The summer school will take place from 28th of July until 2nd of August 2019 and will offer a wide variety of different speakers and topics around the chemistry of nucleic acids.
The course sets the focus on the fascinating chemistry of RNA and DNA and their modified forms. RNA plays multiple different roles in nature and these are further expanded and regulated by about 150 natural chemically modified nucleosides. Synthetic nucleic acids as well as small molecules targeting RNA and DNA structures are explored for diagnostic and therapeutic strategies. Moreover, nucleic acids with new functions are developed in the laboratory, including ribozymes and aptamers for various applications to investigate biological systems.
The lectures will give an overview of recent developments in the field and present exciting new discoveries. Students are also encouraged to present their research projects on posters, and some abstracts will be selected for short talks. The summer school brings together students and teachers to discuss challenges and future directions in nucleic acids chemistry and synthetic biology. It is a great opportunity for networking and the exchange of ideas and experiences. Students at the advanced master level as well as PhD students are encouraged to apply.
- Synthesis and analysis of modified nucleosides and nucleic acids
- In vitro selection and engineering of functional nucleic acids: aptamers and ribozymes
- RNA labeling and imaging
- DNA/RNA bioconjugation
- Nucleic acid structural biology
- Supramolecular nucleic acid architectures
- Small molecules targeting nucleic acid structures
- Chemical biology of RNA modifications
- Genome engineering (CRISPR/Cas)
- Therapeutic nucleic acids
Lectures will be held by international experts in the field of nucleic acid chemistry and synthetic biology as well as by local experts from the Julius-Maximilians-University Würzburg.
- Chase Beisel, Würzburg
- Michal Hocek, Prag
- Claudia Höbartner, Würzburg
- Caroline Kisker, Würzburg
- Christoph Kreutz, Innsbruck
- Günter Mayer, Bonn
- Ronald Micura, Innsbruck
- P. I. Pradeepkumar, Bombay
- Jürgen Seibel, Würzburg
- Redmond Smyth, Würzburg
- S. G. Srivatsan, Pune
- Hans-Achim Wagenknecht, Karlsruhe