcia, F. Lang, J.J. Walsh, K.V. Bhaskar, M.R. Boyd, R. Götz, P.A. Keller, R. Walter, G. Bringmann; Convergent Total Synthesis of the Michellamines; Tetrahedron Lett. 1994, 35, 7621-7624. | |||
174) | G. Bringmann, K.-P. Gulden, D. Vitt, K. Birken, C. Helf; AdaptivSearch: A novel iterative algorithm for the generation of n-dimensional hypersurfaces using an adaptive numerical strategy; J. Mol. Model. 1995, 1, 161-175. | |||
173) | G. Bringmann, M. Gassen, R. Lardy; 4-Hydroxynon-2-enal, a Cytotoxic Lipid Peroxidation Product, and its C5-Analog 4-Hydroxypent-2-enal: Enantioselective Synthesis and Stereoanalysis; Tetrahedron 1994, 50, 10245-10252. | |||
172) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, R. Götz, P.A. Keller, C. Michel; Crystal structure of 1-(4,6-dimethoxy-2-methylphenyl)-naphthalene; Z. Kristallogr. 1995, 210, 292-293. | |||
171) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, C. Kehr, R.D. Haller, S. Bär, M.A. Isahakia, S.A. Robertson; Crystal structure of droserone in 'biogenic crystals' found under the stem bark of Ancistrocladus robertsoniorum; Z. Kristallogr. 1995, 210, 290-291. | |||
170) | G. Bringmann, S. Harmsen, J. Holenz, T. Geuder, R. Götz, P.A. Keller, R. Walter, Y.F. Hallock, J.H. Cardellina II, M.R. Boyd; 'Biomimetic' Oxidative Dimerization of Korupensamine A: Completion of the First Total Synthesis of Michellamines A, B, and C; Tetrahedron 1994, 50, 9643-9648. | |||
169) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, O. Schupp; Crystal structure of phenyl 1-hydroxy-2-naphthoate, an unexpected product from an attempted aryl aryl coupling reaction; Z. Kristallogr. 1995, 210, 210-211. | |||
168) | G. Bringmann, A. Ledermann, G. François; Dimeric Murrayafoline A, a Potential Bis-Carbazole Alkaloid: 'Biomimetic' Synthesis, Atropoisomer Separation, and Antimalarial Activity; Heterocycles 1995, 40, 293-300. | |||
167) | G. Bringmann, R. Götz, P.A. Keller, R. Walter, P. Henschel, M. Schäffer, M. Stäblein, T.R. Kelly, M.R. Boyd; First Total Synthesis of Korupensamines A and B; Heterocycles 1994, 39, 503-512. | |||
166) | Y.F. Hallock, K.P. Manfredi, J.W. Blunt, J.H. Cardellina II, M. Schäffer, K.-P. Gulden, G. Bringmann, A.Y. Lee, J. Clardy, G. François, M.R. Boyd; Korupensamines A-D, Novel Antimalarial Alkaloids from Ancistrocladus korupensis; J. Org. Chem. 1994, 59, 6349-6355. | |||
165) | G. Bringmann, K.-P. Gulden, Y.F. Hallock, K.P. Manfredi, J.H. Cardellina II, M.R. Boyd, B. Kramer, J. Fleischhauer; Circular Dichroism of Michellamines: Independent Assignment of Axial Chirality by Calculated and Experimental CD Spectra; Tetrahedron 1994, 50, 7807-7814. | |||
164) | M.R. Boyd, Y.F. Hallock, J.H. Cardellina II, K.P. Manfredi, J.W. Blunt, J.B. McMahon, R.W. Buckheit, Jr., G. Bringmann, M. Schäffer, G.M. Cragg, D.W. Thomas, J.G. Jato; Anti-HIV Michellamines from Ancistrocladus korupensis; J. Med. Chem. 1994, 37, 1740-1745. | |||
163)* | G. François, G. Bringmann, J.D. Phillipson, M.R. Boyd, L. Aké Assi, C. Schneider, G. Timperman (U.S. Dept. of Health and Human Services); Antimalarial Naphthylisoquinoline Alkaloids and Pharmaceutical and Medical Uses Thereof; ; U.S. Patent No. 5,639,761; issued 17.06.1997; PCT International Patent Application No. PCT/US 95/01717 (13.02.1995); European Patent Application No. 95910230.2; Japanese Patent Application No. 521360/1995; Australian Patent Application No. 18417/95; Canadian Patent Application No. 2,185,155; International Publication No. WO 95/21616 (17.08.1995). U.S. Patent Application No. 195,547 (14.02.1994). Filed: 14.02.1994 (Appl.-No. 195,547) Chemical Abstracts 1995, 123, 266123u. | |||
162)* | M.R. Boyd, G. François, G. Bringmann, Y.F. Hallock, K.P. Manfredi, J.H. Cardellina II (U.S. Dept. of Health and Human Services); Antimalarial Korupensamines and Pharmaceutical Compositions and Medical Uses Thereof; U.S. Patent No. 5,409,938; issued 25.04.1995; Japanese Patent Application No. 521405/1995; Australian Patent Application No. 17476/1996; PCT International Patent Application No. PCT/US 95/01853 (13.02.1995); International Publication No. WO 95/21826 (26.08.1995). Filed: 14.02.1994 (Appl.-No. 195,260) Chemical Abstracts 1995, 123, 40928y. | |||
161) | G. Bringmann, O. Schupp; Stereocontrolled 'twisting' of biaryl systems – a new pathway to axial chirality; S. Afr. J. Chem. 1994, 47, 83-102. | |||
160) | G. Bringmann, P.A. Keller, K. Rölfing; A New Approach to Atropselective Biaryl Synthesis, Utilizing Chiral Carbon-Carbon Bridges; Synlett 1994, 423-424. | |||
159) | G. François, G. Bringmann, C. Dochez, C. Schneider, G. Timperman, L. Aké Assi; Activities of extracts and naphthylisoquinoline alkaloids from Triphyophyllum peltatum, Ancistrocladus abbreviatus and Ancistrocladus barteri against Plasmodium berghei (Anka strain) in vitro; J. Ethnopharmacol. 1995, 46, 115-120. | |||
158) | G. Bringmann, T. Geuder, S. Harmsen; An Efficient One-Pot Synthesis of 1,4-Diacyl-2,3,5,6-Tetramethoxybenzenes via Biscuprated Precursors; Synthesis 1994, 1143-1145. | |||
157) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, O. Schupp; Crystal structure of 1-isopropyl-4-methyl-6H-benzo[b]-naphtho[1,2-d]pyran-6-one - a configuratively labile, but enantiomerically pure crystallizing helicene-like bridged biaryl; Z. Kristallogr. 1995, 210, 49-50. | |||
156) | G. Bringmann, L. Göbel, K. Peters, E.-M. Peters, H.G. von Schnering; Synthesis, structure, dynamics, and first atropisomer-selective cleavage of the chromium tricarbonyl complex of a lactone-bridged biaryl; Inorg. Chim. Acta 1994, 222, 255-260. | |||
155) | G. Bringmann, U. Dauer, O. Schupp, M. Lankers, J. Popp, U. Posset, A. Weippert, W. Kiefer; The influence of aluminum trichloride on a configuratively labile lactone-bridged biaryl: quantum chemical calculations and optical spectroscopy; Inorg. Chim. Acta 1994, 222, 247-253. | |||
154) | G. Bringmann, R.D. Haller, S. Bär, M.A. Isahakia, S.A. Robertson; Ancistrocladus robertsoniorum J. Léonard: eine erst spät entdeckte Ancistrocladus-Art; Der Palmengarten 1994, 58, 148-153. | |||
153) | G. Bringmann, B. Schöner, K. Peters, E.-M. Peters, H.G. von Schnering; Synthesis and Structure of a Protected Lactolate-Bridged Biaryl with Relevance to the Atropisomer-Selective Ring Opening of Biaryl Lactones; Liebigs Ann. Chem. 1994, 439-444. | |||
152) | G. Bringmann, T. Hartung; Synthesis and Enantiomerization of a Nonracemic 2-Hydroxy-2'-biphenylcarbaldehyde, a Probable Intermediate in the Atropo-Enantioselective Ring Opening of Biaryl Lactones; Liebigs Ann. Chem. 1994, 313-316. | |||
151) | G. Bringmann, M. Rübenacker, W. Koch, D. Koppler, T. Ortmann, M. Schäffer, L. Aké Assi; 5'-O-Demethyl-8-O-methyl-7-epi-dioncophylline A and Its 'Regularly' Configurated Atropisomer from Triphyophyllum peltatum; Phytochemistry 1994, 36, 1057-1061. | |||
150) | G. Bringmann, M. Gassen, S. Schneider; Sensitive, gas chromatography-based stereoanalysis of 4-hydroxyalkenals, toxic products of lipid peroxidation; J. Chromatogr. A 1994, 670, 153-160. | |||
149) | P. Riederer, G. Bringmann, K. Jellinger, W.-D. Rausch, H. Reichmann, K.-H. Sontag, W. Wesemann; Neurotoxine und Neuroprotektion: Membranabhängige radikalische Prozesse - Bedeutung für die Ätiologie und Therapie des Parkinson-Syndroms; in Materialien zur Gesundheitsforschung, Schriftenreihe zum Programm der Bundesregierung Gesundheit 2000 (Ed.: Projektträgerschaft "Forschung im Dienste der Gesundheit"), Verlag für neue Wissenschaft GmbH, Bremerhaven, 1995, pp. 139-157. | |||
148) | G. Bringmann, D. Koppler, A. Porzel, D. Scheutzow; Aufklärung der Achsenkonfiguration an Naphthylisochinolin-Alkaloiden mit Hilfe der Hochauflösungs-NMR-Spektroskopie; GIT Fachz. Lab. 1994, 38, 705-706. | |||
147) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, D. Leimkötter; Crystal structure of racemic trans-2-(4-methylphenyl)-cyclohexyl chloroacetate; Z. Kristallogr. 1994, 209, 979-980. | |||
146) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, R. God; Crystal structure of 2-methyl-1-(1-methylethyl)-quinolinium iodide; Z. Kristallogr. 1995, 210, 34-35. | |||
145) | G. Bringmann, T. Hartung, O. Kröcher, K.-P. Gulden, J. Lange, H. Burzlaff; Synthesis and Absolute Stereostructure of Dinaphth[2,1-c:1',2'-e]oxepin-3-(5H)-one; Tetrahedron 1994, 50, 2831-2840. | |||
144) | G. Bringmann, B. Schöner, O. Schupp, W.A. Schenk, I. Reuther, K. Peters, E.-M. Peters, H.G. von Schnering; Synthesis and ring-opening reactions of cationic ruthenium biaryl thionolactone complexes; J. Organomet. Chem. 1994, 472, 275-284. | |||
143) | G. Bringmann, B. Schöner, O. Schupp, K. Peters, E-M. Peters, H.G. von Schnering; Synthesis, Optical Resolution, and Helimerization of Dinaphtho[2,1-b:1',2'-d]pyran-4-one; Liebigs Ann. Chem. 1994, 91-97. | |||
142) | F. Bökman, H. Bertagnolli, O. Schupp, G. Bringmann; An EXAFS spectroscopic study of the structure of lactone-brigded biaryls coordinated to CpZrCl3 in toluene solution; J. Organomet. Chem. 1994, 474, 117-122. | |||
141) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, O. Schupp; Crystal structure of 2-bromomethyl-1-(2'-methoxy-3,5-dimethyl)-naphthalene; Z. Kristallogr. 1994, 209, 801-802. | |||
140)* | M.R. Boyd, J.H. Cardellina II, K.P. Manfredi, J.W. Blunt, L.K. Pannell, J.B. McMahon, R.J. Gulakowski, G.M. Cragg, G. Bringmann, D. Thomas, J. Jato (U.S. Dept. of Health and Human Services); Michellamine Antiviral Agents, Compositions, and Treatment Methods; U.S. Patent No. 5,455,251; issued 3.10.1995. - Michellamines Useful as Antiviral Agents; PCT International Publication No. WO 94/24108 (27.10.1994). Filed: 19.04.1993 (Appl.-No. 49,824). | |||
139) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, M. Gassen; Crystal structure of Z-2-(6,7-dimethoxytetrahydroisoquino-1-ylidene)-[2-(3,4-dimethoxyphenyl)-ethyl]-acetamide; Z. Kristallogr. 1994, 209, 667-668. | |||
138) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, B. Schwarz, T. Egner; Crystal structure of 3',5'-dimethylphenyl 3-bromo-4,6,7-trimethoxy-2-naphthoate; Z. Kristallogr. 1994, 209, 526-527. | |||
137) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Hartung; Crystal structure of dinaphth[2,1-c:1',2'-e]oxepin-3-(5H)-on, a lactone-bridged chiral binaphthalene; Z. Kristallogr. 1994, 209, 738-739. | |||
136) | G. Bringmann, S. Gramatzki, C. Müller, P. Proksch; Structure-Activity Relationships of Naphthylisoquinoline Alkaloids: Feeding Experiments with the Herbivorous Insect Spodoptera littoralis; Planta Med. 1993, 59 (Suppl.), 624. | |||
135) | G. Bringmann, C. Schneider, F. Pokorny, Hj. Lorenz, H. Fleischmann, A.S. Sankaranarayanan, M.R. Almeida, T.R. Govindachari, L. Aké Assi; The Cultivation of Tropical Lianas of the Genus Ancistrocladus; Planta Med. 1993, 59 (Suppl.), 623-624. | |||
134) | G. Bringmann, C. Schneider, L. Aké Assi; Ancistrobarterine A: A New "Mixed" Ancistrocladaceae/Dioncophyllaceae-Type Alkaloid from Ancistrocladus barteri; Planta Med. 1993, 59 (Suppl.), 620-621. | |||
133) | G. Bringmann, W. Koch, D. Koppler, M. Rübenacker, L. Aké Assi; A New Atropisomeric Dioncophylline A Derivative from Triphyophyllum peltatum; Planta Med. 1993, 59 (Suppl.), 621-622. | |||
132) | G. Bringmann, C. Kehr, U. Dauer, K.-P. Gulden, R.D. Haller, S. Bär, M.A. Isahakia, S.A. Robertson, K. Peters; Ancistrocladus robertsoniorum "Produces" Pure Crystalline Droserone when Wounded; Planta Med. 1993, 59 (Suppl.), 622-623. | |||
131) | G. Bringmann, D. Koppler, D. Scheutzow; The Elucidation of the Relative Configuration at the Biaryl Axes of Naphthylisoquinoline Alkaloids using "Long Range" NMR Effects; Planta Med. 1993, 59 (Suppl.), 580. | |||
130) | G. Bringmann, T. Geuder, F. Pokorny, M. Schäffer, R. Zagst; The Determination of the Absolute Configuration of N-Methylated 1,3-Dimethyltetrahydroisoquinolines, by Oxidative Degradation; Planta Med. 1993, 59 (Suppl.), 619-620. | |||
129) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, D. Leimkötter, E. Urlaub; Crystal structure of racemic trans-2-(4-methylphenyl)-cyclohexanol; Z. Kristallogr. 1994, 209, 799-800. | |||
128) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, L. Göbel; Crystal structure of (S)-1-cyano-2-(1'-phenylethyl)-isoindole; Z. Kristallogr. 1994, 209, 524-525. | |||
127) | T.S. Ertel, S. Hückmann, H. Bertagnolli, G. Bringmann, O. Schupp; EXAFS studies of a chiral rhenium lactone complex and its precursors including multiple scattering calculations; Inorg. Chim. Acta 1994, 222, 27-36. | |||
126) | K. Birken, C. Helf, U. Küster, K.-P. Gulden, M. Stahl, G. Bringmann; Adaptive Hyperflächen im Rechnerverbund; Benutzerinform. Rechenzentr. Univ. Stuttgart 1994, 4-9. | |||
125) | G. François, G. Bringmann, J.D. Phillipson, L. Aké Assi, C. Dochez, M. Rübenacker, C. Schneider, M. Wéry, D.C. Warhurst, G.C. Kirby; Activity of Extracts and Naphthylisoquinoline Alkaloids from Triphyophyllum peltatum, Ancistrocladus abbreviatus and A. barteri against Plasmodium falciparum in vitro; Phytochemistry 1994, 35, 1461-1464. | |||
124) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Hartung; Crystal structure of rac 1-(2-hydroxy-4,6-di-tert-butylphenyl)-2-naphthalenemethanol; Z. Kristallogr. 1994, 209, 740-741. | |||
123) | G. Bringmann, T. Mader, K. Peters, H.G. von Schnering; Unexpected Hydantoin Formation in the Attempted Amidation with 2-Aminobenzophenone of Glyoxylic Acid using Dicyclohexylcarbodiimide; J. Chem. Soc., Chem. Commun. 1993, 12, 1001-1002. | |||
122) | G. Bringmann, R. Zagst, M. Schäffer, Y.F. Hallock, J.H. Cardellina II, M.R. Boyd; The Absolute Configuration of Michellamine B, a "Dimeric", Anti-HIV-Active Naphthylisoquinoline Alkaloid; Angew. Chem. 1993, 105, 1242-1243; Angew. Chem. Int. Ed. Engl. 1993, 32, 1190-1191. | |||
121) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Mader; Crystal structure of N-carbobenzoxy-glycine; Z. Kristallogr. 1994, 209, 456-457. | |||
120) | G. Bringmann, D. Feineis; Induzierte Säugeralkaloide - Thiazolidin-Bildung als Schlüsselschritt zu neuen Therapiekonzepten? Nachr. Chem. Techn. Lab. 1993, 41, 419-427. | |||
119) | G. Bringmann, R. Weirich, H. Reuscher, J.R. Jansen, L. Kinzinger, T. Ortmann; The Synthesis of All Possible Isomeric 6,8-Dioxygenated 1,3-Dimethyl-1,2,3,4-tetrahydroisoquinoline Methyl Ethers - Useful Chiral Building Blocks for Naphthylisoquinoline Alkaloids; Liebigs Ann. Chem. 1993, 877-888. | |||
118) | G. Bringmann, L. Göbel, O. Schupp; Ein konzeptionell neuer Zugang zu axialchiralen Biarylen - Die atropselektive Öffnung stereochemisch labiler cyclischer Biarylvorstufen; GIT Fachz. Lab. 1993, 37, 189-200. | |||
117) | G. Bringmann, L. Kinzinger, T. Ortmann, N.J. de Souza; Isoancistrocladine from Ancistrocladus heyneanus: The First Naturally Occurring N-Unsubstituted cis-Configurated Naphthyltetrahydroisoquinoline Alkaloid; Phytochemistry 1994, 35, 259-261. | |||
116) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, K. Rölfing; Crystal structure of meso-1,2-bis(1'-bromo-2'-naphthyl)-1,2-dihydroxyethane; Z. Kristallogr. 1993, 207, 129-132. | |||
115) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, K. Rölfing; Crystal structure of (E)-1-(1-bromo-2-naphthyl)-2-(3,5-dimethoxyphenyl)ethene; Z. Kristallogr. 1993, 207, 125-128. | |||
114) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, J.R. Jansen; Crystal structure of (1S,3S)-2-benzyl-6-hydroxy-8-methoxy-1,3-dimethyl-1,2,3,4-tetrahydroisoquinoline hydrobromide; Z. Kristallogr. 1993, 207, 133-136. | |||
113) | G. Bringmann, F. Pokorny, M. Stäblein, M. Schäffer, L. Aké Assi; Ancistrobrevine C from Ancistrocladus abbreviatus: the first mixed "Ancistrocladaceae/Dioncophyllaceae-type" naphthylisoquinoline alkaloid; Phytochemistry 1993, 33, 1511-1515; 34, 1663. | |||
112) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, D. Leimkötter; Crystal structure of 2S,4S-2,4-carboxymethyl-5,5-dimethyl-1,3-thiazolidine; Z. Kristallogr. 1993, 208, 223-226. | |||
111) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, C. Hesselmann, D. Leimkötter; Crystal structure of 2S,4S-2,4-carboxymethyl-1,3-dimethylthiazolidine hydrochloride; Z. Kristallogr. 1993, 206, 267-270. | |||
110) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Geuder; Crystal structure of a C2-symmetric Schiff base from 1,4-diacetyl-2,3,5,6-tetramethoxybenzene and (S)-1-phenylethylamine; Z. Kristallogr. 1993, 207, 121-124. | |||
109) | H. Friedrich, G. Bringmann, W. Kolasiewicz, K.-H. Sontag, W.-D. Rausch; "TaClo", ein Chloral-abgeleitetes Tetrahydro-ß-carbolin mit potentiell MP-auslösender Wirkung: Spurennachweis in biologischer Matrix mit Hilfe von GC/MSD und GC/ECD nach selektiver Probenaufarbeitung; in Fortschritte der Analytischen Chemie in Methode und Anwendung, (Ed.: Fachgruppe Analytische Chemie), GDCh-Druck, 1993, pp. 310-312. | |||
108) | G. Bringmann, K.-P. Gulden, H. Busse, J. Fleischhauer, B. Kramer, E. Zobel; Circular Dichroism of Naphthyltetrahydroisoquinoline Alkaloids: Calculation of CD Spectra by Semiempirical Methods; Tetrahedron 1993, 49, 3305-3312. | |||
107) | C. Grimm, P. Proksch, S. Gramatzki, C. Schneider, G. Bringmann; Deleterious Effects of Naphthylisoquinoline Alkaloids on Survival and Growth of Spodoptera littoralis; Planta Med. 1992, 58 (Suppl. 1), 630. | |||
106) | G. Bringmann, S. Gramatzki, R. God, P. Proksch; Enzymatic Biotransformation of Naphthylisoquinoline Alkaloids: First Hints at the Metabolism of Dioncophylline A; Planta Med. 1992, 58 (Suppl. 1), 577-578. | |||
105) | G. Bringmann, K.-P. Gulden, H. Busse, J. Fleischhauer, B. Kramer, E. Zobel; The Calculation of CD Spectra for the Elucidation of the Absolute Configuration of Chiral Biaryls; Planta Med. 1992, 58 (Suppl. 1), 705. | |||
104) | G. Bringmann, L. Kinzinger, H. Busse, C. Zhao; Isolation, Structure Elucidation, and Total Synthesis of Ancistrocline, an Alkaloid of Ancistrocladus tectorius; Planta Med. 1992, 58 (Suppl. 1), 704. | |||
103) | G. Bringmann, R. Weirich, D. Lisch, L. Aké Assi; Ancistrobrevine D: An Unusual Alkaloid from Ancistrocladus abbreviatus; Planta Med. 1992, 58 (Suppl. 1), 703-704. | |||
102) | G. Bringmann, R. Zagst, D. Lisch, L. Aké Assi; Dioncoline A and its Atropisomer: "Inverse Hybrid Type" Ancistrocladaceae/Dioncophyllaceae Alkaloids from Ancistrocladus abbreviatus; Planta Med. 1992, 58 (Suppl. 1), 702-703. | |||
101) | G. Bringmann, T. Ortmann, M. Rübenacker, L. Aké Assi; Dioncophyllacine B: A New 4-Methoxylated Naphthylisoquinoline Alkaloid from the Leaves of Triphyophyllum peltatum; Planta Med. 1992, 58 (Suppl. 1), 701-702. | |||
100) | G. Bringmann, T. Hartung; Atropo-Enantioselective Biaryl Synthesis by Stereocontrolled Cleavage of Configuratively Labile Lactone-Bridged Precursors using Chiral H-Nucleophiles; Tetrahedron 1993, 49, 7891-7902. | |||
99) | J. Sundermeyer, K. Weber, H. Werner, N. Mahr, G. Bringmann, O. Schupp; Unexpected ring-expansion of "axially prostereogenic" biaryl lactones by methylenephosphoranyl-substituted imido complexes of molybdenum and tungsten; J. Organomet. Chem. 1993, 444, C37-C40. | |||
98) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, L. Göbel; Crystal structure of an unexpected adduct of triphenylphosphine oxide to 1-(2'-hydroxy-3',6'-diethylphenyl)-2-bromomethyl)naphthalene; Z. Kristallogr. 1993, 203, 265-268. | |||
97) | G. Bringmann, T. Hartung, L. Göbel, O. Schupp, K. Peters, H.G. von Schnering; Synthesis and Structure of Benzonaphthopyrans; Helically Distorted, Bridged Biaryls with Different Steric Hindrance at the Axis; Liebigs Ann. Chem. 1992, 769-775. | |||
96) | J. Fleischhauer, A. Koslowski, B. Kramer, E. Zobel, G. Bringmann, K.-P. Gulden, T. Ortmann, B. Peter; Messung und Berechnung der CD-Spektren der Biaryl-Alkaloide Ancistrocladein und Dioncophyllein A; Z. Naturforsch. 1993, 48b, 140-148. | |||
95) | T. Grimm, A. Ellebracht, W. Kiefer, G. Bringmann, H. Busse; Vibrational studies in a benzonaphthopyrone: Raman and infrared spectra, normal coordinate analysis and semiempirical calculations; Vibrational Spectrosc. 1993, 5, 181-193. | |||
94) | G. Bringmann, S. Güssregen, H. Busse; "ValleyScan": A new two-bond drive technique for the calculation of potential energy surfaces with less computational effort; J. Comput.-Aided Mol. Design 1992, 6, 505-512. | |||
93) | G. Bringmann, S. Gramatzki, C. Grimm, P. Proksch; Feeding Deterrency and Growth Retarding Activity of the Naphthylisoquinoline Alkaloid Dioncophylline A against Spodoptera littoralis; Phytochemistry 1992, 31, 3821-3825. | |||
92) | G. Bringmann, O. Schupp, K. Peters, L. Walz, H.G. von Schnering; Chiral rhenium complexes [(h5-C5H5)Re(NO)(PPh3)(R,R-lactone)]+BF4- of lactone-bridged biaryls as ligands: synthesis, structure, and stereochemical properties; J. Organomet. Chem. 1992, 438, 117-130. | |||
91) | G. Bringmann, M. Rübenacker, R. Weirich, L. Aké Assi; Dioncophylline C from the Roots of Triphyophyllum peltatum, the First 5,1'-Coupled Dioncophyllaceae Alkaloid; Phytochemistry 1992, 31, 4019-4024. | |||
90) | G. Bringmann, T. Ortmann, R. Zagst, B. Schöner, L. Aké Assi, C. Burschka; (±)-Dioncophyllacine A, a Naphthylisoquinoline Alkaloid with a 4-Methoxy Substituent from the Leaves of Triphyophyllum peltatum; Phytochemistry 1992, 31, 4015-4018. | |||
89) | G. Bringmann, R. Zagst, H. Reuscher, L. Aké Assi; Ancistrobrevine B, the First Naphthylisoquinoline Alkaloid with a 5,8'-Coupling Site, and Related Compounds from Ancistrocladus abbreviatus; Phytochemistry 1992, 31, 4011-4014. | |||
88) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Hartung; Crystal structure of 1,3-di-tert-butyl-6H-benzo[b]naphtho[1,2-d]pyran-6-one - a severely distorted helicene-like bridged biaryl; Z. Kristallogr. 1992, 202, 275-278. | |||
87) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Hartung, O. Schupp; Crystal structure of 6H-benzo[1,2-d]pyran-6-one . 0.5 phenol - a useful, "axially prostereogenic" lactone-bridged biaryl; Z. Kristallogr. 1992, 202, 271-274. | |||
86) | G. Bringmann, L. Kinzinger; (+)-Ancistrocline, a Naphthylisoquinoline Alkaloid from Ancistrocladus tectorius; Phytochemistry 1992, 31, 3297-3299. | |||
85) | G. Bringmann, T. Hartung; First Atropo-Enantioselective Ring Opening of Achiral Biaryls Containing Lactone Bridges with Chiral Hydride-Transfer Reagents Derived from Borane; Angew. Chem. 1992, 104, 782-783; Angew. Chem. Int. Ed. Engl. 1992, 31, 761-762. | |||
84) | G. Bringmann, D. Feineis, C. Hesselmann, S. Schneider, M. Koob, D. Henschler; A "Chemical" Concept for the Therapy of Glyoxylate-Induced Oxalurias; Life Sci. 1992, 50, 1597-1605. | |||
83) | G. Bringmann; A first biosynthetic proposal for the in vivo formation of naturally occurring diazepam-like 1,4-benzodiazepines; J. Neural Transm. 1992, 88, 77-82. | |||
82) | G. Bringmann, T. Hartung; The Atropo-Enantioselective Ring Opening of Achiral Lactone-Bridged Biaryls Using Chirally Modified Aluminum Hydrides; Synthesis 1992, 433-435. | |||
81) | G. Bringmann, T. Hartung, L. Göbel, O. Schupp, C.L.J. Ewers, B. Schöner, R. Zagst, K. Peters, H.G. von Schnering, C. Burschka; Synthesis and Structure of Benzonaphthopyranones, Useful Bridged Model Precursors for Stereoselective Biaryl Syntheses; Liebigs Ann. Chem. 1992, 225-232. | |||
80) | K. Peters, E.-M. Peters, H.G. von Schnering, G. Bringmann, T. Geuder; Crystal structure of a Schiff base from 2,6-dimethoxyacetophenone and (S)-1-phenylethylamine; Z. Kristallogr. 1992, 201, 157-160. | |||
79) | G. Bringmann, C.L.J. Ewers, L. Göbel, T. Hartung, B. Schöner, O. Schupp, R. Walter; Metal-Assisted Atropisomer-Selective Ring Opening of Axially Prostereogenic Biaryl-Lactones; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, A.G. Griesbeck, W. Adam, G. Bringmann, W. Kiefer), Vieweg, Braunschweig, 1992, pp. 183-186. | |||
78) | G. Bringmann, H. Busse, S. Güssregen, B. Schöner, R. Zagst, C. Burschka; Structure and Dynamics of Free and Metallated Benzonaphthopyranones and -Pyrans; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, A.G. Griesbeck, W. Adam, G. Bringmann, W. Kiefer), Vieweg, Braunschweig, 1992, pp. 179-182. | |||
77) | G. Bringmann, C.L.J. Ewers, L. Göbel, T. Hartung, L. Kinzinger, M. Schäffer, B. Schöner, O. Schupp; Synthesis of "Axially Prostereogenic" Bridged Biaryls and their Metal Complexes; in Selective Reactions of Metal-Activated Molecules (Eds.: H. Werner, A.G. Griesbeck, W. Adam, G. Bringmann, W. Kiefer), Vieweg, Braunschweig, 1992, pp. 175-178. | |||
76) | D. Feineis, G. Bringmann, C. Hesselmann; Nachweis Carboxy-substituierter 1,3-Thiazolidine mittels HPLC für ein "chemisches" Konzept zur Behandlung Glyoxylsäure-induzierter Oxalurien; in 11. Königsteiner Chromatographie-Tage 1991, GIT Verlag, Darmstadt, 1991, pp. 204-213. | |||
75) | G. Bringmann, D. Feineis, C. Hesselmann; Determination of 1,3-Thiazolidine-Carboxylic Acids in Urine by Reversed-Phase HPLC after Fluorescence Labelling with Dansyl Chloride; Anal. Lett. 1992, 25, 497-512. | |||
74) | G. Bringmann, C. Hesselmann, D. Feineis; Analysis of glyoxylate-derived 1,3-thiazolidines by ion-pair-assisted reversed-phase chromatography; J. Chromatogr. 1992, 595, 351-354. | |||
73) | A.G. Griesbeck, S. Stadtmüller, H. Busse, G. Bringmann, J. Buddrus; Photoreaktionen zwischen 2-Cyclopenten-1-on und Enolethern; Chem. Ber. 1992, 125, 933-940. | |||
72) | G. Bringmann, H. Friedrich, D. Feineis; Trichloroharmanes as potential endogenously formed inducers of Morbus Parkinson: synthesis, analytics, and first in vivo investigations; J. Neural Transm. 1992, 38 [Suppl.], 15-26. | |||
71) | G. Bringmann, R. Walter, C.L.J. Ewers; Diastereoselective Ring Opening of Achiral Bridged Biaryls Using Chiral O- and N-Nucleophiles: First Atropo-Enantioselective Synthesis of (-)-4,4'-Bis(orcinol); Synlett 1991, 581-583. | |||
70)* | G. Bringmann, M. Rübenacker, E. Ammermann, G. Lorenz, L. Aké Assi (BASF AG); Anwendung von Dioncophyllinen als Fungizide; German Patent D.O.S. DE 41 17 080 A 1, disclosure 26.11.92. - Dioncophyllines A and B as fungicides; European Patent EP 0515 856 A1, disclosure 02.12.1992. | |||
69) | G. Bringmann, F. Pokorny, M. Stäblein, T.R. Govindachari, M.R. Almeida, S.M. Ketkar; On the Biosynthesis of Acetogenic Tetrahydroisoquinoline Alkaloids: First In Vivo Feeding Experiments; Planta Med. (Suppl. 2) 1991, 57, 98. | |||
68) | G. Bringmann, C. Schneider, L. Aké Assi; Direct and Modified Bicyclic Moieties of Naphthylisoquinoline Alkaloids from Ancistrocladus barteri: First Biosynthetic Indicators?; Planta Med. (Suppl. 2) 1991, 57, 10. | |||
67) | G. Bringmann, F. Pokorny, M. Stäblein, L. Aké Assi; Ancistrobrevine C: A "Mixed" Ancistrocladaceae/Dioncophyllaceae-Type Naphthylisoquinoline Alkaloid from Ancistrocladus abbreviatus; Planta Med. (Suppl. 2) 1991, 57, 97-98. | |||
66) | G. Bringmann, R. Zagst, L. Aké Assi; Ancistrobrevine B: A Naphthylisoquinoline Alkaloid with a Novel Coupling Type from Ancistrocladus abbreviatus; Planta Med. (Suppl. 2) 1991, 57, 96-97. | |||
65) | G. Bringmann, T. Ortmann, M. Rübenacker, L. Aké Assi; An Unusual 4-Methoxylated Naphthylisoquinoline Alkaloid from the Leaves of Triphyophyllum peltatum; Planta Med. (Suppl. 2) 1991, 57, 96. | |||
64) | G. Bringmann, J.R. Jansen; Stereocontrolled Ring Opening of Axially Prostereogenic Biaryl Lactones with Hydrogen Nucleophiles: Directed Synthesis of a Dioncophylline A Precursor and (Optionally) its Atropodiastereomer; Synthesis 1991, 825-827. | |||
63) | G. Bringmann, T. Geuder; The Directed Cleavage of Substituted 1-Phenylethylamines: A Novel Route to Enantiomerically Pure b-Amino Acid Esters and b-Lactams; Synthesis 1991, 829-831. | |||
62) | G. Bringmann, M. Rübenacker, T. Geuder, L. Aké Assi; Dioncophylline B, a Naphthylisoquinoline Alkaloid with a New Coupling Type from Triphyophyllum peltatum; Phytochemistry 1991, 30, 3845-3847. | |||
61) | G. Bringmann, F. Pokorny, H.D. Zinsmeister; Ancistrocladus, eine botanisch und chemisch bemerkenswerte Gattung; Der Palmengarten 1991, 55, 13-18. | |||
60) | G. Bringmann, A. Hille, M. Stäblein, K. Peters, H.G. von Schnering; Potential Tryptophan-Derived Alkaloids in Chloral-Treated Patients: Synthesis and Stereostructure; Liebigs Ann. Chem. 1991, 1189-1194. | |||
59) | G. Bringmann, M. Rübenacker, P. Vogt, H. Busse, L. Aké Assi, K. Peters, H.G. von Schnering; Dioncopeltine A and Dioncolactone A: Alkaloids from Triphyophyllum peltatum; Phytochemistry 1991, 30, 1691-1696. | |||
58) | T. Ertel, S. Hückmann, H. Bertagnolli, G. Bringmann, C.L.J. Ewers, G. Erker, I. Hart, C. Sarter; Zirconium complexes of "Axially prostereogenic" benzocoumarin-type lactones: EXAFS determination of the metal environment; in X-Ray Absorption Fine Structure (Ed.: S.S. Hasnain), Ellis Horwood Publishers, New York, 1991, pp. 562-565. | |||
57) | G. Bringmann, R. Zagst, B. Schöner, H. Busse, M. Hemmerling, C. Burschka; Structure of the Naphthyl Isoquinoline Alkaloid Dioncophylline A; Acta Cryst. 1991, C 47, 1703-1705. | |||
56) | G. Bringmann, T. Geuder, M. Rübenacker, R. Zagst; A Facile Degradation Procedure for Determination of Absolute Configuration in 1,3-Dimethyltetra- and Dihydroisoquinolines; Phytochemistry 1991, 30, 2067-2070. | |||
55) | G. Bringmann, J.R. Jansen, H. Busse; An Atropoisomer-Differentiating Reaction for the Chemical Analysis of Axial Chirality and Its Computational Investigation: Proof of the Stereostructure of Dioncophylline A; Liebigs Ann. Chem. 1991, 803-809. | |||
54) | G. Bringmann, D. Feineis, H. Friedrich, A. Hille; Endogenous Alkaloids in Man - Synthesis, Analytics, in vivo Identification, and Medicinal Importance; Planta Med. (Suppl. 1) 1991, 57, 73-84. | |||
53) | G. Bringmann, D. Lisch, H. Reuscher, L. Aké Assi, K. Günther; Atrop-Diastereomer Separation by Racemate Resolution Techniques: N-Methyl-Dioncophylline A and its 7-Epimer from Ancistrocladus abbreviatus; Phytochemistry 1991, 30, 1307-1310. | |||
52) | G. Bringmann, C.L.J. Ewers, R. Walter; Functional Group Interconversion: Use of Carbonyl Derivatives for Heterocyclic Synthesis; in Comprehensive Organic Synthesis, vol. 6, (Ed.: B.M. Trost), Heteroatom Manipulation (Vol.-Ed.: E. Winterfeldt), Pergamon Press, Oxford, 1991, pp. 733-762. |
1990-1986
51)* | G. Bringmann, J.R. Jansen, J.-P. Geisler (BASF AG); Verfahren zur Herstellung von optisch aktiven a-Aminoacetalen; German patent D.O.S. DE 38 43 390 A 1, disclosure 05.07.90. - Preparation of Optically Active a-Amino Acetals from a-Oxo Acetals via Schiff Bases; European Patent EP 0 374 647 B 1, disclosure 15.06.94. | ||||
50) | G. Bringmann, R. Walter, R. Weirich; The Directed Synthesis of Biaryl Compounds: Modern Concepts and Strategies; Angew. Chem. 1990, 102, 1006-1019; Angew. Chem. Int. Ed. Engl. 1990, 29, 977-991. | ||||
49) | G. Bringmann, F. Pokorny, H. Reuscher, D. Lisch, L. Aké Assi; Novel Ancistrocladaceae and Dioncophyllaceae Type Naphthylisoquinoline Alkaloids from Ancistrocladus abbreviatus: a Phylogenetic Link Between the Two Families?; Planta Med. 1990, 56, 496-497. | ||||
48) | G. Bringmann, M. Rübenacker, J.R. Jansen, T. Geuder, L. Aké Assi; Isolation, Structure Elucidation, and Stereoselective Total Synthesis of Novel Alkaloids from Triphyophyllum peltatum; Planta Med. 1990, 56, 495-496. | ||||
47) | G. Bringmann, J.-P. Geisler, T. Geuder, G. Künkel, L. Kinzinger; The Enantioselective Synthesis of Optically Active, Benzene Nucleus-Substituted 1-Phenylethylamines from the Corresponding Acetophenones; Liebigs Ann. Chem. 1990, 795-805. | ||||
46) | G. Bringmann, J.-P. Geisler; A Facile Method for the Asymmetric Synthesis of Enantiomerically Pure 1-(2-Fluorophenyl)-ethylamine; J. Fluor. Chem. 1990, 49, 67-73. | ||||
45) | G. Bringmann, G. Künkel, T. Geuder; Enantiomerically Pure N-Boc Protected ß-Keto-g-Amino Acid Esters from Simple Keto Precursors: A Novel, Stereocontrolled Approach to Statine Derivatives with Any Desired Configuration; Synlett 1990, 253-256. | ||||
44) | G. Bringmann, A. Hille; 1-Trichloromethyl-1,2,3,4-tetrahydro-ß-carboline - A Potential Chloral-Derived Indol Alkaloid in Man; Arch. Pharm. 1990, 323, 567-569. | ||||
43) | G. Bringmann, J.R. Jansen, H. Reuscher, M. Rübenacker, K. Peters, H.G. von Schnering; First Total Synthesis of (-)-Dioncophylline A ("Triphyophylline") and of Selected Stereoisomers: Complete (Revised) Stereostructure; Tetrahedron Lett. 1990, 31, 643-646. | ||||
42) | G. Bringmann, M. Rübenacker, J.R. Jansen, D. Scheutzow, L. Aké Assi; On the Structure of the Dioncophyllaceae Alkaloids Dioncophylline A ("Triphyophylline") and "O-Methyl-Triphyophylline"; Tetrahedron Lett. 1990, 31, 639-642. | ||||
41) | B. Höhl, M. Arnemann, L. Schwenen, D. Stöckl, G. Bringmann, J.R. Jansen, W. Barz; Degradation of the Pterocarpan Phytoalexin (-)-Maackiain by Ascochyta rabiei; Z. Naturforsch. 1989, 44c, 771-776. | ||||
40) | G. Bringmann, H. Reuscher; Atropdiastereoselective Ring Opening of Bridged, "Axial-Prostereogenic" Biaryls: Directed Synthesis of (+)-Ancistrocladisine; Angew. Chem. 1989, 101, 1725-1726; Angew. Chem. Int. Ed. Engl. 1989, 28, 1672-1673. | ||||
39) | G. Bringmann, H. Reuscher; Aryl-Coupling via "Axially Prostereogenic" Lactones: First Total Synthesis of (+)-Ancistrocladisine and (Optionally) its Atropisomer; Tetrahedron Lett. 1989, 30, 5249-5252. | ||||
38) | G. Bringmann, J.-P. Geisler; A Simple, Chiral-Pool-Independent Synthesis of Enantiomerically Pure Alanine-Derived a-Amino Aldehyde Acetals; Synthesis 1989, 608-610. | ||||
37)* | G. Bringmann, J.-P. Geisler, J.R. Jansen (BASF AG); Verfahren zur Herstellung von optisch aktiven 1-Arylethylaminen; German Patent D.O.S. DE 38 19 438 A1, disclosure 19.01.89. | ||||
36) | G. Bringmann, J.R. Jansen; Chiral Economy with Respect to Rotational Isomerism: Rational Synthesis of Hamatine and (Optionally) Ancistrocladine from Joint Helical Precursors; Heterocycles 1989, 28, 137-142. | ||||
35) | G. Bringmann, J.-P. Geisler; Enantiomerically Pure Oxygenated 1-Phenylethylamines from Substituted Acetophenones: By Reductive Amination and Regiospecific Benzylic Cleavage; Tetrahedron Lett. 1989, 30, 317-320. | ||||
34) | G. Bringmann, J.R. Jansen, A. Hille, H. Reuscher; The Stereocontrolled Total Synthesis of Naphthyl Isoquinoline Alkaloids; in 6ème Colloque International, consacré aux Plantes Médicinales et Substances d'Origine Naturelle, Angers, France, 1988, pp. 181-207. | ||||
33) | H. Kessmann, K. Tiemann, J.R. Jansen, H. Reuscher, G. Bringmann, W. Barz; In Vivo Characterization of NADPH: 2'-Hydroxyisoflavone Oxidoreductase in Elicitor Treated Chickpea Cell Cultures and Stereochemical Aspects of the Phytoalexins Medicarpin and Maackiain; in Plant Cell Biotechnology, NATO ASI Series H: Cell Biology, vol. 18, (Eds.: M.S.S. Pais, F. Mavituna, J.M. Novais), Springer Verlag, Berlin, 1988, pp. 231-238. | ||||
32) | G. Bringmann, S. Schneider, K.D. Richter; HPLC-Analytik hochpolarer Pyridoxyl-Alkaloide im Säugerblut; Fresenius Z. Anal. Chem., 1987, 329, 480-484. | ||||
31) | G. Bringmann, A. Hille, M. Zsiška; First Synthesis of 1-Trichloromethyl-6,7-dihydroxy-tetrahydroisoquinoline - an Imaginable Chloral-Derived Mammalian Alkaloid; Heterocycles 1987, 26, 2587-2590. | ||||
30) | G. Bringmann, J.R. Jansen, H.-P. Rink; Regioselective and Atropisomeric-Selective Aryl Coupling to Give Naphthyl Isoquinoline Alkaloids: The First Total Synthesis of (-)-Ancistrocladine; Angew. Chem. 1986, 98, 917-919; Angew. Chem. Int. Ed. Engl. 1986, 25, 913-915. | ||||
29) | G. Bringmann; The Naphthyl Isoquinoline Alkaloids; in The Alkaloids, vol. 29, (Ed.: A. Brossi), Academic Press, New York, 1986, pp. 141-184. | ||||
28) | G. Bringmann, J.R. Jansen; One Pot Preparation of 1,3-Dimethyltetrahydroisoquinolines from their Biosynthetic Diketo Precursors; Heterocycles 1986, 24, 2407-2410. | ||||
27) | G. Bringmann, S. Schneider, A. Hille; Endogene Alkaloide im Säugerorganismus; Nachr. Chem. Tech. Lab. 1986, 34, 222-226. | ||||
26) | G. Bringmann, S. Schneider; Rational Synthesis of Deuterium-Labelled Pyridoxal and Pyridoxyl Alkaloids; Tetrahedron Lett. 1986, 27, 175-178. | ||||
25) | G. Bringmann, S. Schneider; The First Evidence of Endogenous Pyridoxyl Isoquinoline Alkaloids in Mammalian Organisms; Angew. Chem. 1986, 98, 167; Angew. Chem. Int. Ed. Engl. 1986, 25, 177-178. |
1985-1977
24) | G. Bringmann; Biomimetische Synthesen beider Molekülhälften der Ancistrocladus- und der Triphyophyllum-Alkaloide aus gemeinsamen Vorstufen; Liebigs Ann. Chem. 1985, 2126-2134. | ||||||
23) | G. Bringmann, J.R. Jansen; Einfache Synthesen nützlicher Diketo-Bausteine für biomimetische Isochinolin- und Naphthalin-Synthesen; Liebigs Ann. Chem. 1985, 2116-2125. | ||||||
22) | G. Bringmann; Aufbau und Cyclisierung zentral modifizierter ß-Pentaketone: Synthese monocyclischer Isochinolinalkaloid-Vorstufen; Liebigs Ann. Chem. 1985, 2105-2115. | ||||||
21) | G. Bringmann; Isochinoline aus Polyketid-Vorstufen: Ausgefallene Biosynthesewege als Vorbild neuartiger Alkaloid-Synthesen; in Festschrift 35 Jahre Fonds der Chemischen Industrie, Frankfurt, 1985, pp. 151-159. | ||||||
20) | G. Bringmann, S. Schneider; Aufbau und Cyclisierung terminal geschützter ß-Pentaketone: Erste Synthese des Aloenin-Aglycons; Liebigs Ann. Chem. 1985, 765-774. | ||||||
19) | G. Bringmann, D. Heubrock; Sind Alkoholiker verkappte Morphinisten?; Psychologie Heute 1985, 12, 47-51. | ||||||
18) | G. Bringmann, J.R. Jansen; A First and General Route to Naphthylisoquinoline Alkaloids: The Total Synthesis of O-Methyl-tetradehydro-triphyophylline; Tetrahedron Lett. 1984, 25, 2537-2540. | ||||||
17) | G. Bringmann, S. Schneider; Improved Methods for Dehydration and Hydroxy/Halogen Exchange using Novel Combinations of Triphenylphosphine and Halogenated Ethanes; Synthesis 1983, 139-141. | ||||||
16) | G. Bringmann, S. Schneider; Biomimetic First Synthesis of the Aloenin Aglycon; Heterocycles 1982, 19, 1449-1452. | ||||||
15) | G. Bringmann; A Short Biomimetic Synthesis of the Isoquinoline and the Naphthalene Moieties of Ancistrocladus Alkaloids from Common ß-Polycarbonyl Precursors; Tetrahedron Lett. 1982, 23, 2009-2012. | ||||||
14) | G. Bringmann, B. Franck; Extrem selektive Porphyrin-Bildung bei der Cyclisierung verschiedener Oligopyrrole; Liebigs Ann. Chem. 1982, 1272-1279. | ||||||
13) | G. Bringmann, B. Franck; Synthese linearer Di-, Tri-, Tetra- und Pentapyrrole mit natürlichen Seitenketten und günstigen Eigenschaften; Liebigs Ann. Chem. 1982, 1261-1271. | ||||||
12) | G. Bringmann; Isoquinolines and Naphthalenes from ß-Polyketones: Model Reactions for an Extraordinary Alkaloid Biosynthesis; Angew. Chem. 1982, 94, 205; Angew. Chem. Int. Ed. Engl. 1982, 21, 200. | ||||||
11) | D.H.R. Barton, G. Bringmann, W.B. Motherwell; The Selective Modification of Neamine by Radical-induced Deamination; J. Chem. Soc., Perkin Trans. 1, 1980, 2665-2669. | ||||||
10) | D.H.R. Barton, G. Bringmann, G. Lamotte, W.B. Motherwell, R.S. Hay Motherwell, E.A.E. Porter; A Useful Radical-deamination Reaction; J. Chem. Soc., Perkin Trans. 1, 1980, 2657-2664. | ||||||
9) | B. Franck, W. Bock, G. Bringmann, G. Fels, F. Grubenbecher, M. Marsmann, R. Pietschmann, K. Schäpers, U. Spiegel, R. Steinkamp, G. Ufer, C. Wegner; Chemistry of Porphyrin Biosynthesis: Results and Applications; Int. J. Biochem. 1980, 11, 671-679. | ||||||
8) | B. Franck, G. Bringmann, G. Flohr; Sequence Analysis of Ergochrome-Biosynthesis by Competitive Incorporation; Angew. Chem. 1980, 92, 483-484; Angew. Chem. Int. Ed. Engl. 1980, 19, 460-461. | ||||||
7) | G. Bringmann; Endogene Opiate im Menschen, Spontane Bildung von Alkaloid-Drogen; Umschau Wiss. Tech. 1980, 80, 247-248. | ||||||
6) | B. Franck, G. Bringmann, C. Wegner, U. Spiegel; Einfache biomimetische Porphyrin-Synthesen; Liebigs Ann. Chem. 1980, 263-274. | ||||||
5) | B. Franck, C. Wegner, G. Bringmann, G. Fels; Synthese von geschütztem Nor- und Homoporphobilinogen; Liebigs Ann. Chem. 1980, 253-262. | ||||||
4) | D.H.R. Barton, G. Bringmann, W.B. Motherwell; Radical-Induced Reductive Deamination of Amino Acid Esters; Synthesis 1980, 68-70. | ||||||
3) | D.H.R. Barton, G. Bringmann, G. Lamotte, R.S. Hay Motherwell, W.B. Motherwell; Radical Deamination Reactions of Relevance to Aminoglycoside Chemistry; Tetrahedron Lett. 1979, 20, 2291-2294. | ||||||
2) | G. Bringmann; Chemische Mechanismen der Alkohol-Wirkung; Naturwissenschaften 1979, 66, 22-27. | ||||||
1) | B. Franck, G. Fels, G. Ufer, R. Steinkamp, C. Wegner, G. Bringmann; Heterocyclic Chemistry Related to Porphyrins; Heterocycles 1977, 6, 1541-1546. |