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    Congratulations - Nobel prize in medicine awarded to hypoxia researchers

    10/08/2019

    William G Kaelin, Sir Peter Ratcliffe and Gregg L Semenza share award for work on how cells adapt to oxygen availability.

    Hypoxia inducible factors (HIF) play an important role in our everyday physiology. Hypoxia (a low tissue oxygen content) is a feature of many diseases including chronic lung disease, lung disease and many cancers.

    We had the privilege to cooperate with Professor Sir Peter Ratcliffe, a researcher at the University of Oxford, on the awarded topic. 

     

    Structure of Factor-inhibiting Hypoxia-inducible Factor (HIF) Reveals Mechanism of Oxidative Modification of HIF-1α

    Journal of Biological Chemistry 2003, 278, 1802-1806.

    Jonathan M. Elkins, Kirsty S. Hewitson, Luke A. McNeill, Jürgen F. Seibel, Imre Schlemminger, Christopher W. Pugh, Peter J. Ratcliffe and Christopher J. Schofield

     

    See also: Nobel prize in medicine awarded to hypoxia researchers