Research Interests

Research activities in our group are focused on the design and synthesis of novel porous materials such as covalent organic cage compounds as well as covalent organic or metal-organic frameworks. Based on a molecular design approach, we explore tailor-made design strategies for the efficient formation of such structures on various hierarchy levels. Thereby, synthetic modifications on the lowest level of the small molecule precursors are at the centerpiece of our daily lab work. On this basis, we aim to obtain integrative systems with a precise spatial arrangement of multiple functional units utilizing self-sorting phenomena and directional approaches.

Methods and Techniques

Organic synthesis, solvothermal synthesis, crystallization, dynamic covalent chemistry; Structural characterization by 1D and 2D NMR, MS, UV/Vis, X-ray, PXRD, sorption measurements, TGA.

Key Publications

B. Gole et. al., Angew. Chem. Int. Ed. 2018, 57, 846–850, Microtubular Self-Assembly of Covalent Organic Frameworks
DOI: 10.1002/anie.201708526

A. Kraft et. al., Chem. Eur. J. 2017, 23, 15864–15868, Metal-Based Diversity for Crystalline Metal-Fullerene Frameworks
DOI: 10.1002/chem.201703709

S. Klotzbach and F. Beuerle, Chem. Int. Ed. 2015, 54, 10356–10360, Shape-Controlled Synthesis and Self-Sorting of Covalent Organic Cage Compounds
DOI: 10.1002/anie.201502983

S. Klotzbach, T. Scherpf and F. Beuerle, Chem. Commun. 2014, 50, 12454–12457, Dynamic covalent assembly of tribenzotriquinacenes into molecular cubes
DOI: 10.1039/c4cc01794c


CV of PD Dr. Florian Beuerle

2012-2016Habilitation, Faculty of Chemistry and Pharmacy, University of Würzburg
since 2010Junior Research Group Leader, Institute of Organic Chemistry, Center for Nanosystems Chemistry, University of Würzburg
2008-2010Feodor Lynen postdoctoral fellow (AvH), Northwestern University, Evanston/IL (USA)
2008Dr. rer. nat. (Organic Chemistry), University of Erlangen

Background and Motivation

Coming from a synthetic and supramolecular background, we try to push the limits of traditional synthesis towards the controlled formation of molecular architectures with ever increasing complexity. Directional self-assembly of small building blocks under dynamic conditions serves as our method of choice to obtain not only aesthetically appealing structures but also materials with tempting potential for specific host-guest interactions, organic electronics or energy-related issues.


Priv.-Doz. Dr. Florian Beuerle
Phone: +49 931 31-83603
Fax:      +49 931 31-836030