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Institute of Org. Chemistry
University of Würzburg
Am Hubland
97074 Würzburg, Germany

Tel.: +49 (0)931-31 85620
Email: ann-christin.poeppler@uni-wuerzburg.de

--- Office now at CNC (Center for Nanosystem Chemistry) ---

Profiles

ORCID
0000-0002-0624-1708

Curriculum Vitae

Group Video

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Key Research Interests

We investigate drugs in polymer matrices by approaching the subject from different angles making use of the versatile toolbox of NMR spectroscopy in combination with other complementary techniques:(1) A thorough understanding of the drug molecules and their interactions in the solid state and in solution as well as (2) the synthesis and analysis of different polymer systems/hydrogels by anisotropic NMR will be the foundation for (3) the study of the interactions of these drugs with the polymer matrix and their subsequent release. Based on these insights, more specific polymers can be designed and (4) the response of stimuli-sensitive and degradable polymers can be monitored.

Methods and Techniques: 1D and 2D NMR in isotropic solutions & in anisotropic environments, solid-state NMR at moderate and fast MAS in combination with DFT calculations and diffraction methods, DSC, TGA.

Research Highlight

Recent Publications

^{Unravelling an Alternative Mechanism in Polymer Self-Assemblies: An Order-Order Transition with Unusual Molecular Interactions between Hydrophilic and Hydrophobic Polymer Blocks}

L. Hahn, T. Zorn, J. Kehrein, T. Kielholz, A.-L. Ziegler, S. Forster, B. Sochor, E. S. Lisitsyna, N. A. Durandin, T. Laaksonen, V. Aseyev, C. Sotriffer, K. Saalwächter, M. Windbergs, A.-C. Pöppler and R. Luxenhofer

ACS Nano. 2023,
Accepted for publication

https://doi.org/10.1021/acsnano.3c00722

^{Solid microemulsion preconcentrates on pH responsive metal-organic framework for tableting}