Jun.-Prof. Ann-Christin Pöppler

    Institute of Org. Chemistry
    University of Würzburg
    Am Hubland
    97074 Würzburg, Germany

    Tel.: +49 (0)931-3185620




    Logo & Link Institut für Organische Chemie

    Key Research Interests

    We investigate drugs in a polymer matrix by approaching the subject from different angles making use of the versatile toolbox of NMR spectroscopy in combination with other complementary techniques:(1) A thorough understanding of the drug molecules and their interactions in the solid state and in solution as well as (2) the synthesis and analysis of different polymer systems/hydrogels by anisotropic NMR will be the foundation for (3) the study of the interactions of these drugs with the polymer matrix and their subsequent release. Based on these insights, more specific polymers can be designed and (4) the response of stimuli-sensitive and degradable polymers can be monitored.

    Methods and Techniques: 1D and 2D NMR in isotropic solutions & in anisotropic environments, NMR Crystallography (solid-state NMR in combination with DFT calculations and diffraction methods), DSC, TGA.

    Recent Publications

      Filling Blank Spots on the Map: Identification of Ligand Binding Modes and Interacting Water Molecules for Brd4-BD1 by WaterLOGSY Titrations


    Ann-Christin Pöppler
    J. Med. Chem., 2017, 60 (21), 8706–8707
    DOI: 10.1021/acs.jmedchem.7b01497


    A Combined NMR Crystallographic and PXRD Investigation of the Structure-Directing Role of Water Molecules in Orotic Acid and its Lithium and Magnesium Salts

    Ann-Christin Pöppler, David Walker, Steven P. Brown
    CrystEngComm 2017, 19, 224-236      
    DOI: 10.1039/C6CE02101H



    Aktuelles und Termine

    FG-NMR in Bayreuth

    Congratulations, Sebastian!

    Small Molecules are Still Hot!


    Juniorprofessur für Organische Strukturchemie am Institut für Organische Chemie
    Am Hubland
    97074 Würzburg

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