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Deutsch Intern
    THE BRINGMANN GROUP: BIOACTIVE COMPOUNDS FROM NATURE

    Contact:

    Prof. Dr. Dr. h.c. mult. Gerhard Bringmann

    Institut für Organische Chemie
    Am Hubland
    97074 Würzburg, Germany

    Phone: +49 931 31 85323
    Fax: +49 931 31 84755
    bringman@chemie.uni-wuerzburg.de

    Key research interests

    Our group pursues natural products chemistry with structural, biosynthetic, and pharmacological facets. We approach this topic in a broad, highly interdisciplinary way, applying – and, in part, newly developing – novel efficient methods of analytical, synthetic, computational, and medicinal chemistry.

    Our special interest is devoted to stereochemical questions of stereogenic centers (C- or N-based), axes (C,C or C,N, sp2-sp2 or sp2-sp3), of chiral ‘planes’ or helices, both analytically and synthetically, and we test and optimize their bioactivities. Starting from rewarding sources (mostly tropical plants), we search for novel antiparasitic, antileukemic, and anticancer natural products including the elucidation of their full absolute stereostructures. Using biomimetic or non-biomimetic strategies, we elaborate synthetic pathways to the most rewarding metabolites; as an example, we have developed the 'lactone method' for the atropo-selective construction of highly hindered axially chiral biaryl and hetero-biaryl systems of any desired configuration.

    more

    733)

    K. Ndjoko loset, G. Bringmann; Une nouvelle génération de professeurs avec BEBUC; AfriSciTec 2018. http://www.afriscitech.com/fr/actualites/politique/440-une-nouvelle-generation-de-professeurs-avec-bebuc

    732)

    S. Awale, D. F. Dibwe, C. Balachandran, S. Fayez, D. Feineis, B. K. Lombe, G. Bringmann; Ancistrolikokine E3, a 5,8'-Coupled Naphthylisoquinoline Alkaloid, Eliminates the Tolerance of Cancer Cells to Nutrition Starvation by Inhibition of the Akt/mTOR/Autophagy Signaling Pathway; J. Nat. Prod. 201881, 2282-2291.

    For more publications of the Bringmann Group, please visit our publications section

    Extraordinary Professorship für Gerhard Bringmann

    Besuch aus dem Kongo und neue Kooperation mit Südafrika

    BEBUC: jetzt 192 Exzellenz-Stipendiaten im Kongo

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    Contact

    Lehrstuhl für Organische Chemie I
    Am Hubland
    97074 Würzburg

    Phone: +49 931 31-85322
    Fax: +49 931 31-84755
    Email

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